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Biomarker bust:meta-analyses reveal unreliability of neuronal extracellular vesicles for diagnosing parkinsonian disorders

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Neural Regeneration Research 2025年第1期20卷 201-202页

作者： Hash Brown taha Leonard Davis School of Gerontology University of Southern CaliforniaLos AngelesCAUSA

A range of neurodegenerative disorders,collectively termed parkinsonian disorders,present with a complex array of both motor and non-motor *** in this group are Parkinson’s disease(PD),dementia with Lewy bodies(DLB),multiple system atrophy(MSA),corticobasal syndrome(CBS),and progressive supranuclear palsy(PSP).These disorders are differentiated neuropathologically by their dominant protein pathologies involvingα-synuclein(α-syn)and/or tau,the types of brain cells affected,such as neurons,oligodendroglia,and astrocytes,and the specific brain regions involved(Tolosa et al.,2021).

关键词： disorders parkin

Immunoassay development guidelines for neurodegenerative disorders:lessons from a failed pS129-α-synuclein electrochemiluminescence immunoassay

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Neural Regeneration Research 2025年第10期20卷 2906-2908页

作者： Hash Brown taha Alanna Morris Leonard Davis School of Gerontology University of Southern CaliforniaLos AngelesCAUSA Deparmtent of Neurobiology David Geffen School of MedicineUniversity of California Los AngelesLos AngelesCAUSA

An aging population is a double-edged *** one hand,advancements in biotechnology and healthcare allow more people to enjoy longer *** the other hand,increases in the aging population accompany a surge in age-associated diseases,particularly neurodegenerative *** aging is the primary risk factor for many neurodegenerative disorders,living longer does not necessarily equate to maintaining a reasonable quality of life(Feigin et al.,2020).

关键词： aging degenerative necessarily

Using 3-D magnetic modeling to evaluate subsurface structures of the Siwa Oasis,Western Desert,Egypt

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Science China Earth Sciences 2012年第2期55卷 279-289页

作者： taha RABEH National Research Institute of Astronomy and Geophysics CairoEgypt IDL Faculty of ScienceLisbon UniversityPortugal

This work was designed to study the subsurface structures in the Siwa Oasis area of the Western Desert in Egypt and to determine their effects on surface geologic structures. A detailed land magnetic survey was performed in traverses covering about 400 km2 of the study area. The measured total magnetic field was corrected and reduced to the north magnetic pole. The reduction-to-pole aeromagnetic and Bouguer anomaly maps were used to obtain regional extensions of these subsurface structures, study the continuation of these structures in sedimentary rocks, and delineate the depths to the basement rocks. Data analysis was performed using trend analysis, Euler deconvolution, Werner deconvolution, the Hilbert transform of the analytical signal, and 3-dimensional magnetic modeling methods. The results indicate that the area is affected by tectonic forces in the E-W, N45°-65°E, and N35°-45°W trends, which are correlated with the directions of surface geologic lineaments. The depth to the basement rocks increases from 3.2 km in the southern part to about 3.6 km in the northern part of the area. The results are in good agreement with depths obtained from drill hole data in the area.

关键词： land magnetic survey aeromagnetic data gravity data fault and dyke parameters

Identification and control of a small-scale helicopter

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2010年第12期11卷 978-985页

作者： Abdelhakim DEBOUCHA Zahari taha Centre for Product Design and Manufacturing University of Malaya Faculty of Manufacturing Engineering and Management Technology University Malaysia Pahang

Designing reliable flight control for an autonomous helicopter requires a high performance dynamics *** this paper,a nonlinear autoregressive with exogenous inputs (NLARX) model is selected as the mathematical structure for identifying and controlling the flight of a small-scale helicopter.A neural network learning algorithm is combined with the NLARX model to identify the dynamic component of the rotorcraft unmanned aerial vehicle (RUAV).This identification process is based on the well-known gradient descent learning *** a case study,the multiple-input multiple-output (MIMO) model predictive control (MPC) is applied to control the pitch motion of the *** of the neural network output model are closely match with the real flight *** MPC also shows good performance under various conditions.

