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Clinical Practice Guidelines and Experts’Consensuses for Treatment of Coronavirus Disease 2019(COVID-19)Patients with Chinese Herbal Medicine:A Systematic Review

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Chinese Journal of Integrative Medicine 2020年第10期26卷 786-793页

作者： LI Yu-xi LI Juan ZHANG Yue tian yan-ping ZHANG Yong-gang JIN Rong-jiang GUO yan Mike Clarke School of Acupuncture-Moxibustion and Tuina Chengdu University of Traditional Chinese MedicineChengdu(610032)China School of Health Preservation and Rehabilitation Chengdu University of Traditionai Chinese MedicineChengdu(610032)China West China Hospital Sichuan UniversityChengdu(610032)China Xiyuan Hospital China Academy of Chinese Medicine SciencesBeijing(100091)China Northern Ireland Clinical Trials Unit and Methodology Hub Centre for Public HealthQueen's University BelfastBelfastUK

Objective:To systematically review the clinical practice guidelines for the treatment of coronavirus disease 2019(COVID-19)patients with Chinese herbal medicine(CHM),summarize their recommendations and evaluate their ***:Electronic databases,websites of governments,academic associations or organizations for eligible guidelines were searched up to April *** were extracted to summarize recommendations for the use of Chinese herbal formulae and Chinese patent medicine(CPM)for COVID-19 *** methodological quality and reporting quality of the included guidelines were independently evaluated,using the Appraisal of Guidelines for REsearch and Evaluation(AGREE)Ⅱtool and Reporting Items for Practice Guidelines in healthcare(RIGHT)statement,***:Totally 45 guidelines were identififi ed:42(93%)suggested specific CM formulae for treating COVID-19 patients;and 35(78%)assigned patients diagnosed with COVID-19 to 4 stages(early,development,critical and recovery).The recommended formulae and CPMs for each stage with diverse syndrome types have been *** of the included guidelines were of low methodological quality,with only one achieving moderate quality of AGREEⅡ.The frequency with which the 35 items in the Reporting Items for Practice Guidelines in Healthcare(RIGHT)checklist were reported averaged 36.5%across the 45 ***:This systematic review has summarized current recommendations for treating COVID-19 patients with CHM and shows that the general quality of present guidelines is quite *** development of future guidelines should include increased awareness of the features of good quality guidelines.

关键词： coronavirus disease 2019 COVID-19 Chinese medicine herbal medicine clinical practice guideline systematic review

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Tomato mottle mosaic virus: Characterization, resistance gene effectiveness, and quintuplex RT-PCR detection system

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Journal of Integrative Agriculture 2022年第9期21卷 2641-2651页

作者： Carlos Kwesi TETTEY yan Zhi-yong MA Hua-yu ZHAO Mei-sheng GENG Chao tian yan-ping LI Xiang-dong Shandong Provincial Key Laboratory of Agricultural Microbiology College of Plant ProtectionShandong Agricultural University Tai'an 271018P.R.China

Tomato mottle mosaic virus(ToMMV), an economically important species of the genus Tobamovirus, causes significant loss in yield and quality of tomato fruits. Here, we identified the Shandong isolate of ToMMV(ToMMV-SD) collected from symptomatic tomato fruits in Weifang, Shandong Province of China. ToMMV-SD caused symptoms such as severe mosaic, mottling, and necrosis of tomato leaves, yellow spot and necrotic lesions on tomato fruits. The obtained full genome of ToMMV-SD was 6 399 nucleotides(accession number MW373515) and had the highest identity of 99.5% with that of isolate SC13-051 from the United States of America at the genomic level. The infectious clone of ToMMV-SD was constructed and induced clear mosaic and necrotic symptoms onto Nicotiana benthamiana leaves. Several commercial tomato cultivars, harboring Tm-2~2 resistance gene, and pepper cultivars, containing L resistance gene, were susceptible to ToMMV-SD. Plants of Solanum melongena(eggplant) and Brassica pekinensis(napa cabbage) showed mottling symptoms, while N. tabacum cv. Zhongyan 100 displayed latent infection. ToMMV-SD did not infect plants of N. tabacum cv. Xanthi NN, Brassica rapa ssp. chinensis(bok choy), Raphanus sativus(radish), Vigna unguiculata cv. Yuanzhong 28-2(cowpea), or Tm-2~2 transgenic N. benthamiana. A quintuplex RT-PCR system differentiated ToMMV from tomato mosaic virus, tomato brown rugose fruit virus, tobacco mosaic virus, and tomato spotted wilt virus, with the threshold amount of 0.02 pg. These results highlight the threat posed by ToMMV to tomato and pepper cultivation and offer an efficient detection system for the simultaneous detection of four tobamoviruses and tomato spotted wilt virus infecting tomato plants in the field.

