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Bi-based superconduct.rs fabricat.d in high magnet.c fields

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中国有色金属学会会刊：英文版 2006年第B01期16卷 11-19页

作者： LU XY A. nagata K. SUGAWARA K. WAt.NABE t. NOJIMA Facult. of Engineering and Resource Science Akita University Akita 010-8502 Japan Inst.t.t. for Mat.rials Research Tohoku University Sendai 980-8577 Japan Cent.r for Low t.mperat.re Science Tohoku University Sendai 980-8577 Japan

t.e microst.uct.re and superconduct.ng propert.es of Bi-2223 superconduct.r fabricat.d in high magnet.c fields were invest.gat.d. t.e result. shows t.at.t.e Bi-2212 grains wit. t.eir c-axis parallel t. t.e magnet.c field were formed aft.r t.e part.al-melt.ng and solidificat.on in 8 t.magnet.c field, and t.ansformed int. t.e Bi-2223 grains wit. c-axis alignment.during t.e furt.er sint.ring process at.840 ℃ wit.out.magnet.c field. t.e conversion of Bi-2212 grains t. Bi-2223 grains has t.e heredit. in grain alignment. t.e mixed st.uct.res of t.e Bi-2223 and t.e Bi-2212 grains wit. t.eir c-axis parallel t. t.e magnet.c field are formed in samples sint.red at.850?855 ℃ in 10 t.magnet.c field. When sint.red in 10 t.below 845 ℃, a high proport.on of Bi-2223 phase is obt.ined, however no preferred orient.t.on is observed. t.e Bi-2223 grains wit. t.eir c-axis parallel t. t.e axial direct.on of t.e vert.cal t.be furnace are formed not.only on t.e surface, but.also in t.e cent.r of t.e sample sint.red at.850 ℃ for 120 h in a 15 ℃/cm t.mperat.re gradient.wit.out.magnet.c field. Moreover, t.e samples sint.red in t.e t.mperat.re gradient.and in a 10 t.magnet.c field have a st.onger c-axis alignment.of Bi-2223 phase.

关键词：铋基超导体制造铋-2223 磁场显微结构

Preoperat.ve evaluat.on of colorect.l cancer using Ct.colonography, MRI, and PEt.Ct

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World Journal of Gast.oent.rology 2014年第45期20卷 16964-16975页

作者： Shigeyoshi Kijima t.kahiro Sasaki Koichi nagata Kenichi Ut.no Alan t.Lefor Hideharu Sugimot. Depart.ent.of Radiology Jichi Medical University Depart.ent.of Surgery Jichi Medical University

Imaging st.dies are a major component.in t.e evaluat.on of pat.ent. for t.e screening,st.ging and surveillance of colorect.l *** review present. commonly encount.red findings in t.e diagnosis and st.ging of pat.ent. wit. colorect.l cancer using comput.d t.mography(Ct.colonography,magnet.c resonance imaging(MRI),and posit.on emission t.mography(PEt./Ct.*** colonography provides import.nt.informat.on for t.e preoperat.ve assessment.of t.*** deformit.es are associat.d wit. muscular or subserosal *** node met.st.ses from colorect.l cancer oft.n present.wit. *** is superior t. det.ct.calcified ***-dimensional Ct.t. image t.e vascular anat.my facilit.t.s laparoscopic surgery.t.st.ging of rect.l cancer by MRI is an est.blished modalit. because MRI can diagnose rect.l wall laminar st.uct.re.N st.ging in pat.ent. wit. colorect.l cancer is st.ll challenging using any imaging *** is more accurat. t.an Ct.for t.e evaluat.on of liver ***/Ct.colonography isvaluable in t.e evaluat.on of ext.a-colonic and hepat.c ***/Ct.colonography is useful for obst.uct.ng colorect.l cancers t.at.cannot.be t.aversed ***/Ct.colonography is able t. localize synchronous colon cancers proximal t. t.e obst.uct.on ***,t.ere is no definit. evidence t. support.t.e rout.ne clinical use of PEt.Ct.colonography.

关键词： Colorect.l cancer Preoperat.ve evaluat.on t.st.ging N st.ging Liver met.st.sis Magnet.c resonance imaging Comput.d t.mography colonography Posit.on emission t.mography

Performance est.mat.on of bi-direct.onal t.rbines in wave energy plant.

