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Improving Friend Recommendation for Online Learning with Fine-Grained Evolving Interest

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Journal of Computer Science & Technology 2022年第6期37卷 1444-1463页

作者： Ming-Min Shao Wen-Jun Jiang Jie Wu Yu-Qing shi tak.shing Yum Ji Zhang College of Computer Science and Electronic Engineering Hunan UniversityChangsha 410082China Department of Computer and Information Sciences Temple UniversityPhiladelphia 19122U.S.A. School of Computer Science and Engineering Northeastern UniversityShenyang 110819China Department of Information Engineering Chinese University of Hong KongHong Kong 999077China Department of Mathematics and Computing University of Southern QueenslandBrisbaneQLD 4350Australia

Friend recommendation plays a key role in promoting user experience in online social networks(OSNs).However,existing studies usually neglect users’fine-grained interest as well as the evolving feature of interest,which may cause unsuitable *** particular,some OSNs,such as the online learning community,even have little work on friend *** this end,we strive to improve friend recommendation with fine-grained evolving interest in this *** take the online learning community as an application scenario,which is a special type of OSNs for people to learn courses *** partners can help improve learners’learning effect and improve the attractiveness of *** propose a learning partner recommendation framework based on the evolution of fine-grained learning interest(LPRF-E for short).We extract a sequence of learning interest tags that changes over ***,we explore the time feature to predict evolving learning ***,we recommend learning partners by fine-grained interest *** also refine the learning partner recommendation framework with users’social influence(denoted as LPRF-F for differentiation).Extensive experiments on two real datasets crawled from Chinese University MOOC and Douban Book validate that the proposed LPRF-E and LPRF-F models achieve a high accuracy(i.e.,approximate 50%improvements on the precision and the recall)and can recommend learning partners with high quality(e.g.,more experienced and helpful).

关键词： online social network friend recommendation fine-grained interest evolving feature tag online learning community

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中国共产党坚持胸怀天下基本经验研究

太原理工大学学报（社会科学版） 2024年第4期42卷 30-37页

作者：石宇山西农业大学马克思主义学院山西晋中030801 南京大学马克思主义学院江苏南京210023

坚持胸怀天下是中国共产党百年奋斗积累的历史经验,也是中国共产党人不断推进实践基础上的理论创新所坚持的重要方法论原则。在新时代新征程中继续坚持和践行胸怀天下,需要在坚持顺应时代潮流与把握历史主动的辩证统一、营造自身良好发... 详细信息

坚持胸怀天下是中国共产党百年奋斗积累的历史经验,也是中国共产党人不断推进实践基础上的理论创新所坚持的重要方法论原则。在新时代新征程中继续坚持和践行胸怀天下,需要在坚持顺应时代潮流与把握历史主动的辩证统一、营造自身良好发展环境与维护世界和平的辩证统一、赢得自身发展与为世界做出更大贡献的辩证统一、关注人类前途命运与塑造自身良好形象的辩证统一中实现中国与世界的良性互动,实现“立己”与“达人”的相统一,为实现中华民族伟大复兴和世界和平与发展不懈奋斗。

关键词：中国共产党胸怀天下和平发展世界贡献

SAR-LAM:面向小样本SAR目标识别的轻量化适应策略

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空军工程大学学报 2024年第3期25卷 103-111页

作者：史松昊王晓丹空军工程大学防空反导学院西安710051

针对小样本学习中跨域迁移导致模型性能下降的问题,提出一种面向小样本SAR目标识别的轻量化适应策略(SAR-LAM)。该方法通过知识蒸馏预训练一个具有泛化性能的通用编码器,向其中嵌入一个只在少量目标域样本上进行训练的适应模块,而后将... 详细信息

针对小样本学习中跨域迁移导致模型性能下降的问题,提出一种面向小样本SAR目标识别的轻量化适应策略(SAR-LAM)。该方法通过知识蒸馏预训练一个具有泛化性能的通用编码器,向其中嵌入一个只在少量目标域样本上进行训练的适应模块,而后将提取的特征映射到一个分辨性更高的空间内,最终以原型网络为基线对查询集样本进行分类。该适应策略以增加少量学习参数为代价,克服了数据分布差异导致模型迁移受限的困难,增强了模型在目标域提取特征的能力,在小样本条件下将SAR目标识别的准确率提升了至少1.93个百分点,较其他方法展现出一定的优越性。

