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Indications for and techniques of keratoplasty at Vietnam National Institute of Ophthalmology

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International Journal of Ophthalmology(English edition) 2016年第3期9卷 379-383页

作者： pham Ngoc Dong Truong nhu Han Anthony J.Aldave Hoang thi Minh Chau Vietnam National Institute of Ophthalmology HanoiVietnam Stein Eye Institute the University of California Los Angeles CA 90095-7003 USA

AIM： To report the indications for and techniques of corneal transplantation at Vietnam National Institute of Ophthalmology （VNIO） over a period of 12y （2002-2013）, METHODS： Records of patients who had undergone corneal transplantation at VNIO from January 1, 2002 to January 1, 2014 were reviewed to determine the indication for and type of corneal transplant performed. Patient age, gender, indication for corneal transplantation and surgical technique were recorded and analyzed. RESULTS： Corneal transplantation were underwent in 1390 eyes of 1278 patients with a mean age of 44.9±18.1y during the period under review. The most common indication was infectious corneal ulcer （n=670; 48.2%）, followed by corneal scar （n=333, 24.0% ）, corneal dystrophy （n=138, 9.9%） and failed graft （n=112, 8.1%）. Nearly all procedures performed were penetrating keratoplasty （n=1300, 93.5% ）, with a few lamellar keratoplasty procedures performed： lamellar keratoplasty （n=52, 3.7%）, Descemet＇s stripping automated endothelial keratoplasty （n =27, 1.9% ） and deep anterior lamellar keratoplasty （n =11, 0.8%）.CONCLUSION： While the most common indication for keratoplasty was infectious keratitis, nearly all indications for corneal transplantation were managed with penetrating keratoplasty, However, lamellar keratoplasty techniques, including deep anterior lamellar keratoplasty and Descemet＇s stripping automated endothelial keratoplasty, are being performed with increasing frequency for isolated stromal and endothelial disorders, respectively,

关键词： penetratingkeratoplasty, lamellarkeratoplasty endothelial keratoplasty indication for keratoplasty technique of keratoplasty

Role of Aedes aegypti and Aedes albopictus during the 2011 dengue fever epidemics in Hanoi, Vietnam

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Asian Pacific Journal of Tropical Medicine 2015年第7期8卷 541-546页

作者： pham thi Kim Lien Vu Trong Duoc Laurent Gavotte Emmanuel Cornillot Phan thi Nga Laurence Briant Roger Frutos Tran nhu Duong National Institute of Hygiene and Epidemiology CPBS UMR 5236 CNRS-UM1-UM2 1919 route de Mende 34293 Montpellier Cedex 5France ISEM UMR 5554 CNRS-UM2-IRD Université Montpellier 2 CC065 Place E. Bataillon34095 Montpellier Cedex 5 France CPBS UMR 5236 CNRS-UM1-UM2 1919 route de Mende 34293 Montpellier Cedex 5France Intertryp UMR 17 Cirad-IRD Campus International de Baillarguet34398 Montpellier Cedex 5 France

Objective: To record the human cases of dengue fever(DF) and investigate the Aedes mosquito species circulating during the Hanoi 2011 DF epidemics. Methods: 24 different outbreak points were recorded in 8 districts between August and December 2011. Results: 140 patients were hospitalized following dengue diagnostic with a predominance of males(59.3%) and the 15-34 age class. Only DENV-1(11.27%) and DENV-2(88.73%) serotypes were detected in human samples. Mosquito sampling performed in and around patients households revealed the predominance of Aedes aegypti(95.15%) versus Aedes albopictus(4.85%). There is a positive correlation between the population density of Aedes aegypti and the number of human cases and duration of outbreaks. Conclusions: this was not observed for Aedes albopictus. 3 pools of Aedes aegypti were positive with dengue virus, two with DENV-1 and one with DENV-2.

关键词： Aedes aegypti Aedes albopictus Dengue Vector density

Investigation of Polymorphisms in Coding Region of OsHKT1in Relation to Salinity in Rice

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Rice science 2016年第6期23卷 334-338页

作者： pham quynh-hoa tran xuan-an nguyen thi-nha-trang tran thi-thuy-anh hoang hai-yen nguyen thi-hong-van tang thi-hanh do thi-phuc Faculty of Biology VNU University of ScienceHanoi334 Nguyen TraiThanh XuanHanoiVietnam Faculty of Agronomy Vietnam National University of AgricultureNgo Xuan Quang StreetTrau QuyGia LamHanoiVietnam

