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Spatial and spectral measurement of laser-driven protons through radioactivation

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Nuclear Science and Techniques 2023年第12期34卷 30-39页

作者： Yin‑Ren Shou Xue‑Zhi Wu Gwang‑Eun Ahn Seung Yeon Kim Seong hoon Kim Hwang Woon Lee Jin Woo yoon Jae Hee Sung Seong Ku Lee Xue‑Qing Yan Il Woo Choi Chang Hee Nam Center for Relativistic Laser Science Institute for Basic ScienceGwangju 61005Republic of Korea School of Physics Peking UniversityBeijing 100871China Advanced Photonics Research Institute Gwangju Institute of Science and TechnologyGwangju 61005Republic of Korea Department of Physics and Photon Science Gwangju Institute of Science and TechnologyGwangju 61005Republic of Korea

The simultaneous measurement of the spatial profile and spectrum of laser-accelerated protons is important for further optimization of the beam qualities and *** report a detailed study regarding the underlying physics and regular procedure of such a measurement through the radioactivation of a stack composed of aluminum,copper,and CR-39 plates as well as radiochromic films(RCFs).After being radioactivated,the copper plates are placed on imaging plates(IPs)to detect the positrons emitted by the reaction products through contact *** spectrum and energy-dependent spatial profile of the protons are then obtained from the IPs and confirmed by the measured ones from the RCFs and CR-39 *** also discuss the detection range,influence of electrons,radiation safety,and spatial resolution of this ***,insights regarding the extension of the current method to online measurements and dynamic proton imaging are also provided.

关键词： Laser-driven proton acceleration Proton-induced nuclear reaction Radioactivation measurement Contact imaging

Detection of Graphene Cracks By Electromagnetic Induction,Insensitive to Doping Level

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Computer Modeling in Engineering & Sciences 2019年第8期120卷 351-361页

作者： taeshik yoon Sumin Kang tae Yeob Kang taek-Soo Kim Department of Mechanical Engineering KAISTDaejeon 34141Korea Graphene Research Center KAISTDaejeon 34141Korea

Detection of cracks is a great concern in production and operation processes of graphene based devices to ensure uniform ***,we show a detection method for graphene cracks by electromagnetic *** time varying magnetic field leads to induced voltage signals on graphene,and the signals are detected by a *** measured level of induced voltage is correlated with the number of cracks in graphene *** correlation is attributed to the increasing inductive characteristic of defective graphene,and it is verified by electromagnetic simulation and radio frequency ***,we demonstrate that the induced voltage signal is insensitive to the doping level of *** work can potentially lead to the development of a high-throughput and reliable crack inspection technique for mass production of graphene applications.

关键词： Graphene,crack detection inductance electromagnetic induction insensitive to doping

Use of rotational atherectomy for reducing significant dissection in treating de novo femoropopliteal steno-occlusive disease after balloon angioplasty

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Journal of Geriatric Cardiology 2018年第4期15卷 254-260页

作者： tae-hoon Kim Manny Katsetos Khagendra Dahal Michael Azrin Juyong Lee University of Connecticut Health Center Connecticut USA Sejong General Hospital Bucheon South Korea Louisiana State University Health Science Center Shreveport LA USA

动脉的解剖的 BackgroundDevelopment 被认为是为在 femoropopliteal 疾病的跳伞 stenting 的一个重要关键因素。我们试图与旋转 atherectomy 并且没有 *** 2011年1月处于在处理组之间的解剖率和结果评估差别到2016年10月，我们在 de-no... 详细信息

动脉的解剖的 BackgroundDevelopment 被认为是为在 femoropopliteal 疾病的跳伞 stenting 的一个重要关键因素。我们试图与旋转 atherectomy 并且没有 *** 2011年1月处于在处理组之间的解剖率和结果评估差别到2016年10月，我们在 de-novo 的汽球 angioplasty ( BA )以后比较了 angiography ， femoropopliteal ，速闭塞的损害他们是否被旋转 atherectomy 在 BA 以前对待。59 损害(8 吸藏；3 包含的腿弯部的片断；损害长度：86.3

关键词：解剖旋转疾病闭塞风险因素损害 BA 最小化

Utility of a deep learning model and a clinical model for predicting bleeding after endoscopic submucosal dissection in patients with early gastric cancer

