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The COVID-19 pandemic in the ASEAN: A preliminary report on the spread, burden and medical capacities

Asian Pacific Journal of Tropical Medicine 2020年第6期13卷 247-251页

作者： Minh Van Hoang phuong thi Ngoc Nguyen thao thi phuong tran Long Quynh Khuong An thi Minh Dao Huy Van Nguyen Riyanti Djalante Hanh thi Tuyet tran Hanoi University of Public Health HanoiVietnam Hanoi Medical University HanoiVietnam Graduate School of Public Health St.Luke's International UniversityTokyoJapan United Nations University-Institute for the Advanced Study of Sustainability(UNU-IAS) TokyoJapan

Objective:To provide preliminary descriptions of the spread,burden and related medical capacity characteristics of the ASEAN ***:We utilized the data from four main official databases,including WHO reports,the Statistics and Research of the Coronavirus Disease,and the Southeast Asia Program of the Center for Strategic and International *** spread of the COVID-19 pandemic,current burden and the COVID-19 medical response capacities were extracted before April 11,***:As of April 13,2020,the ASEAN countries reported19547 COVID-19 positive cases with 817 deaths(case-facility rate of 4.2%).Thailand was the first country in the region that reported having the COVID-19 cases,while Laos was the last to report confirmed COVID-19 *** for the number of deaths to double were between 8-12 *** the testing and treatment capacities,the number of PCR tests provided to the populations was the highest in Vietnam,followed by Singapore,Malaysia,and ***,the percentage of the population being tested was the highest in Brunei(2.31%),followed by Singapore(1.30%).Conclusions:A wide range of interventions were taken into practice in response to the outbreak with an effort of curbing the rise of this ***,special care should not be overlooked as the pandemic is placing a huge impact on the population and becomes increasingly *** tackle the spread of the pandemic in the region,the ASEAN countries should work together as one community to provide better responses to future pandemics and other transboundary public health challenges.

关键词： COVID-19 SARS-CoV-2 ASEAN South-East Asia Epidemiology

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Synthesis and characterization of NaYF4:Yb3+,Er3+@silica-N=folic acid nanocomplex for bioimaginable detecting MCF-7 breast cancer cells

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Journal of Rare Earths 2019年第11期37卷 1183-1187页

作者： Ha thi phuong tran Thu Huong Le thi Vinh Hoang thi Khuyen Do thi thao Nguyen Thanh Huong Pham thi Lien Le Quoc Minh Institute of Materials Science Vietnam Academy of Science and Technology18 Hoang Quoc VietCau GiayHanoiViet Nam Graduate University of Science and Technology-Vietnam Academy of Science and Technology 18 Hoang Quoc VietCau GiayHanoiViet Nam Department of Chemistry Hanoi Medical University1-Ton That TungDong DaHanoiViet Nam Department of Chemistry Hanoi University of Mining and Geology18-Pho LienBac Tu LiemHanoiViet Nam Institute of Biotechnology Vietnam Academy of Science and Technology18-Hoang Quoc VietCau GiayHanoiViet Nam Duy Tan University K7/25 Quang TrungDa NangViet Nam

Upconversion nanophosphors are new promising nanomaterials to be used as biolabels for detection and imaging of cancer *** nanophosphors absorb long-wavelength excitation radiation in the infrared or near infrared region and emit shorter wavelength,higher energy radiation from ultraviolet to *** this paper,we studied the hydrothermal method and optical properties of the functionalized NaYF4:Yb^3+,Er^3+for biomedical *** synthesis,these NaYF4:Yb^3+,Er^3+nanophosphors were functionalized with aminosilanes and folic *** acid binds to the folate receptor on the surface of MCF-7 breast cancer cells and this binding promotes internalization of the nanophosphors via *** sizes of the functionalized NaYF4:Yb^3+,Er^3+@silica-N=FA(folic acid)nanophosphors can be controlled with length of the rod about 300-800 nm and diameter of the rod about 100-200 *** structure of NaYF4:Yb^3+,Er^3+is in hexagonal crystal *** photo luminescence(PL)spectra of the functionalized NaYF4:Yb^3+,Er^3+@silica-N=FA nanophosphors were *** nanophosphors emit in red color with the strongest band at 650 nm under 980 nm *** result can provide NaYF4:Er^3+,Yb^3+@silica-N=FA complex for developing fluorescence label and image tool in cancer biology and medicine.

