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Development,validation,and transportability of several machine-learned,non-exercise-based VO_(2max)prediction models for older adults

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Journal of Sport and Health Science 2024年第5期13卷 611-620页

作者： Benjamin t.Schumacher michael J.Lamonte Andrea Z.LaCroix Eleanor m.Simonsick Steven P.Hooker Humberto Parada Jr. John Bellettiere Arun Kumar Herbert Wertheim School of Public Health and Human Longevity Science University of California San DiegoLa JollaCA 92093USA Department of Epidemiology and Environmental Health School of Public Health and Health ProfessionsUniversity at BuffaloState University of New YorkBuffaloNY 14214USA translational Gerontology Branch Intramural Research ProgramNational Institute on AgingNational Institutes of HealthBaltimoreMD 21225USA College of Health and Human Services San Diego State UniversitySan DiegoCA 92182USA Division of Epidemiology and Biostatistics School of Public HealthSan Diego State UniversitySan DiegoCA 92182USA University of California San Diego moores Cancer Center La JollaCA 92093USA Computer Science and Engineering and Halicioglu Data Science Institute University of California San DiegoLa JollaCA 92093USA

Background:there exist few maximal oxygen uptake(VO_(2max))non-exercise-based prediction equations,fewer using machine learning(mL),and none specifically for older *** direct measurement of VO_(2max)is infeasible in large epidemiologic cohort studies,we sought to develop,validate,compare,and assess the transportability of several mL VO_(2max)prediction ***:the Baltimore Longitudinal Study of Aging(BLSA)participants with valid VO2_(max)tests were included(n=1080).Least absolute shrinkage and selection operator,linear-and tree-boosted extreme gradient boosting,random forest,and support vector machine(SVm)algorithms were trained to predict VO_(2max)*** developed these algorithms for:(a)the overall BLSA,(b)by sex,(c)using all BLSA variables,and(d)variables common in aging ***,we quantified the associations between measured and predicted VO_(2max)and ***:the age was 69.0±10.4 years(mean±SD)and the measured VO_(2max)was 21.6±5.9 mL/kg/*** absolute shrinkage and selection operator,linear-and tree-boosted extreme gradient boosting,random forest,and support vector machine yielded root mean squared errors of 3.4 mL/kg/min,3.6 mL/kg/min,3.4 mL/kg/min,3.6 mL/kg/min,and 3.5 mL/kg/min,*** quartiles of measured VO_(2max)showed an inverse gradient in mortality *** VO_(2max)variables yielded similar effect estimates but were not robust to ***:measured VO_(2max)is a strong predictor of *** mL can improve the accuracy of prediction as compared to simpler approaches but estimates of association with mortality remain sensitive to *** studies should seek to reproduce these results so that VO_(2max),an important vital sign,can be more broadly studied as a modifiable target for promoting functional resiliency and healthy aging.

关键词： Cardiorespiratory fitness Prediction algorithms Epidemiology mortality

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硒来源及硒浓度对肉仔鸡生长性能及硒存留的影响

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饲料与畜牧（新饲料） 2007年第7期 49-49页

作者：高俊 I.Yoon t.m.werner J.m.Butler

用360只一日龄的JumboCornish杂交肉仔鸡进行为期6周的试验，以评估不同的硒来源及硒添加量对肉鸡生长性能和硒存留率的影响。肉仔鸡饲以玉米一豆粕型日粮，其中添加0（负对照）、来源于SelenosourceAF（硒酵母A，DiamondVm-山s，CedarR... 详细信息

用360只一日龄的JumboCornish杂交肉仔鸡进行为期6周的试验，以评估不同的硒来源及硒添加量对肉鸡生长性能和硒存留率的影响。肉仔鸡饲以玉米一豆粕型日粮，其中添加0（负对照）、来源于SelenosourceAF（硒酵母A，DiamondVm-山s，CedarRapids，IA）的0．1、0．2、0．3ppm硒、来源于Sel—Plex（酵母硒B，Alltech，Nicholasville，KY）的0．3ppm硒、来源于亚硒酸钠的0．3ppm硒。

