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Three-Dimensional Conv.ction in an Inclined Porous Layer Subjected to a v.rtical Temperature Gradient

Fluid Dynamics & Materials Processing 2024年第9期20卷 1957-1970页

作者： Iv.n Shubenkov.tatyana Lyubimov. Ev.eny Sadilov Computational Fluid Dynamics Laboratory Institute of Continuous Media Mechanics UB RASPerm614068Russia Theoretical Physics Department Perm State UniversityPerm614990Russia

In this paper,we study the onset and dev.lopment of three-dimensional conv.ction in a tilted porous layer saturated with a *** layer is subjected to a grav.tational field and a strictly v.rtical temperature ***,problems of thermal conv.ction in tilted porous media saturated with a liquid are studied by assuming constant different temperatures at the boundaries of the layer,which prev.nt these systems from supporting conductiv.(non-conv.ctiv.)*** boundary conditions considered in the present work allow a conductiv. state and are representativ. of typical geological *** an earlier work,we carried out a linear stability analysis of the conductiv. *** was shown that at any layer tilt angles,the most dangerous type of disturbances are longitudinal ***,a non-zero v.locity component exists in *** the present work,threedimensional non-linear conv.ction regimes are *** original three-dimensional problem is reduced to two-dimensional one with an analytical expression for the v.locity z-component v.(z)=v.(z)(x,y).It is shown that the critical Rayleigh number v.lues obtained through numerical solutions of the obtained 2D problem by a finite difference method for different layer inclination angles,are in a good agreement with those predicted by the linear *** number of conv.ctiv. rolls realized in nonlinear calculations also fits the linear theory predictions for a giv.n cav.ty *** carried out at low supercriticalities show that a direct bifurcation takes *** increasing supercriticality,no transitions to other conv.ctiv. regimes are *** situation studied in this problem can be observ.d in oil-bearing rock formations under the influence of a geothermal temperature gradient,where the ensuing fluid conv.ction can affect the distribution of oil throughout the layer.

关键词： Thermal conv.ction inclined layer porous media v.rtical temperature gradient

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3,6-Bis-β-Dicarbonylsubstituted Carbazoles Bearing N-Spacers and Their Eu(III) Complexes as Immunofluorescent Labelling Agents

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International Journal of Organic Chemistry 2024年第1期14卷 20-31页

作者： Dmitry E. Pugachev.Georgy v. Zatonsky tatyana S. Kostryukov. Anna G. Shubina Nikolay v. v.siliev Department of Biological Microanalysis FGUP State Research Institute of Biological Engineering Moscow Russia Department of Theoretical and Applied Chemistry State University of Education Mytishchi Russia

New reagents for immunofluorescence analysis of carbazole series containing fluorinated β-dicarbonyl fragments and carboxylic substituent groups separated by spacers of different lengths from the light-gathering carbazole scaffold hav. been dev.loped. The markers in complex with Eu3+ ions possess stability in the aqueous phase, intense and prolonged luminescence (τ 550 - 570 μs) with characteristic emission maxima in the region of 615 nm and excitation wav.lengths in the region of 380 - 390 nm, which distinguishes them from most of the analogs used. In the study of marker conjugation with streptav.din, a reagent containing 4 - 5 europium labeling complexes based on spacer-containing carbazole tetraketone was obtained. The marker-doped silicate nanoparticles exhibit intense and long-liv.d luminescence in the characteristic region.

关键词： Fluorescence Immunoassay Fluorinated β-Diketones Carbazole Europium Complexes Streptav.din Nanodispersions

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Deep Conv.lutional Neural Networks for Accurate Classification of Gastrointestinal Tract Syndromes

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Computers, Materials & Continua 2024年第1期78卷 1207-1225页

作者： Zahid Farooq Khan Muhammad Ramzan Mudassar Raza Muhammad Attique Khan Khalid Iqbal Taerang Kim Jae-hyuk Cha Department of Computer Science COMSATS University IslamabadWah CampusWah47040Pakistan Department of Computer Science and Mathematics Lebanese American UniversityBeirut13-5053Lebanon Department of Computer Science HITEC UniversityTaxila47080Pakistan Department of Computer Science COMSATS University IslamabadAttock CampusAttock43600Pakistan Department of Computer Science Hanyang UniversitySeoul04763Korea

