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Unravelling cOVID-19 waves in Rio de Janeiro city:Qualitative insights from nonlinear dynamic analysis

Infectious Disease Modelling 2024年第2期9卷 314-328页

作者： Adriane S.Reis Laurita dos Santos Américo cunha Jr Thaís c.R.O.Konstantyner Elbert E.N.Macao Institute of Science and Technology Federal University of São PauloSão Josédos CamposSPBrazil Physics Institute University of São PauloSão PauloSPBrazil Scientific and Technological Institute Universidade BrasilSão PauloSPBrazil Department of Applied Mathematics Rio de Janeiro State UniversityRio de JaneiroRJBrazil Paulista School of Medicine Federal University of São PauloSão PauloSPBrazil

Since the cOVID-19 pandemic was first reported in 2019,it has rapidly spread around the *** countries implemented several measures to try to control the virus *** healthcare system and consequently the general quality of life population in the cities have all been significantly impacted by the coronavirus *** different waves of contagious were responsible for the increase in the number of cases that,unfortunately,many times lead to *** this paper,we aim to characterize the dynamics of the six waves of cases and deaths caused by cOVID-19 in Rio de Janeiro city using techniques such as the Poincaréplot,approximate entropy,second-order difference plot,and central tendency *** results reveal that by examining the structure and patterns of the time series,using a set of non-linear techniques we can gain a better understanding of the role of multiple waves of cOVID-19,also,we can identify underlying dynamics of disease spreading and extract meaningful information about the dynamical behavior of epidemiological time *** findings can help to closely approximate the dynamics of virus spread and obtain a correlation between the different stages of the disease,allowing us to identify and categorize the stages due to different virus variants that are reflected in the time series.

关键词： cOVID-19 Nonlinear analysis Poincaréplot central tendency measure

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Design of a Novel Exoskeleton with Passive Magnetic Spring Self-locking and Spine Lateral Balancing

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Journal of Bionic Engineering 2024年第1期21卷 236-255页

作者： Jhon F.Rodríguez-León Betsy D.M.chaparro-rico Daniele cafolla Francesco Lago Eduardo castillo-castañeda Giuseppe carbone centro de Investigacion en ciencia Aplicada y Tecnologia Avanzada Unidad Querétaro MecatronicaInstituto Politécnico NacionalCerro Blanco 14176090 Colinas del CimatarioQuerétaroMexico Department of Mechanical Energy and Management EngineeringUniversity of CalabriaVia P.Bucci Cubo 46 C87036 RendeItaly Faculty of Science and Engineering Department of Computer ScienceSwansea UniversitySwanseaUK cESTER University of Cluj-NapocaCluj-NapocaRomania

This paper proposes a new upper-limb exoskeleton to reduce worker physical *** proposed design is based on a novel PRRRP(P-Prismatic;R-Revolute)kinematic chain with 5 passive Degrees of Freedom(DoF).Utilizing a magnetic spring,the proposed mechanism includes a specially designed locking mechanism that maintains any desired task *** proposed exoskeleton incorporates a balancing mechanism to alleviate discomfort and spinal torsional effects also helping in limb weight *** paper reports specific models and simulations to demonstrate the feasibility and effectiveness of the proposed *** experimental characterization is performed to validate the performance of the mechanism in terms of forces and physical strain during a specific application consisting of ceiling-surface drilling *** obtained results preliminarily validate the engineering feasibility and effectiveness of the proposed exoskeleton in the intended operation task thereby requiring the user to exert significantly less force than when not wearing it.