关键词： host range multiplex RT-PCR resistance genes symptom Tobamovirus tomato mottle mosaic virus

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Biological and molecular characterization of tomato brown rugose fruit virus and development of quadruplex RT-PCR detection

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Journal of Integrative Agriculture 2021年第7期20卷 1871-1879页

作者： yan Zhi-yong ZHAO Mei-sheng MA Hua-yu LIU Ling-zhi yanG Guang-ling GENG Chao tian yan-ping LI Xiang-dong Shandong Provincial Key Laboratory of Agricultural Microbiology College of Plant ProtectionShandong Agricultural UniversityTai'an 271018P.R.China

Tomato brown rugose fruit virus(ToBRFV) is a novel tobamovirus firstly reported in 2015 and poses a severe threat to the tomato industry. So far, it has spread to 10 countries in America, Asia, and Europe. In 2019, ToBRFV was identified in Shandong Province(ToBRFV-SD), China. In this study, it was shown that ToBRFV-SD induced mild to severe mosaic and blistering on leaves, necrosis on sepals and pedicles, and deformation, yellow spots, and brown rugose necrotic lesions on fruits. ToBRFV-SD induced distinct symptoms on plants of tomato, Capsicum annumm, and Nicotiana benthamiana, and caused latent infection on plants of Solanum tuberosum, Solanum melongena, and N. tabacum cv. Zhongyan 102. All the 50 tomato cultivars tested were highly sensitive to ToBRFV-SD. The complete genomic sequence of ToBRFV-SD shared the highest nucleotide and amino acid identities with isolate IL from Israel. In the phylogenetic tree constructed with the complete genomic sequence, all the ToBRFV isolates were clustered together and formed a sister branch with tobacco mosaic virus(TMV). Furthermore, a quadruplex RT-PCR system was developed that could differentiate ToBRFV from other economically important viruses affecting tomatoes, such as TMV, tomato mosaic virus, and tomato spotted wilt virus. The findings of this study enhance our understanding of the biological and molecular characteristics of ToBRFV and provide an efficient and effective detection method for multiple infections, which is helpful in the management of ToBRFV.

关键词： host range identity quadruplex RT-PCR detection phylogenetic tree symptom tobamovirus tomato brown rugose fruit virus

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Dot-Blot Hybridization for Detection of Five Cucurbit Viruses by Digoxigenin-Labelled cDNA Probes

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Agricultural Sciences in China 2007年第12期6卷 1450-1455页

作者： MENG Juan GU Qin-sheng LIN Shi-ming PENG Bin LIU Li-feng tian yan-ping LI Li Zhengzhou Fruit Research Institute Chinese Academy of Agricultural Sciences Zhengzhou 450009 P.R.China Xiamen Entry-Exit Inspection and Quarantine Bureau Xiamen 361012 P.R.China

