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Event.relat.d pot.nt.al invest.gat.on of different.neural pat.ways for face and pat.ern percept.ons in t.e human brain

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Journal of Biomedical Science and Engineering 2012年第4期5卷 170-175页

作者： Ryozo Aoki Shinnya Okamot. t.kahiro Sakimot. Kazuki Yoshida Hit.shi sasaki Depart.ent.of Elect.icit. and Elect.onics College of Industrial Technology Amagasaki Japan Depart.ent.of Elect.icit. and Elect.onics College of Industrial Technology Amagasaki Japan Email: ryo Depart.ent.of Physiology Graduate School of Medicine Osaka University Suita Japan

t.o different.pat.ways in t.e brain have been implicat.d in t.e human visual percept.on process. One involves emot.onal cognit.on of face feat.res, and t.e ot.er involves spat.al pat.ern cognit.on. In t.e present.st.dy, we used t.e event.relat.d pot.nt.al (ERP) met.od t. examine t.mporal act.vat.on of t.e percept.on pat.ways at.a fine t.me resolut.on of less t.an 10 ms. Four elect.odes were at.ached ont. t.eir heads at.O2, Pz, t., and Fz, and ERP waveforms were observed on each elect.ode simult.neously. Nine port.ait. of act.esses and 9 geomet.ical figures were chosen respect.vely, and present.d on a CRt.display in random order. t.e t.o t.pes of figures elicit.d different.responses. For port.ait., t.e first.significant.N100 peak appeared on Pz and Fz, but.not.O2. For pat.erns, it.st.rt.d at.N130 on O2. A significant.response t. port.ait. most.y appeared on t., Pz, and Fz, and t. pat.erns on O2, Pz, and Fz.

关键词： Influenza Visual-Percept.on Cognit.on-Syst.m Limbic-Syst.m Oddball-Met.od ERP N100 N170 P300

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离化簇的淀积

表面技术 1980年第1期 61-66页

作者： t.t.kagi I·Yamada A·sasaki 张祥生南光机器厂

本文介绍一种淀积形式.这就是:材料在坩埚内汽化,然后它的蒸汽喷出喷嘴,在电子束力的作用下进入高真空.由喷嘴喷出的蒸汽局部地凝聚成簇.这些簇由于电子轰击而电离,并且向基片加速.它们的淀积膜显示出良好的附着力和大晶粒尺寸.例如Cu... 详细信息

本文介绍一种淀积形式.这就是:材料在坩埚内汽化,然后它的蒸汽喷出喷嘴,在电子束力的作用下进入高真空.由喷嘴喷出的蒸汽局部地凝聚成簇.这些簇由于电子轰击而电离,并且向基片加速.它们的淀积膜显示出良好的附着力和大晶粒尺寸.例如Cu——玻璃、Si——Si等的淀积.

关键词：真空淀积显微照片衍射图簇离子动能基片温度加速电压电子轰击离化淀积速率

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离化簇的淀积

包装工程 1980年第1期 61-66页

作者： t.t.kagi I·Yamada A·sasaki 张祥生南光机器厂

本文介绍一种淀积形式。这就是:材料在坩埚内汽化,然后它的蒸汽喷出喷嘴,在电子束力的作用下进入高真空。由喷嘴喷出的蒸汽局部地凝聚成簇。这些簇由于电子轰击而电离,并且向基片加速。它们的淀积膜显示出良好的附着力和大晶粒尺寸。例... 详细信息

本文介绍一种淀积形式。这就是:材料在坩埚内汽化,然后它的蒸汽喷出喷嘴,在电子束力的作用下进入高真空。由喷嘴喷出的蒸汽局部地凝聚成簇。这些簇由于电子轰击而电离,并且向基片加速。它们的淀积膜显示出良好的附着力和大晶粒尺寸。例如Cu——玻璃、Si——Si等的淀积。

关键词：真空淀积簇离子电子轰击离子源粒子源离化淀积速率

作物中多种有机磷农药的简便提纯和气相色谱测定

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农药译丛 1990年第2期12卷 54-57,49页

作者： K.sasaki t.Suzuki Y.Sait. 苏小川日本国立卫生科学研究所

有机磷农药(OP农药)已被广泛使用,目前在日本注册的就有40余种。因此,研究作物中有机磷农药多成份残留分析的方法,是日常必不可少的工作。常用的分析方法是用活性炭柱层析进行提纯,但这种方法耗时长,而且对植物色素和其他干扰物未必都... 详细信息

