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Protracted anaphylaxis developed after peginterferon α-2a administration for chronic hepatitis C

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World Journal of Gastroenterology 2015年第9期21卷 2826-2829页

作者： Akihiko Sakatani Yoshinori Doi takaaki matsuda Yasutaka Sasai Naohiro Nishida Megumi Sakamoto Naoto Uenoyama Yoshiya Matsumoto Kazuo Kinoshita Department of Gastroenterology and Hepatology Osaka University Graduate School of MedicineSuitaOsaka 565-0871Japan Department of Gastroenterology Otemae HospitalOsaka 540-0008Japan Department of Respiratory Medicine Otemae HospitalOsaka 540-0008Japan

Peginterferon is a key drug used to treat chronic viral hepatitis that is known for causing various side *** effects occurring immediately after administration include headache, nausea, and influenza-like symptoms, such as fever and joint ***, reports of anaphylactic shock are extremely *** we report a patient with protracted anaphylaxis who suffered shock symptoms after peginterferon α-2a administration for chronic hepatitis *** the patient improved temporarily with shock treatment, symptoms of anaphylaxis *** peginterferon is often administered on an outpatient basis, it is important to recognize life-threatening side effects that may develop in a protracted manner.

关键词： Peginterferon α-2a Anaphylaxis Anaphylactic shock

关于中新世日本海张开的简要评述——根据日本岛弧古地磁证据

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地球物理学进展 1987年第1期 58-62页

作者： Yo-Ichiro Otofuji takaaki matsuda Susumu Nohda 郝天珧

自1980年初以来,在日本岛弧地区加强了对晚第三纪火山岩与沉积岩的古地磁研究。我们在此对日本东北部及日本西南部的古地磁工作进行评述,这些工作推断出在21Ma到11Ma期间日本东北弧绕垂直轴逆时针旋转了47°,而日本西南弧顺时针旋转了5... 详细信息

自1980年初以来,在日本岛弧地区加强了对晚第三纪火山岩与沉积岩的古地磁研究。我们在此对日本东北部及日本西南部的古地磁工作进行评述,这些工作推断出在21Ma到11Ma期间日本东北弧绕垂直轴逆时针旋转了47°,而日本西南弧顺时针旋转了56°。两弧旋转过程给出日本海张开的时期和方式的合理估计。

关键词：古地磁研究日本东北日本日本海朝鲜东海西南部中新世第三纪

Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome-wide association and whole genome sequencing analyses

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Cancer Communications 2024年第2期44卷 287-293页

