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The COVID-19 pandemic in the ASEAN: A preliminary report on the spread, burden and medical capacities

Asian Pacific Journal of Tropical Medicine 2020年第6期13卷 247-251页

作者： Minh Van Hoang Phuong thi Ngoc nguyen thao thi Phuong tran Long Quynh Khuong An thi Minh Dao Huy Van nguyen Riyanti Djalante Hanh thi Tuyet tran Hanoi University of Public Health HanoiVietnam Hanoi Medical University HanoiVietnam Graduate School of Public Health St.Luke's International UniversityTokyoJapan United Nations University-Institute for the Advanced Study of Sustainability(UNU-IAS) TokyoJapan

Objective:To provide preliminary descriptions of the spread,burden and related medical capacity characteristics of the ASEAN ***:We utilized the data from four main official databases,including WHO reports,the Statistics and Research of the Coronavirus Disease,and the Southeast Asia Program of the Center for Strategic and International *** spread of the COVID-19 pandemic,current burden and the COVID-19 medical response capacities were extracted before April 11,***:As of April 13,2020,the ASEAN countries reported19547 COVID-19 positive cases with 817 deaths(case-facility rate of 4.2%).Thailand was the first country in the region that reported having the COVID-19 cases,while Laos was the last to report confirmed COVID-19 *** for the number of deaths to double were between 8-12 *** the testing and treatment capacities,the number of PCR tests provided to the populations was the highest in Vietnam,followed by Singapore,Malaysia,and ***,the percentage of the population being tested was the highest in Brunei(2.31%),followed by Singapore(1.30%).Conclusions:A wide range of interventions were taken into practice in response to the outbreak with an effort of curbing the rise of this ***,special care should not be overlooked as the pandemic is placing a huge impact on the population and becomes increasingly *** tackle the spread of the pandemic in the region,the ASEAN countries should work together as one community to provide better responses to future pandemics and other transboundary public health challenges.

关键词： COVID-19 SARS-CoV-2 ASEAN South-East Asia Epidemiology

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Successful containment of a COVID-19 outbreak in Bach Mai Hospital by prompt and decisive responses

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Asian Pacific Journal of Tropical Medicine 2021年第5期14卷 234-235页

作者： Van Minh Hoang thi Phuong thao tran thi Ngoc Phuong nguyen thi Hai Yen nguyen Quang Tuan nguyen Hanoi University of Public Health HanoiVietnam Bach Mai Hospital HanoiVietnam

In low-and middle-income countries,tertiary care hospitals frequently face an extremely heavy workload and shoulder an even heavier burden during the COVID-19 *** Mai Hospital(BMH),one of the leading tertiary hospitals in Vietnam,is on the frontline in the fierce battle against *** letter aims to describe how BMH tackles the COVID-19 outbreak in the hospitallevel battle,which could support policymakers in time-management and well-preparation for this unpredictable pandemic.

关键词： prompt income policy

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Optimization Agricultural Supply Chain:A Case Study of Fertilizer Supplier Selection

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Computers, Materials & Continua 2022年第8期72卷 4057-4068页

作者： nguyen Van Thanh nguyen thi Kim Lan Syed Tam Husain nguyen Hoang Hai nguyen Viet Tinh Faculty of Commerce Van Lang UniversityHo Chi Minh CityVietnam International Education Institute Van Lang UniversityHo Chi Minh CityVietnam