关键词： Upconversion luminescence NaYF4:Yb^3+,Er^3+ Nanophosphors Bioimaging Cancer cell Rare earths

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Successful containment of a COVID-19 outbreak in Bach Mai Hospital by prompt and decisive responses

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Asian Pacific Journal of Tropical Medicine 2021年第5期14卷 234-235页

作者： Van Minh Hoang thi phuong thao tran thi Ngoc phuong Nguyen thi Hai Yen Nguyen Quang Tuan Nguyen Hanoi University of Public Health HanoiVietnam Bach Mai Hospital HanoiVietnam

In low-and middle-income countries,tertiary care hospitals frequently face an extremely heavy workload and shoulder an even heavier burden during the COVID-19 *** Mai Hospital(BMH),one of the leading tertiary hospitals in Vietnam,is on the frontline in the fierce battle against *** letter aims to describe how BMH tackles the COVID-19 outbreak in the hospitallevel battle,which could support policymakers in time-management and well-preparation for this unpredictable pandemic.

关键词： prompt income policy

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Operator Splitting and Local Time-Stepping Methods for transport Problems in Fractured Porous Media

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Communications in Computational Physics 2023年第10期34卷 1215-1246页

作者： Phuoc-Toan Huynh Yanzhao Cao thi-thao-phuong Hoang Department of Mathematics and Statistics Auburn UniversityAuburn 36849AlabamaUSA

this paper is concerned with efficient numerical methods for the advectiondiffusion equation in a heterogeneous porous medium containing fractures.A dimensionally reduced fracture model is considered,in which the fracture is represented as an interface between subdomains and is assumed to have larger permeability than the surrounding *** develop three global-in-time domain decomposition methods coupled with operator splitting for the reduced fracture model,where the advection and the diffusion are treated separately by different numerical schemes and with different time ***,smaller time steps can be used in the fracture-interface than in the *** first two methods are based on the physical transmission conditions,while the third one is based on the optimized Schwarz waveform relaxation approach with Ventcel-Robin transmission conditions.A discrete space-time interface system is formulated for each method and is solved iteratively and globally in *** results for two-dimensional problems with various P′eclet numbers and different types of fracture are presented to illustrate and compare the convergence and accuracy in time of the proposed methods with local time stepping.

关键词： Domain decomposition reduced fracture model operator splitting nonconforming time grids time-dependent Steklov-Poincare operator optimized Schwarz waveform relaxation

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Novel enzymatically crosslinked chitosan hydrogels with free-radical-scavenging property and promoted cellular behaviors under hyperglycemia

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Progress in Natural Science:Materials International 2020年第5期30卷 661-668页

作者： Dieu Linh tran phuong Le thi Thai Thanh Hoang thi Ki Dong Park Department of Molecular Science and Technology Ajou University Biomaterials and Nanotechnology Research Group Faculty of Applied Sciences Ton Duc Thang University

The impairment of regenerative processes induced by high blood-glucose level(hyperglycemia) and excessive reactive oxygen species(ROS) contributes to the diabetic complication progression and development. In this study, an injectable, in situ crosslinkable chitosan hydrogel with ROS-scavenging capability was developed by conjugating gallic acid onto the chitosan backbone(CGA). We hypothesized that gallic acid serves as both antioxidant and crosslinking moieties to form hydrogel in situ by means of enzymatic crosslinking with horseradish peroxidase(HRP). The rapid gelation(from 30 s) was observed by vial tilting. The mechanical properties and microstructures of CGA hydrogels can be well controlled by varying the concentrations of H2O2. The ROSscavenging ability of these CGA hydrogels was demonstrated against DPPH radical, hydroxyl radical, and total reducing power. Notably, in an in vitro hyperglycemia environment, CGA hydrogels significantly improved the proliferation and migration of human dermal fibroblast cells, which are closely related to diabetic wound healing. These results suggest that CGA hydrogels have potential as advanced materials for the treatment of diabetes-related diseases via attenuating the excessive ROS production and improving cellular behaviors.