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World Journal of Gastroenterology 2022年第24期28卷 2721-2732页

作者： Ji Eun Na Yeong Chan Lee tae Jun Kim Hyuk Lee Hong-Hee Won Yang Won Min Byung-hoon Min Jun Haeng Lee Poong-Lyul Rhee Jae J Kim Department of Internal Medicine Inje University Haeundae Paik HospitalBusan 48108South Korea Department of Medicine Samsung Medical CenterSungkyunkwan University School of MedicineSeoul 06351South Korea Department of Digital Health Samsung Advanced Institute for Health Science and TechnologySungkyunkwan UniversitySeoul 06351South Korea

BACKGROUND Bleeding is one of the major complications after endoscopic submucosal dissection(ESD)in early gastric cancer(EGC)*** are limited studies on estimating the bleeding risk after ESD using an artificial intelligence *** To derivate and verify the performance of the deep learning model and the clinical model for predicting bleeding risk after ESD in EGC *** Patients with EGC who underwent ESD between January 2010 and June 2020 at the Samsung Medical Center were enrolled,and post-ESD bleeding(PEB)was investigated *** split the entire cohort into a development set(80%)and a validation set(20%).The deep learning and clinical model were built on the development set and tested in the validation *** performance of the deep learning model and the clinical model were compared using the area under the curve and the stratification of bleeding risk after *** A total of 5629 patients were included,and PEB occurred in 325 *** area under the curve for predicting PEB was 0.71(95%confidence interval:0.63-0.78)in the deep learning model and 0.70(95%confidence interval:0.62-0.77)in the clinical model,without significant difference(P=0.730).The patients expected to the low-(<5%),intermediate-(≥5%,<9%),and high-risk(≥9%)categories were observed with actual bleeding rate of 2.2%,3.9%,and 11.6%,respectively,in the deep learning model;4.0%,8.8%,and 18.2%,respectively,in the clinical *** A deep learning model can predict and stratify the bleeding risk after ESD in patients with EGC.

关键词： Clinical model Deep learning model Post-endoscopic submucosal dissection bleeding Stratification of bleeding risk

Injection molding of micro patterned PMMA plate

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Transactions of Nonferrous Metals Society of China 2011年第A1期21卷 148-152页

作者： Yeong-Eun YOO tae-hoon KIM tae-Jin JE Doo-Sun CHOI Chang-Wan KIM Sun-Kyung KIM Department of Nanomanufacturing Technology KIMM 171 Jang-dong Yusung-gu Daejeon 305-343 Korea Department of Product Design and Manufacturing Seoul National University of Technology

A plastic plate with surface micro features was injection molded to investigate the effect of pressure rise of melt on the replication of the micro structures. Prism pattern, which is used in many optical applications, was selected as a model pattern. The prism pattern is 50 μm in pitch and 108° in the vertical angle. The overall size of the plate was 335 mm×213 mm and the thickness of the plate varied linearly from 2.6 mm to 0.7 mm. The prism pattern was firstly machined on the nickel plated core block using micro diamond tool and this machined pattern core was installed in a mold for injection molding of prism patterned plate. Polymethyl methacrylate (PMMA) was used as a molding material. The pressure and temperature of the melt in the cavity were measured at different positions in the cavity and the replication of the pattern was also measured at the same positions. The results show that the pressure or temperature profile through the process depends on the shape and the size of the plate. The replication is affected by the temperature and pressure profiles at the early stage of filling, which is right after the melt reaches the position to be measured.

关键词： PMMA 注塑成型塑料板图案聚甲基丙烯酸甲酯压力上升加工模式位置测量

Clinical outcomes of endoscopic papillectomy of ampullary adenoma: A multi-center study

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World Journal of Gastroenterology 2022年第17期28卷 1845-1859页

作者： Seong Ji Choi Hong Sik Lee Jiyeong Kim Jung Wan Choe Jae Min Lee Jong Jin Hyun Jai hoon yoon Hyo Jung Kim Jae Seon Kim Ho Soon Choi Department of Internal Medicine Hanyang University College of MedicineSeoul 04763South Korea Division of Gastroenterology and Hepatology Department of Internal MedicineKorea University College of MedicineSeoul 02841South Korea Lab of Biostatistical Consulting and Research Medical Research Collaborating CenterIndustry-University Cooperation FoundationHanyang UniversitySeoul 04763South Korea