The 21st century is associated with the IndustrialRevolution 4.0 and the organic agriculture trend,making the utilization of high-quality fertilizers,abundant nutritional content,economical,and no affect to environment *** to the new concept,clean agricultural production and organic agricultural products are not allowed to excessively use synthetic chemicals such as chemical fertilizers,and plant protection drugs,but priority is to use manure,organic fertilizers,and natural mineral *** must meet the balanced nutritional requirements of crops,maintain,and improve the fertility of the ground,protect the surrounding ecosystem,and leave harmful effects in agricultural products,products with high quality,safe for users and high economic efficiency for *** achieve the above goal,the selection of a fertilizer supplier is an important decision,supporting the supply chain’s sustainable development,fertilizer supplier selection is a multicriteria decision making model,the decision maker must assess all qualitative and quantitative *** this paper,the author proposed an integer decision making model including Fuzzy Analytic Hierarchy Process(FAHP)and Complex Proportional Assessment of Alternatives(COPRAS)for fertilizer supplier *** weightings of the criteria are calculated by using FAHP,COPRAS is then applied for ranking some potential fertilizer *** efficiency of the proposed models is proved by a case study conducted in a farm located in the south of *** research is the first fertilizer supplier evaluation and se-lection model in Vietnam by interviewing experts and reviewing the ***-search result is to provide a case study on evaluating supplier in agricultural supply chain utilizing the model proposed by the combination of FAHP and COPRAS models.

关键词： Fertilizer industry optimization model fuzzy theory agricultural supply chain

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In vivo anticancer activity of maesopsin 4—O— β—glucoside isolated from leaves of Artocarpus tonkinensis *** Gagnep

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Asian Pacific Journal of Tropical Medicine 2016年第4期9卷 343-348页

作者： Trinh thi Thuy Dao Duc thien tran Quang Hung nguyen Thanh Tam nguyen thi Hoang Anh nguyen thi Nga nguyen thi Cuc Le Phuong Mai tran Van Sung Domenico V.Delfino Do thi thao Institute of Chemistry.Vietnam Academy of Science and Technology Institute of Biotechnology Vietnam Academy of Science and Technology National Research Council Canada Measurement Science and Standards1200 Montreal RoadBuilding M-12.Ottatca.Ontario KIA OR6 Department of Medicine University of PerugiaPiazzale Gambuli.S.Andrea delle Fratte

Objective:To investigate the antitumor effect of maesopsin 4-O-β-glucoside(TAT2) isolated from the leaves of Artocarpus tonkinensis(***) *** ***:The antitumor activity of TAT2 was evaluated in Lewis lung carcinoma(LLC) tumor-bearing ***/c mice had tumors induced by implantation with 2× 10~6 LLC cells into the subcutaneous right posterior ***-bearing mice were treated orally with a range of doses of TAT2 and a standard drug,*** were observed for tumor growth and mortality *** was collected to determine hematological and biochemical *** TAT2 was isolated from an ethanolic extract of *** *** structure was determined by MS and NMR spectroscopy,and identified as *** compound did not show acute toxicity at the highest dose tested(2 OIK) mg/kg body weight).TAT2 exhibited antitumor activity by decreasing tumor growth,increasing the survival rale,and ameliorating some hematological and biochemical parameters at doses of 100 and 200 mg/kg body weight(P<0.05).Conclusions:These results indicate that TAT2 possesses clear antitumor *** to its bioavailability and low toxicity,and the fact that it could be isolated in a large scale from *** leaves,the compound shows promise as a potential anticancer drug.

关键词： Artocarpus tonkinensis BALB/c Hematological parameters Lewis lung carcinoma Maesopsin 4-0-β-glucoside

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Evaluation of five gridded rainfall datasets in simulating streamflow in the upper Dong Nai river basin,Vietnam

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International Journal of Digital Earth 2019年第3期12卷 311-327页

作者： Pham thi thao Nhi Dao nguyen Khoi nguyen Xuan Hoan Institute of Research and Development Duy Tan UniversityDa NangVietnam Institute for Computational Science and Technology Tan Hiep Chanh WardDistrict 12Ho Chi Minh CityVietnam Faculty of Environment University of ScienceVietnam National University Ho Chi Minh City227 Nguyen Van Cu StreetDistrict 5Ho Chi Minh CityVietnam Ho Chi Minh City University of Food Industry 140 Le Trong Tan StreetTan Phu DistrictHo Chi Minh CityVietnam

