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International Journal of Smart and Nano Materials 2016年第4期7卷 265-275页

作者： Fumio Narita takuya kobayashi Yasuhide Shindo Department of Materials Processing Graduate School of EngineeringTohoku UniversityAoba-yama 6-6-02SendaiJapan

This article studies the dielectric and piezoelectric behavior of unpoled and poled barium titanate(BaTiO_(3))polycrystals with oxygen vacancies.A phase field model is employed for BaTiO_(3) polycrystals,coupled with the time-dependent Ginzburg–Landau theory and the oxygen vacancies diffusion,to demonstrate the interaction between oxygen vacancies and domain *** generate grain structures,the phase field model for grain growth is also *** hysteresis loop and butterfly curve are predicted at room and high *** permittivity,and longitudinal and transverse piezoelectric constants of the BaTiO_(3) polycrystals are then examined for various grain sizes and oxygen vacancy densities.

关键词： Mesomechanics phase field method ferroelectric ceramics piezoelectric property smart materials and structures

The Aesthetics of Nature in Deleuze＇s Philosophy

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Journal of Philosophy Study 2013年第9期3卷 880-887页

作者： takuya kobayashi Ph.D. candidate Researcher Lecturer Faculty of Cultural Studies Kyoto Sangyo University Japan

In Critique of Pure Reason （1996）, Immanuel Kant says that the term ＂aesthetic＂ means ＂the science of the laws of sensibility＂ and suggests giving up usage of it to indicate ＂the critique of taste＂ which executes the criticism of the beautiful. It is well known that Gilles Deleuze was inspired by all genres of the arts, namely movies, paintings, music, and so on. However, this paper argues that what is more essential for Deleuzian philosophy is aesthetics as a science of sensibility. What motivated Deleuze, especially from the 1950s to the 1960s, seems to have consisted in discovering the weaknesses of the Kantian aesthetic in order to take it apart. In fact, one of the main themes in Difference and Repetition （1994） was to free ＂sensibility＂ itself from Kant＇s philosophical system. This theme subsisted in his writing even after the 1970s, and led him to develop a ＂natural philosophy＂ of sorts. This is because the supposition that ＂the sensibility itself＂ is independent from any human faculties gave him an opportunity to carefully consider the multiplicity and productivity of Nature itself. Finally, Deleuze created his own ＂ethology＂ that would capture the increasingly interrelated movements within Nature produced by heterogeneous elements. This paper describes the process of Deleuzian thought as outlined above, surveying his view of Kantian philosophy and the development of his natural philosophy as ＂the aesthetics of Nature.＂

关键词： Deleuze aesthetics natural philosophy Kant ethology

Heat Transfer and Flow Characteristics of Water Flow with Air Injection in Polyethylene Tube Placed over Metal Rods: Influence of Pitch Length and Tube Width

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Journal of Flow Control, Measurement & Visualization 2018年第1期6卷 1-14页

作者： takuya kobayashi Koji Toriyama Shumpei Funatani Department of Education Integrated Graduate School of Medicine Engineering and Agricultural Sciences University of Yamanashi Yamanashi Japan Department of Research Interdisciplinary Graduate School of Engineering University of Yamanashi Yamanashi Japan

A polyethylene tube can be used as a heat exchanger for a low-running-cost?temperature control system. In this system, the flow of temperature-controlled?water in the tube is used as the heat source, and the tube is placed on the ceiling of a temperature-controlled space using a metal net. Owing to this structure, the tube is deformed by its weight. This deformation has a significant influence on heat transfer and flow characteristics. Therefore, an air injection method, in which air and water are injected simultaneously into the tube, is developed for preventing the deformation of the tube. In this study, bedding metal rods were used instead of a metal net. The influence of the pitch length of the metal rods (5 - 15 cm) and the width of the polyethylene tube 15, 20, 25, 30, and 35 cm was examined experimentally. The length of the polyethylene tube was 178 cm. The air flow rate was 9.5 × 10-5 m3/s. The water flow rates were 60, 80, 100, 120, and 140 mL/min. Results show that the thermal response improved because of air injection. In particular, the temperature at steady state increased, and steady state was attained approximately 1.2 - 3 times faster with air injection than without air injection. The optimum pitch length of the metal rods and the range of the optimum width of the polyethylene tube were 8 cm and 20 - 25 cm, respectively, with and without air injection.

