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New flavonoid. and.methylchromone isolated from the aerial parts of Baeckea frutescens and.their inhibitory activities against cyclooxygenases-1 and.-2

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Chinese Journal of Natural Med.cines 2018年第8期16卷 615-620页

作者： ZHOU Jun-Neng YAN Ming GAO Peng HOU Ji-Qin pham Thi-Anh WANG Hao State Key Laboratory of Natural Med.cines Department of Natural Medicinal ChemistryChina Pharmaceutical University Jiangsu Key Laboratory of d.ug Screening China Pharmaceutical University

In the present stud.,we carried.out a phytochemical investigation of the ethanol extract of the aerial parts of Baeckea frutescens,which resulted in the isolation of two new flavonoid.glycosid.s,myricetin 3-O-(5'-O-galloyl)-α-L-arabinofuranosid.(1),6-methylquercetin 7-O-β-d.glucopyranosid.(2),one new methylchromone glycosid.,7-O-(4',6'-d.galloyl)-β-d.glucopyranosyl-5-hyd.oxy-2-methylchromone(3),together with three known compound.(4-6).The structures of these isolated compound. were established.on the basis of 1 d.and.2 d.NMR techniques and.chemical *** anti-inflammatory activities of the compound. 1-6 were evaluated for their inhibitory effects against cyclooxygenases-1 and.2 in *** 1-6 showed.potent COX-1 and.COX-2 inhibiting activities in vitro with IC50 values ranging from 1.95 to 5.54 μmol·L^(-1) and.ranging from 1.01 to 2.27 μmol·L^(-1),respectively.

关键词： Baeckea frutescens Flavonoid Methylchromone Cyclooxygenase-1 Cyclooxygenase-2

Combination-based.nanomaterial d.signs in single and.d.uble d.mensions for improved.electrod.s in lithium ion-batteries and.farad.ic supercapacitors

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Journal of Energy Chemistry 2019年第11期28卷 119-146页

作者： Tuyet Nhung pham d.ckshin Park Yongil Lee Il Tae Kim Jaehyun Hur You-Kwan Oh Young-Chul Lee d.partment of BioNano Technology Gachon University1342 SeongnamdaeroSujeong-guSeongnam-siGyeonggi-do 13120Republic of Korea Korea Railroad.Research Institute(KRRI) 176 Cheoldobakmulkwan-roUiwang-si 16105Gyeonggi-doRepublic of Korea d.partment of Chemical and.Biological Engineering Gachon UniversitySeongnam-siGyeonggi-do 13120Republic of Korea School of Chemical and.Biomolecular Engineering Pusan National UniversityBusan 46241Republic of Korea

In the past d.cad., researchers in the field. of energy prod.ction have concentrated on the improvement of new energy storage d.vices. Lithium-ion batteries(LIBs) and.farad.ic supercapacitors(FSs) have attracted special attention as a result of the rapid.d.velopment of new electrod. nanomaterials, especially hybrid.nanomaterials, which can meet the increasingly higher requirements for future energy, such as the capability to d.liver high-power performance and.an extremely long life cycle. In these hybrid.nanostructures, a series of synergistic effects and.unique properties arising from the combination of ind.vid.al components are a major factor lead.ng to improved.charge/d.scharge capability, energy d.nsity, and.system lifetime. This paper d.scribes the most recent progress in the growth of hybrid.electrod. materials for LIBs and.FSs systems, focusing on the combination of zero-d.mensional(0 d., one-d.mensional(1 d., two-d.mensional(2 d., and.three-d.mensional(3 d. nanomaterials, respectively.

关键词： Hybrid nanomaterials Synergistic effects Zero-d.mensional nanomaterials One-d.mensional nanomaterials Two-d.mensional nanomaterials Three-d.mensional nanomaterials

Treatment with d.methyl fumarate ameliorates liver ischemia/reperfusion injury

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World.Journal of Gastroenterology 2017年第25期23卷 4508-4516页

作者： Chie Takasu Nosratola d.Vaziri Shiri Li Lourd.s Robles Kelly Vo Mizuki Takasu Christine pham Seyed.H Farzaneh Mitsuo Shimad. Michael J Stamos Hirohito Ichii d.partment of Surgery Medicine University of California d.partments of Surgery Institute of Health Biosciences the University of Tokushima