Rainfall data with an appropriate spatial resolution is a key input to hydrological ***,networks of rain gauges are often sparsely and unevenly distributed in large catchments,especially in developing ***-resolution rainfall datasets,such as the Asian Precipitation Highly Resolved Observational Data Integration Towards Evaluation of Water Resources(APHRODITE),the Climate Forecast System Reanalysis(CFSR),the Climatic Research Unit Time Series(CRUTS),the Global Precipitation Climatology Centre(GPCC)and the Tropical Rainfall Measuring Mission(TRMM),have become available to overcome such *** objective of this study was to evaluate the impacts of four land-based rainfall products(APHRODITE,CFSR,CRU-TS,and GPCC)and a satellite-based rainfall product(TRMM)on streamflow of the upper catchment of Tri An reservoir in Vietnam using the Hydrological Modeling System(HEC-HMS).In addition,the available rain gauges data were used for comparison *** indicates that the TRMM and GPCC data show their best match to rain gauges data in simulating the streamflow in the period 1999–***,the results indicate that the TRMM and GPCC data could be alternative solutions.

关键词： APHRODITE CFSR CRU-TS GPCC TRMM rainfall streamflow HEC-HMS model

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Integrating the valence theory and the norm activation theory to understand consumers’ e-waste recycling intention

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Chinese Journal of Population,Resources and Environment 2023年第1期21卷 26-36页

作者： Hong thi Thu nguyen University of Science and Education The University of DanangLe Duan RoadDanang 550000Vietnam

Electrical and electronic waste(e-waste)is a growing challenge,matching the widespread boom in the use of information and communication *** to an alarming increasing amount of e-waste,a low rate of consumer engagement in ensuring the proper disposal of such materials intensifies the pressure on the exist‐ing e-waste *** deal with this thorny problem,it is of great interest to grasp consumers’disposal and re‐cycling behavioral ***,this study attempts to understand complementary perspectives around consumers’e-waste recycling intention based on the integration of the valence theory and the norm activation *** data mining models using classification and prediction-based algorithms,namely Chi squared automatic interaction detector(CHAID),Neural network,Discriminant analysis,and Quick,unbiased,efficient statistical tree(QUEST),were employed to analyze a set of the 398 data collected in *** re‐sults revealed that the social support value is by far the most critical predictor,followed by the utilitarian value,task difficulty,and monetary *** is also noteworthy that the awareness of consequences,education background,the ascription of responsibility,and age were also ranked as critical affecting *** lowest influential predictors found in this study were income and *** addition,a comparison was made in terms of the classification performance of the four utilized data mining *** on several evalua‐tion measurements(confusion matrix,accuracy,precision,recall,specificity,F-measure,ROC curve,and AUC),the aggregated results suggested that CHAID and Neural network performed the *** findings of this research are expected to assist policymakers and future researchers in updating all information surround‐ing consumer behavioral intention-related topics focusing on ***,the adoption of data min‐ing algorithms for prediction is another insight of this study,which may shed the light o

关键词： CHAID Discriminant analysis E-waste recycling intention Neural network Norm activation theory QUEST Sustainable development goals Valence theory

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Classification and morphology of circulating haemocytes in the razor clam Sinonovacula constricta

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Aquaculture and Fisheries 2022年第1期7卷 52-58页

作者： Dang Hai nguyen Donghong Niu Zhiyi Chen Maoxiao Peng Nga thi tran Jiale Li Key Laboratory of Genetic Resources for Freshwater Aquaculture and Fisheries Shanghai Ocean UniversityMinistry of AgricultureShanghai201306China Research Institute for Aquaculture No.1 Dinh BangTu SonBac NinhViet Nam