关键词： SAR目标识别跨域小样本学习轻量化

The Nano Research Young Innovators Awards in bio-inspired nanomaterials

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Nano Research 2024年第2期17卷 417-425页

作者： Jun Chen Shuotao Wang Department of Bioengineering University of CaliforniaLos AngelesLos AngelesCA 90095USA Key Laboratory of Bio-inspired Materials and Interfacial Science Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190China

Nano Research Young Innovators(NR45)Awards are designed to acknowledge and celebrate the achievements of young researchers under 45 years of *** individuals have made significant contributions to the field of nanoscience and *** the inaugural NR45 Awards in 2018,the journal's editorial board has recognized over a hundred innovators specializing in nanobiotechnology,nano energy,two-dimensional materials,and *** focus of the 2023 NR45 Awards is on bioinspired nanomaterials,acknowledging thirty-three outstanding young innovators for their extraordinary contributions in developing these materials with applications spanning clean energy,human healthcare,monitoring,and disease treatments,as shown in *** extend our heartfelt congratulations to all the 33 NR45 Awardees in 2023!

关键词： journal materials contributions

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1例肺隐球菌病患者抗感染治疗的药学分析

抗感染药学 2024年第5期21卷 451-456页

作者：杨少林熊世娟普定县中医医院药剂科贵州安顺562100 贵州省人民医院药剂科贵阳550002

目的:分析1例隐球菌感染患者的诊疗过程,为隐球菌病患者的救治提供参考。方法与结果:患者因“肺炎”被收入医院呼吸与危重症医学科治疗,在急诊时予祛痰、抗感染等治疗;入院第5天,根据患者血清隐球菌荚膜抗原检查、肺部CT影像学结果和炎... 详细信息

目的:分析1例隐球菌感染患者的诊疗过程,为隐球菌病患者的救治提供参考。方法与结果:患者因“肺炎”被收入医院呼吸与危重症医学科治疗,在急诊时予祛痰、抗感染等治疗;入院第5天,根据患者血清隐球菌荚膜抗原检查、肺部CT影像学结果和炎症指标结果,支持诊断为肺隐球菌病,予加用氟康唑氯化钠注射液抗感染治疗,临床药师通过对肺隐球菌病患者抗感染治疗的分析,结合患者临床症状、用药调整、病情转归情况与查阅相关文献,考虑患者身体质量指数为28为肥胖,为保证体内达到有效血药浓度,负荷氟康唑剂量可给到0.84 g,建议予患者经静脉滴注氟康唑氯化钠注射液(400 mg,q12h);入院第7天,患者临床症状较前改善,减少给药频率予氟康唑氯化钠注射液(0.4 g,q24h)抗感染治疗;入院第13天,患者肺部CT提示炎症较前进展,继续予抗感染;入院第17天,患者整体状况尚可,准予出院。结论:临床药师在参与隐球菌抗感染用药治疗过程中,通过积极开展药学监护和用药教育,结合患者实际情况,充分考虑其基础疾病(糖尿病)对感染和自身抵抗力影响和患者自身体质情况,兼顾药物不良反应与相互作用,制定个体化用药方案,获得了制定肺隐球菌病治疗方案的宝贵经验。

关键词：新型隐球菌肺隐球菌病氟康唑药学监护临床药师

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低变质煤CO来源及防控技术研究

煤矿安全 2024年第1期55卷 132-138页

作者：王永敬王坤陈洋师吉林秦乐静煤炭科学研究总院北京100013 中煤科工集团沈阳研究院有限公司辽宁抚顺113122 煤矿安全技术国家重点实验室辽宁抚顺113122 中国矿业大学(北京) 北京100083

为了研究低变质煤CO来源,降低煤层自然发火风险;以大南湖一矿3#煤层为研究对象,通过程序升温实验、实验模拟及现场观测等手段,研究3#煤层CO赋存、开采及割煤中CO产生规律及回风隅角CO来源占比等规律。结果表明:煤在无氧下粉碎,煤分子共... 详细信息

