检索结果-南通市图书馆

Changing Patterns of Mortality in Viral Hepatitis——China,1987–2021

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China CDC weekly 2023年第42期5卷 933-937页

作者： Chen Chen zuliyaer talifu Yu Wu Binbin Su Wanwei Dai Department of Population health and Aging science School of Population Medicine and Public HealthChinese Academy of Medical Science&Peking Union Medical CollegeBeijingChina School of Population Medicine and Public Health Chinese Academy of Medical Science&Peking Union Medical CollegeBeijingChina Department of Health economics School of Population Medicine and Public HealthChinese Academy of Medical Science&Peking Union Medical CollegeBeijingChina Office of Academic Research of Peking University Third Hospital BeijingChina

Summary What is already known about this topic?Viral hepatitis continues to present a major global public health challenge,with China shouldering the heaviest burden of this disease *** is added by this report?This study examined evolving trends and assessed the impacts of age,period,and cohort on viral hepatitis mortality from 1987 to 2021 in both urban and rural settings across *** are the implications for public health practice?This research provides critical insights,enabling policymakers to develop precise and effective intervention strategies that are specifically tailored to address the needs of high-risk older adults.

关键词： mortality precise policy

Age,Sex,and Disease-Specific Mortality Contributions to Life Expectancy in Urban and Rural China,1987–2021

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China CDC weekly 2024年第28期6卷 684-688,I0001页

作者： zuliyaer talifu Chen Chen Xinran Shen Panliang Zhong Yanan Luo Binbin Su Department of Population Health and Aging Science School of Population Medicine and Public HealthChinese Academy of Medical Sciences/Peking Union Medical CollegeBeijingChina School of Population Medicine and Public Health Chinese Academy of Medical Sciences/Peking Union Medical CollegeBeijingChina Department of Global Health School of Public HealthPeking UniversityBeijing100191China

What is already known about this topic?Over the past several decades,China has experienced substantial improvements in life expectancy(LE),signifying major advancements in public health *** is added by this report?This study offers an in-depth analysis of the contributions made by various diseases and age demographics to the growth of LE in China over the past 35 years,highlighting crucial factors that influence population *** are the implications for public health practice?The results highlight the need for interventions tailored to various disease types and age groups in order to enhance LE and improve public health *** health strategies should prioritize disease prevention,control initiatives,and enhancements in healthcare services that are specifically designed to meet the needs of distinct population demographics.

关键词： Rural Urban prevention

A Multi-State Model Study of the Disability-Free Life Expectancy Among Older Adults with Chronic Multimorbidity Based on CHARLS—China,2011–2020

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China CDC weekly 2024年第28期6卷 695-698,I0002页

作者： Shan Yang Panliang Zhong Xinran Shen Binbin Su zuliyaer talifu Shuai Guo Xiaoying Zheng Department of Population Health and Aging Science School of Population Medicine and Public HealthChinese Academy of Medical Sciences/Peking Union Medical CollegeBeijingChina School of Population Medicine and Public Health Chinese Academy of Medical Sciences/Peking Union Medical CollegeBeijingChina APEC Health Science Academy Peking UniversityBeijingChina

What is already known about this topic?Chronic disease multimorbidity is prevalent among older Chinese people,seriously affecting their wellbeing and quality of *** is added by this report?This study estimated the impact of multimorbidity on the risk of health state transitions and health expectancy among older adults in *** used population-representative,long-term longitudinal data and multi-state Markov modeling along with microsimulation *** are the implications for public health practice?The study results suggest that the Chinese government should strengthen the prevention and management of multimorbidity and accelerate the transition from chronic disease management to multimorbidity management.

