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Intrumer:A Multi Module Distributed Explainable IDS/IPS for Securing Cloud Environment

第十届全国心理学学术大会

作者： SATO,Tatsuya. TAk.HASHI,N. takeo,k. YAMAMOTO,T. PIAN,C. Ritsumeik.n University. k.oto 603-8577 Japan

Field interviews were conducted at Seoul, k.rea, in 2002. We visited 15 households in Seoul to interview parents and children about how their children get their allowances, for what purposes they use it, and how they manage it. In this paper, we try to analyze 5 families transcripts for understanding the beginning process of children’s receiving a fixed amount of pock.t money from their parents. All 6 children of 5 families didn’t receive a fixed amount of pock.t money at that time. Interestingly, one child gave up to receiving periodically, because she wanted to remove the burden of money management. So, we try to describe and explain the single X case with Trajectory Equifinality Model (TEM;Valsiner and Sato, 2005). If there is no appropriate theory, the case description have no value, This single case named X’s mother had never received pock.t money as a

关键词： pock.t money beginning process of receiving the pock.t money single case k.rean children

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Computers, Materials & Continua 2025年第1期82卷 579-607页

作者： Nazreen Banu A S.k.B.Sangeetha Department of Computer Science and Engineering SRM Institute of Science and TechnologyVadapalani CampusChennai600026Tamil NaduIndia

The increasing use of cloud-based devices has reached the critical point of cybersecurity and unwanted network.*** environments pose significant challenges in maintaining privacy and *** approaches,such as IDS,have been developed to tack.e these ***,most conventional Intrusion Detection System(IDS)models struggle with unseen cyberattack. and complex high-dimensional *** fact,this paper introduces the idea of a novel distributed explainable and heterogeneous transformer-based intrusion detection system,named INTRUMER,which offers balanced accuracy,reliability,and security in cloud settings bymultiplemoduleswork.ng together within *** traffic captured from cloud devices is first passed to the TC&TM module in which the Falcon Optimization Algorithm optimizes the feature selection process,and Naie Bayes algorithm performs the classification of *** selected features are classified further and are forwarded to the Heterogeneous Attention Transformer(HAT)*** this module,the contextual interactions of the network.traffic are tak.n into account to classify them as normal or malicious *** classified results are further analyzed by the Explainable Prevention Module(XPM)to ensure trustworthiness by providing interpretable *** the explanations fromthe classifier,emergency alarms are transmitted to nearby IDSmodules,servers,and underlying cloud devices for the enhancement of preventive *** experiments on benchmark.IDS datasets CICIDS 2017,Honeypots,and NSL-k.D were conducted to demonstrate the efficiency of the INTRUMER model in detecting network.trafficwith high accuracy for different *** outperforms state-of-the-art approaches,obtaining better performance metrics:98.7%accuracy,97.5%precision,96.3%recall,and 97.8%*** results validate the robustness and effectiveness of INTRUMER in securing diverse cloud environments against sophisticated cyber threats.

关键词： Cloud computing intrusion detection system transformers and explainable artificial intelligence(XAI)

Effects of P301L-TAU on post-translational modifications of microtubules in human iPSC-derived cortical neurons and TAU transgenic mice

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Neural Regeneration Research 2025年第8期20卷 2348-2360页

作者： Mohamed Aghyad Al k.bbani Christoph k.hler Hans Zempel Institute of Human Genetics Faculty of Medicine and University Hospital CologneUniversity of CologneCologneGermany Center for Molecular Medicine Cologne(CMMC) University of CologneCologneGermany Center Anatomy Department ⅡMedical FacultyUniversity of CologneCologneGermany

TAU is a microtubule-associated protein that promotes microtubule assembly and stability in the *** is missorted and aggregated in an array of diseases k.own as *** are essential for neuronal function and regulated via a complex set of post-translational modifications,changes of which affect microtubule stability and dynamics,microtubule interaction with other proteins and cellular structures,and mediate recruitment of microtubule-severing *** impairment of microtubule dynamics causes neuronal dysfunction,we hypothesize cognitive impairment in human disease to be impacted by impairment of microtubule *** therefore aimed to study the effects of a disease-causing mutation of TAU(P301L)on the levels and localization of microtubule post-translational modifications indicative of microtubule stability and dynamics,to assess whether P301L-TAU causes stability-changing modifications to *** investigate TAU localization,phosphorylation,and effects on tubulin post-translational modifications,we expressed wild-type or P301L-TAU in human MAPT-k. induced pluripotent stem cell-derived neurons(i Neurons)and studied TAU in neurons in the hippocampus of mice transgenic for human P301L-TAU(p R5 mice).Human neurons expressing the longest TAU isoform(2N4R)with the P301L mutation showed increased TAU phosphorylation at the AT8,but not the p-Ser-262 epitope,and increased polyglutamylation and acetylation of microtubules compared with endogenous TAU-expressing neurons.P301L-TAU showed pronounced somatodendritic presence,but also successful axonal enrichment and a similar axodendritic distribution comparable to exogenously expressed 2N4R-wildtype-TAU.P301L-TAU-expressing hippocampal neurons in transgenic mice showed prominent missorting and tauopathy-typical AT8-phosphorylation of TAU and increased polyglutamylation,but reduced acetylation,of microtubules compared with non-transgenic *** sum,P301L-TAU results in changes in micr