为了研究低变质煤CO来源,降低煤层自然发火风险;以大南湖一矿3#煤层为研究对象,通过程序升温实验、实验模拟及现场观测等手段,研究3#煤层CO赋存、开采及割煤中CO产生规律及回风隅角CO来源占比等规律。结果表明:煤在无氧下粉碎,煤分子共价键断裂生成的大量官能团、自由基相互作用产生极少量CO;煤在有氧下粉碎,产生大量CO,随煤样比表面积增大,CO体积分数随之增加并最终趋于稳定;采煤机割煤中产生高温使煤体发生氧化产生CO体积分数为(30~50)×10^(-6);回风隅角CO来源于采空区的CO体积分数占回风隅角CO总体积分数的28%,70%以上的CO来源于生产时期后溜破碎煤体氧化。根据低变质煤CO来源,采取了有针对性的架后喷洒CO复合抑制剂、采空区压注冷氮及漏风封堵等综合防控措施,使回风隅角及回风流CO体积分数大幅降低。

关键词：低变质煤自然发火程序升温 CO赋存复合抑制剂

Structural, densitometric and biomechanical evaluations of Chinese patients with long-term bisphosphonate treatment

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Chinese Medical Journal 2013年第1期126卷 27-33页

作者： LEUNG Kwok-sui TANG Ning James Griffith CHOY tak-Kee HUNG Vivian Wing-Yin MOK Hoi-Wa shi Lin LEUNG Ping-Chung CHEUNG Wing-Hoi Department of Orthopaedics and Traumatology and Bone Quality and Health Center The Chinese University of Hong Kong Shatin Hong Kong SAR China Department of Imaging and Interventional Radiology The Chinese University of Hong Kong Shatin Hong Kong SAR China The Jockey Club Center for Osteoporosis Care and Control The Chinese University of Hong Kong Shatin Hong Kong SAR China Orthopaedic Research Laboratory of Translational MedicineResearch and Development Center Institute of Biomedical andHealth Engineering Shenzhen Institutes of Advanced TechnologyChinese Academy of Sciences China

Background The association of long-term bisphosphonate treatment for osteoporosis and related safety problems such as atypical fractures were not clearly defined. This study was to evaluate the structural, densitometric and biomechanical properties of the prolonged bisphosphonate-loaded bones. Methods Bone mineral density （BMD） at hip and femoral midshaft, bone cross-sectional area, moment of inertia of both femurs, bone formation and resorption biochemical markers were compared between 28 elderly with at least 4 years of bisphosphonate treatment from 2002 through 2006 and age-matched group of 37 elderly. Results The total hip BMD and t-score were found not different between two groups. However, bisphosphonate treated patients were found to have significantly lower bone mineral content in the femoral shaft （P 〈0.05）; morphological study showed lower cross-sectional area in subtrochanteric and mid-diaphyseal region and thus significantly lower moment of inertia （P 〈0.01）. High resolution-peripheral quantitative computed tomography showed significantly decreased trabeculardensity, bone volume ratio, trabecular number but increased trabecular spacing in tibia and distal radius. Finite element analysis further confirmed significantly lower stiffness and failure load in tibia. Biochemical studies also showed lower bone resorption and severely suppressed bone formation activity （P 〈0.001）. Conclusions The unchanged total hip BMD between two groups confirmed the beneficial effects of bisphosphonate on trabecular bone, thus preventing osteoporotic fractures at large in previous studies. However, the inferior structural, densitometric and biomechanical properties at cortical bones, especially femur midshaft, need a special attention to look into the association between long-term bisphosphonate intake and the occurrence of stress fractures. When patients taking bisphosphonate complain of proximal thigh pain or discomfort, plain X-ray film can be the first line screening. All

关键词： bisphosphonate bone mineral density moment of inertia HR-pQCT cortical bone

Caenorhabditis elegans mom-4 is required for the activation of the p38 MAPK signaling pathway in the response to Pseudomonas aeruginosa infection

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Protein & Cell 2013年第1期4卷 53-61页

作者： Ajing Xu Guojun shi Feng Liu Baoxue Ge Department of Pharmacology Xinhua HospitalSchool of MedicineShanghai 200092China Shanghai pulmonary hospital Tongji University School of MedicineShanghai 200092China Lab of Signal Transduction Institute of Health SciencesShanghai Institutes for Biological SciencesChinese Academy of Sciences and Shanghai Jiao-Tong University School of MedicineShanghai 200025China Graduate School of the Chinese Academy of Sciences Beijing 100049China