The razor clam Sinonovacula constricta is widely distributed in the intertidal zones and estuarine waters along the coast of western Pacific Ocean and is extensively *** though haemocytes are known to play an important role in the immune mechanisms of bivalves,these cells are poorly studied in *** researched the morphology and immunological activities of haemocytes in *** using light and electron microscopy and flow *** major subpopulations of haemocytes were identified in the haemolymph:granulocytes,semigranulocytes,and *** subpopulations were divided using flow cytometry,but not ***,the flow cytometry findings were combined with the light and electron microscopy findings,as well as Percoll density-gradient centrifugation findings,to classify and distinguish between the cell types more *** combined findings showed that granulocytes was larger cells,while semigranulocytes was smaller and more ***,granulocytes had numerous granules in the cytoplasm,semigranulocytes contained fewer and smaller granules,and hyalinocytes was smaller and less abundant with no or a few *** granulocytes and semigranulocytes had greater phagocytotic activity and a higher lysosomal content than *** results declared that granulocytes and semigranulocytes were the main haemocytes involved in the cellular defence mechanism in ***.

关键词： Sinonovacula constricta Immune response Haemocytes Flow cytometry

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Ardisia gigantifolia ethanolic extract inhibits cell proliferation and targets cancer stem cells in gastric cancer

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Asian Pacific Journal of Tropical Biomedicine 2023年第6期13卷 258-267页

作者： thi Thanh Huong Le Phu Hung nguyen Van Phuong nguyen Thy Ngoc nguyen Faculty of Biotechnology TNU-University of SciencesThai NguyenVietnam Department of Life Science University of Science and Technology of HanoiVietnam Academy of Science and TechnologyHanoiVietnam

Objective:To evaluate the effects of ethanol extract from Ardisia gigantifolia leaves on cell proliferation and cancer stem cell(CSC)number in gastric ***:The inhibitory effect of Ardisia gigantifolia extract on the proliferation of MKN45 and MKN74 gastric cancer cells was assessed using 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide ***-adherent culture(3D)model was used to evaluate the effect of the extract on tumorsphere size and ***,the expression of CD44,ALDH,and p21 was determined by immunofluorescence *** cytometric analysis was performed to evaluate cell cycle arrest and the expression of gastric CSC markers CD44 and ***-time PCR analysis was also carried out to assess the effect of the extract on the expression of cell cycle-regulated ***:Ardisia gigantifolia extract effectively inhibited cell proliferation with an IC_(50)of 55.7μg/m L in MKN45 cells and 123.6μg/m L in MKN74 *** extract also arrested cell cycle in the G_(0)/G_(1)phase as well as significantly reduced the size and number of *** markedly increased expression of p21 was observed at both m RNA and protein levels in the extract-treated adherent cells and *** addition,Ardisia gigantifolia extract significantly reduced the number of CD44-and/or ALDH-expressing gastric ***:The development of gastric CSC can be inhibited by the ethanol extract of Ardisia gigantifolia.

关键词： Ardisia gigantifolia Gastric cancer Cancer stem cell markers CD44 ALDH

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A study implementing real-time PCR to identify Strongyloides species of third-stage larvae in human stool samples from Southern Vietnam

Infectious Medicine

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Infectious Medicine 2023年第3期2卷 229-236页

作者： Le Duc Vinh nguyen Kim Thach Huynh Hong Quang Do Nhu Binh tran thi Duc Hanh nguyen Minh Toàn nguyen Trung Tuyen nguyen Thu Huong Department of Medical Parasitology Pham Ngoc Thach University of MedicineHo Chi Minh City 700000Vietnam Department of Fundamental Chemistry-Biochemistry Pham Ngoc Thach University of MedicineHo Chi Minh City 700000Vietnam Clinical Epidemiology Research Unit Institute of MalariologyParasitologyand Entomology Quy NhonBinh Dinh 55000Vietnam Department of Infectious Disease Military Hospital 103Hanoi 100000Vietnam Department of Epidemiology Hanoi University of Public HealthHanoi 100000Vietnam Department of Microbiology-Parasitology Hanoi University of Public HealthHanoi 100000Vietnam Department of Medicine University of Medicine and PharmacyVietnam National UniversityHanoi100000 Vietnam