关键词： Assistive mechanism Exoskeleton Locking mechanism Bionic robot

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climate change Impacts on Environmental Hazards on the Great Hungarian Plain, carpathian Basin

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International Journal of Disaster Risk Science 2014年第2期5卷 136-146页

作者： Gábor Mezosi teodóra Bata Burghard c.Meyer Viktória Blanka Zsuzsanna Ladányi Department of Physical Geography and Geoinformatics University of SzegedEgyetem u.2-6Szeged 6722Hungary

The potential impacts of climate change on the Great Hungarian Plain based on two regional climate models,REMO and ALADIN,were analyzed using indicators for environmental *** the climate parameters(temperature,precipitation,and wind)will change in the two investigated periods(2021–2050 and 2071–2100),their influences on drought,wind erosion,and inland excess water hazards are modeled by simple predictive *** hazards on arable lands will increasingly affect the productivity of agriculture compared to the reference period(1961–1990).The models predict an increase between 12.3%(REMO)and 20%(ALADIN)in the first period,and between 35.6%(REMO)and 45.2%(ALADIN)in the second *** increase of wind erosion hazards is not as obvious(+15%for the first period in the REMO model).Inland excess water hazards are expected to be slightly reduced(-4 to 0%)by both model predictions in the two periods without showing a clear tendency on *** three indicators together give a first regional picture of potential hazards of climate *** predictive model and data combinations of the regional climate change models and the hazard assessment models provide insights into regional and subregional impacts of climate change and will be useful in planning and land management activities.

关键词： Great inland drought

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The carbon fluxes in different successional stages:modelling the dynamics of tropical montane forests in South Ecuador

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Forest Ecosystems 2017年第2期4卷 143-153页

作者： sebastian paulick claudia dislich jürgen homeier rico fischer andreas huth Department of Ecological Modelling Helmholtz Centre for Environmental Research-UFZPermoserstr1504318 LeipzigGermany Georg-August-University Gottingen Plant EcologyUntere KarspOle 237073 GottingenGermany University of Osnabriick Institute of Environmental Systems ResearchBarbarastr1249076 OsnabruckGermany iDiv German Centre for Integrative Biodiversity Research(iDiv)Halle-Jena-LeipzigDeutscher Platz 5e04103 LeipzigGermany

Background： Tropical forests play an important role in the global carbon（c） ***, tropical montane forests have been studied less than tropical lowland forests, and their role in carbon storage is not well *** forests are highly endangered due to logging, land-use and climate *** objective was to analyse how the carbon balance changes during forest ***： In this study, we used a method to estimate local carbon balances that combined forest inventory data with process-based forest *** utilised such a forest model to study the carbon balance of a tropical montane forest in South Ecuador, comparing two topographical slope positions（ravines and lower slopes vs upper slopes and ridges）.Results： The simulation results showed that the forest acts as a carbon sink with a maximum net ecosystem exchange（NEE） of 9.3 Mg c？（ha？yr）-1during its early successional stage（0–100 years）.In the late successional stage, the simulated NEE fluctuated around zero and had a variation of 0.77 Mg c？（ha？yr）–*** simulated variability of the NEE was within the range of the field *** discovered several forest attributes（e.g., basal area or the relative amount of pioneer trees） that can serve as predictors for NEE for young forest stands（0–100 years） but not for those in the late successional stage（500–1,000 years）.In case of young forest stands these correlations are high, especially between stand basal area and ***： In this study, we used an Ecuadorian study site as an example of how to successfully link a forest model with forest inventory data, for estimating stem-diameter distributions, biomass and aboveground net primary *** conclude, this study shows that process-based forest models can be used to investigate the carbon balance of tropical montane *** this model it is possible to find hidden relationships between forest attributes and forest carbon *** relationships promote a better understandin

关键词： Forest model Tropical montane forest Forest succession carbon balance Forest productivity FORMIND

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Serum levels of the novel adipokine isthmin-1 are associated with obesity in pubertal boys

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World Journal of Pediatrics 2023年第9期19卷 864-872页