Rice （Oryza sativa） is sensitive to salinity, but the salt tolerance level differs among cultivars,which might result from natural variations in the genes that are responsible for salt tolerance. High-affinitypotassium transporter （HKTs） has been proven to be involved in salt tolerance in plants. Therefore, wescreened for natural nucleotide polymorphism in the coding sequence of OsHKT1, which encodes the HKTprotein in eight Vietnamese rice cultivars differing in salt tolerance level. In total, seven nucleotidesubstitutions in coding sequence of OsHKT1 were found, including two non-synonymous and five synonymoussubstitutions. Further analysis revealed that these two non-synonymous nucleotide substitutions （G50Tand T1209A） caused changes in amino acids （Gly17Val and Asp403Glu） at signal peptide and the loop ofthe sixth transmembrane domain, respectively. To assess the potential effect of these substitutions on theprotein function, the 3D structure of HKT protein variants was modelled by using PHYRE2 webserver. Theresults showed that no difference was observed when compared those predicted 3D structure of HKTprotein variants with each other. In addition, the codon bias of synonymous substitutions cannot clearlyshow correlation with salt tolerance level. It might be interesting to further investigate the functional roles ofdetected non-synonymous substitutions as it might correlate to salt tolerance in rice.

关键词： polymorphism salt stress OsHKT1 gene rice

Surveillance of dengue and chikungunya infection in Dong Thap,Vietnam:A 13-month study

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Asian Pacific Journal of Tropical Medicine 2016年第1期9卷 36-40页

作者： pham thi Kim Lien Laurence Briant Truong Ba Tang Bui Minh Trang Laurent Gavotte Emmanuel Comillot Vu Trong Duoc Tran nhu Duong Roger Frutos Phan thi Nga National Institute of Hygiene and Epidemiology University of Montpellier Department of Biology Dong Thap General Hospital Cirad TA-A17/GCampus International de Raillarguet

Objective:To establish a surveillance in Dong Thap,at the border with Cambodia by assessing the presence of DHNV serotypes and CHIKV among patients hospitalized at Dong Thap general ***:Cross-sectional descriptive analysis was conducted on a cohort of 131 patients hospitalized with acute fever and symptoms compatible with dengue or *** study was conducted from January 2012 to February *** full clinical picture was established as well as serological and molecular *** analysis was sequentially performed on blood samples collected on admission and an average of seven days after *** detection of IgM antibody to DENV was performed by IgM capture ELTSA and the detection of DENV and CHIKV RNA was done by reverse-transcription multiplex ***:101 patients out of 131(77%) were confirmed with *** four dengue serotypes were detected with a predominance of DENV2 and *** chikungunya infection was detected although reported in neighboring Cambodia.A differential efficiency of serological dengue detection was *** was 29%upon admission and 53%after seven days on the same patients.30 patients out of 131(23%) were negative with both DENV and ***:Dengue is at risk of being underestimated and chikungunya is not systematically *** in detection and surveillance procedures are therefore discussed to increase efficiency of dengue detection and continue the monitoring the emergence of CHIKV in Dong Thap province and in Vietnam.

关键词： Dengue Chikungunya Arbovirus Dong ThapVietnam

Development of a PARCS/Serpent model for neutronics analysis of the Dalat nuclear research reactor

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Nuclear Science and Techniques 2021年第2期32卷 32-44页

作者： Viet-Phu Tran Kien-Cuong Nguyen Donny Hartanto Hoai-Nam Tran Vinh Thanh Tran Van-Khanh Hoang pham nhu Viet Ha Institute for Nuclear Science and Technology(INST) Vietnam Atomic Energy Institute(VINATOM)179 Hoang Quoc Viet str.Cau Giay DistrictHanoi 100000Vietnam Nuclear Research Institute(NRI) Vietnam Atomic Energy Institute(VINATOM)01 Nguyen Tu LucDalatLamdong 670000Vietnam Department of Mechanical and Nuclear Engineering University of SharjahPO.BOX 27272SharjahUnited Arab Emirates Institute of Fundamental and Applied Sciences Duy Tan UniversityHo Chi Minh city 700000Vietnam Faculty of Natural Science Duy Tan UniversityDanang 550000Vietnam Nuclear Safety Division Technical Support Center for Radiation and Nuclear Safety and Emergency ResponseVietnam Agency for Radiation and Nuclear Safety(VARANS)113 Tran Duy Hung str.Cau Giay DistrictHanoi 100000Vietnam