关键词：生长性能硒浓度肉仔鸡硒存留率亚硒酸钠一日龄添加量硒酵母

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Quality of life and psychological distress in end-stage renal disease patients undergoing hemodialysis and transplantation

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World Journal of Nephrology 2024年第3期13卷 34-40页

作者： Emad A Shdaifat Firas t Abu-Sneineh Abdallah m Ibrahim Community Nursing Department Imam Abdulrahman Bin Faisal UniversityDammam 1982Saudi Arabia Department of Fundamental Nursing Imam Abdulrahman Bin Faisal UniversityDammam 1982Saudi Arabia

BACKGROUND Among diverse profound impacts on patients’quality of life(QoL),end-stage renal disease(ESRD)frequently results in increased levels of depression,anxiety,and *** replacement therapies such as hemodialysis(HD)and transplantation(tX)are intended to enhance QoL,although their ability to alleviate psychological distress remains *** research posits the existence of a significant correlation between negative emotional states and QoL among ESRD patients,with varying effects observed in HD and tX *** to examine the relationship between QoL and negative emotional states(depression,anxiety,and stress)and predicted QoL in various end-stage renal replacement therapy patients with *** this cross-sectional study included HD or tX patients in the Eastern Region of Saudi *** 36-item Short Form Survey and Depression Anxiety Stress Scale(DASS)was used for data collection,and correlation and regression analyses were *** the HD and tX transplantation groups showed statistically significant inverse relationships between QoL and DASS *** patients with high anxiety levels and less education scored low on the physical component summary(PCS).In addition,the results of the mental component summary(mCS)were associated with reduced *** with older transplant patients,tX patients’PCS scores were lower,and depression,stress,and negative working conditions were highly correlated with mCS *** the findings of this study revealed notable connections between well-being and mental turmoil experienced by individuals undergoing HD and *** PCS of HD patients is affected by heightened levels of anxiety and lower educational attainment,while the mCS of transplant patients is influenced by advancing age and elevated stress *** insights will contribute to a more comprehensive understanding of patient support.

关键词： Anxiety Depression End-stage renal disease Hemodialysis Patient Reported Outcome measures Psychological distress Quality of life Renal replacement therapy outcomes Saudi Arabia Stress

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Cognitive function among military veterans with StEm occupations

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military medical Research 2024年第2期11卷 308-310页

作者： Justin t.mcDaniel Kevin N.Hascup Erin R.Hascup Ugochukwu G.Ezigbo Amanda m.Weidhuner Harvey Henson David L.Albright Dale and Deborah Smith Center for Alzheimer's Research and trEatment(CARE) Southern Illinois University School of MedicineSpringfieldIL 62794USA StEm Education Research Center Southern Illinois UniversityCarbondaleIL 62901USA Department of Political Science The University of AlabamaTuscaloosaAL 35487USA

Dear Editor,there is limited research on the relationship between science,technology,engineering,and mathematics(StEm)occupational history and cognitive function in later life,especially among military veterans,who may be at greater risk for later-life cognitive *** study examines a nationally representative sample of military veterans to address this gap in knowledge.

关键词： Alzheimer's disease Veterans Science technology engineering and mathematics(StEm) Animal fluency test Dementia

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Landscape of global urban environmental resistome and its association with local socioeconomic and medical status

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Science China(Life Sciences) 2024年第6期67卷 1292-1301页