Dot-blot hybridization was applied in this paper to detect five viruses infecting cucurbitaceous crops, Zuccini yellow mosaic virus （ZYMV）, Watermelon mosaic virus （WMV）, Cucumber mosaic virus （CMV）, Papaya ringspot viruswatermelon strain （PRSV-W） and Squash mosaic virus （SqMV）, as a good alternative assay in seed health test and epidemiological and transgenic research. Digoxigenin-labelled cDNA probes of the five viruses were synthesized by PCR with the specific primers and applied in dot-blot hybridization to detect five viruses in crude extraction of the infected leaves. And three SqMV probes of different lengths （0.55, 1.6, and 2.7 kb, respectively） were designed to investigate the effect of hybridization. The results showed that the sensitivity for detecting the crude extraction of infected leaves by ZYMV, WMV, CMV, PRSV-W, and SqMV was down to 1：160, 1：160, 1：320, 1：160, and 1：320, respectively. Three SqMV probes of different length showed no differences on the sensitivity and specificity. The digoxigenin-labelled probes prepared by PCR could be used for accurate and rapid identification of 5 viruses infecting cucurbitaceous crops with good stabilities, sensitivities, specificity, and reproducibilifies.

关键词： PCR digoxigenin-labelled cDNA probe dot-blot hybridization ZYMV WMV CMV PRSV-W SqMV

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Ag-coated Long-period Fiber Grating

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Semiconductor Photonics and Technology 2005年第3期11卷 203-207,211页

作者： GU Zheng-tian XU yan-ping CHEN Jia-bi Lab. of Photo-electric Function. Films College of Sci. Shanghai University of Science and Technology Shanghai 200093 CHN

Based on coupled-mode theo ry , the eigenvalue equation of five-layered long-period fiber grating(LPFG) sens or with Ag film and gas-sensitive film overlays are firstly studied. The probl em of resolving complex eigenvalue equation on five-layered LPFG is analyzed, a nd the method of resolution is also given. Then the eigenvalue equation of three -layered metal cladding LPFG is analyzed, and the complex transcendental equati on is also discussed. The computing result shows that the coupling between the l ow-order EH modes and the core mode is much stronger than that between the low -order HE modes and the core mode.

关键词： Long-period fiber grating Gas sensors Metal cladding Complex eigenvalue equation

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Coupling constant of triple-clad long-period fiber grating

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Optoelectronics Letters 2006年第1期2卷 27-30页

作者： GU Zheng-tian XU yan-ping CHEN Jia-bi Laboratory of Photo-electric Functional Films University of Shanghai for Science and Technology Shanghai 200093 China

Based on the method of vector-field analysis, the relationship between the core-mode/cladding-mode coupling constant k1v-11^cl-co and mode order v is studied. It could be seen that the coupling constants of the l = 1 low-order HE cladding modes are larger than that of the l = 1 low-order EH cladding modes when v≤41. For cladding modes with v〉41 ,the coupling constants of the l= 1 low-order HE and EH modes are comparable to each other. The plotted local intensity curves of the six lowest-order （ l = 1 ） cladding modes show that the low-order HE modes have a larger proportion of intensity located in the core than the low- order EH modes. Further,the relationship between the coupling constant k1v-11^cl-co and the film refractive index as well as the film thickness is studied. The results indicate that the coupling constant changes monoton- ously with the film refractive index changing. As the film thickness increases, the coupling constant decreases slowly with irregularly changes in a certain region of the film thickness,which matches the experimental results of Nicholas D. R.

关键词：光学纤维光栅向量场耦合常量

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农民工职业选择影响因素的代际差异

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中国人口·资源与环境 2013年第1期23卷 81-88页

作者：田艳平中南财经政法大学公共管理学院湖北武汉430073 中国社会科学院人口与劳动经济研究所北京100732

由于第一代和新生代农民工出生和成长的时代背景不同,其思想、价值观念和行为上都有着明显差别。两代农民工无论是初次职业选择还是现职业选择,其职业结构、行业结构、职业目标和职业诉求、职业稳定性乃至当前工作条件、月均收入等方面... 详细信息