作者： Francisco Javier Ruiz‑Ojeda Augusto Anguita‑Ruiz Maria c.rico Rosaura Leis Gloria Bueno Luis A.Moreno Mercedes Gil‑campos Ángel Gil concepción M.Aguilera Department of Biochemistry and Molecular Biology Ⅱ School of PharmacyUniversity of GranadaGranadaSpain Instituto de Investigación Biosanitaria Ibs.GRANADA 18012 GranadaSpain Institute of Nutrition and Food Technology“JoséMataix” Center of Biomedical ResearchUniversity of GranadaAvda.del Conocimiento S/N.18016 ArmillaGranadaSpain RG Adipocytes and Metabolism Institute for Diabetes and ObesityHelmholtz Center Munich85764 MunichGermany Barcelona Institute for Global Health ISGlobal08003 BarcelonaSpain cIBEROBN (Physiopathology of Obesity and Nutrition CB12/03/30038)Institute of Health Carlos Ⅲ(ISCⅢ)28029 MadridSpain Unit of Investigation in Human Nutrition Growth and Development of Galicia(GALINUT)University of Santiago de Compostela(USC)Santiago de CompostelaSpain Pediatric Nutrition Research Group Institute of Sanitary Research of Santiago de Compostela(IDIS)CHUS-USC15706 Santiago de CompostelaSpain Unit of Pediatric Gastroenterology Hepatology and NutritioPediatric ServiceUniversity Clinical Hospital of Santiago(CHUS)15706 Santiago de CompostelaSpain GENUD Research group Institute of Sanitary Research of Aragón(IIS Aragón)University of ZaragozaZaragozaSpain Instituto Agroalimentario de Aragón(IA2) Universidad de Zaragoza-CITAZaragozaSpain Unit of Pediatric Endocrinology University Clinical Hospital Lozano Blesa50009 ZaragozaSpain Metabolism and Investigation Unit Reina Sofa University HospitalMaimónides Institute of Biomedicine Research of Córdoba(IMIBIC)University of Córdoba14071 CórdobaSpain

Objectives To evaluate whether there is an association between the serum levels of the novel insulin-like adipokine isthmin-1(ISM1)and obesity-related phenotypes in a population of Spanish children and to investigate the plausible molecular alterations behind the alteration of the serum levels of this protein in children with *** The study population is a sub-cohort of the PUBMEP research project,consisting of a cross-sectional population of 119 pubertal children with overweight(17 boys,19 girls),obesity(20 boys,25 girls),and normal weight(17 boys,21 girls).All subjects were classified into experimental groups according to their sex,obesity,and insulin resistance(IR)*** were counted anthropometry,glucose and lipid metabolism,inflammation and cardiovascular biomarkers as well as isthmin-1(ISM1)serum *** population was intended as a discovery population to elucidate the relationship between obesity and ISM1 levels in ***,the study population had blood whole-genome DNA methylation examined,allowing deepening into the obesity–ISM1 molecular *** Higher serum ISM1 levels were observed in boys with obesity than in normal weight(P=0.004)and overweight(P=0.007)***1 serum levels were positively associated with body mass index(BMI)Z-score(P=0.005)and fat mass(P=0.058)and negatively associated with myeloperoxidase(MPO)(P=0.043)in *** we did not find associations between ISM1 serum levels and metabolic outcomes in girls,which may indicate a putative sexual dimorphism,fat mass was positively associated in all children,including boys and girls(P=0.011).DNA methylation levels in two-enhancer-related cpG sites of ISM1(cg03304641 and cg14269097)were associated with serum levels of ISM1 in *** ISM1 is associated with obesity in boys at the pubertal stage,elucidating how this protein might be of special relevance as a new biomarker of obesity in *** studies including a longitudina

关键词： children Epigenetics Isthmin-1 Obesity Puberty

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coordination corrected ab initio formation enthalpies

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npj computational Materials 2019年第1期5卷 633-644页

作者： rico Friedrich Demet Usanmaz corey Oses Andrew Supka Marco Fornari Marco Buongiorno Nardelli cormac Toher Stefano curtarolo Department of Mechanical Engineering and Materials Science Duke UniversityDurhamNC 27708USA center for Materials Genomics Duke UniversityDurhamNC 27708USA Department of Physics and Science of Advanced Materials Program Central Michigan UniversityMount PleasantMI 48859USA Department of Physics and Department of chemistry University of North TexasDentonTX 76203USA Materials Science Electrical EngineeringPhysics and ChemistryDuke UniversityDurhamNC 27708USA Fritz-Haber-Institut der Max-Planck-Gesellschaft 14195 Berlin-DahlemGermany