关键词： among prevention morbidity

Changing Patterns of Injury Mortality Among the Elderly Population in Urban and Rural Areas—China,1987–2021

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China CDC weekly 2023年第51期5卷 1140-1144页

作者： Yu Wu Lin Bai zuliyaer talifu Jiatong Gao Chengfu Li Fei Wu Xiaoying Zheng Department of Population Health and Aging Science School of Population Medicine and Public HealthChinese Academy of Medical Sciences/Peking Union Medical CollegeBeijingChina Department of Health Economics School of Population Medicine and Public HealthChinese Academy of Medical Sciences/Peking Union Medical CollegeBeijingChina Center for Aging Science and Health Development Research School of Population Medicine and Public HealthChinese Academy of Medical Sciences/Peking Union Medical CollegeBeijingChina China Population and Development Research Center BeijingChina Department of Physical Education and Research Peking UniversityBeijingChina APEC Health Science Academy(HeSAY) Peking UniversityBeijingChina.

What is already known about this topic?Injury is a significant public health issue,particularly among the elderly ***,the extent of this problem varies significantly based on age,gender,and geographic *** is added by this report?This study aims to examine the changing patterns of injury mortality rates in China over a 35-year period and assess the age-period-cohort effects on mortality *** are the implications for public health practice?This study examines the evolving patterns of injury mortality in the elderly population and identifies potential high-risk *** findings offer valuable insights for informing injury prevention policies.

关键词： mortality prevention Rural

Association between brain N-acetylaspartate levels and sensory and motor dysfunction in patients who have spinal cord injury with spasticity:an observational case-control study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2023年第3期18卷 582-586页

作者： Jia-Yi Liu Ya-Jing Li Xin-Ying Cong zuliyaer talifu Xin Zhang Feng Gao Jian-Jun Li School of Rehabilitation Capital Medical UniversityBeijingChina Department of Spinal and Neural Function Reconstruction China Rehabilitation Research CenterBeijingChina China Rehabilitation Science Institute BeijingChina Beijing Key Laboratory of Neural Injury and Rehabilitation BeijingChina Center of Neural Injury and Repair Beijing Institute for Brain DisordersBeijingChina Rehabilitation Department Shanghai Huashan HospitalShanghaiChina Department of Medical Imaging China Rehabilitation Research CenterBeijingChina

Spinal cord injury is a severe and devastating disease,and spasticity is a common and severe complication that is notoriously refractory to ***,the pathophysiological mechanisms underlying spasticity and its development remain largely *** goal of the present study was to find differences,if any,in metabolites of the left precentral gyrus and basal ganglia of patients who have spinal cord injury with or without spasticity,and to explore the relationship between the brain metabolite concentrations and clinical ***-six participants were recruited for magnetic resonance spectroscopic examination:23 with spinal cord injury(12 with spasticity and 11 without spasticity)and 13 healthy *** acquired localized proton spectra from the precentral gyrus and basal ganglia via 10 mm^(3) ***,univariate linear regression analysis demonstrated that the lower that the N-acetylaspartate concentration(a marker for neuronal loss)was in the precentral gyrus of the patients,the lower their ASIA(American Spinal Injury Association)light-touch scores,pinprick scores,and motor ***,longer durations of injury were associated with higher N-acetylaspartate levels in the precentral *** with the healthy participants and patients without spasticity,N-acetylaspartate levels in the patients with spasticity were significantly lower in both the precentral gyrus and basal *** N-acetylaspartate levels also correlated with greater sensory and motor dysfunction in the patients who had spinal cord injury with spasticity.

关键词： ASIA motor score ASIA sensory score basal ganglia central nervous system duration of injury magnetic resonance spectroscopy N-acetylaspartate precentral gyrus spasticity spinal cord injury

In vivo astrocyte-to-neuron reprogramming for central nervous system regeneration:a narrative review

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2023年第4期18卷 750-755页

作者： zuliyaer talifu Jia-Yi Liu Yun-Zhu Pan Han Ke Chun-Jia Zhang Xin Xu Feng Gao Yan Yu Liang-Jie Du Jian-Jun Li School of Rehabilitation Capital Medical UniversityBeijingChina Department of Spinal and Neural Functional Reconstruction China Rehabilitation Research CenterBeijingChina Chinese Institute of Rehabilitation Science BeijingChina Center of Neural Injury and Repair Beijing Institute for Brain DisordersBeijingChina Beijing Key Laboratory of Neural Injury and Rehabilitation BeijingChina School of Rehabilitation Sciences and Engineering University of Health and Rehabilitation SciencesQingdaoShandong ProvinceChina