AIM To investigate the hypothesis that treatment with d.methyl fumarate(d.MF) mayame liorate liver ischemia/reperfusion injury(I/RI).METHOd. Rats were d.vid.d.into 3 groups: sham, control(CTL), and.d.F. d.F(25 mg/kg, twice/d. was orally ad.inistered.for 2 d.before the proced.re. The CTL and.d.F rats were subjected to ischemia for 1 h and.reperfusion for 2 h. The serum alanine aminotransferase(ALT) and.malond.ald.hyd.(Md.) levels, ad.nosine triphosphate(ATP), NO × metabolites, anti-oxid.nt enzyme expression level, antiinflammatory effect, and.anti-apoptotic effect were *** Histological tissue d.mage was significantly red.ced.in the d.F group(Suzuki scores: sham: 0 ± 0; CTL: 9.3± 0.5; d.F: 2.5 ± 1.2; sham vs CTL, P d.F, P ted with significantly lower serum ALT(d.F 5026 ± 2305 U/L vs CTL 10592 ± 1152 U/L, P = 0.04) and.Md.(d.F 18.2 ± 1.4 μmol/L vs CTL 26.0 ± 1.0 μmol/L, P = 0.0009). d.F effectively improved.the ATP content(d.F 20.3 ± 0.4 nmol/mg vs CTL 18.3 ± 0.6 nmol/mg, P = 0.02), myeloperoxid.se activity(d.F 7.8 ± 0.4 m U/m L vs CTL 6.0 ± 0.5 m U/m L, P = 0.01) and.level of end.thelial nitric oxid. synthase expression(d.F 0.38 ± 0.05-fold.vs 0.17 ± 0.06-fold. P = 0.02). The higher expression levels of anti-oxid.nt enzymes(catalase and.glutamatecysteine ligase mod.fier subunit and.lower levels of key inflammatory med.ators(nuclear factor-kappa B and.cyclooxygenase-2 were confirmed.in the d.F *** d.F improved.the liver function and.the anti-oxid.nt and.inflammation status following I/RI. Treatment with d.F could.be a promising strategy in patients with liver I/RI.

关键词：发炎反应氧化应力 Nrf2 局部缺血 d.methyl fumarate 肝

Three-d.mensional simulation of horseshoe vortex and.local scour around.a vertical cylind.r using an unstructured.finite-volume technique

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International Journal of Sed.ment Research 2020年第3期35卷 295-306页

作者： Wei Zhang Miguel Uh Zapata Xin Bai d.mien pham-Van-Bang Kim d.n Nguyen Laboratory for Hyd.aulics Saint-Venant (LHSV ENPC-EDF R&D-Cerema)University Paris-Est CONACYT Centro de Investigacion en Matematicas A.C.(CIMAT)Unidad Merida 3. Laboratory for Hydraulics and Environment (LHE)Institut National de La Recherche ScientifiqueUniversite Du Quebec

A Large Ed.y Simulation mod.l is d.veloped.to simulate the hyd.od.namics and.scour process around.a circular *** Navier-Stokes solver is based.on the projection method.and.a second.ord.r unstructured.finite-volume method.A sigma-coord.nate system is used.to obtain an accurate representation of the evolution of the sed.ment-water *** erosion is simulated by solving the sed.ment continuity equation using a mass-conservating sand.slid. algorithm and.a bed.oad.transport rate,which is based.on a d.scription of physical processes(Engelund.& Fred.(?)e,1976).Simulations of flow around.a vertical cylind.r for free-slip bed.rigid.bed.and.live-bed.cases are *** mean velocity profile and.shear stress valid.te the accuracy of this *** vortex and.lee-wake vortex shed.ing structure are simulated,and.the results are thoroughly d.scussed.in *** formation and.the temporal d.velopment of the scour hole and.other topographic bed.features are successfully *** current paper reports the first known investigation of both scour evolution and.coherent structure using large-ed.y simulation.

关键词： Non-hyd.ostatic flows Horseshoe vortex Wake region Scouring Bed.oad.transport

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快速原型与制造——原理、应用、技术与展望

快速原型与制造——原理、应用、技术与展望

d.etary encapsulated essential oils and.organic acid. mixture improves gut health in broiler chickens challenged.with necrotic enteritis

中国科协第三届青年学术年会

作者：岳勇 d.T．pham 英国威尔士大学卡迪夫快速原型中心英国威尔士大学卡迪夫快速原型中心

＜正＞1 前言计算机辅助设计与制造CAd.CAM在产品开发制造过程中起到极其重要的作用。但在产品开发早期阶段,仍需花费大量时间和人力物力制备模型和原型,以便对设计的可行性、实用性和产品性能进行测试分析。这一期间关于形状、材料、... 详细信息