The correct calculation of formation enthalpy is one of the enablers of ab-initio computational materials *** several classes of systems(***)standard density functional theory produces incorrect *** we propose the“coordination corrected enthalpies”method(ccE),based on the number of nearest neighbor cation–anion bonds,and also capable of correcting relative stability of *** uses calculations employing the Perdew,Burke and Ernzerhof(PBE),local density approximation(LDA)and strongly constrained and appropriately normed(ScAN)exchange correlation functionals,in conjunction with a quasiharmonic Debye model to treat zero-point vibrational and thermal *** benchmark,performed on binary and ternary oxides(halides),shows very accurate room temperature results for all functionals,with the smallest mean absolute error of 27(24)meV/atom obtained with *** zero-point vibrational and thermal contributions to the formation enthalpies are small and with different signs—largely canceling each other.

关键词： corrected vibrational oxides

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Natural epitope variants of the hepatitis c virus impair cytotoxic T lymphocyte activity

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World Journal of Gastroenterology 2010年第16期16卷 1953-1969页

作者： Shuping Wang rico Buchli Jennifer Schiller Jianen Gao Rodney S VanGundy William H Hildebrand David D Eckels Department of Pathology University of Utah Pure Protein L.L.c. Oklahoma CityOK 73104United States Jennifer SchillerJianen GaoDepartment of PediatricsMedical College of Wisconsin Department of Pediatrics Medical College of Wisconsin Pure Protein L.L.c. Department of Microbiology and Immunology Health Sciences CenterUniversity of Oklahoma

AIM:To understand how interactions between hepatitis c virus(HcV) and the host's immune system might lead to viral persistence or effective elimination of ***:Nucleotides 3519-3935 of the non-structural 3(NS3) region were amplified by using reverse transcription polymerase chain reaction(PcR).PcR products of the HcV NS3 regions were integrated into a PcR T7TOPO TA vector and then sequenced in both directions using an automated DNA *** major histocompatibility complex binding levels of wild-type and variant peptides were performed by fluorescence polarization-based peptide competition *** with wild type and variant sequences of NS3 were synthesized locally using F-moc chemistry and purified by high-performance liquid *** cytotoxic T lymphocytes(cTLs) clones toward HcV NS3 wild-type peptides were generated through limiting dilution *** cTL clones specifically recognizing HcV NS3 wild-type peptides were tested by tetramer staining and flow *** activity of cTL clones was measured using target cells labeled with the fluorescence enhancing ligand,DELFIA ***:The pattern of natural variants within three human leukocyte antigen(HLA)-A2-restricted NS3 epitopes has been examined in one patient with chronic HcV infection at 12,28 and 63 mo *** obtained may provide convincing evidence of immune selection pressure for all epitopes *** analysis of the extensive sequence variation found within these NS3 epitopes favors a Darwinian selection model of variant *** within the epitopes coincided with the decline of cTL responses,and peptide-binding studies suggested a signif icant impact of the mutation on T cell recognition rather than peptide presentation by HLA *** most variants were either not recognized or elicited low responses,such could antagonize cTL responses to target cells pulsed with wild-type ***:cross-

关键词： Epitopes Human T cells cytotoxic Anergy Viral

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Effects of Slash-and-Burn Practices on Soil Quality at Different Landscape Positions in the Raumoco Watershed, Municipality of Lautem, Timor-Leste

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Open Journal of Ecology 2022年第7期12卷 483-498页

作者： Delfim Da costa Decibel V. Faustino-Eslava rico c. Ancog National University of Timor Lorosae Dili Timor-Leste University of the Philippines Los Bañ os Laguna Philippines