作者： Jun Wu Yige Hu michael H Perlin David Danko Jun Lu manuela Oliveira Johannes werner maria m Zambrano maria A Sierra Olayinka O Osuolale Paweł Łabaj Nicolás Rascovan Nur Hazlin Hazrin-Chong Soojin Jang Haruo Suzuki marina Nieto-Caballero Bharath Prithiviraj Patrick K H Lee Agnieszka Chmielarczyk Anna Różańska Yongxiang Zhao Lan Wang Christopher E mason tieliu Shi Center for Bioinformatics and Computational Biology and the Institute of Biomedical SciencesSchool of Life SciencesEast China Normal UniversityShanghai 200241China Department of Biology Program on Disease EvolutionUniversity of LouisvilleLouisville 40292USA Weill Cornell medicine New York 10065USA the Bin talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine New York 10065USA Department of Pulmonary medicine Shanghai Chest HospitalShanghai Jiao Tong UniversityShanghai 200025China i3S-Instituto de Investiga玢o e Inova玢o em Saúde Universidade do PortoPorto 4050-290Portugal Ipatimup-Instituto de Patologia e Imunologia molecular da Universidade do Porto Porto 4200-465Portugal Departamento de Biologia Faculdade de CiênciasUniversidade do PortoPorto 4050-290Portugal High Performance and Cloud Computing Group Zentrum für Datenverarbeitung(ZDV)Eberhard Karls University of TübingenW鋍hterstra遝7672074TübingenGermany Corporación Corpogen Research Center Bogotá110311Colombia Applied Environmental metagenomics and Infectious Diseases Research(AEmIDR) Department of Biological SciencesElizade UniversityIlara-Mokin 340271Nigeria maopolska Centre of Biotechnology Jagiellonian UniversityKraków 30-005Poland Aix-marseille Université Mediterranean Institute of OceanologyUniversitéde ToulonCNRSIRDUM 110Marseille 83041France Department of Biological Sciences and Biotechnology Faculty of Science and TechnologyUniversiti Kebangsaan Malaysia43600 UKM BangiSelangor Institut Pasteur Korea Seoul 13488Republic of Korea Faculty of Environment and Information Studies Keio UniversityFujisawaKanagawa 252-0882Japan University of Colorado at Boulder CivilEnvironmental and Architectural DepartmentBoulder 80303USA Brooklyn College of the City University of New York Brooklyn 11210USA School of Energy and Environment City University of Hong KongHong Kong 999077China Department of microbiology Faculty of MedicineJagiellonian UniversityKraków 30-005Poland Biological targeting Diagnosis and the

Antimicrobial resistance(AmR)poses a critical threat to global health and development,with environmental factors—particularly in urban areas—contributing significantly to the spread of antibiotic resistance genes(ARGs).However,most research to date has been conducted at a local level,leaving significant gaps in our understanding of the global status of antibiotic resistance in urban *** address this issue,we thoroughly analyzed a total of 86,213 ARGs detected within 4,728 metagenome samples,which were collected by the meta SUB International Consortium involving diverse urban environments in 60 cities of 27 countries,utilizing a deep-learning based *** findings demonstrated the strong geographical specificity of urban environmental resistome,and their correlation with various local socioeconomic and medical *** also identified distinctive evolutionary patterns of ARG-related biosynthetic gene clusters(BGCs)across different countries,and discovered that the urban environment represents a rich source of novel *** study provides a comprehensive overview of the global urban environmental resistome,and fills a significant gap in our knowledge of large-scale urban antibiotic resistome analysis.

关键词： urban environment metagenome antibiotic resistance resistance diversity biosynthetic gene clusters

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Superplasticity of fine-grained mg-10Li alloy prepared by severe plastic deformation and understanding its deformation mechanisms

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Journal of magnesium and Alloys 2024年第1期12卷 316-331页