The inability of damaged neurons to regenerate within the mature central nervous system(CNS)is a significant neuroscientific *** are an essential component of the CNS and participate in many physiological processes including blood-brain barrier formation,axon growth regulation,neuronal support,and higher cognitive functions such as *** reprogramming studies have confirmed that astrocytes in the mature CNS can be transformed into functional *** on in vitro work,many studies have demonstrated that astrocytes can be transformed into neurons in different disease models to replace damaged or lost ***,many findings in this field are controversial,as the source of new neurons has been *** review summarizes progress in reprogramming astrocytes into neurons in vivo in animal models of spinal cord injury,brain injury,Huntington’s disease,Parkinson’s disease,Alzheimer’s disease,and other neurodegenerative conditions.

关键词： astrocyte astrocyte-to-neuron central nervous system in vivo nerve regeneration neurological disorders reprogramming review

Sodium selenite promotes neurological function recovery after spinal cord injury by inhibiting ferroptosis

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2022年第12期17卷 2702-2709页

作者： Yi-Xin Chen talifu zuliyaer Bin Liu Shuang Guo De-Gang Yang Feng Gao Yan Yu Ming-Liang Yang Liang-Jie Du Jian-Jun Li School of Rehabilitation Medicine Capital Medical UniversityBeijingChina China Rehabilitation Science Institute BeijingChina Center of Neural Injury and Repair Beijing Institute for Brain DisordersBeijingChina Department of Spinal and Neural Functional Reconstruction China Rehabilitation Research CenterBeijingChina Beijing Key Laboratory of Neural Injury and Rehabilitation BeijingChina Department of Rehabilitation Medicine Xiangya Hospital of Central South UniversityChangshaHunan ProvinceChina Department of Spine Surgery Hunan Provincial People’s Hospital(The First Affiliated Hospital of Hunan Normal University)ChangshaHunan ProvinceChina

Ferroptosis is a recently discovered form of iron-dependent cell death,which occurs during the pathological process of various central nervous system diseases or injuries,including secondary spinal cord *** has been shown to promote neurological function recovery after cerebral hemorrhage by inhibiting ***,whether selenium can promote neurological function recovery after spinal cord injury as well as the underlying mechanism remain poorly *** this study,we injected sodium selenite(3μL,2.5μM)into the injury site of a rat model of T10 vertebral contusion injury 10 minutes after spinal cord injury *** found that sodium selenite treatment greatly decreased iron concentration and levels of the lipid peroxidation products malondialdehyde and ***,sodium selenite increased the protein and mRNA expression of specificity protein 1 and glutathione peroxidase 4,promoted the survival of neurons and oligodendrocytes,inhibited the proliferation of astrocytes,and promoted the recovery of locomotive function of rats with spinal cord *** findings suggest that sodium selenite can improve the locomotive function of rats with spinal cord injury possibly through the inhibition of ferroptosis via the specificity protein 1/glutathione peroxidase 4 pathway.

关键词： ferroptosis glutathione peroxidase 4 glutathione iron lipid peroxidation neural regeneration secondary injury sodium selenite specificity protein 1 spinal cord injury

1990—2019年中国60岁及以上老年人疾病负担趋势分析

在线全文

学校读者我要写书评

暂无评论

中华疾病控制杂志 2024年第11期28卷 1321-1329,1343页

作者：魏欣悦祖力亚尔·塔力甫钟盼亮赵艺皓王云鹤郑晓瑛苏彬彬中国医学科学院北京协和医学院群医学及公共卫生学院人口健康与老龄科学系北京100730 英国牛津大学纳菲尔德人口健康系牛津OX37LF