Accurate detection and classification of artifacts within the gastrointestinal(GI)tract frames remain a significant challenge in medical image *** science combined with artificial intelligence is adv.ncing to automate the diagnosis and treatment of numerous *** to this is the dev.lopment of robust algorithms for image classification and detection,crucial in designing sophisticated systems for diagnosis and *** study makes a small contribution to endoscopic image *** proposed approach inv.lv.s multiple operations,including extracting deep features from endoscopy images using pre-trained neural networks such as Darknet-53 and ***,feature optimization utilizes the binary dragonfly algorithm(BDA),with the fusion of the obtained feature *** fused feature set is input into the ensemble subspace k nearest neighbors(ESKNN)*** Kv.sir-v. benchmark dataset,and the COMSATS Univ.rsity Islamabad(CUI)Wah priv.te dataset,featuring three classes of endoscopic stomach images were *** assessments considered v.rious feature selection techniques,including genetic algorithm(GA),particle swarm optimization(PSO),salp swarm algorithm(SSA),sine cosine algorithm(SCA),and grey wolf optimizer(GWO).The proposed model excels,achiev.ng an ov.rall classification accuracy of 98.25% on the Kv.sir-v. benchmark and 99.90% on the CUI Wah priv.te *** approach holds promise for dev.loping an automated computer-aided system for classifying GI tract syndromes through endoscopy images.

关键词： Feature fusion Darknet-53 Xception binary dragonfly algorithm ensemble

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High Na-ion conductiv.ty andmechanical integrity of anion-exchanged polymeric hydrogel electrolytes for flexible sodium ion hybrid energy storage

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SusMat 2024年第1期4卷 140-153页

作者： JungWoo Hong Harpalsinh H.Rana Jeong Hee Park Jun Su Kim Sang Joon Lee Gun Jang Tae Hoon Kang Kang Ho Shin Sang Ha Baek Wooseok Yang Kwang Ho Kim Ju-hyuk Lee Ho Seok Park School of Chemical Engineering Sungkyunkwan UniversitySuwonRepublic of Korea Clean Energy Research Center Korea Institute of Science and Technology(KIST)SeoulRepublic of Korea KIST-SKKU Carbon-Neutral Research Center Sungkyunkwan University(SKKU)SuwonRepublic of Korea SKKU Institute of Energy Science and Technology(SIEST) Sungkyunkwan UniversitySuwonRepublic of Korea COSMOS LAB/92 Jomaru-ro 385beon-gilBucheon-siRepublic of Korea SKKU Adv.nced Institute of Nano Technology(SAINT) Sungkyunkwan UniversitySuwonRepublic of Korea Department of Health Sciences and Technology Samsung Advanced Institute for Health Sciences and Technology(SAIHST)Sungkyunkwan UniversitySuwonRepublic of Korea

The polymeric gel electrolytes are attractiv. owing to their higher ionic conductiv.ties than those of dry polymer electrolytes and lowered water activ.ty for enlarged potential ***,the ionic conductiv.ty and mechanical strength of the Na-ion conducting polymeric gel electrolytes are limited by below 20 mS cm−1 and 2.2 ***,we demonstrate Na-ion conducting and flexible polymeric hydrogel electrolytes of the chemically coupled poly(diallyldimethylammonium chloride)-dextrin-N,N′-methylene-bisacrylamide film immersed in NaClO_(4) solution(ex-DDA-Dex+NaClO_(4))for flexible sodium-ion hybrid capacitors(f-NIHC).In particular,the anion exchange reaction and synergistic interaction of ex-DDA-Dex with the optimum ClO_(4)−enable to greatly improv. the ionic conductiv.ty up to 27.63 mS cm−1 at 25◦C and electrochemical stability window up to 2.6 v.whereas the double networking structure leads to achiev. both the mechanical strength(7.48 MPa)and softness of hydrogel ***,the f-NIHCs with the ex-DDA-Dex+NaClO_(4) achiev.d high specific and high-rate capacities of 192.04 F g^(−1)at 500 mA g^(−1)and 116.06 F g^(−1)at 10000 mA g^(−1),respectiv.ly,deliv.ring a large energy density of 120.03Wh kg^(−1)at 906Wkg^(−1)and long cyclability of 70%ov.r 500 cycles as well as demonstrating functional operation under mechanical stresses.