作者： Kouya Shiraishi Atsushi Takahashi Yukihide Momozawa Yataro Daigo Syuzo Kaneko Takahisa Kawaguchi Hideo Kunitoh Shingo Matsumoto Hidehito Horinouchi Akiteru Goto Takayuki Honda Kimihiro Shimizu Masahiro Torasawa Daisuke Takayanagi Motonobu Saito Akira Saito Yuichiro Ohe Shun-ichi Watanabe Koichi Goto Masahiro Tsuboi Katsuya Tsuchihara Sadaaki Takata Tomomi Aoi Atsushi Takano Masashi Kobayashi Yohei Miyagi Kazumi Tanaka Hiroyuki Suzuki Daichi Maeda Takumi Yamaura Maiko matsuda Yoko Shimada takaaki Mizuno Hiromi Sakamoto Teruhiko Yoshida Yasushi Goto Tatsuya Yoshida Taiki Yamaji Makoto Sonobe Shinichi Toyooka Kazue Yoneda Katsuhiro Masago Fumihiro Tanaka Megumi Hara Nobuo Fuse Satoshi S.Nishizuka Noriko Motoi Norie Sawada Yuichiro Nishida Kazuki Kumada Kenji Takeuchi Kozo Tanno Yasushi Yatabe Kuniko Sunami Tomoyuki Hishida Yasunari Miyazaki Hidemi Ito Mitsuhiro Amemiya Hirohiko Totsuka Haruhiko Nakayama Tomoyuki Yokose Kazuyoshi Ishigaki Toshiteru Nagashima Yoichi Ohtaki Kazuhiro Imai Ken Takasawa Yoshihiro Minamiya Kazuma Kobayashi Kenichi Okubo Kenji Wakai Atsushi Shimizu Masayuki Yamamoto Motoki Iwasaki Koichi matsuda Johji Inazawa Yuichi Shiraishi Hiroyoshi Nishikawa Yoshinori Murakami Michiaki Kubo Fumihiko matsuda Yoichiro Kamatani Ryuji Hamamoto Keitaro Matsuo Takashi Kohno Division of Genome Biology National Cancer Center Research InstituteTokyoJapan Department of Clinical Genomics National Cancer Center Research InstituteTokyoJapan Laboratory for Statistical Analysis Center for Integrative Medical SciencesRIKENYokohamaJapan Department of Genomic Medicine Research InstituteNational Cerebral and Cardiovascular CenterOsakaJapan Laboratory for Genotyping Development Center for Integrative Medical SciencesRIKENYokohamaJapan Center for Antibody and Vaccine Therapy Research HospitalInstitute of Medical ScienceThe University of TokyoTokyoJapan Department of Medical Oncology and Cancer Center and Center for Advanced Medicine against CancerShiga University of Medical ScienceOtsuJapan Division of Medical AI Research and Development National Cancer Center Research InstituteTokyoJapan Center for Genomic Medicine Graduate School of MedicineKyoto UniversityKyotoJapan Department of Medical Oncology Japanese Red Cross Medical CenterTokyoJapan Department of Thoracic Oncology National Cancer Center Hospital EastJapan Department of Thoracic Oncology National Cancer Center HospitalTokyoJapan Department of Cellular and Organ Pathology Graduate School of MedicineAkita UniversityAkitaJapan Department of Respiratory Medicine Tokyo Medical and Dental UniversityBunkyo-kuTokyoJapan Division of General Thoracic Surgery Department of SurgeryShinshu University School of MedicineMatsumotoNaganoJapan Department of General Surgical Science Division of General Thoracic SurgeryGunma University Graduate School of MedicineIntegrative Center of General SurgeryGunma University HospitalGunmaJapan Department of Gastrointestinal Tract Surgery Fukushima Medical University School of MedicineFukushimaJapan StaGen Co. LtdTokyoJapan Division of Thoracic Surgery National Cancer Center HospitalTokyoJapan Department of Thoracic Surgery National Cancer Center Hospital EastChibaJapan Division of Translational Informatics Exploratory Oncology Research and Clinical Trial Center(EPOC

Dear editor,Lung carcinoma is responsible for the highest fatal-ity rate among cancer-related deaths globally,with lung adenocarcinoma(LADC)emerging as the prevailing sub-type.

关键词： adenocarcinoma lung Lung

Direct visualization of postoperative aortobronchial fistula on computed tomography

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World Journal of Radiology 2024年第8期16卷 337-347页

作者： Nanae Tsuchiya Hitoshi Inafuku Satoko Yogi Yuko Iraha Gyo Iida Mizuki Ando takaaki Nagano Shotaro Higa Tatsuya Maeda Yuya Kise Kojiro Furukawa Koji Yonemoto Akihiro Nishie Department of Radiology Graduate School of Medical ScienceUniversity of the RyukyusOkinawa 903-0215Japan Department of Thoracic and Cardiovascular Surgery Graduate School of Medical ScienceUniversity of the RyukyusOkinawa 903-0215Japan Department of Biostatistics School of Health SciencesFaculty of MedicineUniversity of the RyukyusOkinawa 903-0215Japan