关键词： human induced pluripotent stem cell microtubules P301L pR5 mice TAU tauopathy tubulin code

Human endogenous retrovirus type-W and multiple sclerosis–related smoldering neuroinflammation

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Neural Regeneration Research 2025年第3期20卷 813-814页

作者： Joel Gruchot Laura Reiche Andrew Chan Robert Hoepner Patrick.k.ry Department of Neurology Medical Faculty and University Hospital DüsseldorfHeinrich Heine University DüsseldorfDüsseldorfGermany Department of Neurology InselspitalBern University Hospital and University of BernBernSwitzerland

Introduction to human endogenous retrovirus type-W(HERV-W): Genomic inheritance from the past includes retroviral sequences that have been stably incorporated into our genomes and account for up to 8% of human DNA.

关键词： endogenous inflammation Human

Nucleoside modified mRNA-lipid nanoparticles as a new delivery platform for the repair of the injured spinal cord

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Neural Regeneration Research 2025年第8期20卷 2311-2312页

作者： k.isztián Pajer Tamás Bellák.Antal Nógrádi Department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary

Spinal cord injury and treatment opportunities:The adult mammalian spinal cord has a very limited capacity for spontaneous regeneration due to various intrinsic molecular and cellular *** the spinal cord neurons have the capacity to regenerate their axons,the expression of growth inhibitory factors,lack.or suppression of proper guidance cues,and profound inflammatory responses do not permit successful regeneration(k.yeam et al.,2021).

关键词： injured capacity modified

Regression analysis of squeezing-induced hybrid nanofluid flow in Darcy-Forchheimer porous medium

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 193-208页

作者： k.MUHAMMAD M.SARFRAZ Department of Humanities and Sciences School of Electrical Engineering and Computer Science National University of Sciences and Technology Department of Mathematics Quaid-i-Azam University

This article presents a mathematical model addressing a scenario involving a hybrid nanofluid flow between two infinite parallel plates. One plate remains stationary, while the other moves downward at a squeezing velocity. The space between these plates contains a Darcy-Forchheimer porous medium. A mixture of water-based fluid with gold(Au) and silicon dioxide(Si O2) nanoparticles is formulated. In contrast to the conventional Fourier's heat flux equation, this study employs the Cattaneo-Christov heat flux equation. A uniform magnetic field is applied perpendicular to the flow direction, invok.ng magnetohydrodynamic(MHD) effects. Further, the model accounts for Joule heating, which is the heat generated when an electric current passes through the fluid. The problem is solved via NDSolve in MATHEMATICA. Numerical and statistical analyses are conducted to provide insights into the behavior of the nanomaterials between the parallel plates with respect to the flow, energy transport, and sk.n *** findings of this study have potential applications in enhancing cooling systems and optimizing thermal management strategies. It is observed that the squeezing motion generates additional pressure gradients within the fluid, which enhances the flow rate but reduces the frictional drag. Consequently, the fluid is pushed more vigorously between the plates, increasing the flow velocity. As the fluid experiences higher flow rates due to the increased squeezing effect, it spends less time in the region between the plates. The thermal relaxation, however, abruptly changes the temperature, leading to a decrease in the temperature fluctuations.

关键词： convective boundary condition Darcy-Forchheimer medium hybrid nanofluid Joule heating magnetohydrodynamic (MHD) numerical solution squeezing flow regression analysis O361 O175.2

2022年中国新生儿协作网极早产儿红细胞输注现况分析

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中华儿科杂志 2025年第1期63卷 55-61页

作者：莫艳钱爱民白瑞苗李淑涓玉小清王瑾 Lee Shoo k. 蒋思远韦秋芬周文浩国家儿童医学中心复旦大学附属儿科医院新生儿科上海南京医科大学附属儿童医院新生儿医疗中心南京西北妇女儿童医院新生儿科西安广西壮族自治区妇幼保健院新生儿医疗中心南宁加拿大西奈山医院母婴健康研究中心多伦多M5GX 广州市妇女儿童医疗中心新生儿医学中心广州

目的分析2022年中国新生儿协作网(CHNN)各单位极早产儿(出生胎龄<32周)红细胞输注治疗的状况。方法基于CHNN极早产儿队列的横断面研究, 纳入2022年生后24 h内收入CHNN 89家单位的6 985例极早产儿。排除合并严重先天畸形及放弃治疗或转至... 详细信息