BACKGROUND Ampullary adenoma is a rare premalignant lesion,but its incidence is *** papillectomy has become the first treatment of choice for ampullary adenomas due to its safety and effectiveness,thereby replacing surgical ***,recurrence rates and adverse events after endoscopic papillectomy were reported in up to 30%of *** To review the long-term outcomes of endoscopic papillectomy and investigate the factors that affect these *** We retrospectively analyzed the data of patients who underwent endoscopic papillectomy for ampullary adenoma at five tertiary hospitals between 2013 and *** evaluated clinical outcomes and their risk *** definitions of outcomes were as follow:(1)curative resection:complete endoscopic resection without recurrence;(2)endoscopic success:treatment of ampullary adenoma with endoscopy without surgical intervention;(3)early recurrence:reconfirmed adenoma at the first endoscopic surveillance;and(4)late recurrence:reconfirmed adenoma after the first endoscopic *** A total of 106 patients were included for *** the included patients,81(76.4%)underwent curative resection,99(93.4%)had endoscopic success,showing that most patients with noncurative resection were successfully managed with *** patients(15.1%)had piecemeal resection,22 patients(20.8%)had shown positive/uncertain resection margin,11 patients(16.1%)had an early recurrence,13 patients(10.4%)had a late recurrence,and 6 patients(5.7%)had a *** multivariate analysis,a positive/uncertain margin[Odds ratio(OR)=4.023,P=0.048]and piecemeal resection(OR=6.610,P=0.005)were significant risk factors for early and late recurrence,*** resection was also a significant risk factor for non-curative resection(OR=5.424,P=0.007).Twenty-six patients experienced adverse events(24.5%).CONCLUSION Endoscopic papillectomy is a safe and effective treatment for ampullary ***

关键词： Endoscopic papillectomy Ampullary adenoma Clinical outcome Recurrence Adverse event

Effect of robot-assisted gait training on the biomechanical properties of burn scars:a single-blind,randomized controlled trial

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Burns & Trauma 2022年第1期10卷 191-199页

作者： yoon Soo Cho So Young Joo Cheong hoon Seo Department of Rehabilitation Medicine Hangang Sacred Heart HospitalCollege of MedicineHallym UniversitySeoul 07247Republic of Korea

Background:Robot-assisted gait training(RAGT)is more effective in the range of motion(ROM)and isometric strength in patients with burns than conventional ***,concerns have been raised about whether RAGT might negatively affect the scars of patients with ***,we investigated the effects of RAGT-induced mechanical load on the biomechanical properties of burn ***:This was a single-blind,randomized clinical trial conducted on inpatients admitted to the Department of Rehabilitation Medicine between September 2020 and August *** was conducted for 30 min per day,five days a week for 12 weeks and the control group received conventional gait training for 12 *** pre-training ROM of lower extremity joints was evaluated and the levels of melanin,erythema,trans-epidermal water loss,scar distensibility and elasticity were assessed before training and at 4 and 12 weeks after ***,19 patients in the gait assistance robot(GAR)group and 20 patients in the control group completed the 12-week trial and all ***:There were no significant differences in the epidemiologic characteristics,pre-training ROM of joints and pre-training biomechanical properties of the burn scar between the groups(p>0.05 for all).None of the patients experienced skin abrasion around the burn scar where the fastening belts were applied or musculoskeletal or cardiovascular adverse events during the *** thickness significantly increased in both groups(p=0.037 and p=0.019)and scar distensibility significantly decreased in the control group(p=0.011)during the *** was significantly decreased in the GAR group during the training(p=0.038).The GAR and control groups showed significant difference in the change in the values of hysteresis between pre-training and 12 weeks after training(p=0.441 and p=0.049).Conclusions:RAGT significantly decreased hysteresis in hypertrophic burn scars and did not cause a significant decrease

关键词： Robot-assisted gait training Burn Scar biomechanical properties Hysteresis Burn rehabilitation

Clinical Efficacy and Safety of Miniscalpel-Needle Treatment for Tension-Type Headache:A Systematic Review and Meta-Analysis

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Chinese Journal of Integrative Medicine 2020年第9期26卷 713-720页