作者： H.t.Jeong S.W.Lee W.J.Kim Department of materials Science and Engineering Hongik UniversityMapo-guSangsu-dong 72-1Seoul 121-791Republic of Korea

the superplastic behavior and associated deformation mechanisms of a fine-grained mg-10.1 Li-0.8Al-0.6Zn alloy(LAZ1011)with a grain size of 3.2μm,primarily composed of the BCCβphase and a small amount of the HCPαphase,were examined in a temperature range of 473 K to 623 *** microstructural refinement of this alloy was achieved by employing high-ratio differential speed *** best superplasticity was achieved at 523 K and at strain rates of 10^(-4)-5×10^(-4)s^(-1),where tensile elongations of 550±600%were *** the heating and holding stage of the tensile samples prior to tensile loading,a significant increase in grain size was observed at temperatures above 573 ***,it was important to consider this effect when analyzing and understanding the superplastic deformation behavior and *** the investigated strain rate range,the superplastic flow at low strain rates was governed by lattice diffusion-controlled grain boundary sliding,while at high strain rates,lattice diffusion-controlled dislocation climb creep was the rate-controlling deformation *** was concluded that solute drag creep is unlikely to *** the late stages of deformation at 523 K,it was observed that grain boundary sliding led to the agglomeration of theαphase,resulting in significant strain *** mechanism maps were constructed forβ-mg-Li alloys in the form of 2D and 3D formats as a function of strain rate,stress,temperature,and grain size,using the constitutive equations for various deformation mechanisms derived based on the data of the current tests.

关键词： magnesium-lithium alloy Superplasticity Severe plastic deformation Grain size Grain growth

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Colonic schistosomiasis mimicking cancer,polyp,and inflammatory bowel disease:Five case reports and review of literature

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World Journal of Gastrointestinal Endoscopy 2024年第8期16卷 472-482页

作者： Sebhatleab t mulate Abdulsemed m Nur Abel t tasamma Rodas t Annose Esmael m Dawud Kinfe W Ekubazgi Hailemichael D mekonnen Hidaya Y mohammed meron B Hailemeskel Shimelis A Yimer Department of Internal medicine Addis Ababa UniversityCollege of Health ScienceAddis Ababa 9086Ethiopia Department of Internal medicine Division of Gastroenterology and HepatologyAddis Ababa UniversityCollege of Health ScienceAddis Ababa 9086Ethiopia Department of Internal medicine St Paul’s Hospital Millennium Medical CollegeAddis Ababa 9086Ethiopia Department of Internal medicine Hawassa UniversityHawassa PO Box 05Ethiopia Department of Internal medicine St Paul’s Hospital Millennium Medical CollegeAddis Ababa 1271Ethiopia Department of Pathology Addis Ababa UniversityCollege of Health ScienceAddis Ababa 9086Ethiopia Department of Pathology St Paul’s Hospital Millennium Medical CollegeAddis Ababa 1271Ethiopia Department of Pathology Ethio Tebib General HospitalAddis Ababa 1111Ethiopia

BACKGROUND Schistosomiasis,officially named as a neglected tropical disease by the World Health Organization,is a serious parasitic disease caused by trematode flukes of the genus *** is a common infectious disease,endemic in more than 78 *** disease can involve various organs and poses far-reaching public health *** SUmmARY Here,we present a series of five patients with variable presentations:an asymptomatic patient who was diagnosed with colonic schistosomiasis upon screening colonoscopy;2 patients with clinical suspicion of colonic cancer;and 2 patients with a clinical diagnosis of inflammatory bowel *** patients were subsequently confirmed to have colonic schistosomiasis after colonoscopy and histopathologic *** clinical manifestations,colonoscopy features and histologic findings of the patients are *** of the patients showed significant clinical improvement following administration of oral *** Intestinal schistosomiasis can present with features mimicking other gastrointestinal *** disease should be a diagnostic consideration in patients who live in or have traveled to endemic areas.

关键词： Schistosomiasis Schistosoma Colon Polyp Ethiopia Case report

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the Soft X-ray Imager(SXI)on the SmILE mission

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Earth and Planetary Physics 2024年第1期8卷 5-14页