关键词： Dynamics model System identification Black box Small-scale helicopter Neural networks (NNs) Control design

Variational approach for the flow of Ree–Eyring and Casson fluids in pipes

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International Journal of Modeling, Simulation, and Scientific Computing 2016年第2期7卷 126-138页

作者： taha Sochi University College London Department of Physics&Astronomy Gower Street LondonWC1E 6BTUK

The flow of Ree–Eyring and Casson non-Newtonian fluids is investigated using a variational principle to optimize the total *** variationally obtained solutions are compared to the analytical solutions derived from the Weissenberg–Rabinowitsch–Mooney equation and the results are found to be identical within acceptable numerical errors and modeling approximations.

关键词： Fluid mechanics tube flow Ree-Eyring Casson Weissenberg-Rabinowitsch-Mooney variational method total stress optimization.

Anchor Selection for Topology Inference and Routing in Wireless Sensor Networks

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Journal of Communications and Information Networks 2020年第3期5卷 318-323页

作者： taha Bouchoucha Zhi Ding University of California DavisCalifornia 95616USA

Anchor-based ad-hoc networks utilize hop measurements to generate a virtual coordinate system for topology inference and routing applications.A common problem with such coordinate system is its sensitivity to anchor *** present a general formulation to the anchor node selection ***,we relax the optimization problem by deriving an upper-bound of the objective *** finally propose an iterative algorithm that consists in choosing additional anchor nodes based on the connectivity information provided by the current anchor *** simulations indicate that our anchor selection method is robust to missing measurements and improves network topology inference and routing performance.

关键词： anchor selection connectivity hop distance routing

Emissivity: A Program for Atomic Transition Calculations

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Communications in Computational Physics 2010年第5期7卷 1118-1130页

作者： taha Sochi University College London Department of Physics&AstronomyGower StreetLondonWC1E 6BTUK

In this article we report the release of a new program for calculating emissivity and other physical parameters in atomic transition *** program,which can be downloaded with its documentation and a sample of input and output files from ***/***,passed various rigorous tests and was used alongside R-matrix and Autostructure codes to generate theoretical data and analyze observational *** is particularly useful for investigating atomic transition lines in astronomical context as the program is capable of generating a huge amount of theoretical data and comparing it to observational line list.A number of atomic transition algorithms and analytical techniques are implemented within the program and can be very useful in various *** program can be described as fast and ***,it requires modest computational resources.

关键词： Atomic transition recombination autoionization emissivity computer code thermodynamic equilibrium decay routes Saha population

A new effective potential for deuteron

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Communications in Theoretical Physics 2022年第7期74卷 105-113页

作者： taha Koohrokhi Sehban Kartal Department of Physics Faculty of SciencesGolestan UniversityGorganIran Istanbul University Department of Physics34000IstanbulTurkey

We calculate for the first time the static properties of the deuteron, within the framework of supersymmetric quantum mechanics, analytically. A new effective potential and its partner are derived from a superpotential so that all parameters are fitted by the experimental data. An analytical expression is obtained for the deuteron wave function and contributions of the orthogonal ^(13)S_(1) and ^(13)D_(1) states are determined, explicitly. Compared to one pion exchange, the superpotential produces an electrostatic as well as two pion exchange terms for the potential. The saddle point radius of the potential and the maximum of the wave function are linearly proportional. In comparison with other methods, the approach presented in this paper is a new and extensible symmetry-based approach that, despite its straightforward calculations and explicit analytical expressions, provides a good explanation for two-body effective interactions such as two-nucleon systems and diatomic molecules.

关键词： superpotential Boson exchange supersymmetry effective potential

NEWTONIAN FLOW IN CONVERGING-DIVERGING CAPILLARIES

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International Journal of Modeling, Simulation, and Scientific Computing 2013年第3期4卷 84-96页

作者： taha SOCHI Imaging Sciences&Biomedical Engineering King’s College London The Rayne Institute St Thomas’HospitalLondonSE17EHUK

The one-dimensional Navier–Stokes equations are used to derive analytical expressions for the relation between pressure and volumetric flow rate in capillaries of five different converging-diverging axisymmetric geometries for Newtonian *** results are compared to previously derived expressions for the same geometries using the lubrication *** results of the one-dimensional Navier–Stokes are identical to those obtained from the lubrication approximation within a nondimensional numerical *** derived flow expressions have also been validated by comparison to numerical solutions obtained from discretization with numerical ***,they have been certified by testing the convergence of solutions as the converging-diverging geometries approach the limiting straight geometry.

关键词： Fluid dynamics one-dimensional Navier-Stokes converging-diverging capillaries Newtonian fluids.