目的分析2022年中国新生儿协作网(CHNN)各单位极早产儿(出生胎龄k.usk.l-WallisH检验及Mann-WhitneyU检验等进行组间比较, 采用Cochran-Armitage和Jonck.eere-Terpstra趋势检验进行不同出生胎龄及不同呼吸支持水平间的趋势检验。结果 6 985例极早产儿中男3 865例(55.3%), 出生胎龄为30.0(28.6, 31.0)周, 出生体重为(1 302±321)g。红细胞输注组3 617例(51.8%), 未输注组3 368例(48.2%)。出生胎龄<28、28～31周的极早产儿红细胞输注率分别为77.7%(893/1 150)、46.7%(2 724/5 835)。红细胞输注组极早产儿共接受9 616次红细胞输注, 输注时需有创呼吸支持的有2 459次(25.6%), 无创呼吸支持4 934次(51.3%), 无呼吸支持的有2 223次(23.1%)。因632次红细胞输注输血前血红蛋白未记录, 8 984次红细胞输注纳入分析。红细胞输注组母亲合并妊娠期高血压比例高于未输注组(χ2=10.73, P=0.001), 剖宫产出生、母亲产前激素应用比例均低于未输注组(χ2=12.00、12.93, 均P<0.001);与未输注组相比, 红细胞输注组患儿出生胎龄更小、出生体重更低, 小于胎龄、多胎以及第5分钟Apgar评分≤3分比例均更高, 女性、本院出生以及延迟脐带结扎比例均更低, 入院时生理稳定性转运风险指数评分更高(均P<0.05)。红细胞输注组极早产儿红细胞输注次数为2(1, 3)次, 首次红细胞输注时为18(8, 29)日龄, 首次红细胞输注前血红蛋白为97(86, 109)g/L。红细胞输注时≤7日龄的极早产儿有创呼吸支持、无创呼吸支持和无呼吸支持组接受红细胞输注前的血红蛋白水平差异无统计学意义(H=5.59, P=0.061);8～21以及≥22日龄的极早产儿不同呼吸支持状况下接受红细胞输注前的血红蛋白水平差异均有统计学意义(H=10.91、39.19, 均P<0.01)。8～21日龄、≥22日龄无呼吸支持的极早产儿阈值上红细胞输注分别为90.1%(264/293)、91.1%(1 578/1 732)。阈值上输血组极早产儿相比阈值下输血组发生坏死性小肠结肠炎的比例更高(χ2=10.59, P=0.001), 住院时间更长(Z=4.67, P<0.001)。结论 2022年CHNN纳入的极早产儿红细胞输注率较高, 接受红细胞输注前的血红蛋白水平普遍高于现有证据推荐的输注阈值。

关键词：婴儿, 早产红细胞输注重症监护病房, 新生儿

Enhancement of Photocatalytic and Antibacterial Activities of ZnO：Ag Nanopowders Through the Addition of Bamboo Charcoal： An Efficient Natural Adsorbent

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Acta Metallurgica Sinica(English Letters) 2017年第12期30卷 1249-1256页

作者： k. Nithiyadevi k. Ravichandran PG Research and Department of Physics AVVM Sri Pushpam College (Autonomous) Poondi Thanjavur Tamil Nadu 613 503 India Department of Physics Bharathidasan University Constituent College (Women) Orathanadu Tamil Nadu 614 625 India

This research article explains the removal of methylene blue （MB） and malachite green （MG） from aqueous solution using adsorption/photodegradation activity of ZnO：Ag/bamboo charcoal （BC） nanocomposite. In addition, the antibacterial studies of the prepared samples were tested against Staphylococcus aureus （S. aureus） Gram-positive and Escherichia coli （E. coli） Gram-negative bacteria by the well diffusion method. The ZnO：Ag/BC nanocomposite exhibits superior photocatalytic activity compared with ZnO：Ag. Remark.ble degradation efficiencies of 93.95% （MB） and 95.75% （MG） were recorded for ZnO：Ag/BC nanocomposite after 45 min. The degradation process follows a pseudo-first-order k.netics. The rate constant of ZnO：Ag/BC nanocomposite is two times greater than that of pristine ZnO nanopowder for the degradation of MB dye, while for MG dye degradation, it is three times. It is found that the ZnO：Ag/BC nanocomposite shows a higher rate of dye removal due to excellent adsorbing properties of bamboo charcoal （BC）. The ZnO：Ag/BC nanocomposite showed better antibacterial properties compared to ZnO：Ag. In this study, the samples were prepared using a simple and low-cost soft chemical route and they were characterized by optical, structural, surface morphological, antibacterial and photocatalytic properties. These characterization studies substantiate the discussions on the photocatalytic and antibacterial activities of the synthesized samples.

关键词： Bamboo charcoal Adsorbent ZnO Photocatalysis Antibacterial

MINIMAX PROGRAMMING UNDER GENERALIZED （p, r）-INVEXITY

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Journal of Systems Science & Complexity 2007年第4期20卷 501-508页

作者： S. k. MISHRA Shouyang WANG k. k. LAI Department of Mathematics Statistics and Computer Science College of Basic Sciences and Humanities G. B. Pant University of Agriculture and Technology Pantnagar-263 145 India Institute of Systems Science Academy of Mathematics and Systems Science Chinese Academy of Sciences Beijing 100080 China Department of Management Sciences City University of Hong Kong 83 Tat Chee Avenue Kowloon Hong Kong China

Minimax programming problems involving generalized （p, r）-invex functions are consid- ered. Parametric sufficient optimality conditions and duality results are established under the aforesaid assumptions on the obje... 详细信息

关键词： Duality minimax programming optimality conditions (p r)-invex functions.