The p38 mitogen-activated protein kinase(MAPK)plays an evolutionarily conserved role in the cellular re-sponse to microbial infection and environmental *** of p38 is mediated through phosphorylation by upstream MAPKK,which in turn is activated by *** the Caenorhabditis elegans,the p38 MAPK(also called PMK-1)signaling pathway has been shown to be required in its resistance to bacterial ***,how different upstream MAP2Ks and MAP3Ks specifically contribute to the activation of PMK-1 in response to bacterial infection still is not clearly *** using double-stranded RNA-mediated interference(RNAi)and genetic mutants of ***,we demonstrate that *** MOM-4,a mammalian tak1 homolog,is required for the resistance of *** to a *** *** have also found that the MKK-4 of *** is required for *** resistance,but not through the regulation of *** summary,our results indicate that different upstream MAPKKKs or MAPKKs regulate the activation of PMK-1 in response to ***.

关键词： C.elegans MAPK innate immunity p38 P.aeruginosa PA-14 MOM-4

Coronary bifurcation angle from 3-D predicts clinical outcomes after stenting bifurcation lesions

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Chinese Medical Journal 2012年第12期125卷 2083-2088页

作者： CHEN Shao-liang Teguh Santoso ZHANG Jun-jie YE Fei XU Ya-wei FU Qiang KAN Jing Chitprapai Paiboon ZHOU Yong DING shi-qing tak W Kwan Department of Cardiology Nanjing First Hospital NanjingMedical University Nanjing Jiangsu 210006 China Department of Cardiology Medistra Hospital University ofIndonesia Medical School Jakarta Indonesia Department of Cardiology Shanghai 10th People＇s HospitalShanghai 200072 China Department of Cardiology Xuzhou Central Hospital XuzhouJiangsu 221009 China Department of Cardiology Bangkok General Hospital BangkokThailand Department of Cardiology Zhangjiagang People＇s HospitalZhangjiagang Jiangsu 215600 China Department of Cardiology Huainan Xinhua Hospital HuainanAnhui 232038 China Department of Cardiology Beth Israel Hospital NewYork USA

Background The predictive value of bifurcation angle （BA） for worse events after stenting bifurcation lesions remains to be unknown. The present study was to investigate the dynamic change of BA and clinical relevance for patients with coronary bifurcation lesions treated by drug-eluting stent （DES）. Methods BA was calculated by 3-D quantitative coronary analysis from 347 patients in DKCRUSH-II study. Primary endpoint was the occurrence of composite major adverse cardiac events （MACE） at 12-month, including cardiac death, myocardial infarction （MI） and target vessel revascularization （TVR）. Secondary end points were the rate of binary restenosis and stent thrombosis at 12-month. Results Stenting was associated with the reduction of distal BA. The cut-off value of distal BA for predicting MACE was 60°. Distal BA in 〈60° group had less reduction after stenting （（-1.96＋13.58）°vs. （-12.12±23.58）°, P 〈0.001）; two-stent technique was associated with significant reduction of distal BA （△（-4.05±14.20）°）, compared to single stent group （4＋1.55±11.73, P=0.003）; the target lesion revascularization （TLR）, TVR and MACE rate was higher in one-stent group （16.5%, 19.0% and 21.5%）, compared to two-stent group （3.8%, P=0.002; 7.5%, P=0.016; and 9.8%, P=0.024）, respectively. Among patients in ≥60° group, there were no significant differences in distal BA, stent thrombosis （ST）, MI, MACE, death, TLR, TVR between one- and two-stent groups; after stenting procedure, there was only slight change of distal BA in left anterior descending （LAD）-Ieft circumflex （LCX） subgroup （from （88.54±21.33）° at baseline to （82.44±31.72）° post-stenting）, compared to either LAD-diagonal branch （Di）, or LCX-obtuse marginal branch （OM）, or IRCA distal （RCAd）（all P 〈0.001 ）. Conclusion Two-stent technique was associated with significant reduction of distal BA. DK crush stenting had reduced rate of MACE in patients in 〈60° group, compared to one-stent technique.

关键词： coronary bifurcation lesions bifurcation angle major adverse cardiac events ROC curve