目的分析1990—2019年中国≥60岁老年人疾病负担变化趋势。方法利用2019年全球疾病负担数据库提供的中国≥60岁老年人伤残调整寿命年数据,使用该数据库提供的世界人口数作为标准对其进行标化,采用Joinpoint对数线性回归模型计算平均年... 详细信息

目的分析1990—2019年中国≥60岁老年人疾病负担变化趋势。方法利用2019年全球疾病负担数据库提供的中国≥60岁老年人伤残调整寿命年数据,使用该数据库提供的世界人口数作为标准对其进行标化,采用Joinpoint对数线性回归模型计算平均年度变化百分比,检验其长期变化趋势,分析1990—2019年中国≥60岁老年人疾病负担变化趋势。结果1990—2019年中国≥60岁老年人一级病因疾病负担均呈下降趋势,其中传染病所造成的疾病负担下降幅度最大,从1990年的6079.32/10万下降到2019年的2056.84/10万;非传染性疾病是造成老年人疾病负担的首要原因,2019年为71694.02/10万。在三级病因中,结核病疾病负担下降幅度最大;2019年,脑卒中、缺血性心脏病和慢性阻塞性肺疾病,下呼吸道感染和结核病,跌倒、道路伤害和自杀分别是造成非传染性疾病、传染病和伤害疾病负担的主要原因。结论非传染性疾病和伤害日益成为中国急需解决的公共卫生问题。应加强对重点疾病(心脑血管疾病、恶性肿瘤、肌肉骨骼疾病等)以及重点人群(男性、≥85岁人群)的防控,通过管理健康风险因素及可改变的行为生活方式预防疾病发生,降低疾病负担。

关键词：老年人疾病负担伤残调整寿命年趋势分析

早期应用双膦酸盐类药物治疗脊髓损伤后骨质疏松效果的meta分析

在线全文

学校读者我要写书评

暂无评论

中华骨与关节外科杂志 2023年第5期16卷 446-452页

作者：柯涵刘武博祖力亚尔·塔力甫杜华勇潘韵竹张春佳胥鑫刘嘉义高峰杨德刚李建军山东大学齐鲁医学院济南250012 康复大学山东青岛266113 中国康复研究中心脊柱脊髓神经功能重建科北京100068 中国康复科学所北京100068 北京脑重大疾病研究院神经损伤与修复研究所北京100068 神经损伤与康复北京市重点实验室北京100068 首都医科大学康复医学院北京100068

目的:系统评价早期应用双膦酸盐类药物治疗脊髓损伤后骨质疏松的效果。方法:在PubMed、Cochrane Library、Embase、Web of Science、Sinomed、中国知网、万方数据、维普数据库中检索脊髓损伤后3个月内使用双膦酸盐类药物治疗的随机对照... 详细信息

目的:系统评价早期应用双膦酸盐类药物治疗脊髓损伤后骨质疏松的效果。方法:在PubMed、Cochrane Library、Embase、Web of Science、Sinomed、中国知网、万方数据、维普数据库中检索脊髓损伤后3个月内使用双膦酸盐类药物治疗的随机对照研究,提取资料并进行质量评价,使用Rev Man 5.4软件进行数据分析。结果:共纳入6项随机对照研究,共有170例患者完成12个月随访,双膦酸盐治疗组87例,对照组83例。Meta分析结果显示,与对照组相比,双膦酸盐组腰椎骨密度增加5.12%(95%CI:2.65~7.59,P<0.05),髋部骨密度增加15.49%(95%CI:13.50~17.49,P<0.05),Ⅰ型胶原C-末端肽交联(CTX)水平降低0.38 nmol/g(95%CI:-0.57~0.18,P<0.05)。膝部骨密度、Ⅰ型原胶原N-端前肽(PINP)、Ⅰ型胶原N-末端肽交联(NTX)、血钙水平,两组比较差异无统计学意义。结论:早期使用双膦酸盐类药物能够减少脊髓损伤患者腰椎、髋部骨吸收,改善部分骨代谢指标,安全性较高。

关键词：骨质疏松脊髓损伤双膦酸盐随机对照试验 Meta分析