Slash-and-burn practices used by farmers in prior growing periods could affect soil quality, particularly topsoil properties. This study aimed to assess soil biophysical and chemical properties at different landscape levels within the watershed site. Soil samples were collected by a core method in the topsoil layer in slash-and-burn sites. Field analysis was on bulk density and porosity by the gravimetric method, while laboratory analysis was done on organic matter by the Loss on Ignitions Method and other macronutrients for crops (total nitrogen, phosphorus availability, and potassium availability) followed standard analytical methods. To see if there was a significant difference between sites, DMRT 5% was used. The results of the study showed slash-and-burn practice affects soil physical properties such that high bulk density in upstream, midstream, and downstream ranged from 1.55 g/cm3 to 1.71 g/cm3, 1.55 g/cm3 to 1.80 g/cm3, and 1.38 g/cm3 to 1.79 g/cm3 respectively. Poor porosity in upstream, midstream, and downstream ranged from 33.91% to 40.06%, 30.38% to 41.75%, and 30.91% to 46.65%, respectively. Organic matter content was low in the upstream, midstream, and downstream areas, ranging from 2.86% to 3.39%, 2.58% to 3.88%, and 2.91% to 3.88%, respectively. However, soil pH remains neutral, and nitrogen levels are low but near-optimal in the upstream and very low in the midstream and downstream. Phosphorus is extremely high upstream but very low in midstream and downstream. However, potassium remains at a low level close optimum level in the entire watershed.

关键词： Timor-Leste Raumoco Watershed Slash and Burn Farming

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Frequency-Domain Receivers for Rate-1 Space-Time Block codes

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International Journal of communications, Network and System Sciences 2009年第9期2卷 845-861页

作者： Mário Marques da Silva Rui Dinis Américo M. c. correia 不详

This paper considers iterative frequency-domain receivers for block transmission techniques with rate-1 Space Time Block coding (STBc) for two and four transmit antennas using both Orthogonal Frequency Division Multiplexing (OFDM) and Single-carrier (Sc) schemes. The proposed receiver includes an interference canceller which enhances the performance of the non-orthogonal STBc scheme with 4 transmit antennas, allowing performances close to those of orthogonal codes. Our performance results show that combining STBc with block transmission techniques allows excellent performances.

关键词： Sc-FDE Turbo Equalization STBc OFDM

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Amphibians and Reptiles of cebu,Philippines：The Poorly Understood Herpetofauna of an Island with Very Little Remaining Natural Habitat

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Asian Herpetological Research 2016年第3期7卷 151-179页

作者： christian E.SUPSUP Nevong M.PUNA Augusto A.ASIS Bernard R.REDOBLADO Maria Fatima G.PANAGUINIT Faith M.GUINTO Edmund B.rico Arvin c.DIESMOS Rafe M.BROWN Neil Aldrin D.MALLARI Fauna and Flora International- Philippines Foggy Heights Subdivision Brgy. San Jose Tagaytay City Philippines Biology Department De La Salle University 2401 Taft Avenue Manila Philippines cebu Biodiversity conservation Foundation 41 Edison Street Lahug Cebu City Cebu cebu Technological University - Argao campus Ed Kintanar Street Lamacan 6021 Argao Cebu Philippine National Museum Zoology Division Herpetology Section. Rizal Park Buvg os St. Manila Philippines Department of Ecology and Evolutionary Biology and KU Biodiversity Institute University of Kansas Lawrence Kansas 66045 USA

Despite its proximity to other well studied islands, cebu has received little attention from herpetologists, most likely because of early deforestation and the perception very little natural habitat remains for amphibians and reptiles. In this study, we present a preliminary assessment of island＇s herpetofauna, focusing our field work on cebu＇s last remaining forest fragments and synthesizing all available historical museum distribution data. We surveyed amphibians and reptile populations using standardized methods to allow for comparisons between sites and assess sufficiency of sampling effort. Fieldwork resulted in a total of 27 species recorded from five study sites, complementing the 58 species previously known from the island. Together, our data and historical museum records increase the known number of cebu＇s resident species to 13 amphibians（frogs） and 63 reptiles（lizards, snakes, turtle, crocodile）. We recorded the continued persistence cebu＇s rare and endemic lizard（Brachymeles cebuensis） and secretive snakes such as Malayotyphlops hypogius, and Ramphotyhlops cumingii, which persist despite cebu＇s long history of widespread and continuous habitat degradation. Most species encountered, including common and widespread taxa, appeared to persist at low population abundances. To facilitate the immediate recovery of the remaining forest fragments, and resident herpetofauna, conservation effort must be sustained. However, prior to any conservation interventions, ecological baselines must be established to inform the process of recovery.

关键词： persist likely historical habitat remaining resident island facilitate museum populations

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