BACKGROUND Postoperative aortobronchial fistula(ABF)is a rare complication that can occur in 0.3%-5.0%of patients over an extended period of time after thoracic aortic *** visualization of the fistula via imaging is *** To investigate the relationship between computed tomography(CT)findings and the clinical signs/symptoms of ABF after thoracic aortic *** Six patients(mean age 71 years,including 4 men and 2 women)with suspected ABF on CT(air around the graft)at our hospital were included in this retrospective study between January 2004 and September *** CT findings included direct confirmation of ABF,peri-graft fluid,ring enhancement,dirty fat sign,atelectasis,pulmonary hemorrhage,and bronchodilation,and the clinical course were retrospectively *** proportion of each type of CT finding was *** ABF detection after surgery was found to have a mean and median of 14 and 13 years,*** signs and symptoms were asymptomatic in 4 patients,bloody sputum was found in 1 patient,and fever was present in 1 *** complications of ABF included graft infection in 2 patients and graft infection with hemoptysis in 2 *** the 6 patients,3 survived,2 died,and 1 was lost to *** locations of the ABFs were as follows:1 in the ascending aorta;1 in the aortic arch;2 in the aortic arch leading to the descending aorta;and 2 in the descending *** were directly confirmed by CT in 4/6(67%)***-graft dirty fat(4/6,67%)and peri-graft ring enhancement(3/6,50%)were associated with graft infection,endoleaks and pseudoaneurysms were associated with hemoptysis(2/6,33%).CONCLUSION Asymptomatic ABF after thoracic aortic surgery can be confirmed on chest *** is useful for the diagnosis of ABF and its complications.

关键词： Peri-graft air Aortobronchial fistula Chest computed tomography Postoperative Thoracic endovascular aortic repair Complication Thoracic aorta surgery

Material conversion from paper sludge ash in NaOH solution to synthesize adsorbent for removal of Pb^(2+),NH_4^+and PO_4^(3-) from aqueous solution

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Journal of Environmental Sciences 2011年第5期23卷 718-724页

作者： takaaki Wajima Kenzo Munakata Faculty of Engineering and Resource Sciences Akita University

Material conversion from paper sludge ash （PSA） in NaOH solution was attempted to synthesize the adsorbent for removal of inorganic pollutants, such as Pb^2＋, NH^4＋ and PO4^3- from aqueous solution. PSA of 0.5 g was added into 10 mL of 3 mol/L NaOH solution, and then heated at 80, 120, and 160℃ for 6-48 hr to obtain the product. PSA mainly composed of two crystalline phases, gehlenite （Ca2Al2SiO7） and anorthite （CaAl2Si2O8）, and amorphous phase. Hydroxysodalite （Na6Al6Si6O24-8H2O） was formed at 80℃, and anorthite dissolved, whereas gehlenite remained unaffected. Katoite （Ca3Al2SiO4（OH）8） was formed over 120℃, and hydroxycancrinite （Nas（OH）2Al6Si6O24·2H2O） was formed at 160℃, due to the dissolution of both gehlenite and anorthite. Specific surface areas of the products were almost same and were higher than that of raw ash. Cation exchange capacities （CECs） of the products were also higher than that of raw ash, and CEC obtained at lower temperature was higher. Removal abilities of products for Pb^2＋, NH4＋, and PO4^3- were higher than that of raw ash. With increasing reaction temperature, the removal efficiencies of Pb^2＋ and NH4＋ decreased due to the decrease of CEC of the product, while removal efficiency for PO4^3- was almost same. The concentrations of Si and AI in the solution and the crystalline phases in the solid during the reaction explain the formation of the product phases at each temperature.

关键词： paper sludge ash hydrothermal synthesis gehlenite anorhite heavy metal ion ammonium ion phosphate ion

Linear seesaw model with a modular S_(4)flavor symmetry

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Chinese Physics C 2022年第5期46卷 11-19页

作者： takaaki Nomura Hiroshi Okada College of Physics Sichuan UniversityChengdu 610065China Asia Pacific Center for Theoretical Physics(APCTP)-Headquarters San 31 Hyoja-dongNam-guPohang 790-784Korea Department of Physics Pohang University of Science and TechnologyPohang 37673Korea

We discuss a linear seesaw model with a field content as minimum as possible,introducing a modular S_(4)using gauged U(1)_(B−L) *** to the rank two neutrino mass matrix,we obtain a vanishing neutrino mass eigenvalue,and only the normal mass hierarchy of neutrinos is favored via the modular S_(4)*** our numericalΔχ^(2)analysis,we especially determine a relatively sharp prediction on the sum of neutrino masses to be approximately 60 meV,in addition to other predictions.