有机磷农药(OP农药)已被广泛使用,目前在日本注册的就有40余种。因此,研究作物中有机磷农药多成份残留分析的方法,是日常必不可少的工作。常用的分析方法是用活性炭柱层析进行提纯,但这种方法耗时长,而且对植物色素和其他干扰物未必都能彻底除去。在氨基甲酸酯分析中,笔者发现了一种由NH_4Cl和H_3PO_4组成的凝结剂对作物萃取物的提纯具有理想的效果。目前,配备火焰光度检测器(FPD)、氮磷检测器(NPD)或电子捕获检测器(ECD)的毛细管柱气相色谱法已应用于各种有机磷农药的检测。

关键词：有机磷农药提纯气相色谱

Expression of leukot.iene B4 recept.r 1 defines funct.onally dist.nct.DCs t.at.cont.ol allergic skin inflammat.on

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Cellular & Molecular Immunology 2021年第6期18卷 1437-1449页

作者： t.moaki Koga Fumiyuki sasaki Kazuko Saeki Soken t.uchiya t.shiaki Okuno Mai Ohba t.kako Ichiki Sat.shi Iwamot. Hirot.ugu Uzawa Keiko Kit.jima Chikara Meno Eri Nakamura Norihiro t.da Yoshinori Fukui Junichi Kikut. Masaru Ishii Yukihiko Sugimot. Mit.uyoshi Nakao t.kehiko Yokomizo Depart.ent.of Biochemist.y Juntendo University Graduate School of MedicineTokyo113-8421Japan Depart.ent.of Medical Cell Biology Institute of Molecular Embryology and GeneticsKumamoto UniversityKumamoto860-0811Japan Depart.ent.of Cell Signaling Graduate School of Medical and Dental SciencesTokyo Medical and Dental UniversityTokyo113-8510Japan Depart.ent.of Pharmaceut.cal Biochemist.y Graduate School of Pharmaceutical SciencesKumamoto UniversityKumamoto862-0973Japan Depart.ent.of Development.l Biology Graduate School of Medical SciencesKyushu UniversityFukuoka812-8582Japan Laborat.ry of Genome Research Research Institute for Diseases of Old AgeJuntendo University Graduate School of MedicineTokyo113-8421Japan Division of Immunogenet.cs Department of Immunobiology and NeuroscienceMedical Institute of BioregulationKyushu UniversityFukuoka812-8582Japan Depart.ent.of Immunology and Cell Biology Graduate School of Medicine and Frontier BiosciencesOsaka UniversityOsaka565-0871Japan

Leukot.iene B4(Lt.4)recept.r 1(BLt.)is a chemot.ct.c G prot.in-coupled recept.r expressed by leukocyt.s,such as granulocyt.s,macrophages,and act.vat.d t.*** t.ere is growing evidence t.at.BLt. plays crucial roles in immune responses,it. role in dendrit.c cells remains largely ***,we ident.fied novel DC subset. defined by t.e expression of BLt.,namely,BLt.hi and BLt.lo *** also found t.at.BLt.hi and BLt.lo DCs different.ally migrat.d t.ward Lt.4 and CCL21,a lymph node-homing chemoat.ract.nt.*** generat.ng Lt.4-producing enzyme Lt.4H knockout.mice and CD11c promot.r-driven Cre recombinase-expressing BLt. condit.onal knockout.BLt. cKO)mice,we showed t.at.t.e migrat.on of BLt.hi DCs exacerbat.d allergic cont.ct.*** t.anscript.me analysis revealed t.at.BLt.hi DCs preferent.ally induced t.1 different.at.on by upregulat.ng IL-12p35 expression,whereas BLt.lo DCs accelerat.d t.cell proliferat.on by producing ***,t.e dat. reveal an unexpect.d role for BLt. as a novel DC subset.marker and provide novel insight. int. t.e role of t.e Lt.4-BLt. axis in t.e spat.ot.mporal regulat.on of dist.nct.DC subset..

关键词： Lt.4 BLt. dendrit.c cells inflammat.on lipid mediat.r

Effect.of Side Chain of Oligot.iophene Derivat.ves on Bulk Het.rojunct.on St.uct.re in Organic Phot.volt.ic Devices

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Advances in Mat.rials Physics and Chemist.y 2013年第2期3卷 185-190页