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Journal of t.ermal Science 2007年第4期16卷 346-352页

作者： S.Anand V.Jayashankar S.nagata K.t.yot. M.t.kao t.Set.guchi Depart.ent.of Elect.ical Engineering IIT MadrasIndia IOES Saga UniversityJapan Depart.ent.of Mechanical Engineering Matsue National College of TechnologyJapan Depart.ent.of Mechanical Engineering Saga UniversityJapan

Oscillat.ng wat.r column （OWC） based wave energy plant. have been designed wit. several t.pes of bidirect.onal t.rbines for convert.ng pneumat.c power t. shaft.power. Impulse t.rbines wit. linked guide vanes and fixed guide vanes have been t.st.d at.t.e Indian Wave Energy plant. t.is was aft.r init.al experiment.t.on wit. Well＇s t.rbines. In cont.ast.t. t.e Well＇s t.rbine which has a linear damping charact.rist.c, impulse t.rbines have non-linear damping. t.is has an import.nt.effect.in t.e overall energy conversion from wave t. wire. Opt.mizing t.e wave energy plant.requires a t.rbine wit. linear damping and good efficiency over a broad range of flow coefficient. t.is work describes how such a design can be made using fixed guide vane impulse t.rbines. t.e Indian Wave Energy plant.is used as a case st.dy.

关键词： Bidirect.onal t.rbine different.al pressure flow rat. impulse t.rbine

Device-assist.d t.act.on met.ods in colorect.l endoscopic submucosal dissect.on and opt.ons for difficult.cases

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World Journal of Gast.oint.st.nal Endoscopy 2023年第4期15卷 265-272页

作者： Mit.uru nagata Depart.ent.of Endoscopy Shonan Fujisawa Tokushukai HospitalFujisawa 251-0041KanagawaJapan

Endoscopic submucosal dissect.on(ESD)procedure has a longer procedure t.me and higher perforat.on rat. t.an endoscopic mucosal resect.on owing t. t.chnical complicat.ons,including a poor field of vision and inadequat. t.nsion for t.e submucosal dissect.on *** t.act.on devices were developed t. secure t.e visual field and provide adequat. t.nsion for t.e dissect.on *** randomized cont.olled t.ials demonst.at.d t.at.t.act.on devices reduce colorect.l ESD procedure t.me compared wit. convent.onal ESD(C-ESD),but.t.ey had limit.t.ons,including a single-cent.r *** CONNECt.C t.ial was t.e first.mult.cent.r randomized cont.olled t.ial comparing t.e C-ESD and t.act.on device-assist.d ESD(t.ESD)for colorect.l *** t.e t.ESD,one of t.e device-assist.d t.act.on met.ods(S-O clip,clip-wit.-line,and clip pulley)was chosen according t. t.e operat.r’s *** median ESD procedure t.me(primary endpoint.was not.significant.y different.bet.een C-ESD and *** lesions≥30 mm in diamet.r or in cases t.eat.d by nonexpert.operat.rs,t.e median ESD procedure t.me t.nded t. be short.r in t.ESD t.an in *** t.ESD did not.reduce ESD procedure t.me,t.e CONNECt.C t.ial result. suggest.t.at.t.ESD is effect.ve for larger lesions and nonexpert.operat.rs in colorect.l *** wit. esophageal and gast.ic ESD,colorect.l ESD has some difficult.es,including poor endoscope maneuverabilit.,which may be associat.d wit. prolonged ESD procedure t.me.t.ESD may not.effect.vely improve t.ese issues,but.a balloon-assist.d endoscope and underwat.r ESD may be promising opt.ons and t.ese met.ods can be combined wit. t.ESD.

关键词： Endoscopic submucosal dissect.on t.act.on t.act.on direct.on Balloonassist.d endoscope Underwat.r endoscopic submucosal dissect.on

Edgewort. Approximat.on of a Finit. Sample Dist.ibut.on for an AR(1) Model wit. Measurement.Error

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Open Journal of St.t.st.cs 2012年第4期2卷 383-388页

作者： Shuichi nagata Depart.ent.of Mat.emat.cal Sciences Kwansei Gakuin University Sanda Japan

In t.is paper, we consider t.e finit. sample propert. of t.e ordinary least.squares (OLS) est.mat.r for an AR(1) model wit. measurement.error. We present.t.e Edgewort. approximat.on for a finit. dist.ibut.on of OLS up t. O(t./2). We int.oduce an inst.ument.l variable est.mat.r t.at.is consist.nt.in t.e presence of measurement.error. Finally, a simulat.on st.dy is conduct.d t. assess t.e t.eoret.cal result. and t. compare t.e finit. sample performances of t.ese est.mat.rs.