作者： S.Sembay A.L.Alme D.Agnolon t.Arnold A.Beardmore A.Belén Balado margeli C.Bicknell C.Bouldin G.Branduardi-Raymont t.Crawford J.P.Breuer t.Buggey G.Butcher R.Canchal J.A.Carter A.Cheney Y.Collado-Vega H.Connor t.Crawford N.Eaton C.Feldman C.Forsyth t.Frantzen G.Galgóczi J.Garcia G.Y.Genov C.Gordillo H-P.Gröbelbauer m.Guedel Y.Guo m.Hailey D.Hall R.Hampson J.Hasiba O.Hetherington A.Holland S-Y.Hsieh m.W.J.Hubbard H.Jeszenszky m.Jones t.Kennedy K.Koch-mehrin S.Kögl S.Krucker K.D.Kuntz C.Lakin G.Laky O.Lylund A.martindale J.miguel mas Hesse R.Nakamura K.Oksavik N.Østgaard H.Ottacher R.Ottensamer C.Pagani S.Parsons P.Patel J.Pearson G.Peikert F.S.Porter t.Pouliantis B.H.Qureshi W.Raab G.Randal A.m.Read N.m.m.Roque m.E.Rostad C.Runciman S.Sachdev A.Samsonov m.Soman D.Sibeck S.Smit J.Søndergaard R.Speight S.Stavland m.Steller tianRan Sun J.thornhill W.thomas K.Ullaland B.Walsh D.Walton C.Wang S.Yang School of Physics and Astronomy University of LeicesterLeicesterLE17RHUK Space Park Leicester University of LeicesterLeicesterLE17RHUK mullard Space Science Laboratory University College LondonDorkingRH56NTUK Centre for Electronic Imaging Open UniversityMilton KeynesMK76 AAUK Birkeland Centre for Space Science Department of Physics and TechnologyUniv.of BergenN-5007 BergenNorway University of Vienna A-1010 ViennaAustria Space Research Institute Austrian Academy of SciencesA-8042 GrazAustria National Institute of Aerospace technology MadridSpain EStEC European Space Agency2201 AZ NoordwijkNetherlands State Key Laboratory of Space Weather National Space Science CentreBeijing 100190China University of Applied Sciences and Arts Northwestern Switzerland CH-5210 WindischSwitzerland Koegl Space GmbH CH-8157 DielsdorfSwitzerland Space Acoustics GmbH CH-8157 DielsdorfSwitzerland Zurich University of Applied Sciences 8400 WinterhurSwitzerland Genov Solutions N-5172 LoddefjordNorway Stm Engineering N-5165 LaksevagNorway John Hopkins University Applied Physics Laboratory MD 20723USA NASA/Goddard Space Flight Centre MD 20771USA Center for Space Physics Boston UniversityBostonMA 02215USA Department of theoretical Physics and Astrophysics Masaryk University60177 BrnoCzech Republic Institute of Physics E¨otvo¨s Lor´and University1053 BudapestHungary Aerospace Information Research Institute Chinese Academy of SciencesBeijing 100045China Centro de Astrobiologia(CAB) CSIC-INTAMadridSpain

the Soft X-ray Imager(SXI)is part of the scientific payload of the Solar wind magnetosphere Ionosphere Link Explorer(SmILE)*** is a joint science mission between the European Space Agency(ESA)and the Chinese Academy of Sciences(CAS)and is due for launch in *** is a compact X-ray telescope with a wide field-of-view(FOV)capable of encompassing large portions of Earth’s magnetosphere from the vantage point of the SmILE *** is sensitive to the soft X-rays produced by the Solar Wind Charge eXchange(SWCX)process produced when heavy ions of solar wind origin interact with neutral particles in Earth’s *** provides a mechanism for boundary detection within the magnetosphere,such as the position of Earth’s magnetopause,because the solar wind heavy ions have a very low density in regions of closed magnetic field *** sensitivity of the SXI is such that it can potentially track movements of the magnetopause on timescales of a few minutes and the orbit of SmILE will enable such movements to be tracked for segments lasting many *** is led by the University of Leicester in the United Kingdom(UK)with collaborating organisations on hardware,software and science support within the UK,Europe,China and the United States.