Cross-sectional homogenization for full-core calculations of small and complex reactor configurations,such as research reactors,has been recently recognized as an interesting and challenging *** paper presents the development of a PARCS/Serpent model for the neutronics analysis of a research reactor type TRIGA Mark-II loaded with Russian VVR-M2 fuel(known as the Dalat Nuclear Research Reactor or DNRR).The full-scale DNRR model and a supercell model for a shim/safety rod and its surrounding fuel bundles with the Monte Carlo code Serpent 2 were proposed to generate homogenized fewgroup cross sections for full-core diffusion calculations with *** full-scale DNRR model with Serpent 2 was also utilized as a reference to verify the PARCS/Serpent *** of the effective neutron multiplication factors,radial and axial core power distributions,and control rod worths showed a generally good agreement between PARCS and Serpent *** addition,the discrepancies between the PARCS and Serpent 2 results are also ***,the results indicate the applicability of the PARCS/Serpent model for further steady state and transient analyses of the DNRR.

关键词： PARCS Serpent 2 Group constant DNRR

Improved flood susceptibility mapping using a best first decision tree integrated with ensemble learning techniques

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Geoscience Frontiers 2021年第3期12卷 333-342页

作者： Binh Thai pham Abolfazl Jaafari Tran Van Phong Hoang Phan Hai yen Tran thi Tuyen Vu Van Luong Huu Duy Nguyen Hiep Van Le Loke Kok Foong University of Transport Technology Ha Noi 100000Viet Nam Research Institute of Forests and Rangelands Agricultural ResearchEducation and Extension Organization(AREEO)TehranIran Institute of Geological Sciences Vietnam Academy of Sciences and Technology84 Chua Lang StreetDong daHa NoiViet Nam Department of Geography School of Social EducationVinh UniversityViet Nam Department of Resource and Environment Management School of Agriculture and ResourcesVinh UniversityViet Nam Faculty of Geography VNU University of Science334 Nguyen TraiHa NoiViet Nam Institute of Research and Development Duy Tan UniversityDa Nang 550000Viet Nam Department for Management of Science and Technology Development Ton Duc Thang UniversityHo Chi Minh CityViet Nam Faculty of Civil Engineering Ton Duc Thang UniversityHo Chi Minh CityViet Nam

Improving the accuracy of flood prediction and mapping is crucial for reducing damage resulting from flood *** this study,we proposed and validated three ensemble models based on the Best First Decision Tree(BFT)and the Bagging(Bagging-BFT),Decorate(Bagging-BFT),and Random Subspace(RSS-BFT)ensemble learning techniques for an improved prediction of flood susceptibility in a spatially-explicit manner.A total number of 126 historical flood events from the Nghe An Province(Vietnam)were connected to a set of 10 flood influencing factors(slope,elevation,aspect,curvature,river density,distance from rivers,flow direction,geology,soil,and land use)for generating the training and validation *** models were validated via several performance metrics that demonstrated the capability of all three ensemble models in elucidating the underlying pattern of flood occurrences within the research area and predicting the probability of future flood *** on the Area Under the receiver operating characteristic Curve(AUC),the ensemble Decorate-BFT model that achieved an AUC value of 0.989 was identified as the superior model over the RSS-BFT(AUC=0.982)and Bagging-BFT(AUC=0.967)models.A comparison between the performance of the models and the models previously reported in the literature confirmed that our ensemble models provided a reliable estimate of flood susceptibilities and their resulting susceptibility maps are trustful for flood early warning systems as well as development of mitigation plans.

关键词： Machine learning Ensemble learners Hybrid modeling

A tree-based intelligence ensemble approach for spatial prediction of potential groundwater

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International Journal of Digital Earth 2020年第12期13卷 1408-1429页

作者： Mohammadtaghi Avand Saeid Janizadeh Dieu Tien Bui Viet Hoa pham Phuong Thao T.Ngo Viet-Ha nhu Faculty of Natural Resources and Marine Sciences Tarbiat Modares UniversityTehranIran Geographic Information Science Research Group Ton Duc Thang UniversityHo Chi Minh CityVietnam Faculty of Environment and Labour Safety Ton Duc Thang UniversityHo Chi Minh CityVietnam Ho Chi Minh City Institute of Resources Geography Vietnam Academy of Science and TechnologyHo Chi Minh CityVietnam Institute of Research and Development Duy Tan UniversityDa NangVietnam Department of Geological-Geotechnical Engineering Hanoi University of Mining and GeologyHanoiVietnam

