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Antidiabetic and antioxidant activities of red seaweed Laurencia dendroidea

Asian Pacific Journal of Tropical Biomedicine 2019年第12期9卷 501-509页

作者： The Han nguyen thi Huyen nguyen Van Minh nguyen thi lan phuong nguyen thi Van Anh Tran Anh Duy Do Sang Moo Kim Faculty of Food Technology Nha Trang University02 Nguyen Dinh Chieu StreetNha Trang CityKhanh HoaVietnam Quality Control Department Institute of Vaccines and Medical BiologicalsNha Trang CityKhanh HoaVietnam Faculty of Pharmacy University of Medicine and Pharmacy of Ho Chi Minh City41 Dinh Tien Hoang StreetHo Chi Minh CityVietnam Research Department of Marine Conservation Research Institute for Marine Fisheries224 Le Lai StreetHai Phong CityVietnam Department of Marine Food Science and Technology Gangneung-Wonju National University7 Jukheon-gilGangneung 25457Republic of Korea

Objective:To investigate antidiabetic and antioxidant activities of the extract and fractions from Vietnamese red seaweed Laurencia ***:The seaweed Laurencia dendroidea was extracted by using microwave-assisted extraction method in 80%*** seaweed extract was then fractionated using different solvents(n-hexane,chloroform,ethyl acetate,butanol and water).These obtained fractions were evaluated forα-glucosidase inhibitory and antioxidant *** activities were tested using DPPH,nitric oxide radical scavenging and metal chelating *** enzyme inhibition mode was determined using Lineweaver-Burk *** acidic and thermal stabilities,the ethyl acetate fraction was treated at pH 2.0 and 100℃,*** residual inhibitory activity of the fraction was calculated based on the initial inhibitory *** in vivo antidiabetic activity,mice were divided into four groups,including normal control,diabetic control,diabetic mice treated with ethyl acetate fraction and diabetic mice treated with *** glucose level of treated mice during acute and prolonged treatments was *** evaluate the toxicity of the ethyl acetate fraction,the body weight changes and activities of liver function enzymes(aspartate transaminase,alanine transaminase and gammaglutamyl transferase)were carried ***:The extract of Laurencia dendroidea showed strongα-glucosidase inhibitory and DPPH radical scavenging *** concentrations affected bothα-glucosidase inhibitory and antioxidant activities.A 80%aqueous methanol was the suitable solvent for extraction of enzyme inhibitors and *** solvent fractions,ethyl acetate fraction had the highest inhibitory activities againstα-glucosidase with a mixed type of inhibition and the strongest antioxidant activities,and was stable under acidic and thermal *** ethyl acetate fraction treated diabetic mice significantly reduced blood glucose level compare

关键词： α-Glucosidase inhibitor Antidiabetic Antioxidant Red seaweeds Vietnam

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ON A NONLINEAR VOLTERRA-HAMMERSTEIN INTEGRAL EQUATION IN TWO VARIABLES

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Acta Mathematica Scientia 2013年第2期33卷 484-494页

作者： Le thi phuong Ngoc nguyen Thanh Long Nhatrang Educational College 01 Nguyen Chanh Str.Nhatrang CityVietnam Department of Mathematics and Computer Science University of Natural ScienceVietnam National University Ho Chi Minh City227 Nguyen Van Cu Str.Dist. 5Ho Chi Minh CityVietnam

Using a fixed point theorem of Krasnosel＇skii type, this article proves the exis- tence of asymptotically stable solutions for a Volterra-Hammerstein integral equation in two variables.

关键词： Volterra-Hamnmrstein integral equation in two variables the fixed point theo-rem of Krasnosel'skii type contraction mapping completely continuous asymp-totically stable solution

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The impact of plasmonic Ag−Au bimetallic nanoparticles on photocurrent enhancement in GaN-based photodetectors

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Journal of Semiconductors 2024年第12期45卷 72-78页

作者： thi Kim Oanh Vu thi Thu phuong Bui Ngoc Anh nguyen thi Thanh Bao nguyen thi Minh Hien nguyen Eun Kyu Kim No.10 Dao Tan Institute of PhysicsVietnam Academy of Science and TechnologyNo.10 Dao TanHanoi 118000Vietnam Graduate University of Science and Technology Vietnam Academy of Science and Technology18 Hoang Quoc VietHanoi 122300Vietnam Department of Physics and Research Institute for Natural Sciences Hanyang UniversitySeoul 04763Republic of Korea

Recently,there has been considerable interest in high-efficiency ultraviolet(UV)photodetectors for their potential practical *** this study,a high-quality UV photodetector was fabricated using a combination of Ag and Au NPs with GaN *** GaN film was deposited using sputtering technique,whereas Ag and Au films were grown using thermal evaporation ***-Au bimetallic nanoparticles were formed by treating them at the various annealing temperature to improve the interaction between light and the photoactive layers of the *** optimal annealing temperature to achieve the best performance of a photodetector is 650℃.this led to a photoresponsivity of 98.5 A/W and the ON/OFF ratio of 705 at low bias voltage of 1 *** work establishes the foundation for the advancement of high-performance UV photodetectors.

