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Advances in the management of peritoneal mesothelioma

World Journal of Gastroenterology 2014年第33期20卷 11700-11712页

作者： ali raza Wei-Ching Huang Kazuaki Takabe Division of Surgical Oncology Department of Surgery Virginia Commonwealth University School of Medicine and Massey Cancer Center Richmond VA 23298-0011 United States

Malignant peritoneal mesothelioma(PM) is an infrequent disease which has historically been associated with a poor prognosis. Given its long latency period and non-specific symptomatology, a diagnosis of PM can be suggested by occupational exposure history, but ultimately relies heavily on imaging and diagnostic biopsy. Early treatment options including palliative operative debulking, intraperitoneal chemotherapy, and systemic chemotherapy have marginally improved the natural course of the disease with median survival being approximately one year. The advent of cytoreduction(CRS) with hyperthermic intraperitoneal chemotherapy(HIPEC) has dramatically improved survival outcomes with wide median survival estimates between 2.5 to 9 years; these studies however remain largely heterogeneous, with differing study populations, tumor biology, and specific treatment regimens. More recent investigations have explored extent of cytoreduction, repeated operative intervention, and choice of chemotherapy but have been unable to offer definitive conclusions. CRS and HIPEC remain morbid procedures with complication rates ranging between 30% to 46% in larger series. Ac-cordingly, an increasing interest in identifying molecular targets and developing targeted therapies is emerging. Among such novel targets is sphingosine kinase 1(SphK1) which regulates the production of sphingosine-1-phosphate, a biologically active lipid implicated in various cancers including malignant mesothelioma. The known action of specific SphK inhibitors may warrant further exploration in peritoneal disease.

关键词： Peritoneal mesothelioma Mesothelioma Hyperthermic intraperitoneal chemotherapy Cytore-duction Sphingosine kinase Sphingosine-1-phosphate FTY720

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TiC-Maraging stainless steel composite:microstructure, mechanical and wear properties

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Rare Metals 2006年第6期25卷 630-635页

作者： Akhtar Farid Khadijah ali Shah syed Javid Askari School of Material Science and Engineering University of Science and Technology Beijing Beijing 100083 China

Particulate TiC reinforced 17-4PH and 465 maraging stainless steel matrix composites were processed by conventional powder metallurgy （P/M）. TiC-maraging stainless steel composites with theoretical density 〉97% were produced using conventional P/M. The microstructure, and mechanical and wear properties of the composites were evaluated. The microstructure of the composites consisted of （core-rim structure） spherical and semi-spherical TiC particles depending on the wettability of the matrix with TiC particles. In TiC-maraging stainless steel composites, 465 stainless steel binder phase showed good wettability with TiC particles. Some microcracks appeared in the composites, indicating the presence of tensile stresses in the composites produced during sintering. The typical properties, hardness, and bend strength were reported for the composites. After heat treatment and aging, an increase in hardness was observed. The increase in hardness was at- tributed to the aging reaction in maraging stainless steel. The specific wear behavior of the composites strongly depends on the content of TiC particles and their interparticle spacing, and on the heat treatment of the maraging stainless steel.

关键词： TiC-maraging stainless steel composites aging wear powder metallurgy microcracks

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Insights of numerical simulations of magnetohydrodynamic squeezing nanofluid flow through a channel with permeable walls

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Propulsion and Power Research 2021年第4期10卷 412-420页

作者： Kashif ali Khan Nauman raza Mustafa Inc Department of Mathematics University of Engineering and TechnologyLahorePunjab54000Pakistan Department of Mathematics University of the PunjabLahorePunjab54000Pakistan Department of Computer Engineering Biruni UniversityIstanbulTurkey Department of Mathematics Firat UniversityElazig23119Turkey