The objective of this research is to propose and confirm a new machine learning approach of Best-First tree(BFtree),AdaBoost(AB),MultiBoosting(MB),and Bagging(Bag)ensembles for potential groundwater mapping and assessing role of influencing *** Yasuj-Dena area(Iran)is selected as a case *** this regard,a Yasuj-Dena database was established with 362 springs locations and 12 groundwater-influencing factors(slope,aspect,elevation,stream power index(SPI),length of slope(LS),topographic wetness index(TWI),topographic position index(TPI),land use,lithology,distance from fault,distance from river,and rainfall).The database was employed to train and validate the proposed groundwater *** area under the curve(AUC)and statistical metrics were employed to check and confirm the quality of the *** result shows that the BFTree-Bag model(AUC=0.810,kappa=0.495)has the highest prediction performance,followed by the BFTree-MB model(AUC=0.785,kappa=0.477),and the BFTree-MB model(AUC=0.745,kappa=0.422).Compared to the benchmark of Random Forests,the BFTree-Bag model performs better;therefore,we conclude that the BFtree-Bag is a new tool should be used for modeling of groundwater potential.

关键词： Environmental modeling groundwater potential GIS ensemble model decision tree

Effects of Serum Concentration, Synchronization Time and Confluence on the Cell-Cycle Synchronization Efficiency of Goat Fibroblasts

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Open Journal of Animal Sciences 2024年第3期14卷 194-203页

作者： Van Khanh Nguyen Huong Thu thi Vu Au thi Hoang yen Kim thi pham Giang thi Thanh Nhan Hung Phu Lai Lan Doan pham Key Laboratory of Animal Cell Biotechnology National Institute of Animal Science Hanoi Vietnam

this study aims to evaluate the effect of serum concentration, synchronization time, and confluence degree on the synchronisation efficiency of goat fibroblast cycle. The results indicated that there was no difference in the percentage of nucleated fibroblasts in the G0/G1 stage between serum concentrations of 0.3% and 0.4% (83.89% and 82.69%, respectively, P > 0.05) as well as between serum concentrations of 0.2% and 0.5% (76.95% and 75.46%, respectively, P > 0.05). The percentage of nucleated fibroblasts in the G0/G1 stage was highest at the concentration of 0.3% and lowest in the control group (83.89% vs. 62.67%, P 0.05). The beneficial effect of high confluence was confirmed by the large percentage of nucleated fibroblasts at the G0/G1 stage. The 60% confluency was significantly lower than the 80% and 100% confluency (73.44%, 86.63%, and 87.17%, respectively, P < 0.05). The results indicate that the goat fibroblast cycle synchronization is the most effective at the serum concentration of 0.3%, 72 hours of synchronization and 100% confluency.

关键词： Goat Fibroblast Cycle Synchronisation Serum Concentration Synchronization Time Confluence

Effects of Foods on Maturity and Spawning Induction Methods on Ovulation of Rice Field Eel Monopterus albus(Zuiew,1793)in Thua thien Hue Province,Vietnam

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Journal of Agricultural Science and Technology(A) 2017年第B10期7卷 85-92页

作者： Tran Vinh Phuong Nguyen Van Khanh pham thi Hai yen Vo Dieu Nguyen Van Huy Institute of Biotechnology Hue UniversityPhu ThuongPhu VangThua Thien Hue 530000Vietnam Faculty of Fisheries University of Agriculture and ForestryHue University102 Phung Hung StreetHue 530000Vietnam

Adult rice field eels with 125.52±27.99 g body weight corresponding to 44.79±5.93 cm in length were maturity cultured in a 5 m^2 cement tank without mud for three months with density 30 eels/m^*** broodstocks were fed with three types of food including:sea fish(T1),commercial pellet food(T2)and mixed food—50%sea fish and 50%commercial pellet food(T3).Result showed that the maximum gonadosomatic index(GSI)of female eels fed by sea fish(2.89%±0.67%)was higher than both commercial pellet food(1.62%±0.62%)and mixed food(2.03%±0.82%)(P0.05).Maturity rate of female fed by sea fish(88.91%±9.64%)was higher than commercial pellet food(61.12%±9.64%)(P0.05).*** eels were induced for spawning with two kinds of hormones,including T1:human chorionic ganadotropin(HCG)at 1,500 IU/kg,T2:luteinzing hormone-releasing hormone(LHRH-a)at 150μg/kg and domperidon 10 mg/kg,and T3:control without *** results of spawning induction methods showed that the reproduction rate of female eels induced by LHRH-a and HCG hormones were higher than that by natural reproduction method(P<0.05).Others,the survival rate of fry eels after 5 d using natural reproduction method(92.65%±2.54%)was higher than both using LHRH-a(67.77%±1.91%)and HCG(68.65%±1.23%)hormones(P<0.05).The average diameter of eggs was 3.40-3.41 mm and the length of newly hatched eels was 1.72±0.19 cm.

关键词： Food maturity culture ovulation spawing induction method rice field eel