关键词： Edgewort. Expansion OLS Measurement Error Inst.ument.l Variables Est.mat.r

Analysis of Bell-t.pe Experiment. and It. Local Realism

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Journal of Applied Mat.emat.cs and Physics 2015年第7期3卷 898-902页

作者： Koji nagata t.dao Nakamura Depart.ent.of Physics Korea Advanced Institute of Science and Technology Daejeon Korea Depart.ent.of Informat.on and Comput.r Science Keio University Yokohama Japan

We invest.gat. t.e violat.on fact.r of t.e original Bell-Mermin inequalit.. Unt.l now, we have used an assumpt.on t.at.t.e result. of measurement.are . In t.is case, t.e maximum violat.on fact.r is as follows: and . t.e quant.m predict.ons by n-part.t. Greenberger-Horne-Zeilinger st.t. violat. t.e Bell-Mermin inequalit. by an amount.t.at.grows exponent.ally wit. n. Recent.y, a new measurement.t.eory is proposed [K. nagata and t. Nakamura, Int.rnat.onal Journal of t.eoret.cal Physics, 49, 162 (2010)]. t.e values of measurement.out.ome are . Here we use t.e new measurement.t.eory. We consider a mult.part.t. GHZ st.t.. We use t.e original Bell-Mermin inequalit.. It.t.rns out.t.at.t.e original Bell-Mermin inequalit. is sat.sfied irrespect.ve of t.e number of part.cles. In t.is case, t.e maximum violat.on fact.r is as follows: and . t.us t.e original Bell-Mermin inequalit. is sat.sfied by t.e new measurement.t.eory. We propose t.e following conject.re: All t.e t.o-ort.ogonal-set.ings experiment.l correlat.on funct.ons admit.local realist.c t.eories irrespect.ve of a st.t. if we use t.e new measurement.t.eory.

关键词： Quant.m Nonlocalit. Quant.m Measurement t.eory

Granulysin and it. clinical significance as a biomarker of immune response and NK cell relat.d neoplasms

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World Journal of Hemat.logy 2014年第4期3卷 128-137页

作者： Masayuki Nagasawa Kazuyuki Ogawa Kinya nagata Norio Shimizu Depart.ent.of Hemat.logy Oncologyand ImmunologyTokyo Bay Urayasu/Ichikawa Medical CenterChiba 279-0001Japan Bio Medical Laborat.ries Inc. Research and Development CenterSaitama 602-0841Japan t.kyo Medical and Dent.l Universit. Post Graduate SchoolDepartment of VirologyTokyo 113-8519Japan

Granulysin is a cyt.t.xic granular prot.in t.at.was ident.fied from human t.cells by using t.e gene subt.act.on met.od in 1987. Based on it. amino acid homology, granulysin belongs t. t.e saposin-like prot.in family. t.e bioact.ve 9-k Da form of granulysin is processed from t.e 15-k Da pro-product.in t.e cyt.plasmic granules. It.is expressed in CD8-posit.ve αβt.cells 5 d aft.r mit.genic st.mulat.on and const.t.t.vely in nat.ral killer(NK) cells and γδt.cells, alt.ough regulat.on of it. expression has not.yet.been precisely det.rmined. t.e 9-k Da granulysin form has ant.-microbial act.vit. against.microorganisms such as bact.ria, fungi, mycobact.ria and parasit.s, as well as t.moricidal act.vit. against.some t.mors at.1-10 μmol/L concent.at.ons. Granulysin is secret.d in bot. Ca-dependent.and-inde-pendent.manners. In sera, only t.e 15-k Da form is det.ct.ble and is expect.d t. be a biomarker for immune pot.ncy, acut. viral infect.on, ant.-t.mor immune react.on, acut. graft.vs host.disease, and NK cell associat.d neoplasm.

关键词： Granulysin Saposin-like prot.in family Nat.ral killer cell Cyt.t.xic t lymphocyt.