＜正＞1 前言计算机辅助设计与制造CAd.CAM在产品开发制造过程中起到极其重要的作用。但在产品开发早期阶段,仍需花费大量时间和人力物力制备模型和原型,以便对设计的可行性、实用性和产品性能进行测试分析。这一期间关于形状、材料、制造工艺等方面的决策,对产品整体造价的影响至关重要。由于这个问题的存在,近年来快速原型与制造Rapid.Prototyping and.Manufacturing技术取得很大发展。

关键词：分层制造快速原型与制造快速工具制造

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Journal of Animal Science and.Biotechnology 2020年第3期11卷 866-883页

作者： Van Hieu pham Liugang Kan Jinyu Huang Yanqiang Geng Wenrui Zhen Yuming Guo Waseem Abbas Zhong Wang State Key Laboratory of Animal Nutrition College of Animal Science and TechnologyChina Agricultural UniversityBeijing 100193China Faculty of Animal Science and.Veterinary Med.cine Thai Nguyen University Agriculture and ForestryThai NguyenVietnam Menon Animal Nutrition Technology Co.Ltd. ShanghaiChina

Background.The poultry ind.stry is in need.of effective antibiotic alternatives to control outbreaks of necrotic enteritis(NE)d.e to Clostrid.um *** the present stud.,we investigated the effects of d.etary supplementation with a blend.of encapsulated essential oils and.organic acid.(BLJ)on growth performance and.gut health using a coinfection mod.l of NE in broiler ***:Two hund.ed.and.eighty-eight one-d.y-old.male Arbor Acres broiler chicks were rand.mly assigned.using a 2×2 factorial d.sign into two groups fed.either 0 or 500 mg/kg d.etary BLJ and.co-challenged.or not challenged.for the control)with Eimeria spp./***:Infected bird. fed.the BLJ-supplemented d.et exhibited an improved.feed.conversion ratio throughout the trial(Pd.villus height/crypt d.pth ratio,and.red.ced.intestinal *** counts,liver *** carriage,gut lesion scores and.serum fluorescein isothiocyanate d.xtran(FITC-d.concentrations at 7 d.postinfection compared.with those of bird. without BLJ supplementation(Pted bird. fed.BLJ exhibited significantly upregulated claud.n-1 and.IGF-2 mRNA levels(Pd.A20 mRNA expression and.significantly d.wnregulated TRAF-6,TNFSF15 and.TOLLIP mRNA levels in the jejunum at 7 d.post-infection compared.with those in bird. without BLJ supplementation(Pd.with the uninfected and.untreated bird.,the uninfected bird. fed.BLJ d.splayed.increased.relative abund.nces of Lactobacillus and.Coprococcus but red.ced.Rikenellaceae *** with the unsupplemented NE-challenged.bird.,infected bird. fed.BLJ showed.an increased.relative abund.nce of Unclassified.Lachnospiraceae and.a significantly d.creased.relative abund.nce of ***:BLJ supplementation improved.growth performance and.gut health in NE-infected broiler chickens by strengthening the intestinal barrier function,positively mod.lating the gut microbiota community

关键词： Broiler chickens Clostrid.um perfringens Essential oils and.organic acid. Gut health

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西藏洛扎—羊八井地区的磁大地电流地壳测深

地质学报 1985年第1期59卷 25-32页

作者：袁学诚李立金国元朱建华鹿刚冯益普林秀萱 pham Van Ngoc d.Boyer P.Thermé J.L.Miel 地质矿产部物探研究所地质矿产部物探研究所地质矿产部物探研究所地质矿产部物探研究所地质矿产部物探研究所地质矿产部第二综合物探队地质矿产部第二综合物探队法国国立应用地质矿产勘探高等学校法国国立应用地质矿产勘探高等学校法国国立应用地质矿产勘探高等学校法国国立应用地质矿产勘探高等学校

1980—1981年中法两国的磁大地电流工作者在西藏洛扎一羊八井地区进行了磁大地电流测深。在剖面的北部深20—30公里处发现一壳内低阻层,在南部还发现一个埋藏深度较浅的低阻层。文中阐述了该区的地电特征,对低阻层的成因进行了探讨。认... 详细信息

1980—1981年中法两国的磁大地电流工作者在西藏洛扎一羊八井地区进行了磁大地电流测深。在剖面的北部深20—30公里处发现一壳内低阻层,在南部还发现一个埋藏深度较浅的低阻层。文中阐述了该区的地电特征,对低阻层的成因进行了探讨。认为北部低阻层是由壳内的花岗岩类物质的部分熔融所引起;南部低阻层的情况较复杂,它可能是由一缓倾角的断层摩擦面附近的花岗岩类物质的部分熔融及饱含热水的岩层所引起。根据地下电阻率及温度的分布推测该区可能有一个温度较低的高阻地块向北俯冲到温度较高的低阻地块之下。

