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Common sense and other writings

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作者： Thomas paine edited by J. M. Opal.

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Modification of tooth development by heat shock protein 60

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International Journal of Oral Science 2016年第1期8卷 24-31页

作者： Tamas Papp Angela Polyak Krisztina Papp Zoltan Meszar Roza Zakany Eva Meszar-Katona paine Terdik Tiinde Chang Hwa Ham Szabolcs Felszeghy Department of Anatomy Histologyand EmbryologyFaculty of MedicineUniversity of DebrecenDebrecenHungary Scoliosis Research Institute Korea University Guro HospitalSeoul Department of Oral Anatomy Faculty of DentistryUniversity of DebrecenDebrecenHungary

several heat shock proteins have been investigated in relation to tooth development, no available information is available about the spatial and temporal expression pattern of heat shock protein 60 （Hsp 60）. To characterize Hsp 60 expression in the structures of the developing tooth germ, we used Western blotting, immunohistochemistry and in situ hybridization. Hsp 60 was present in high amounts in the inner and outer enamel epithelia, enamel knot （EK） and stratum intermedium （SI）. Hsp 60 also appeared in odontoblasts beginning in the bell stage. To obtain data on the possible effect of Hsp 60 on isolated lower incisors from mice, we performed in vitro culturing. To investigate the effect of exogenous Hsp 60 on the cell cycle during culturing, we used the 5-bromo-2- deoxyuridine （BrdU） incorporation test on dental cells. Exogenously administered Hsp 60 caused bluntness at the apical part of the 16.5-day-old tooth germs, but it did not influence the proliferation rate of dental cells. We identified the expression of Hsp 60 in the developing tooth germ, which was present in high concentrations in the inner and outer enamel epithelia, EK, SI and odontoblasts. High concentration of exogenous Hsp 60 can cause abnormal morphology of the tooth germ, but it did not influence the proliferation rate of the dental cells. Our results suggest that increased levels of Hsp 60 may cause abnormalities in the morphological development of the tooth germ and support the data on the significance of Hsp during the developmental processes.

关键词： enamel organ heat shock protein 60 inhibitor of κB kinase morphology mouse tooth development

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Terahertz atmospheric windows for high angular resolution terahertz astronomy from Dome A

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Advances in Polar Science 2019年第1期30卷 76-80页

作者： Hiroshi MATSUO Shengcai SHI Scott paine Qijun YAO Zhenhui LIN National Astronomical Observatory of Japan Purple Mountain Observatory Key Laboratory of Radio Astronomy Chinese Academy of Sciences Smithsonian Astrophysical Observatory

Atmospheric transmission from Dome A, Antarctica, presents new possibilities in the field of terahertz astronomy, where space telescopes have been the only observational tools until now. Using atmospheric transmission measurements from Dome A with a Fourier transform spectrometer, transmission spectra and long-term stabilities have been analyzed at 1.461 THz, 3.393 THz, 5.786 THz and 7.1 THz, which show that important atmospheric windows for terahertz astronomy open for a reasonable length of time in the winter season. With large aperture terahertz telescopes and interferometers at Dome A, high angular resolution terahertz observations are foreseen of atomic fine-structure lines from ionized gas and a water ice feature from protoplanetary disks.

关键词： terahertz astronomy atmospheric window Fourier transform spectroscopy terahertz telescope terahertz interferometry

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布朗运动的弱收敛

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东北师大学报（自然科学版） 1990年第2期22卷 1-17页

作者： paine,TB

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WEAK CONVERGENCE TO BROWNIAN MOTION

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东北师大学报(自然科学版) 1990年第2期 1-17页

作者： Thomas B.paine Department of Mathematics Southern Illinois University Carbondale,IL 62901-4408

Let X;=(X;（t）: t≥0) denote the continuous polygonalfunction whose vertices are where s;=z;+…+z;and the Z;’s are independent random variables with Ez;=0,vat z;=σ;;v;=σ;+…+σ;.Under standard condition onexpected values of ,itis shown that Xm converges weakly to Brownian motion in thetopology induced by the metric ρ（x,y） =wherex and y denote real continuous functions on [0,∞) and t log log tis taken to be 1 when t≤e;.A comparison is made withSakhanenkos’ similar *** is also shown thatconvergence,in probability,of the Skorokhod embedding times isa necessary condition for weak convergence to Brownian motion onthe unit interval under the supremum norm

关键词： Brownian motion weak convergence

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