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Chk1防止DNA损伤的S期肿瘤细胞进行异常的有丝分裂
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科学通报 2009年 第22期54卷 2797-2805页
作者： 李小方 tarsha ward 姚雪彪 吴家睿 中国科学技术大学合肥微尺度物质科学国家实验室(研究部)中国科学技术大学生命科学学院系统生物学系 安徽合肥230027 Morehouse School of Medicine Department of PhysiologyAtlantaGA 30310USA 中国科学院系统生物学重点实验室中国科学院上海生命科学研究院生物化学与细胞生物学研究所 上海200031
为探讨在p53失活的肿瘤细胞中DNA甲基化试剂引发的DNA损伤对于细胞周期的影响,我们将同步化在G1,S和G2/M期的HeLa细胞分别进行甲磺酸甲酯(MMS)处理.MMS的处理结果表明,各个时相的细胞周期进程均发生延迟或阻滞,其中S期细胞对药物最为敏... 详细信息
来源： 维普期刊数据库 维普期刊数据库 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 同方期刊数据库 同方期刊数据库 评论
Aurora A orchestrates entosis by regulating a dynamic MCAK-TIP150 interaction
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Journal of Molecular Cell Biology 2014年 第3期8卷 240-254页
作者： PengXia JinhuaZhou Xiaoyu Song BingWu XingLiu Di Li Shuyuan Zhang Zhikai Wang H uijuan Yu tarsha ward Jiancun Zhang Yinmei Li Xiaoning Wang YongChen Zhen Guo Xuebiao Yao Anhui Key Laboratory of Cellular Dynamics & Chemical Biology Department of Optics and Optical Engineering and Hefei National Laboratory for Physical Sciences at Nanoscale University of Science and Technology of China Hefei 230027 China Molecular Imaging Center Atlanta Clinical and Translational Science Institute Morehouse School of Medicine Atlanta GA 30310 USA Harvard Medical School Boston MA 02115 USA Guangzhou Institutes of Biomedicine and Health Guangzhou 510513 China The 301 Hospital Beijing 100039 China Xijing Hospital The Fourth Military Medical University Xi'an 710032 China
Entosis, a ceU-in-ceU process, has been implicated in the formation of aneuploidy associated with an aberrant cell division control. Microtubule plus-end-tracking protein TI P150 facilitates the loading of MCAK onto t... 详细信息
来源： 维普期刊数据库 维普期刊数据库 评论
Mitotic motor CENP-E cooperates with PRC1 in temporal control of central spindle assembly
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Journal of Molecular Cell Biology 2020年 第8期12卷 654-665页
作者： Xu Liu Leilei Xu Junying Li Phil Y.Yao Wanjuan Wang Hazrat Ismail Haowei Wang Bryce Liao Zhihong Yang tarsha ward Ke Ruan Jianchun Zhang Quan Wu Ping He Xia Ding Dongmei Wang Chuanhai Fu Zhen Dou Feng Yan Wenwen Wang Xing Liu Xuebiao Yao MOE Key Laboratory for Cellular Dynamics&Anhui Key Laboratory for Chemical Biology CAS Center for Excellence in Molecular Cell ScienceHefei National Science Center for Physical Sciences at Microscale&University of Science and Technology of ChinaHefei 230027China Department of Physiology Morehouse School of MedicineAtlantaGA 30310USA School of Basic Medical Sciences Beijing University of Chinese MedicineBeijing 100029China Department of Biology Duke University DurhamNC 27708USA Institute of ProteoGenomics Beijing 100029China Harvard Medical School BostonMA 02115USA
Error-free cell division depends on the accurate assembly of the spindle midzone from dynamic spindle microtubules to ensure chromatid segregation during metaphase-anaphase ***,the mechanism underlying the key transit... 详细信息
来源： 维普期刊数据库 维普期刊数据库 评论
Methylation of PLK1 by SET7/9 ensures accurate kinetochore–microtubule dynamics
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Journal of Molecular Cell Biology 2020年 第6期12卷 462-476页
作者： Ruoying Yu Huihui Wu Hazrat Ismail Shihao Du Jun Cao Jianyu Wang tarsha ward Fengrui Yang Ping Gui Mahboob Ali Lingluo Chu Fei Mo Qi Wang Youjun Chu Jianye Zang Yun Zhao Mingliang Ye Guowei Fang Peng RChen Zhen Dou Xinjiao Gao Wenwen Wang Xing Liu Xuebiao Yao MOE Key Laboratory for Cellular Dynamics&Anhui Key Laboratory for Chemical Biology CAS Center for Excellence in Molecular Cell ScienceHefei National Science Center for Physical Sciences at Microscale&University of Science and Technology of ChinaHefei 230027China BUCM-MSM-USTC Joint Program on Global Health Equity Beijing University of Chinese MedicineBeijing 100029China Department of Physiology Morehouse School of MedicineAtlantaGA 30310USA Harvard Medical School BostonMA 02115USA Dalian Institute for Physical Chemistry Dalian 116023China Shanghai Institute of Biochemistry and Cell Biology Center for Excellence in Molecular Cell ScienceChinese Academy of SciencesShanghai 200031China College of Chemistry and Molecular Engineering Peking UniversityBeijing 100871China
Faithful segregation of mitotic chromosomes requires bi-orientation of sister chromatids, which relies on the sensing of correct attachments between spindle microtubules and kinetochores. Although the mechanisms under... 详细信息
来源： 维普期刊数据库 维普期刊数据库 评论
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