关键词： Chitosan Gallic acid Injectable hydrogel Hyperglycemia Free-radical-scavenging

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Localized Exponential Time Differencing Method for Shallow Water Equations: Algorithms and Numerical Study

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Communications in Computational Physics 2021年第1期29卷 80-110页

作者： Xucheng Meng thi-thao-phuong Hoang Zhu Wang Lili Ju Department of Mathematics University of South CarolinaColumbiaSC 29208USA Department of Mathematics and Statistics Auburn UniversityAuburnAL 36849USA SUSTech International Center for Mathematics Southern University of Science and TechnologyShenzhenGuangdong 518055China Center for Mathematical studies Advanced Institute of Natural SciencesBeijing Normal University at ZhuhaiZhuhaiGuangdong 519087China

In this paper,we investigate the performance of the exponential time differencing(ETD)method applied to the rotating shallow water *** with explicit time stepping of the same order accuracy in time,the ETD algorithms could reduce the computational time in many cases by allowing the use of large time step sizes while still maintaining numerical *** accelerate the ETD simulations,we propose a localized approach that synthesizes the ETD method and overlapping domain *** dividing the original problem into many subdomain problems of smaller sizes and solving them locally,the proposed approach could speed up the calculation of matrix exponential vector *** standard test cases for shallow water equations of one or multiple layers are *** results show great potential of the localized ETD method for high-performance computing because each subdomain problem can be naturally solved in parallel at every time step.

关键词： Exponential time differencing domain decomposition rotating shallow water equa-tions finite volume discretization

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In vivo anticancer activity of maesopsin 4—O— β—glucoside isolated from leaves of Artocarpus tonkinensis *** Gagnep

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Asian Pacific Journal of Tropical Medicine 2016年第4期9卷 343-348页

作者： Trinh thi Thuy Dao Duc thien tran Quang Hung Nguyen Thanh Tam Nguyen thi Hoang Anh Nguyen thi Nga Nguyen thi Cuc Le phuong Mai tran Van Sung Domenico V.Delfino Do thi thao Institute of Chemistry.Vietnam Academy of Science and Technology Institute of Biotechnology Vietnam Academy of Science and Technology National Research Council Canada Measurement Science and Standards1200 Montreal RoadBuilding M-12.Ottatca.Ontario KIA OR6 Department of Medicine University of PerugiaPiazzale Gambuli.S.Andrea delle Fratte

Objective:To investigate the antitumor effect of maesopsin 4-O-β-glucoside(TAT2) isolated from the leaves of Artocarpus tonkinensis(***) *** ***:The antitumor activity of TAT2 was evaluated in Lewis lung carcinoma(LLC) tumor-bearing ***/c mice had tumors induced by implantation with 2× 10~6 LLC cells into the subcutaneous right posterior ***-bearing mice were treated orally with a range of doses of TAT2 and a standard drug,*** were observed for tumor growth and mortality *** was collected to determine hematological and biochemical *** TAT2 was isolated from an ethanolic extract of *** *** structure was determined by MS and NMR spectroscopy,and identified as *** compound did not show acute toxicity at the highest dose tested(2 OIK) mg/kg body weight).TAT2 exhibited antitumor activity by decreasing tumor growth,increasing the survival rale,and ameliorating some hematological and biochemical parameters at doses of 100 and 200 mg/kg body weight(P<0.05).Conclusions:These results indicate that TAT2 possesses clear antitumor *** to its bioavailability and low toxicity,and the fact that it could be isolated in a large scale from *** leaves,the compound shows promise as a potential anticancer drug.

