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Advances in Chemical Engineering and Science 2024年第2期14卷 74-83页

作者： Walther B. Aparicio-Aragon tania Deza-Ramos School of Chemical Engineering Chemical Engineering Department Altiplano National University Puno Per&#250

Currently a technique widely used for gold extraction is mercury by amalgamation technique, the tailing produced pollutes water of all kinds, so it is necessary to develop a form of selective mitigation, for which it is necessary to use complexing agents based on calixarene functionalized with mercury sequestering agents. These are immobilized by adding supports based on natural silica to form polymers and make them insoluble in all types of solvents, so that they can be used as an extractor and at the same time regenerate to their original properties for continuous reuse.

关键词： Extraction Amalgamation Polymer Natural Silicate Calixarene

股票市场对新冠疫情的反应——来自印度尼西亚大规模社交限制政策的经验证据

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股票市场对新冠疫情的反应——来自印度尼西亚大规模社交限制政策...

作者： tania Hambali（何玉玲）天津大学

学位级别：硕士

本文旨在以Covid-19大流行和印尼资本市场反应为中心进行实证研究。本文的目的是利用异常收益率(AR)计算来确定各个行业股票价格的初始和最终差异,并在政府立即采取行动颁布该法案前后,找出印度尼西亚证券交易所(IDX)上市股票交易量活动... 详细信息

本文旨在以Covid-19大流行和印尼资本市场反应为中心进行实证研究。本文的目的是利用异常收益率(AR)计算来确定各个行业股票价格的初始和最终差异,并在政府立即采取行动颁布该法案前后,找出印度尼西亚证券交易所(IDX)上市股票交易量活动(TVA)中的异常情况首都雅加达的大规模社会限制政策。采用事件研究法(ESM)进行假设检验,并提供支持性证据。二级定量数据来源于在证券交易所上市的股票的收盘价和交易量,事件期从2019年10月11日开始至2020年7月14日。该数据通过使用统计软件Stata/MP进行配对差异t检验分析,通过对各行业的进一步分析,给出了各行业在一定时间间隔内的平均异常收益率、累计异常收益率和交易量活动值。样本选取过程采用立意抽样法,共有652家公司在交易所内上市,按照JASICA行业指数分类,进一步将其分为9个行业指数。结果表明,印尼资本市场对该事件的反应是负面的,表明投资活动受到了LSSR的影响。除了持续的大流行爆发之外,这一事件似乎还造成了投资者信心的短期下降,从而导致了综合板块的下跌。差异敏感性检验发现,在事件窗口期间,除农业部门外,所有部门的平均异常回报率都存在显著差异。TVA的情况则相反,其结果并未表明所有行业的交易量活动存在显著差异。为了对各行业指数的表现进行正式的实证分析,笔者分别计算了一定区间内的平均异常收益率、累计异常收益率和交易量活跃度。基于这一计算,笔者发现,虽然交易量活跃度(TVA)的值为正,但结果没有显著差异。对具体行业的分析也表明,在非正常收益方面,消费品行业价值最高,金融行业价值最低。就交易量活动而言,杂项行业的价值最低,采矿业的结果显示价值最高。由于Covid-19的研究处于前沿研究领域;无论是为了得出结论和相关性,还是为了公众的利益提供未来的建议,笔者希望本研究能够对投资者或印尼资本市场参与者有所帮助,尤其是对那些将从行业角度分析股票的投资者。股票是流动的;从长远来看,它们可以资本化并盈利。然而,由于意外消息而波动的可能性仍然很大。提醒投资者,要多关注公共卫生政策,逻辑思维,多做逻辑决策,不受情绪影响。资产管理公司和其他金融机构也应制定更大范围的应急计划,并调整其投资策略,以适应“新常态”和其他未来可能发生的冲击事件。建议今后可以更多地尝试调查行业对全球市场的影响,以便纳入,同时增加更多的变量,使用其他具有最新数据的计算模型。作者还鼓励未来的研究人员发展和创造一个综合的流行病学和经济学方法,以评估传染病的危险因素。

关键词： 2019年冠状病毒病(COVID-19) 印度尼西亚证券交易所行业级股票收益率交易量活动大规模社会限制(LSSR) 事件研究

Correlations between age, Charlson score and outcome in clinical unilateral T3a prostate cancer

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Asian Journal of Andrology 2009年第1期11卷 131-137页

作者： Chao-Yu Hsu Steven Joniau Raymond Oyen tania Roskams Hein Van Poppel Department of Urology Department of Radiology Department of Histopathology University Hospitals KULeuven Leuven 3000 Belgium