作者： Kenichi sasaki Yosei Shibat. Ming Lu Yuji Yoshida Reiko Azumi Yasukiyo Ueda Graduat. School of Engineering Kobe University Hyogo Japan Int.rdisciplinary Graduat. School of Science and Engineering Tokyo Institute of Technology Kanagawa Japan Nat.onal Inst.t.t. of Advanced Indust.ial Science and t.chnology (AISt. Ibaraki Japan

t.e effect.of t.e molecular st.uct.re on phot.volt.ic performance was invest.gat.d by comparing t.o t.pes of act.ve layers. One is an act.ve layer formed by sexit.iophene (6t. and C60 molecules which don’t.have side chains. Anot.er one is an act.ve layer formed by a,ω-bis(2-hexyldecyl)sexit.iophene (BHD6t. and [6,6]-phenyl-C61-but.ric acid met.yl est.r (PCBM) molecules which have side chains. t.e 6t.C60 act.ve layer exhibit.d an excessive cryst.llizat.on of 6t. which led t. t.e low phot.volt.ic performance. In t.e BHD6t.PCBM act.ve layer, t.e cryst.llizat.on of BHD6t.was suppressed. t.e cryst.llizat.on of BHD6t.was also easily cont.olled by t.ermal annealing, which led t. improved phot.volt.ic performance.

关键词： Organic Phot.volt.ic Cells Sext.iophene Bulk Het.rojunct.on Morphology

Response of low act.ve GLP-1 like subst.nces t. t.st.meal in obese Japanese pat.ent. wit. t.pe 2 diabet.s mellit.s compared wit. obese cont.ols wit. normal glucose t.lerance

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Journal of Diabet.s Mellit.s 2012年第3期2卷 265-271页

作者： Kyuzi Kamoi Nobumasa Ohara t.moo Ikarashi You Shinozaki Kazuo Furukawa Hideo sasaki Cent.r of Diabet.s and Endocrine & Met.bolism Disease Nagaoka Red Cross Hospital Nagaoka Japan Depart.ent.of Endocrinology and Met.bolism Niigata University Niigata Japan Diabet.s Cent.r Niigata Medical Center Niigata Japan

Background: A secret.on of plasma act.ve GLP-1 (p-act.ve GLP-1) aft.r ingest.on of breakfast.t.st.meal (t.) is decreased in obese European pat.ent. wit. t.pe 2 diabet.s mellit.s (t.DM). However, t.ere was no significant.difference in pact.ve GLP-1 secret.on following t. bet.een obese Japanese pat.ent. wit. t.DM and cont.ols. t.e findings indicat. t.e difference may be due t. different.races or diet.ry’s cust.ms of subject.. Aims: We examined whet.er pact.ve GLP-1 is t.uly affect.d by t. in obese Japanese pat.ent. (n = 24, group 1) and obese cont.ols (n = 12, group 2). Met.ods: Glucose (PG), insulin (s-IRI), C-pept.de (s-CPR) and act.ve GLP-1 like subst.nces (p-act.ve GLP-1-S) levels in blood were measured 0, 30 and 60 min aft.r t.. Obese Japanese pat.ent. wit. mean 9 years of diabet.s had micro- and macro-vascular dist.rbances and were t.eat.d wit. diet. exercise and/or oral drugs for hyperglycemia. Result.: t.ere was no significant.difference in sex, age or BMI bet.een groups. Means HbA1c and PG were significant.y higher in group 1 t.an in group 2. t.ere were no significant.differences in means of basal s-IRI, HOMA-R and s-CPR bet.een groups. However, means of HOMA-β, insulinogenic index, post.randial s-IRI, s-CPR and p-act.ve GLP-1-S or p-act.ve GLP-1-S/PG values aft.r t. were significant.y lower in group 1 t.an in group 2. Conclusions: t.ese result. indicat. t.at.a response of p-act.ve GLP-1-S aft.r t. in obese Japanese pat.ent. wit. t.DM was decreased and secret.on of GLP-1 relat.ve t. PG was impaired. t.e met.od of enhancing funct.on of act.ve GLP-1 may be useful for t.eat.ent.in some of pat.ent. wit. diabet.s mellit.s.

关键词： Act.ve GLP-1 t.st Meal BMI Obesit. Japanese t.pe 2DM

Hist.logical Findings of Bone Marrow Lesions on Magnet.c Resonance Images in Pat.ent. wit. Varus Knee Ost.oart.rit.s

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Open Journal of Ort.opedics 2014年第12期4卷 327-334页

作者： t.kehiko Sugit. t.momaro Kawamat. t.shimi Aizawa Akira sasaki Naohisa Miyat.ke t.keshi Uehara Depart.ent.of Ort.opaedic Surgery Tohoku Orthopaedic Clinic Sendai Japan Depart.ent.of Ort.opaedic Surgery Sendai Orthopaedic Hospital Sendai Japan Depart.ent.of Ort.opaedic Surgery Tohoku University Graduate School of Medicine Sendai Japan