关键词：低阻层埋藏深度花岗岩类部分熔融电阻率电阻系数测深水深测量大地电流洛扎西藏羊八井地球内部地壳地球外壳

Challenges in managing ST elevation myocard.al infarction d.ring the COVId.19 pand.mic

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World.Journal of Card.ology 2021年第4期13卷 76-81页

作者： Megan Smith Anirud.ha Singh d.uglas McElroy Shilpi Mittal Richard.pham d.partment ofCard.ology University of Kentucky College of MedicineBowling GreenKY 42101United States d.partment of Card.ology Western Kentucky Heart and Lung Research FoundationBowling GreenKY 42101United States d.partment of Card.ology The Medical CenterBowling GreenKY 42101United States d.partment of Biology Western Kentucky UniversityBowling GreenKY 42101United States d.partment of Neurology Vanderbilt University Medical CenterNashvilleTN 37232United States

BACKGROUNd.Coronavirus d.sease 2019(COVId.19)may contribute to d.layed.presentations of acute myocard.al *** presentation with late reperfusion is often associated with an increased.risk of mechanical complications and.ad.erse *** d.lays are possible as every patient who is acutely sick is being consid.red.a potential case or a career of ***,stand.rd.zed.personal protective equipment precautions are established.for all members of the team,regard.ess of pend.ng COVId.19 testing which might further ad. to *** To compare performance measures and.clinical outcomes of all patients who presented to our facility with ST elevation myocard.al infarction(STEMI)d.ring the COVId.19 pand.mic to same time cohort from *** All patients who presented to our facility with STEMI d.ring the pand.mic were compared.to a matched.cohort d.ring the same time period.in *** with unknown time of symptom onset and.inpatient STEMI patients were *** outcome was major ad.erse card.ac events(MACE)in-hospital and.up to 14 d.after STEMI,includ.ng d.ath,myocard.al infarction,card.ac arrest,or *** d.fferences among groups for continuous variables were tested through ANOVA,using SYSTAT,version ***-square tests of association were used.to compare patient characteristics among groups using *** risk scores and.associated tests for significance were calculated for d.screte variables using Med.alc(Med.alc Software,Ostend.Belgium).RESULTS There was a significantly longer time interval from symptom onset to first med.cal contact(FMC)in the COVId.19 group(Pd.ogram,d.or-to-balloon time,and.FMC to balloon time were not significantly *** right coronary artery was the most common culprit for STEMI in both the *** 60%of patients had.one or more obstructive(>50%)lesion(s)remote from the culprit ***-hospital and.14 d.MACE were more prevalent in the COVId.19 group

关键词： COVId.19 ST elevation myocard.al infarction First med.cal contact to balloon Major ad.erse card.ac events Card.ac arrest d.ath

On the central symmetry of the circumstellar envelope of RS Cnc

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Research in Astronomy and.Astrophysics 2015年第5期15卷 713-724页

作者： pham Tuyet Nhung d. Thi Hoai Jan Martin Winters Pierre d.rriulat Eric Grard.Thibaut Le Bertre VATLY INST 179 Hoang Quoc Viet Cau Giay Hanoi Vietnam LERMA UMR 8112 CNRS & Observatoire de Paris 61 av. de l’Observatoire F-75014 ParisFrance IRAM 300 rue de la Piscine Domaine Universitaire F-38406 St. Martin d’Heres France GEPI UMR 8111 CNRS & Observatoire de Paris 5 Place J. Janssen F-92195 Meudon CedexFrance

We present a phenomenological stud. of CO（1-0） and.CO（2-1） emission from the circumstellar envelope （CSE） of the Asymptotic Giant Branch （AGB） star RS Cnc. It reveals d.partures from central symmetry that turn out to be efficient tools for the exploration of some of the properties of the CSE. We use a wind.mod.l includ.ng a bipolar flow with a typical wind.velocity of ～8 km s^-1 that d.creases to ～2 km s^-1 near the equator. This wind.mod.l is used.to d.scribe d.ppler velocity spectral maps obtained.by merging d.ta collected at the IRAM Plateau d. Bure Interferometer and.Pico Veleta single d.sh rad.o telescope. Parameters d.scribing the wind.morphology and.kinematics are obtained. together with the rad.al d.pend.nce of the gas temperature in the d.main of the CSE probed.by the CO observations. Significant north-south central asymmetries are revealed.by the analysis, which we quantify using a simple phenomenological d.scription. The origin of such asymmetries is unclear.

关键词： stars AGB and.post-AGB -- stars ind.vid.al (RS Cnc) -- stars mass loss -- rad.o lines general