作者： Chan-Young Kwon Sang-hoon yoon Sun-Yong Chung Jong Woo Kim Department of Clinical Korean Medicine Graduate SchoolKyung Hee U niversitySeoul(02447)Republic of Korea Chung-Yeon Central Institute Gwang-juRepublic of Korea Department of Oriental Neuropsychiatry Kyung Hee University Hospital at GangdongSeoul(02447)Republic of Korea

Objective:To investigate the clinical efficacy and safety of miniscalpel-needle(MSN)treatment for tension-type headache(TTH).Method:Seven medical databases were searched to identify randomized controlled trials(RCTs)evaluating the effect and safety of MSN *** articles published up to November 15,2018 were retrieved.A meta-analysis was conducted for the included studies,and the risk of bias was *** outcomes were visual analogue scale(VAS)or numeric rating scale(NRS)*** outcomes were clinical effective rates including total effective rate(TER),markedly effective rate(MER),and totally cured rate(TCR)determined by improvement in clinical symptoms or VAS scores,the frequency of adverse events(AEs)that occurred during the study,and participant quality of life(QOL).Results:Seven RCTs involving 724 participants were *** treatment showed significantly higher MER and TCR[relative risk(RR)1.27,95%confidence interval(Cl)1.01 to 1.61;RR 1.31,95%Cl 1.09 to 1.57,respectively],but not TER(RR 1.03,95%Cl 0.96 to 1.10)compared to *** treatment plus conventional treatment showed significant lower VAS and higher TER,MER,and TCR(mean difference-3.54,95%Cl-3.80 to-3.28;RR 1.14,95%Cl 1.06 to 1.23;RR 2.31,95%Cl 1.50 to 3.58;RR 3.01,95%Cl 2.25 to 4.02,respectively)compared to conventional ***:According to current evidence,MSN treatment as a monotherapy or as an adjunctive treatment to other existing treatments might have benefits on treating ***,since the number and the sample size of studies included were both small and the methodological quality was poor,the findings of this review should be interpreted with great caution,and our confidence in the results is low.A high quality RCT using objective outcomes should be performed on this topic.

关键词： acupuncture acupotomy tension-type headache systematic review meta-analysis

Growth and Magnetic Properties of Sol-Gel Derived Co-Doped ZnO Thin Film

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Journal of Rare Earths 2006年第Z1期24卷 59-63页

作者： Young Sung Kim Ki Chul Kim Won Pil tae Dae Ho yoon tae Seok Park Su Jeong Suh Advanced Material Process of Information Technology Sungkyunkwan University Suwon 440-746 Korea Cambridge-ETRI Joint R&D Centre Electronics and Telecommunications Research Institute Daejeon 305-350 Korea Ulsan Industry Promotion Techno Park Ulsan 683-804 Korea Advanced Material Process of Information Technology Sungkyunkwan University Suwon 440-746 Korea Advanced Material Process of Information Technology Sungkyunkwan University Suwon 440-746 Korea Advanced Material Process of Information Technology Sungkyunkwan University Suwon 440-746 Korea

Zn1-xCoxO films were grown on glass by sol-gel spin coating process. A homogeneous and stable Zn1-xCoxO sol was prepared by dissolving zinc acetate dihydrate, cobalt acetate tetrahydrate and aluminium chloride hexahydrate as solutes in solution of isopropanol and monoethanolamine. The films were postheated and vacuum annealed, and investigated for c-axis preferred orientation and electromagnetic properties. Zn1-xCoxO films with different Co concentrations were oriented well along the c-axis, especially the Zn1-xCoxO film with 10% Co(atom fraction) was highly c-axis oriented. The transmittance spectra show that Zn1-xCoxO films occur d-d transition and sp-d exchange interaction between Co2+ ions. The electrical resistivity of the films at 10% Co had the lowest value because the crystallite size became largest and the crystallinity of the c-axis was improved. X-ray photoelectron spectroscopy and alternating gradient magnetometer analyses indicated that no Co metal cluster was formed, and the ferromagnetism at room temperature appeared. The characteristics of the electrical resistivity and room temperature ferromagnetism of sol-gel derived Zn1-xCoxO films suggest a potential application of dilute magnetic semiconductor devices.

关键词： sol-gel Zn1-xCoxO thin film dilute magnetic semiconductor (DMS)