According to the European Association of Urology （EAU） guidelines, a life expectancy of〉 10 years is considered an important factor in the treatment of prostate cancer. The Charlson score is used to predict mortality based on comorbidities. The purpose of this study was to investigate the relationship between age, Charlson score and outcome in patients with cT3a prostate cancer. Between 1987 and 2004, 200 patients, who were with clinical T3a prostate cancer and who underwent radical prostatectomy （RP）, were previously detected by digital rectal examination （DRE）. Patients were categorized into two age groups （〈 65 and≥65 years old）. Patients were also divided into two groups according to Charlson score （ = 0 and ≥ 1）. Both age and Charlson score were analyzed regarding their predictive power of patients＇ outcomes. The mean follow-up period was 70.6 months, and the mean age of patients was 63.3 years. In all, 106 patients were 〈 65 years old and 94 patients were ≥65 years old. Age was a significant predictor of overall survival （OS）. A Charlson score of 0 was found in 110 patients, and of ≥ 1 in 90 patients. Charlson score was not a significant predictor of biochemical progression-free survival （BPFS）, clinical progression-free survival （CPFS） or OS. Cox multivariate analysis showed that margin status was a significant independent factor in BPFS, and cancer volume was a significant independent factor in CPFS. Charlson score does not influence the outcome in patients with clinical locally advanced prostate cancer. Age may influence OS. RP can be performed in motivated healthy older patients. However, the patients need to be counseled regarding possible surgery-related side effects, such as urinary incontinence and erectile dysfunction, which are age- and comorbidity-dependent.

关键词： age Charlson score cT3a prostate cancer

Intestinal complications in Brazilian patients with ulcerative colitis treated with conventional therapy between 2011 and 2020

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World Journal of Gastroenterology 2023年第8期29卷 1330-1343页

作者： Adalberta Lima Martins Rodrigo Galhardi Gasparini Ligia Yukie Sassaki Rogerio Saad-Hossne Alessandra Mileni Versut Ritter tania Biatti Barreto Taciana Marcolino Claudia Yang Santos Espirito Santo Health Office State Office for Pharmaceutical AssistanceEspirito Santos 29056-030Brazil Department of Gastroenterology Specialized Medical CenterMarília 17502-020Brazil Department of Gastroenterology Sao Paulo State UniversityMedical SchoolBotucatu 18618-687Brazil Real World Evidence IQVIA BrazilSao Paulo 04719-002Brazil Department of Gastroenterology Takeda Pharmaceuticals BrazilSao Paulo 04794-000Brazil

BACKGROUND This was an observational, descriptive, and retrospective study from 2011 to 2020 from the Department of Informatics of the Brazilian Healthcare System *** To describe the intestinal complications(IC) of patients with ulcerative colitis(UC) who started conventional therapies in Brazil’s public Healthcare *** Patients ≥ 18 years of age who had at least one claim related to UC 10th revision of the International Statistical Classification of Diseases and Related Health Problems(ICD-10) code and at least 2 claims for conventional therapies were included. IC was defined as at least one claim of: UC-related hospitalization, procedures code for rectum or intestinal surgeries, and/or associated disease defined by ICD-10 codes(malignant neoplasia of colon, stenosis, hemorrhage, ulcer and other rectum or anus disease, megacolon, functional diarrhea volvulus, intussusception and erythema nodosum). Descriptive statistics, annual incidence, and incidence rate(IR) [per 100 patient-years(PY)] over the available follow-up period were *** In total, 41229 UC patients were included(median age, 48 years;65% women) and the median(interquartile range) follow-up period was 3.3(1.8-5.3) years. Conventional therapy used during follow-up period included: mesalazine(87%), sulfasalazine(15%), azathioprine(16%) or methotrexate(1%) with a median duration of 1.9(0.8-4.0) years. Overall IR of IC was 3.2 cases per 100 PY. Among the IC claims, 54% were related to associated diseases, 20% to procedures and 26% to hospitalizations. The overall annual incidence of IC was 2.9%, 2.6% and 2.5% in the first, second and third year after the first claim for therapy(index date), respectively. Over the first 3 years, the annual IR of UC-related hospitalizations ranged from 0.8% to 1.1%;associated diseases from 0.9% to 1.2%-in which anus or rectum disease, and malignant neoplasia of colon were the most frequently reported;and procedure events from 0.6% to 0.7%, bein

关键词： Ulcerative colitis Brazil Conventional therapy Intestinal complications Real world Public healthcare