关键词： neutrino mass linear seesaw mechanism modular S_(4)flavor symmetry

Potentials of GHG reductions from wastewater treatment for the CDM

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Science China(Technological Sciences) 2011年第7期54卷 1649-1654页

作者： takaaki FURUBAYASHI Toshihiko NAKATA Department of Management Science & Technology Graduate school of Engineering Tohoku University

The study aims to evaluate the potential of GHG （greenhouse gas） reductions by installing an anaerobic digester in a wastewater treatment facility in Southeast Asia. Then the break-even point of additional investment to reduce GHG is obtained by exchanging carbon price as emissions credits. In the project scenario, the wastewater treatment system has the digester, where methane （biogas） is produced and recovered. Compared with the baseline scenario, the biogas has calorific value to produce heat and electricity, and can substitute fossil fuels for power generation. The objective of the study is to define the relationship between CERs （certified emission reductions） and investment costs, and the beak-even point, finding out the dominant pa- rameters in the system. Financial parameters such as capital costs and operating costs are considered to evaluate the investmerit costs. The result shows that the methane recovery reduces 54% of GHG emissions. Although the substitution of the biogas for the fossil fuels reduces only 6% of the GHG emissions, the electricity output can satisfy the electricity consumption. The results also show that the maximum CER credit is 73000 t-COEe/a, and the GHG reduction cost is 14 USD/t-CO2e.

关键词： wastewater treatment system anaerobic digestion GHG reductions developing countries CDM

Numerical Simulation for Fan Broadband Noise Prediction

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Journal of Thermal Science 2011年第1期20卷 58-63页

作者： takaaki Hase Nobuhiko Yamasaki Tsutomu Ooishi Kyushu University Fukuoka819-0395Japan IHI Corporation Nishitama-gunTokyo190-1297Japan

In order to elucidate the broadband noise of fan,the numerical simulation of fan operating at two different rotational speeds is carried out using the three-dimensional unsteady Reynolds-averaged Navier-Stokes (URANS) *** computed results are compared to experiment to estimate its accuracy and are found to show good agreement with experiment.A method is proposed to evaluate the turbulent kinetic energy in the framework of the Spalart-Allmaras one equation turbulence *** the calculation results,the turbulent kinetic energy is visualized as the turbulence of the flow which leads to generate the broadband noise,and its noise sources are identified.

关键词： Broadband Noise Fan Noise Rotor-Stator Interaction URANS

东日本大地震后某校舍抗震加固改造与效果评估实验研究

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噪声与振动控制 2024年第3期44卷 246-252页

作者：李亮大久保孝昭杨建江张大英天津仁爱学院建筑工程学院天津301636 日本国立广岛大学工学研究科日本广岛7308511 郑州航空工业管理学院土木建筑学院郑州450000

2011年东日本大地震后,校舍建筑的抗震加固变得极为迫切。针对日本某校舍建筑的抗震加固工程展开计算分析及实验研究。首先阐述既有校舍建筑的结构特征及抗震鉴定结果,提出纵向采用钢支撑框架提高强度,首层横向新设剪力墙以及增厚楼梯... 详细信息

2011年东日本大地震后,校舍建筑的抗震加固变得极为迫切。针对日本某校舍建筑的抗震加固工程展开计算分析及实验研究。首先阐述既有校舍建筑的结构特征及抗震鉴定结果,提出纵向采用钢支撑框架提高强度,首层横向新设剪力墙以及增厚楼梯间楼板的加固方案。随后,利用无线振动测试系统在校舍建筑抗震加固前后进行常时微动测试实验,分别从整体与局部角度分析加固前后校舍建筑加速度响应、固有周期以及振型等参数变化。最后,对比分析有限元计算及测试结果,阐述抗震加固方法及位置对原有建筑的性能影响,验证抗震加固方法的有效性。结果表明:采用钢支撑框架的加固方法有效提高既有校舍建筑的强度,加固后加速度响应值约降低至加固前的1/3,加固方法起到提高整体强度、改善刚度分布及结构整体性作用;固有周期以及加速度响应放大倍率的变化与该校舍抗震加固方法较吻合,表明基于振动测试的研究方法能够有效评估抗震加固措施的效果。研究成果可为既有校舍建筑的抗震加固方案选取及性能评估提供参考。

关键词：振动与波校舍建筑钢支撑框架抗震加固常时微动结构计算