Bone marrow lesions (BMLs) on magnet.c resonance (MR) images in knee ost.oart.rit.s pat.ent. are considered t. predict.t.e severit. and progression of t.e disease. We evaluat.d t.e hist.logical findings of BMLs on MR images of t.e subchondral area of t.e medial femoral condyle in varus ost.oart.rit.c knees. In 24 pat.ent. wit. varus knee ost.oart.rit.s who underwent.t.t.l knee art.roplast. (t.A), sagit.al t.- and t.-weight.d MR images of t.e affect.d knee were acquired before t.A. During t.A, resect.d bone pieces from t.e dist.l medial femoral condyle were obt.ined. Sagit.al specimens obt.ined from t.e cent.r of t.e bone pieces were hist.logically examined. t.ent. pat.ent. had BMLs. Hist.logical findings of BMLs in t.e subchondral area showed various feat.res, such as fibrovascular t.ssue, cyst.format.on, act.ve bone remodeling wit. bone format.on and bone resorpt.on, and hyaline cart.lage. BMLs were not.found in four pat.ent.;hist.logical findings of t.ese pat.ent. showed normal bone marrow t.ssue wit. normal-t.ickness t.abeculae. Subchondral bony end plat. in knees wit. BMLs was usually t.in or dest.oyed, while t.at.wit.out.BMLs was t.ick or normal. t.e condit.on of t.e subchondral bony end plat. would explain t.e differences in t.e severit. and progression bet.een pat.ent. wit. or wit.out.BMLs.

关键词： Knee Ost.oart.rit.s Magnet.c Resonance Images Hist.logy Bone Marrow Lesion

Decreased levels of plasma adiponect.n associat.d wit. increased risk of colorect.l cancer

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World Journal of Gast.oent.rology 2010年第10期16卷 1252-1257页

作者： Sayaka Ot.ke Hiroaki t.keda Shoichiro Fujishima t.dahisa Fukui t.mohiko Orii t.keshi Sat. Yu sasaki Shoichi Nishise Sumio Kawat. Depart.ent.of Gast.oent.rology Yamagata University Faculty of Medicine Division of Endoscopy Yamagata University Hospital

AIM:t. invest.gat. t.e associat.on bet.een adiponect.n levels and risk of colorect.l adenoma and cancer (early and advanced).MEt.ODS: A cross-sect.onal st.dy in a cohort.of hospit.l-based pat.ent. was conduct.d bet.een January 2004 and March 2006 at.Yamagat. Universit. Hospit.l. Male subject., who had colorect.l t.mors det.ct.d by endoscopic examinat.on, were enrolled according t. inclusion and exclusion crit.ria. Based on t.e t.fact.r of t.e t.M syst.m, int.aepit.elial carcinoma and submucosally invasive carcinoma were def ined as early cancer, and invasion int. t.e muscularis propria or deeper was defined as advanced cancer. t.e plasma levels of glucose, insulin, t.t.l cholest.rol, t.iglyceride, high sensit.vit. C-react.ve prot.in, insulin like growt. fact.r (IGF)-1, IGF binding prot.in-3, adiponect.n, lept.n, and resist.n were measured. Each fact.r level was designat.d low or high, and t.e risk of adenoma or cancer was est.mat.d by univariat. and mult.variat. logist.c regression ***: We enrolled 124 male subject. (47 wit. adenoma, 34 wit. early cancer, 17 wit. advanced cancer, and 26 wit.out.t.mors as cont.ols). In pat.ent. wit. adenoma, high t.iglyceride and low adiponect.n were associat.d wit. a significant.increase in t.e odds rat.o (OR) by univariat. analysis. Only a low adiponect.n level was relat.d t. increased adenoma risk, wit. an adjust.d OR for low level (t. high (≥11 μg/mL) of 5.762 (95% confidence int.rval (CI):1.683-19.739, P=0.005). In t.e pat.ent. wit. early cancer, high body mass index, high t.iglyceride, and low adiponect.n were associat.d wit. a significant.increase in OR in univariat. analysis. Imult.variat. analysis, only low adiponect.n was significant.y associat.d wit. early cancer, wit. an adjust.d OR of 4.495 (95% CI:1.090-18.528, P=0.038). However, in pat.ent. wit. advanced cancer, low adiponect.n was not.recognized as a significant.risk fact.r for advanced ***: A decreased level of adiponect.n is st.

关键词： Adenoma Early colorect.l cancer Met.bolic syndrome Adipokines Colonoscopy Resist.n Lept.n Body mass index