Intravascular infusion of autologous delipidated plasma induces antiatherogenic lipoproteins and causes regression of atherosclerosis <br>—Studies in non-primates, monkeys and humans

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Health 2013年第7期5卷 19-33页

作者： Bill E. Cham tania R. Chase Vanuatu Research Centre Port Vila The Republic of Vanuatu

Atherosclerosis is the primary pathophysiological cause of heart disease and cerebrovascular disease. It is responsible for more than 20% of deaths worldwide each year. Treatments for atherosclerosis may include lifestyle changes, drugs, and medical procedures or surgery. There is a need for a rapid and effective treatment for this disease. In 1976, it was hypothesized that a multifunctional plasma delipidation process when applied to hyperlipidemic patients would lead to rapid regression of atherosclerosis. The procedure has now been applied to a variety of non-primates, primates and humans. In all models studied, large quantities of antiatherogenic lipoprotein particles were generated that led to the mechanisms of reverse cholesterol transport. Trends to regression and actual regression of atherosclerosis have now been reported using a specific plasma delipidation process consisting of lipid extraction from plasma with mixtures of butanol and ethers.

关键词： Atherosclerosis Delipidation Regression Pre-β HDL Delipidated LDL

Biofiltration of Nitrous Oxide Using Cow-Manure Based Compost as Medium Filter

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Journal of Environmental Protection 2012年第7期3卷 584-588页

作者： tania Surya Utami Heri Hermansyah Mohamad Nasikin Department of Chemical Engineering Faculty of Engineering Universitas Indonesia Depok Indonesia

Nitrous oxide (N2O) gas is a fourth contributor in the greenhouse effect after CO2, CH4, and water vapor. Although its concentration is relatively low, but very difficult to be decomposed in the atmosphere. A laboratory-scale biofilter was used to evaluate the effects of flow rate, medium depth, and water content of filter medium on the N2O removal efficiency and the growth of microorganisms in the compost. The biofilter was operated using cow-manure based compost medium with husk and coco peat as bulking agent. Research was carried out by batch flow system for 9 hours. The result indicates that the highest N2O removal efficiency is obtained under flow rate of 88 cm3/min with a depth of 50 cm and water content 50% (w/w) by 61%, and elimination capacity for 14078 g/(m3·h) was achieved.

关键词： Biofilter Compost Cow-Manure Nitrous Oxide Removal Efficiency

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CLIL在高级汉语综合课教学的应用

CLIL在高级汉语综合课教学的应用

作者： ANDREA tania BAKTI（林敏芳）华中师范大学

学位级别：硕士

随着国际的全球化以及中国经济的飞速发展导致目前的地位不断提升。中国的汉语作为世界上使用人口最多的语言,目前学习者的人数急剧增加。面对这个现象,对外汉语教学界需要提供汉语学习者相当的汉语教学服务。在对外汉语教学界,综合课... 详细信息

随着国际的全球化以及中国经济的飞速发展导致目前的地位不断提升。中国的汉语作为世界上使用人口最多的语言,目前学习者的人数急剧增加。面对这个现象,对外汉语教学界需要提供汉语学习者相当的汉语教学服务。在对外汉语教学界,综合课是汉语教学不可缺少的一门课程。它包含了语言交际能力的培养,以及中国文化的知识。高级阶段的汉语学习者需要学习更高层的交际能力,以及更多更复杂的中国文化内容。目前的高级综合课教学仍然使用以教师讲授为主的教学法,导致综合语言技能的训练不够充分,文化内容的传授也不够充分。因此,需要不同的教学方法来处理高级阶段的综合课。觉悟到以上的现象,笔者尝试使用CLIL(Content Language Integrated Learning,内容-语言融合学习)进行高级汉语综合课的教学。CLIL是两焦点的教学法,同时关注到语言和内容的教学。本文共分为五章。第一章主要描述研究缘起、研究意义和目标、相关研究综述、研究方法以及论文结构。第二章为CLIL的内涵、CLIL的主要特征以及对高级汉语综合课的价值分析。第三章着重基于第二章的理论做出针对高级汉语综合课的教学方案。第四章为CLIL在高级汉语综合课真实教学中的应用,包括描述案例教学实践、教学实践的实施情况以及对此实践进行教学反思和建议。本章对课堂教学的观察记录和问卷调查作出简要的描述与分析。第五章为结语部分,对本文所研究的问题做出总结,最后提出了后续的研究展望。

