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Outcomes of patients older than 75 years with non-metastatic prostate cancer

作     者:Yoshiyasu Amiya Yasutaka Yamada Masahiro Sugiura Makoto Sasaki Takayuki Shima Noriyuki Suzuki Hiroomi Nakatsu Shino Murakami Jun Shimazaki 

作者机构:Department of UrologyAsahi General HospitalAsahiJapan Department of UrologyGraduate School of MedicineChiba UniversityChibaJapan 

出 版 物:《Asian Journal of Urology》 (亚洲泌尿外科杂志(英文))

年 卷 期:2017年第4卷第2期

页      面:102-106页

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主  题:Prostate cancer Elderly Androgen deprivation Non-metastatic prostate cancer Radiation therapy 

摘      要:Objective:Prostate cancer in elderly patients was formerly treated with androgen deprivation *** the latter of the 1990s new technologies were introduced into treatments,then strategies have *** aimed to observe the outcomes of elderly patients treated during transition period and compare each stage with ***:During 2008 and 2010,255 patients with prostate cancer older than 75 years were sequentially *** exception of patients with bone and/or visceral metastasis,outcomes of 199 patients with localized and locally advanced stages were *** records were obtained by the end of ***:In total,122(61%),28(14%),37(19%)and 12(6%)of patients were in stages T1c-T2a,T2b-c,T3 and T4,*** generally presented with abnormal screening or lower urinary tract ***-one percent of patients received androgen deprivation therapy as monotherapy and 22% of the radiation-treated patients added androgen deprivation *** in stage T1c-T2a and T2b-c showed a favorable *** cancer death appeared in patients with T3 and T4 during observation ***-seven percent of patients died from prostate cancer-independent complications:pneumonia,heart disease,and brain vascular *** is similar to that of Japanese elderly male *** remarkable side effects from androgen deprivation therapy were noticed.

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