关键词： Soft X-ray Imaging micropore optics large area CCD

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Effect of Fluidic Diode on Performance of Unidirectional Impulse turbine

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Journal of thermal Science 2024年第3期33卷 807-814页

作者： DODDAmANI Hithaish ABDUS Samad mANABU takao SHINYA Okuhara m m ASHRAFUL Alam Department of Ocean Engineering Indian Institute of Technology MadrasChennai600036India Department of mechanical Engineering National Institute of TechnologyMatsue CollegeShimane6908518Japan Center of Support Practical Education National Institute of TechnologyMatsue CollegeShimane6908518Japan Department of transportation Engineering Osaka Sangyo UniversityDaito5748530Japan

A pair of unidirectional turbines(Ut)can operate in oscillatory airflow without additional ***,this arrangement suffers from poor flow rectification.A fluidic diode(FD)offers variable hydrodynamic resistance based on the flow direction,and this can be coupled with Ut to improve flow *** this work,a numerical investigation on the effect of FD with Ut is presented using the commercial fluid dynamics software ANSYS Fluent 16.1 with k-ωSSt turbulence closure *** domains of Ut and FD are numerically validated individually with experimental ***,both are coupled to obtain the combined effect,and these results are compared with the analytical *** was observed that coupling FD with Ut improved the unit's performance at the lower flow coefficient(t its performance decreased as the flow coefficient *** to the diode's presence,fluid leaving the turbine experiences higher resistance at a higher flow coefficient,which decreases the overall performance of the combined unit.

关键词： wave energy oscillating water column unidirectional impulse turbine fluidic diode flow rectification

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Why and how to use the SeqCode

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mLife 2024年第1期3卷 1-13页

作者： Wiliam B.Whitman maria Chuvochina Brian P.Hedlund Konstantinos t.Konstantinidis marike Palmer Luis m.Rodriguez-R lain Sutcliffe Fengping Wang Deparment of microbioogy University of GeorgiaAthensGeorgiaUAA Schoolof Chemistry and molecular Biosciences Australian CentreforEogenomicsThe Universty of QueenslandSt LuciaAustralia University of Nevada Las Vegas Las VegasNevadaUSA Schol of Civil and Environmental Engineering and School of Biological SciencesGeorgia Institute of TechnologyAtlantaGeorgiaUSA Department of microbiology University of ManitobaWinnipegManitobaCanada School of Life Sciences University of Nevada Las VegasLas VegasNevadaUSA Department of microbiology and Digital Science Center(DiSC) University of InnsbruckInnsbruckAustria Faculty of Health&Life Sciences Northumbria UniversityNewcastle upon TyneUK School of Oceanography International Center for Deep Life InvestigationShanghai Jiao Tong UniversityShanghaiChina

the SeqCode,formally called the Code of Nomenclature of Prokaryotes Described from Sequence Data,is a new code of nomenclature in which genome sequences are the nomenclatural types for the names of prokaryotic *** similar to the International Code of Nomenclature of Prokaryotes(ICNP)in structure and rules of priority,it does not require the deposition of type strains in international culture ***,it allows for the formation of permanent names for uncultured prokaryotes whose nearly complete genome sequences have been obtained directly from environmental DNA as well as other prokaryotes that cannot be deposited in culture *** the diversity of uncultured prokaryotes greatly exceeds that of readily culturable prokaryotes,the SeqCode is the only code suitable for naming the majority of prokaryotic *** start date of the SeqCode was January 1,2022,and the online Registry(https://***)was created to ensure valid publication of *** SeqCode recognizes all names validly published under the ICNP before *** that date,names validly published under the SeqCode compete with ICNP names for *** a result,species can have only one name,either from the SeqCode or ICNP,enabling effective communication and the creation of unified taxonomies of uncultured and cultured *** SeqCode is administered by the SeqCode Committee,which is comprised of the SeqCode Community and elected administrative *** with an interest in the systematics of prokaryotes is encouraged to join the SeqCode Community and participate in the development of this resource.

关键词： genome sequences metagenome-assembled genomes nomenclature SeqCode

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