关键词： CLIL 内容-语言融合学习教学法综合课

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丝绸手绘在服装设计中的应用

丝绸手绘在服装设计中的应用

作者： tania TANG YUN SING 北京工业大学

学位级别：硕士

丝绸手绘是中国历史悠久的一种装饰工艺,其艺术价值在多体现在服饰品以及室内家纺装饰品之中,在绘画工艺与材料的制作上,具有美观与实用的装饰艺术价值受到了公众的喜爱。随着经济的发展,科技不断进步,以及人们审美与消费水平的提高,丝... 详细信息

丝绸手绘是中国历史悠久的一种装饰工艺,其艺术价值在多体现在服饰品以及室内家纺装饰品之中,在绘画工艺与材料的制作上,具有美观与实用的装饰艺术价值受到了公众的喜爱。随着经济的发展,科技不断进步,以及人们审美与消费水平的提高,丝绸手绘服装制品并没有真正步入时尚流行,在市场销售和产品审美中渐渐退出了人们的视线。其中的因素很多,如:图案以花鸟和人物及传统纹样居多,缺少现代装饰设计艺术的时尚魅力和主题创意;绘画以工笔和写意表现形式为主,缺少现代绘画艺术设计手法;服饰产品风格单一,缺乏时尚装饰设计;形制类别过于传统,缺乏艺术创新设计;画面色彩纯度较高,缺乏和谐度等问题原因,迫使丝绸手绘的装饰性,需要与当代时尚艺术的审美情趣同步发展。如何挖掘手绘装饰艺术的丰富性与时尚魅力的艺术风格,使得丝绸手绘在服装设计装饰应用更具现代时尚艺术魅力,是本课题研究的意义和价值。以丝绸手绘设计表现研究对象,本课题通过对材料、装饰题材、绘画风格、色彩搭配、艺术表现形制和主题故事等,综合多种手绘手法,为丝绸手绘的装饰艺术在服装设计中展现独特风格之路。

关键词：丝绸手绘工艺技法装饰表现

Dissecting Emerging Aspects of Regulatory Circuitry in Man and Mice: Regulatory T Cell Biology

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Advances in Bioscience and Biotechnology 2018年第9期9卷 443-468页

作者： tania Rahman Md. Ferdous Seraj Annelise Casellato Department of Biochemistry and Molecular Biology Bio21 Molecular Science and Biotechnology Institute University of Melbourne Melbourne Australia Department of Microbiology and Immunology University of Melbourne at the Peter Doherty Institute for Infection and Immunity Melbourne Australia School of Civil Environmental and Chemical Engineering RMIT University Melbourne Australia Departamento de Química Inorganica Instituto de Química Universidade Federal do Rio de Janeiro Rio de Janeiro Brazil

Regulatory T cells (Treg), a component of adaptive immunity, are well known for their immunosuppressive roles and their ability to maintain the balance between the immunological and pathological reactions. Treg have been shown to provide protective responses and their depletion has resulted severe pathology in some pathogen infections. The work presented here has unravelled the potential of regulatory cells in the immune system including different repertoir of Treg cell subsets, markers to distinguish them, Treg suppression mechanisms in the pathogenesis of various infections and summarize different mouse models depleting Tregs. These findings would help set up future avenues of research to elucidate a key mechanism of action of these cells and provide new therapeutic insights for pathogenesis and also for broader antibacterial/antiviral/antiproliferative immunity.

关键词： Regulatory T Cells Foxp3 tTreg pTreg IL-10 TGF-β Helios Neuropilin-1

Cabazitaxel in castration resistant prostate cancer with brain metastases: 3 case reports

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World Journal of Clinical Cases 2014年第6期2卷 228-231页

作者： Sabino De Placido Pasquale Rescigno Piera Federico Carlo Buonerba Davide Bosso Livio Puglia Michela Izzo tania Policastro Giuseppe Di Lorenzo Genitourinary Cancer Section Medical Oncology Department of Clinical Medicine Federico Ⅱ University

Prostate cancer is the most common non-cutaneous malignancy for men. The skeleton is the most common metastatic site but, following an improvement in survival, metastases in uncommon sites are being found more frequently in clinical practice, especially brain metastases. Despite the new drugs now available for metastatic castration resistant prostate cancer, no clinical evidence exists about their effectiveness on brain metastases. We describe the clinical history of 3 patients treated with cabazitaxel plus whole brain radiotherapy. These case reports demonstrate that cabazitaxel is highly active and well tolerated in brain metastases.

关键词： Cabazitaxel Brain metastases Prostate cancer