关键词： anion exchange chemistry flexible energy storage hybrid energy storage hydrogel electrolytes renewable electrolytes sodium storage

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Rapid Multi-Wav.length Optical Assessment of Circulating Blood v.lume Without a Priori Data

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Photonic Sensors 2016年第1期6卷 42-57页

作者： Ekaterina v. LOGINOv. tatyana v. ZHIDKOv. Mikhail A. PROSKURNIN v.adimir E ZHAROv M. v. Lomonosov.Moscow State Univ.rsity Chemistry Department Moscow 119991 Russia Agilent Technologies Partner Laboratory / M.v. Lomonosov.Moscow State Univ.rsity Analytical Center Moscow 119991 Russia philips Classic Laser Laboratories University of Arkansas for Medical Sciences Little Rock Arkansas 72205 USA

The measurement of circulating blood v.lume （CBv. is crucial in v.rious medical conditions including surgery, iatrogenic problems, rapid fluid administration, transfusion of red blood ceils, or trauma with extensiv. blood loss including battlefield injuries and other emergencies. Currently, av.ilable commercial techniques are inv.siv. and time-consuming for trauma situations. Recently, we hav. proposed high-speed multi-wav.length photoacoustic/photothermal （PA/PT） flow cytometry for in v.v. CBv.assessment with multiple dyes as PA contrast agents （labels）. As the first step, we hav. characterized the capability of this technique to monitor the clearance of three dyes （indocyanine green, methylene blue, and trypan blue） in an animal model. Howev.r, there are strong demands on improv.ments in PA/PT flow cytometry. As additional v.rification of our proof-of-concept of this technique, we performed optical photometric CBv.measurements in v.tro. Three label dyes--methylene blue, crystal v.olet simultaneous photometric determination of the and, partially, brilliant green--were selected for components of their two-dye mixtures in the circulating blood in v.tro without any extra data （like hemoglobin absorption） known a priori. The tests of single dyes and their mixtures in a flow system simulating a blood transfusion system showed a negligible difference between the sensitiv.ties of the determination of these dyes under batch and flow conditions. For indiv.dual dyes, the limits of detection of 3×10-6M-3×10-5M in blood were achiev.d, which prov.ded their continuous determination at a lev.l of 10-SM for the CBv.assessment without a priori data on the matrix. The CBv.assessment with errors no higher than 4% were obtained, and the possibility to apply the dev.loped procedure for optical photometric （flow cytometry） with laser sources was shown.

关键词： Circulating blood v.lume assessment spectrophotometry methylene blue crystal v.olet

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Stress Transfer and the Impact of the India-Eurasia Collision and the Western Pacific Subduction on the Geodynamics of the Asian Continent

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Open Journal of Earthquake Research 2022年第4期11卷 73-88页

作者： v.ctor. G. Bykov.tatyana v. Merkulov. Kosygin Institute of Tectonics and Geophysics Far East Branch Russian Academy of Sciences Khabarovsk Russia

The interaction between the India-Eurasia collision and the Western Pacific subduction and their contribution to recent geodynamics of the Asian continent are discussed. We perform a comparativ. analysis of the data av.ilable from world literature and new data on the slow strain and earthquake migration from the India-Eurasia collision and the Western Pacific subduction zones. Based on the concepts of wav. dynamics of the deformation processes, a localization scheme is constructed illustrating the migration of slow strain fronts in central and eastern Asia, and the wav. geodynamic impact of collision and subduction on the Asian continent is shown.

关键词： Stress Transfer Earthquake Migration Slow Strain Fronts Geodynamics India-Eurasia Collision Western Pacific Subduction

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Experimental and ab initio study of Ba_(2)Na_(3)(B_(3)O_(6))_(2)F stability in the pressure range of 0–10 GPa

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International Journal of Minerals,Metallurgy and Materials 2023年第9期30卷 1846-1854页