关键词： Artocarpus tonkinensis BALB/c Hematological parameters Lewis lung carcinoma Maesopsin 4-0-β-glucoside

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Morphology and kinematics of the gas envelope of the Mira binary W Aquilae

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Research in Astronomy and Astrophysics 2016年第7期16卷 47-54页

作者： Do thi Hoai Pham Tuyet Nhung Pham Ngoc Diep Nguyen thi phuong Pham Tuan-Anh Nguyen thi thao Pierre Darriulat Department of Astrophysics Vietnam National Satellite CenterVAST

We analyse ALMA observations of the12CO（3-2） emission of the circumstellar envelope（CSE）of the Mira variable binary star W Aql. These provide, for the first time, spatially resolved Doppler velocity spectra of the CSE up to angular distances to the central star ofy nature of the observations（only five minutes in each of～5′′（meaning some 2000 AU）. The explorator two different configurations） does not allow for a detailed modelling of the properties of the CSE but provides important qualitative information on its morphology and kinematics. Emission is found to be enhanced along an axis moving from east/west to north-east/south-west when the angular distance from the central star projected on the plane of the sky increases from zero to four arcseconds. In parallel, the Doppler velocity distribution displays asymmetry along an axis moving from east/west to north-west/south-east. The results are discussed in the context of earlier observations, in particular of the dust morphology.

关键词： stars AGB and post-AGB (stars ) circumstellar matter stars individual(W Aql) stars mass-loss radio lines stars

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^(12)CO emission from the Red Rectangle

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Research in Astronomy and Astrophysics 2015年第12期15卷 2213-2228页

作者： Pham Tuan Anh Pham Ngoc Diep Do thi Hoai Pham Tuyet Nhung Nguyen thi phuong Nguyen thi thao Pierre Darriulat Department of Astrophysics Vietnam National Satellite CenterVAST

Observations of an unprecedented quality made by ALMA on the Red Rectangle of CO（3-2） and CO（6-5） emissions are analysed jointly with the aim of obtaining as simple as possible a description of the gas morphology and kinematics. Evidence is found for polar conical outflows and for a broad equatorial torus in rotation and expansion. Simple models of both are proposed. Comparing CO（6-5） and CO（3-2） emissions provides evidence for a strong temperature enhancement over the polar outflows. Continuum emission （dust） is seen to be enhanced in the equatorial region. Observed asymmetries are briefly discussed.

关键词： stars: AGB and post-AGB -- circumstellar matter -- radio-lines: stars-- planetary nebulae: individual (Red Rectangle)

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Assessment of Livelihood Vulnerability to Drought: A Case Study in Dak Nong Province, Vietnam

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International Journal of Disaster Risk Science 2019年第4期10卷 604-615页

作者： Nguyen thi Thanh thao Dao Nguyen Khoi tran Thanh Xuan Bernard Tychon Universite de Liege 6700 ArlonBelgium Institute for Environmental Science Engineeringand ManagementIndustrial University of Ho Chi Minh CityHo Chi Minh CityVietnam Institute of Research and Development Duy Tan UniversityDa NangVietnam Faculty of Environment University of ScienceVietnam National University Ho Chi Minh CityHo Chi Minh CityVietnam NTT Institute of Hi-Technology Nguyen Tat Thanh UniversityHo Chi Minh CityVietnam

In recent years,droughts have strongly affected the Central Highlands of Vietnam and have resulted in crop damage,yield decline,and serious water *** study investigated the livelihood vulnerability of five communities of farmers who are exposed to droughts in one of the more vulnerable regions of Vietnam—Dak Nong Province.A survey of 250 households was conducted in the five communities to collect data on the region’s sociodemographic profile,livelihood systems,social networks,health status,food and water security,drought conditions,and climate *** were aggregated using a livelihood vulnerability index and the IPCC vulnerability *** survey results indicate that Quang Phu community is the most vulnerable of the study’s communities,followed by Nam N’dir,Dak Nang,Duc Xuyen,and Dak D’ro in descending order of *** availability and livelihood strategies are the most important variables in determining the vulnerability of the five surveyed *** order to reduce vulnerability to droughts,water management practices and livelihood diversification in farming and nonfarming activities are recommended for the study area.

关键词： Agricultural drought Livelihood vulnerability Vietnam Vulnerability indicators

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