Soluble St. prot.in inhibit. LPS st.mulat.on on monocyt.-derived dendrit.c cells

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Cellular & Molecular Immunology 2012年第5期9卷 399-409页

作者： Akihisa nagata Naoki t.kezako Hiroyuki t.memot. Hiromi Oht.-Ozaki Sat.shiOht. Shin-ichi t.minaga Ken Yanagisawa Depart.ent.of Biochemist.y School of Medicine Jichi Medical University Shimotsuke-shi Tochigi Japan Hemat.logy Division National Hospital Organization Disaster Medical Center of Japan Tachikawa-shi Tokyo Japan

St. prot.in is a soluble splicing variant.of St.L prot.in, which is t.e recept.r for int.rleukin-33 （IL-33）. Previously, we report.d t.at.soluble St. suppressed t.e signal t.ansduct.on of lipopolysaccharide （LPS） and cyt.kine product.on in monocyt.c cells. t. invest.gat. whet.er or not.t.is inhibit.ry effect.occurs in dendrit.c cells, which are t.e key players in innat. and adapt.ve immunit., human monocyt.-derived dendrit.c cells were pre-t.eat.d wit. soluble St. prot.in before LPS st.mulat.on. Alt.ough soluble St. did not.at.enuat. t.e LPS-induced mat.rat.on of dendrit.c cells, pre-t.eat.ent.wit. soluble St. suppressed cyt.kine product.on and inhibit.d LPS signaling. Moreover, t.e proliferat.on of naive t.cells was inhibit.d significant.y by soluble St. pre-t.eat.ent. IL-33 had lit.le effect.on t.e cyt.kine product.on of immat.re monocyt.-derived dendrit.c cells. Furt.ermore, soluble St. prot.in was int.rnalized int. dendrit.c cells, suggest.ng t.at.soluble St. prot.in act. by a noncanonical mechanism ot.er t.an t.e sequest.at.on of IL-33.

关键词： dendrit.c cells LPS signal t.ansduct.on St. t.R4

Successful t.eat.ent.of Life-t.reat.ning Cerebral Bleeding Associat.d wit. Disseminat.d Int.avascular Coagulat.on Using Recombinant.Human Soluble t.rombomodulin in a Pat.ent.wit. Mixed Phenot.pe Acut. Leukemia wit. t.(9;22) (q34;q11.2);&lt.i&gt.Bcr-Abl1&lt./i&gt.

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Int.rnat.onal Journal of Clinical Medicine 2013年第1期4卷 52-57页

作者： Naoki t.kezako t.kashi Ishii Akihisa nagata Naohiro Sekiguchi Sat.shi Not. Akiyoshi Miwa Depart.ent.of Hemat.l- ogy National Center for Global Health and Medicine Tokyo Japan Depart.ent.of Hemat.logy National Hospital Organization Disaster Medical Center Tachikawa Tokyo Japan

Recent.y, mixed phenot.pe acut. leukemia (MPAL) wit. t.(9;22) (q34;q11.2);bcr-abl1 was described as one kind of acut. leukemia of ambiguous lineage in t.e 2008 World Healt. Organizat.on Classificat.on of t.mors of Hemat.poiet.c and Lymphoid t.ssues. However, t.eat.ent.st.at.gy remains difficult.for t.is uncommon MPAL. In addit.on, t.is t.pe of MPAL is at.high risk of t.mor lysis syndrome (t.S) because of high chemo-sensit.vit.. Here, we report.a MPAL wit. t.(9;22) (q34;q11.2);bcr-abl1 case t.at.suffered from life-t.reat.ning cerebral bleeding associat.d wit. disseminat.d int.avascular coagulat.on (DIC) wit. t.S aft.r bcr-abl posit.ve acut. lymphoblast.c leukemia (ALL) t.pe induct.on t.erapy who was successfully t.eat.d wit. recombinant.human t.rombomodulin (rht.). t.is case reached complet. remission wit.out.addit.ve cerebral bleeding. In conclusion, bcr-abl posit.ve ALL t.pe induct.on t.erapy was effect.ve for MPAL wit. t.(9;22) (q34;q11.2);bcr-abl1 and rht. was effect.ve against.DIC wit. t.S.

关键词： Mixed Phenot.pe Acut. Leukemia wit. t (9 22) (q34 q11.2) Bcr-Abl1 Recombinant Human Soluble t.rombomodulin Imat.nib Disseminat.d Int.avascular Coagulat.on