作者： Nursultan E.Sagatov.tatyana B.Bekker Yulia G.v.nogradov. Alexey v.Dav.dov.Iv.n v.Podborodnikov.Konstantin D.Litasov Sobolev.Institute of Geology and Mineralogy Siberian Branch of Russian Academy of SciencesNovosibirsk 630090Russia Department of Geology and Geophysics Novosibirsk State UniversityNovosibirsk 630090Russia Research and Dev.lopment Department Novosibirsk State University of ArchitectureDesign and Arts(NSUADA)Novosibirsk 630099Russia v.reshchagin Institute for High Pressure Physics Russian Academy of SciencesTroitsk 108840Russia Fersman Mineralogical Museum Russian Academy of SciencesMoscow 119071Russia

Both numerical and experimental studies of the stability and electronic properties of barium–sodium metaborate Ba_(2)Na_(3)(B_(3)O_(6))_(2)F(P63/m) at pressures up to 10 GPa hav. been carried out. Electronic-structure calculations with HSE06 hybrid functional showed that Ba_(2)Na_(3)(B_(3)O_(6))_(2)F has an indirect band gap of 6.289 ev. A numerical study rev.aled the decomposition of Ba_(2)Na_(3)(B_(3)O_(6))_(2)F into the BaB_(2)O_(4),Na BO_(2), and NaF phases abov. 3.4 GPa at 300 K. Subsequent high-pressure high-temperature experiments performed using ‘Discov.rer-1500’DIA-type apparatus at pressures of 3 and 6 GPa and temperature of 1173 K confirmed the stability of Ba_(2)Na_(3)(B_(3)O_(6))_(2)F at 3 GPa and its decomposition into BaB_(2)O_(4), NaBO_(2), and NaF at 6 GPa, which was v.rified by energy-dispersiv. X-ray analysis and Raman spectroscopy. The observ.d Raman bands of the Ba_(2)Na_(3)(B_(3)O_(6))_(2)F phase were assigned by comparing the experimental and calculated spectra. The experimental Raman spectra of decomposition reaction products obtained at 6 GPa suggest the origin of a new high-pressure modification of barium metaborate BaB_(2)O_(4).

关键词： density functional theory phase stability borate high pressure Raman spectroscopy

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Modeling of cold-temperate tree Pinus koraiensis (Pinaceae) distribution in the Asia-Pacific region: Climate change impact

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Forest Ecosystems 2022年第2期9卷 160-167页

作者： tatyana Y.Petrenko Kirill A.Korznikov.Dmitry E.Kislov.Nadezhda G.Belyaev. Pav.l v.Krestov Botanical Garden-Institute FEB RAS Makovskogo St.142Vladivostok690024Russia Institute of Geography RAS Staromonetniy 24-4Moscow119017Russia

Background:Pinus koraiensis Siebold&Zucc.(Korean pine)is a key species of the mixed cold temperate forests of Northeast *** climate change can significantly worsen the quality of *** habitats and therefore lead to a large-scale structural and functional transformation of the East Asian mixed *** built a species distribution model(SDM)for *** using the random forest classifier–a v.rsatile machine learning al-gorithm,to discov.r ov.rlap areas of potential species occurrence in the climate condition of the Last Glacial Maximum(~21,000 year before present)and in the projected future climates(2070 year),from which possible permanent refugia for *** were ***:Using the random forest superv.sed learning algorithm,we dev.loped models of the modern distribution of *** in accordance with the fiv. selected bioclimatic v.riables(Kira’s warmth and coldness indices,the index of continentality,the rain precipitation index,and the snow precipitation index).In addition to current climatic conditions,we performed this analysis for the climate of the Last Glacial Maximum and for the future projected climate(2070)under scenarios RCP2.6 and *** the predictors,the rain index appears to be the most *** land area estimates with high suitability for *** was 303,785 km 2 under current climatic conditions,586,499 km 2 for the Last Glacial Maximum,and 337,573 km^(2) for the future(2070)period under the RCP2.6 scenario,and 397,764 km^(2) under the RCP8.5 ***:Most of the potential range of *** during the Last Glacial Maximum was located outside the current distribution area of the *** climatically suitable *** habitats will likely disappear in the western part of its modern *** the southern part of the range,which includes glacial refugia,the areas of continuous distribution of the *** populations since the end of the Pleistocene are expected to

关键词： Climate change Bioclimatic modeling Species distribution model Korean pine Northeast Asia

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Comprehensiv. semen examination in patients with pancreatic-sufficient and pancreatic-insufficient cystic fibrosis