关键词： Polyethylene Tube Air Injection Heat Transfer Flow Characteristics Thermal Response

Rapid transformation of branched pancreatic duct-derived intraductal tubulopapillary neoplasm into an invasive carcinoma: A case report

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World Journal of Clinical Oncology 2023年第12期14卷 620-627页

作者： Kenta Yamamoto Yutaka Takada takuya kobayashi Ryo Ito Yuka Ikeda Shogo Ota Kanna Adachi YukariShimada Motohito Hayashi Toshinao Itani Satsuki Asai Kojiro Nakamura Department of Gastroenterology and Hepatology Kobe City Nishi-Kobe Medical CenterKobe 651-2273HyogoJapan Department of Pathology Kobe City Nishi-Kobe Medical CenterKobe 651-2273HyogoJapan Department of Surgery and Gastroenterological Surgery Kobe City Nishi-Kobe Medical CenterKobe 651-2273HyogoJapan

BACKGROUND Intraductal tubulopapillary neoplasm(ITPN)is a rare disease accounting for approximately 3%of all intraductal pancreatic tumors,with intraductal papillary mucinous neoplasm(IPMN)being one of the most common differential *** ITPN and IPMN display slow growth.A branched pancreatic duct type is commonly observed in IPMN,whereas ITPN derived from the branched pancreatic duct has been reported in a limited number of cases;hence,its pathogenesis remains *** SUMMARY Here,we present the case of a patient with ITPN localized in a branched pancreatic duct,with poorly controlled irritable bowel syndrome.A contrastenhanced computed tomography scan of the abdomen incidentally revealed a 5-mm oligemic nodule-like change in the body of the *** ultrasound(EUS)indicated a 10-mm hypoechoic mass without any cystic structures that had grown within 2 ***-guided fine needle aspiration was performed for definitive diagnosis,and the findings suggested ductal papillary *** pancreatectomy was performed,and the tumor was pathologically diagnosed as ITPN with an invasive cancerous component,pT3N1aM0,pStage IIB(International Cancer Control,8^(th) edition).The patient underwent treatment with postoperative adjuvant chemotherapy(S-1 monotherapy);however,relapse was observed 1 year and 10 mo after surgical resection,and subsequent treatment involving a combination of chemotherapy and radiotherapy was *** therapy has since facilitated a stable disease *** Regardless of the microscopic size of the neoplasm,early diagnosis of ITPN with EUS-guided fine needle aspiration and surgical resection are crucial.

关键词： Intraductal tubulopapillary neoplasm Pancreatic tumors Neoplasia Carcinoma Pancreaticoduodenectomy Case report

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利格列汀治疗可改善餐后高脂血症

利格列汀治疗可改善餐后高脂血症

Hybrid Rubisco with Complete Replacement of Rice Rubisco Small Subunits by Sorghum Counterparts Confers C4 Plant-like High Catalytic Activity

中华医学会第十二次全国内分泌学学术会议

作者： Daisaku Masuda takuya kobayashi Takeshi Okada Hajime Nakaoka Ryota Kawase Kazuhiro Nakatani Tohru Ohama Makoto Nishida Akifumi Matsuyama Issei Komuro Shizuya Yamashita Department of Cardiovascular Medicine Osaka University Graduate School of Medicine Health Care Center Osaka University

目的:探讨DPP-4抑制剂改善餐后高甘油三酯血症的机制。方法:雄性C57BL/6J小鼠(8周龄)标准饲料(NC)或含有利格列汀的标准饲料(NC+利格列汀,0.083g/kg饲料)喂饲4周(n=10/组)。在隔夜空腹后,经口喂饲负荷剂量

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Molecular Plant 2020年第11期13卷 1570-1581页

作者： Hiroyoshi Matsumura Keita Shiomi Akito Yamamoto Yuri Taketani Noriyuki kobayashi takuya Yoshizawa Shun-ichi Tanaka Hiroki Yoshikawa Masaki Endo Hiroshi Fukayama Department of Biotechnology College of Life SciencesRitsumeikan University1-1-1 Noji-HigashiKusatsu 525-8577Japan Graduate School of Agricultural Science Kobe University1-1 Rokkodai-tyouNada-kuKobe 657-8501Japan Faculty of Agriculture Kobe University1-1 Rokkodai-tyouNada-kuKobe 657-8501Japan Division of Applied Genetics Institute of Agrobiological SciencesNational Agriculture and Food Research Organization1-2 OwashiTsukuba 305-8634Japan Department of Biomolecular Chemistry Kyoto Prefectural UniversityHangi-choShimogamoSakyo-kuKyoto 606-8522Japan

Photosynthetic rate at the present atmospheric condition is limited by the CO2-fixing enzyme ribulose-1,5-bisphosphate carboxylase/oxygenase(Rubisco)because of its extremely low catalytic rate(kcat)and poor affinity for C02(Kc)and specificity for CO2(Sc/O).Rubisco in C4 plants generally shows higher k cat than that in C3 *** consists of eight large subunits and eight small subunits(RbcS).Previously,the chimeric incorporation of sorghum C4-type RbcS significantly increased the k cat of Rubisco in a C3 plant,*** this study,we knocked out rice RbcS multigene family using the CRISPR-Cas9 technology and completely replaced rice RbcS with sorghum RbcS in rice *** hybrid Rubisco showed almost C4 plant-like catalytic properties,i.e.,higher kcai,higher Kc,and lower Sc/*** lines expressing the hybrid Rubisco accumulated reduced levels of Rubisco,whereas they showed slightly but significantly higher photosynthetic capacity and similar biomass production under high C 02 condition compared with wild-type ***-resolution crystal structural analysis of the wild-type Rubisco and hybrid Rubisco revealed the structural differences around the central pore of Rubisco and the pC-pD hairpin in *** propose that such differences,particularly in the pC-pD hairpin,may impact the flexibility of Rubisco catalytic site and change its catalytic properties.