关键词： UV photodetectors GaN Ag-Au bimetallic nanoparticles plasmonic effect

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Fuzzy MCDM Model for Selection of Infectious Waste Management Contractors

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Computers, Materials & Continua 2022年第8期72卷 2191-2202页

作者： nguyen Van Thanh nguyen Hoang Hai nguyen thi Kim lan Faculty of Commerce Van Lang UniversityHo Chi Minh CityVietnam International Education Institute Van Lang UniversityHo Chi Minh CityVietnam

Healthcare supply chains are under pressure to drive down costs because of digital business,shifting customer needs and new *** waste generated from medical facilities includes medical activities and daily-life activities of patients and their family *** to statistics of the Department of Health EnvironmentalManagement,Vietnam currently has more than 13,500 medical facilities,including hospitals from central to provincial and district levels and private hospitals and medical *** medicine generates about 590 tons of medical waste/day and is estimated to be about 800 tons/*** waste includes ordinary medical waste and hazardous medical waste;in which ordinary medical waste accounts for about 80%–90%,only about 10%–20%is hazardous medical waste including infectious waste and non-infectious hazardous *** is an environmental and occupational health issue that needs attention in developing countries like *** large amounts of medical waste to ensure environmental and personal hygiene,doing so inefficiently creates potential hazards to the environment and increases operating ***,hospitals lack objective criteria and methods to evaluate and select the most optimal infectious medical waste,relying instead on their own subjective assessment and prior ***,the author proposed a fuzzy multicriteria decision making(MCDM)model including Fuzzy Analytic hierarchy process(FAHP)and the Weighted Aggregated Sum-Product Assessment(WASPAS)for infectious medical waste contractors’selection in this *** proposed Fuzzy MCDM method is in-tended to provide a more efficient,accurate method in the selection of infectious medical waste contractors than subjective assessment methods,thus reduce potential risks to *** results of this study can be applied to evaluate and select contractors in other industries.

关键词： MCDM model fuzzy theory fuzzy AHP WASPAS medical waste contractors

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Successful containment of a COVID-19 outbreak in Bach Mai Hospital by prompt and decisive responses

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Asian Pacific Journal of Tropical Medicine 2021年第5期14卷 234-235页

作者： Van Minh Hoang thi phuong Thao Tran thi Ngoc phuong nguyen thi Hai Yen nguyen Quang Tuan nguyen Hanoi University of Public Health HanoiVietnam Bach Mai Hospital HanoiVietnam

In low-and middle-income countries,tertiary care hospitals frequently face an extremely heavy workload and shoulder an even heavier burden during the COVID-19 *** Mai Hospital(BMH),one of the leading tertiary hospitals in Vietnam,is on the frontline in the fierce battle against *** letter aims to describe how BMH tackles the COVID-19 outbreak in the hospitallevel battle,which could support policymakers in time-management and well-preparation for this unpredictable pandemic.

关键词： prompt income policy

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Morphology and kinematics of the gas envelope of the Mira binary W Aquilae

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Research in Astronomy and Astrophysics 2016年第7期16卷 47-54页

作者： Do thi Hoai Pham Tuyet Nhung Pham Ngoc Diep nguyen thi phuong Pham Tuan-Anh nguyen thi Thao Pierre Darriulat Department of Astrophysics Vietnam National Satellite CenterVAST

We analyse ALMA observations of the12CO（3-2） emission of the circumstellar envelope（CSE）of the Mira variable binary star W Aql. These provide, for the first time, spatially resolved Doppler velocity spectra of the CSE up to angular distances to the central star ofy nature of the observations（only five minutes in each of～5′′（meaning some 2000 AU）. The explorator two different configurations） does not allow for a detailed modelling of the properties of the CSE but provides important qualitative information on its morphology and kinematics. Emission is found to be enhanced along an axis moving from east/west to north-east/south-west when the angular distance from the central star projected on the plane of the sky increases from zero to four arcseconds. In parallel, the Doppler velocity distribution displays asymmetry along an axis moving from east/west to north-west/south-east. The results are discussed in the context of earlier observations, in particular of the dust morphology.

关键词： stars AGB and post-AGB (stars ) circumstellar matter stars individual(W Aql) stars mass-loss radio lines stars

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^(12)CO emission from the Red Rectangle

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Research in Astronomy and Astrophysics 2015年第12期15卷 2213-2228页

作者： Pham Tuan Anh Pham Ngoc Diep Do thi Hoai Pham Tuyet Nhung nguyen thi phuong nguyen thi Thao Pierre Darriulat Department of Astrophysics Vietnam National Satellite CenterVAST

Observations of an unprecedented quality made by ALMA on the Red Rectangle of CO（3-2） and CO（6-5） emissions are analysed jointly with the aim of obtaining as simple as possible a description of the gas morphology and kinematics. Evidence is found for polar conical outflows and for a broad equatorial torus in rotation and expansion. Simple models of both are proposed. Comparing CO（6-5） and CO（3-2） emissions provides evidence for a strong temperature enhancement over the polar outflows. Continuum emission （dust） is seen to be enhanced in the equatorial region. Observed asymmetries are briefly discussed.