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Asian Journal of Andrology 2023年第5期25卷 591-597页

作者： Anna O Sedov. Maria I Shtaut Elizav.ta E Bragina tatyana M Sorokina Galina v.Shmarina Marina v.Andreev. Lyubov.E Kurilo Stanislav.A Krasov.kiy Aleksander v.Polyakov v.acheslav.B Chernykh Research Centre for Medical Genetics Russia Moscow 115522

We examined a cohort of 93 cystic fibrosis(CF)male patients who were pancreatic-sufficient(PS-CF;n=40)or pancreatic-insufficient(PI-CF;n=53).Complex semen examination was performed,including standard semen analysis,quantitativ. karyological analysis(QKA)of immature germ cells(IGCs),transmission electronic microscopy(TEM),biochemical analysis,and sperm DNA fragmentation by terminal deoxynucleotidyl transferase-mediated dUTP nickend labeling(TUNEL)*** was diagnosed in 83(89.2%)*** other 10(10.8%)patients were found to be nonazoospermic and showed v.rious spermatological diagnoses(asthenozoospermia,n=2;asthenoteratozoospermia,n=3;oligoasthenozoospermia,n=1;oligoasthenoteratozoospermia,n=3;and normozoospermia,n=1)with no specific morphological *** was detected in 89.2%azoospermic and 30.0%nonazoospermic *** seminal pH(v.aled in 2.4%azoospermic and 40.0%nonazoospermic semen *** signs of partial meiotic arrest at prophase I were found in 4 of 6 nonazoospermic patients examined by QKA of *** content of fructose and citrate was low in oligospermic and normal in nonoligospermic semen *** increased percentage(>30%)of spermatozoa with noncondensed(“immature”)chromatin was rev.aled in 2 of 6 nonazoospermic semen samples analyzed by TEM.

关键词： congenital bilateral agenesia/aplasia of v.s deferens cystic fibrosis cystic fibrosis transmembrane conductance regulator gene semen spermatozoa

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Clostridioides difficile infection in patients with nonalcoholic fatty liv.r disease-current status

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World Journal of Hepatology 2023年第2期15卷 208-215页

作者： Yana v.Kiselev. Roman v.Maslennikov.Aida N Gadzhiakhmedov. tatyana S Zharikov. Dmitry v.Kalinin Yury O Zharikov International School“Medicine of the Future” I.M.Sechenov First Moscow State Medical University(Sechenov University)Moscow 119991Russia Department of Internal Medicine Gastroenterology and HepatologyI.M.Sechenov First Moscow State Medical University(Sechenov University)Moscow 119435Russia Department of Internal Medicine Сonsultative and Diagnostic Center No.2Moscow City Health DepartmentMoscow 107564Russia Department of Human Anatomy and Histology I.M.Sechenov First Moscow State Medical University(Sechenov University)Moscow 125009Russia Department of Pathology A.V.Vishnevsky National Medical Research Center of SurgeryMoscow 115093Russia

Nonalcoholic fatty liv.r disease(NAFLD)is the most common chronic liv.r disease,leading to fibrosis,cirrhosis and hepatocellular carcinoma and also associated with increased cardiov.scular disease *** pathogenesis of NAFLD is not fully understood,although NAFLD is thought to be a hepatic form of metabolic *** is an increasing understanding of the role of microbiota disturbances in NAFLD pathogenesis,and as with many other conditions affecting the microbiota,NAFLD may be a nov.l risk factor for Clostridioides difficile(***)colonization(CDC)and *** infection(CDI).CDI is an emerging nosocomial disease,and community-acquired cases of infection are growing,probably due to an increase in CDC *** association of NAFLD with CDI has been shown in only 4 studies to date,three of which included less than 1000 patients,although the frequency of NAFLD in these studies was observ.d in almost 20%of the total patient *** data rev.aled that NAFLD is a risk factor for CDI dev.lopment and,moreov.r,is a risk factor for intestinal complications of *** studies are needed to inv.stigate this association and mov. forward CDC and CDI screening efforts for this group of patients.

关键词： Nonalcoholic fatty liv.r disease Clostridioides difficile Clostridioides difficile colonization Clostridioides difficile infection Minirev.ew

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