关键词： CRISPR-Cas9 C4 plant photosynthesis rice Rubisco

Thermochemical Heat Storage Performance in the Gas/Liquid-Solid Reactions of SrCl₂ with NH₃

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Natural Resources 2016年第11期7卷 655-665页

作者： Kazuki Kuwata Soichirou Masuda Noriyuki kobayashi takuya Fuse Toru Okamura Department of Chemical Engineering Nagoya University Nagoya Japan Denso Corporation Kariya Japan

Thermochemical heat storage is a promising technology for improving energy efficiency through the utilization of low-grade waste heat. The formation of a SrCl2 ammine complex was selected as the reaction system for the purpose of this study. Discharge characteristics were evaluated in a packed bed reactor for both the gas-solid reaction and the liquid-solid reaction. The average power of the gas-solid reaction was influenced by the pressure of the supplied ammonia gas, with greater powers being recorded at higher ammonia pressure. For the liquid-solid reaction, the obtained average power was comparable to that obtained for the gas-solid reaction at 0.2 MPa. Moreover, the lower heat transfer resistance in the reactor was observed, which was likely caused by the presence of liquid ammonia in the system. Finally, the short-term durability of the liquid-solid reaction system was demonstrated over 10 stable charge/discharge cycles.

关键词： Thermochemical Heat Storage SrCl2 Ammine Complex Formation Gas/Liquid-Solid Reaction

Effect of the Pixel Interpolation Method for Downsampling Medical Images on Deep Learning Accuracy

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Journal of Computer and Communications 2021年第11期9卷 150-156页

作者： Daisuke Hirahara Eichi Takaya Mizuki Kadowaki Yasuyuki kobayashi takuya Ueda Department of AI Research Lab Harada Academy Kagoshima Japan Department of Clinical Imaging Graduate School of Medicine Tohoku University Sendai Japan Department of Advanced Biomedical Imaging Informatics St. Marianna University School of Medicine Kawasaki Japan Tohoku University Hospital AI Lab Sendai Japan

Background: High-resolution medical images often need to be downsampled because of the memory limitations of the hardware used for machine learning. Although various image interpolation methods are applicable to downsampling, the effect of data preprocessing on the learning performance of convolutional neural networks (CNNs) has not been fully investigated. Methods: In this study, five different pixel interpolation algorithms (nearest neighbor, bilinear, Hamming window, bicubic, and Lanczos interpolation) were used for image downsampling to investigate their effects on the prediction accuracy of a CNN. Chest X-ray images from the NIH public dataset were examined by downsampling 10 patterns. Results: The accuracy improved with a decreasing image size, and the best accuracy was achieved at 64 × 64 pixels. Among the interpolation methods, bicubic interpolation obtained the highest accuracy, followed by the Hamming window.

关键词： Downsampling Interpolation Deep Learning Convolutional Neural Networks Medical Images Nearest Neighbor Bilinear Hamming Window Bicubic Lanczos

Anomeric Proton and Carbon (H1-C1) NMR Chemical Shifts of Antigenic Mannans Obtained from Pathogenic Yeast <i>Candida tropicalis</i>

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Advances in Microbiology 2021年第5期11卷 296-301页

作者： takuya Kuraoka Takayoshi Yamada Yuki Takatsutsumi Yukiko Ogawa Hidemitsu kobayashi Divisions of Microbiology Department of Pharmaceutical Science Nagasaki International University Nagasaki Japan Divisions of Infection Control and Prevention Department of Pharmaceutical Science Nagasaki International University Nagasaki Japan

On two dimensional maps of 1H-13C correlation spectroscopy (H-C COSY) analysis for the mannan of Candida tropicalis, nine cross peaks of anomeric proton and carbon were useful for the purpose of obtaining information on the chemical structure of this molecule. Namely, the mannans was comb-like structure constructed with the linear α-1,6-linked polymannnosyl backbone and several oligomannnosyl side chains composed of α-1,2-, α-1,3-, and β-1,2-linkages. Therefore, in the structural investigation of comb-like mannan, two-dimensional H-C COSY analysis is as useful as two-dimensional nuclear Hartmann-Hahn (HOHAHA) analysis.

关键词： Candida tropicalis Cell Wall Mannan Comb-Like Structure 1H-13C Correlation Spectroscopy Anomeric Carbon Chemical Shift α-1 3-Linked Mannose

Lithium isotopic systematics of peridotite xenoliths from Hannuoba,North China Craton:Implications for melt-rock interaction in the considerably thinned lithospheric mantle

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Lithium isotopic systematics of peridotite xenoliths from Ha...