Background:Strongyloidiasis,a neglected disease caused by intestinal nematodes of the genus,is endemic to tropical and subtropical areas such as *** methods only identify the genus,while DNA-molecular techniques are susceptible in Strongyloides *** study aims to determine the prevalence of dominant Strongyloides species among the population in Duc Hoa district,Long An,***:A cross-sectional study used 1190 stool specimens collected from July 2017 to November *** samples were transported within 2 h,stored at 2-8℃,and processed within 48 h for microscopy smear and culture at the Laboratory of Medical Parasitology,Pham Ngoc Thach University of Medicine(PNT).Then all positive samples with the above 2 methods were verified by real-time PCR ***-time PCR amplification was conducted at the Laboratory of Molecular Biology,***:Direct microscopy and modified Harada-Mori culture detected Strongyloides *** in 79/1190 sam-ples(6.6%).About 94.2%of the DNA samples were Strongyloides stercoralis,2.9%were co-infections with Strongy-loides ratti and ***,and 2.9%were patients with *** identity of 12/14 sequences was confirmed as *** with a high level of similarity(91.3%-100%)and over 98%for ***:DNA-molecular techniques and sequence analysis are highly suitable for identifying Strongyloides species isolated from stool *** is remarkable evidence of the presence of zoonosis *** disease in human,not just the known *** is likely to result in a certain proportion of people being infected by this animal-borne infectious pathogen.

关键词： Strongyloidiasis Strongyloides stercoralis Strongyloides ratti DNA-molecular techniques

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Novel Time Series Bagging Based Hybrid Models for Predicting Historical Water Levels in the Mekong Delta Region, Vietnam

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Computer Modeling in Engineering & Sciences 2022年第6期131卷 1431-1449页

作者： nguyen Thanh Hoan nguyen Van Dung Ho Le Thu Hoa Thuy Quynh Nadhir Al-Ansari tran Van Phong Phan Trong Trinh Dam Duc nguyen Hiep Van Le Hanh Bich thi nguyen Mahdis Amiri Indra Prakash Binh Thai Pham Institute of Geography Vietnam Academy of Science and TechnologyHanoi10000Viet Nam Department of Civil Environmental and Natural Resources EngineeringLulea University of TechnologyLulea97187Sweden Institute of Geological Sciences Vietnam Academy of Science and Technology(VAST)Dong DaHanoi10000Viet Nam University of transport Technology Thanh XuanHa Noi10000Viet Nam Department of Watershed&Arid Zone Management Gorgan University of Agricultural Sciences&Natural ResourcesGorgan***Iran DDG(R)Geological Survey of India Gandhinagar382010India

Water level predictions in the river,lake and delta play an important role in flood *** year Mekong River delta of Vietnam is experiencing flood due to heavy monsoon rains and high *** subsidence may also aggravate flooding problems in this ***,accurate predictions of water levels in this region are very important to forewarn the people and authorities for taking timely adequate remedial measures to prevent losses of life and *** are so many methods available to predict the water levels based on historical data but nowadays Machine Learning(ML)methods are considered the best tool for accurate *** this study,we have used surface water level data of 18 water level measurement stations of the Mekong River delta from 2000 to 2018 to build novel time-series Bagging based hybrid ML models namely:Bagging(RF),Bagging(SOM)and Bagging(M5P)to predict historical water levels in the study *** of the Bagging-based hybrid models were compared with Reduced Error Pruning Trees(REPT),which is a benchmark ML *** data of 19 years period was divided into 70:30 ratio for the *** data of the period 1/2000 to 5/2013(which is about 70%of total data)was used for the training and for the period 5/2013 to 12/2018(which is about 30%of total data)was used for testing(validating)the *** of the models was evaluated using standard statistical measures:Coefficient of Determination(R2),Root Mean Square Error(RMSE)and Mean Absolute Error(MAE).Results show that the performance of all the developed models is good(R2>0.9)for the prediction of water levels in the study ***,the Bagging-based hybrid models are slightly better than another model such as ***,these Bagging-based hybrid time series models can be used for predicting water levels at Mekong data.

关键词： Computational techniques bagging water level time series algorithms

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