由于第一代和新生代农民工出生和成长的时代背景不同,其思想、价值观念和行为上都有着明显差别。两代农民工无论是初次职业选择还是现职业选择,其职业结构、行业结构、职业目标和职业诉求、职业稳定性乃至当前工作条件、月均收入等方面都呈现出较为明显的差异。对其初次职业选择影响因素以及现职业选择影响因素的多项Logistic回归表明,家庭因素较多地影响着老一代农民工的职业选择,他们因为家庭原因比较注重获得一定的、较稳定的收入。而在新生代农民工职业选择中,社会环境因素的影响较大,但也反映了其具有较强的家庭观念,并且比较关注工作条件。

关键词：职业选择影响因素代际差异农民工

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旧城改造对城市社会空间分异的影响——以武汉市为例

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人口学刊 2012年第6期34卷 72-80页

作者：田艳平中南财经政法大学公共管理学院湖北武汉430073

旧城改造对于塑造我国城市社会空间结构有着重要的影响,这种影响主要通过政府、企业和市民这三个主体的相互作用来体现。不同主体对不同社会群体的影响不同,使得不同社会群体在城市不同空间范围内聚集,从而导致城市社会空间分异。在运... 详细信息

旧城改造对于塑造我国城市社会空间结构有着重要的影响,这种影响主要通过政府、企业和市民这三个主体的相互作用来体现。不同主体对不同社会群体的影响不同,使得不同社会群体在城市不同空间范围内聚集,从而导致城市社会空间分异。在运用因子生态分析法界定2000年武汉市社会空间的基础上,通过建立多元线性回归模型,研究不同主体对城市社会空间分异的影响。研究发现政府对办事人员聚集区、外来人口聚集区、离退休人员聚集区、人口快速增长区的形成产生显著影响;企业对离退休人员聚集区、人口快速增长区和农业人口聚集区的形成具有一定的影响;而市民则对办事人员聚集区、离退休人员聚集区、人口快速增长区的形成具有一定的影响。这反映了旧城改造过程中政府为主导、企业和市民有限参与的现实状况。

关键词：旧城改造城市社会空间结构分异武汉

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A Contrastive Study of Honorific and Depreciatory Address Forms in Chinese,English and Japanese

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科技信息 2010年第27期 I0206-I0207页

作者：田艳萍青海师范大学外语系青海西宁810008

Honorific and depreciatory address forms, as an indispensable part of speech communication, occur in all languages. But due to the cultural diversity, different languages require different laws and regularities in the choice of them. This paper is firstly to make a contrastive analysis of honorific and depreciatory address forms in Chinese, English and Japanese, then explore the different basic values in Chinese, American and Japanese culture and discuss their influences on honorific and depreciatory address forms in the hope of a better understanding of their pragmatic and cultural differences and an avoidance of miscommunication in intercultural interactions.

关键词：英语教学教学方法阅读文化心理

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中部地区经济增长的趋同现象解析

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中南财经政法大学学报 2006年第5期 23-26页

作者：田艳平中南财经政法大学人口与区域研究中心湖北武汉430060

改革开放以来,我国中部地区在区域经济发展中的重要性不断下降,与东部等经济相对发达地区的差距增大,呈现出“边缘化”特征。其内部的经济联系主要表现出的是竞争而不是合作态势,使得其经济发展出现趋同现象。中部地区要摆脱“中部塌陷... 详细信息

改革开放以来,我国中部地区在区域经济发展中的重要性不断下降,与东部等经济相对发达地区的差距增大,呈现出“边缘化”特征。其内部的经济联系主要表现出的是竞争而不是合作态势,使得其经济发展出现趋同现象。中部地区要摆脱“中部塌陷”的困境,在适度竞争的同时更要加强分工与协作,加大对人力资本的投资力度,注重市场机制的培育与完善,充分发挥其综合优势,共同发展。

关键词：中部地区经济发展经济增长趋同

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