关键词： stars: AGB and post-AGB -- circumstellar matter -- radio-lines: stars-- planetary nebulae: individual (Red Rectangle)

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Evaluation of Weathering Performance of Rosin-Copper Based Treated Wood

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Journal of Renewable Materials 2022年第11期10卷 2765-2780页

作者： thi Thanh Hien nguyen Nho Quyet Tran thi Minh Nguyet nguyen Hien Mai Trinh Xuan phuong Le Trong Kien nguyen College of Wood Industry and Interior Design Vietnam National University of ForestryHa NoiViet Nam College of Economics and Management Northeast Forestry UniversityHarbinChina

this study aimed to evaluate the effect of natural weathering on some surface characteristics and mechanical properties of Styrax wood treated with mixtures of 1.0%,2.0%,or 4.0%rosin sizing agent and 3%copper *** samples after treatment were exposed to outdoor conditions for one year and changes in color,glossiness,weight loss,compression strength parallel to grain(CSPG),modulus of rupture(MOR),and modulus of elasticity(MOE)were investigated after 6 and 12-month of natural *** results showed that rosin-copper treatment could improve color stability and gloss of samples after *** losses of all rosin-copper treated samples after 12 months of exposure were negligible compared with the untreated control *** addition,rosin-copper treatment enhanced the CSPG compared to untreated controls,but slightly decreased the MOR and MOE of Styrax wood before *** weathering factors induced a reduction for all strength properties,however,the decrease rate for strength properties of rosin-copper treated samples was negligible compared with the untreated control samples after 12-month natural weathering *** FTIR and SEM-EDX confirmed that the use of the rosin-copper formulations to impregnate wood could decrease the hazard of the copper preservative leaching into the environment,while also enhancing more resistance against weathering factors and other biotic factors.

关键词： Rosin-copper weathering color stability CSPG MOR MOE

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Morphology and kinematics of the gas envelope of the variable AGB star π^1 Gruis

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Research in Astronomy and Astrophysics 2016年第7期16卷 97-104页

作者： Pham Tuyet Nhung Do thi Hoai Pham Ngoc Diep nguyen thi phuong nguyen thi Thao Pham Tuan Anh Pierre Darriulat Department of Astrophysics Vietnam National Satellite CenterVAST

Observations of the ^12CO（3–2） emission from the circumstellar envelope（CSE） of the variable star π1Gru using the compact array of the ALMA observatory have been recently made accessible to the public. An analysis of the morphology and kinematics of the CSE is presented with a result very similar to that obtained earlier for ^12CO（2–1） emission using the Submillimeter Array. A quantitative comparison is made using their flared disk model. A new model is presented that provides a significantly better description of the data, using radial winds and smooth evolutions of the radio emission and wind velocity from the stellar equator to the poles.

关键词： stars AGB and post-AGB circumstellar matter star individual(π1Gru) stars massloss radio lines stars

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Ardisia gigantifolia ethanolic extract inhibits cell proliferation and targets cancer stem cells in gastric cancer

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Asian Pacific Journal of Tropical Biomedicine 2023年第6期13卷 258-267页

作者： thi Thanh Huong Le Phu Hung nguyen Van phuong nguyen Thy Ngoc nguyen Faculty of Biotechnology TNU-University of SciencesThai NguyenVietnam Department of Life Science University of Science and Technology of HanoiVietnam Academy of Science and TechnologyHanoiVietnam

Objective:To evaluate the effects of ethanol extract from Ardisia gigantifolia leaves on cell proliferation and cancer stem cell(CSC)number in gastric ***:The inhibitory effect of Ardisia gigantifolia extract on the proliferation of MKN45 and MKN74 gastric cancer cells was assessed using 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide ***-adherent culture(3D)model was used to evaluate the effect of the extract on tumorsphere size and ***,the expression of CD44,ALDH,and p21 was determined by immunofluorescence *** cytometric analysis was performed to evaluate cell cycle arrest and the expression of gastric CSC markers CD44 and ***-time PCR analysis was also carried out to assess the effect of the extract on the expression of cell cycle-regulated ***:Ardisia gigantifolia extract effectively inhibited cell proliferation with an IC_(50)of 55.7μg/m L in MKN45 cells and 123.6μg/m L in MKN74 *** extract also arrested cell cycle in the G_(0)/G_(1)phase as well as significantly reduced the size and number of *** markedly increased expression of p21 was observed at both m RNA and protein levels in the extract-treated adherent cells and *** addition,Ardisia gigantifolia extract significantly reduced the number of CD44-and/or ALDH-expressing gastric ***:The development of gastric CSC can be inhibited by the ethanol extract of Ardisia gigantifolia.

关键词： Ardisia gigantifolia Gastric cancer Cancer stem cell markers CD44 ALDH

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