An analysis related to the transport of nanofluid that is confined in a channel between two orthogonal permeable walls will be investigated with the help of two numerical *** the aid of the reasonable similarity changeover;the said model will be shaped into the desired non-linear equation whose behavior will be explained analytically as well as graphically where the functioning of three disparate variables such as magnetic parameter,permeable Reynold number,and channel permeable ratio will be explained *** said model has been controlled by the homotopy analysis method(HAM)and then,compared through an efficient numerical method named shooting method(ShM).The profiles show that increases in the magnetic parameter decline the nanofluid flow velocity,whereas magnitude-wise raise is shown in each axial velocity *** radial profile raises while getting variation in wall expansion parameter from negative to *** the entire domain,the rate of change in velocity description enhances at the center while reduces at the *** the outcomes disclose that the wall permeable ratio has a significant impact on the *** the zero value of wall ratio refers to the particular type that Terrill has discussed.

关键词： Homotopy analysis method Orthogonal walls Nanofluid Similarity changeover Wall ratio factor

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Enhanced urease inhibition activity of Ag nanomaterials capped with N-substituted methyl 5-acetamido-β-resorcylate

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Progress in Natural Science:Materials International 2019年第2期29卷 129-137页

作者： syeda Sohaila Naz Muhammad raza Shah Nazar Ul Islam syed Sartaj Alam Nanosciences and Technology Department National Centre for Physics Quaid-i-Azam University Campus ICCBS H.E.J.Research Institute of Chemistry University of Karachi Institute of Chemical Sciences University of Peshawar Sarhad University of Science and Information Technology Department of Plant Pathology The University of AgriculturePeshawar Pakistan

Medically, bacterial ureases are important virulent factors and are used for treatment of peptic ulcers and urinary tones. Reported urease inhibitors are associated with various side effects including antibiotic resistance as a major one. Still there is an urgent need to synthesize new urease inhibitors. In this context we have synthesized new urease inhibitor i.e. AgL that is composed of Ag nanomaterials capped with N-substituted methyl 5-acetamido-β-resorcylate(L). The conjugation of L to silver was confirmed through FTIR, UV–vis and TEM *** silver nanomaterials(Ag) were also prepared. The stability of AgL nanostructures was determined against various parameters(temperature, high salt concentration, pH) and found to be stable. The in vitro antimicrobial(antibacterial, antifungal), enzyme inhibition(xanthine oxidase, urease, carbonic anhydrase, α-chymotrypsin,cholinesterase) and antioxidant activities of AgL were investigated and compared with Ag, L and standard *** comparison to other bioactivities, AgL shows statistically enhanced selective enzyme inhibition activity against urease enzyme. Urease inhibition activity of AgL was significantly greater than standard drug(thiourea),L and Ag. On a per weight basis, AgL required about 11–18 times less amount of L for inhibition of urease enzyme.

关键词： β-Resorcylic acid N-Substituted methyl 5-acetamido-β-resorcylate Silver nanomaterials Enhanced urease inhibition activity

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Fingerprint matching,spoof and liveness detection:classification and literature review

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Frontiers of Computer Science 2021年第1期15卷 179-196页

作者： syed Farooq ali Muhammad Aamir KHAN Ahmed Sohail ASLAM Department of Software Engineering University of Management and TechnologyLahore 54770Pakistan Department of Informatics and Systems University of Management and TechnologyLahore 54770Pakistan Department of Computer Science University of Management and TechnologyLahore 54770Pakistan

Fingerprint matching,spoof mitigation and liveness detection are the trendiest biometric techniques,mostly because of their stability through life,uniqueness and their least risk of *** recent decade,several techniques are presented to address these challenges over well-known *** study provides a comprehensive review on the fingerprint algorithms and techniques which have been published in the last few *** divides the research on fingerprint into nine different approaches including feature based,fuzzy logic,holistic,image enhancement,latent,conventional machine learning,deep learning,template matching and miscellaneous *** these,deep learning approach has outperformed other approaches and gained significant attention for future *** reviewing fingerprint literature,it is historically divided into four eras based on 106 referred papers and their cumulative citations.

关键词： computer society template matching fingerprint recognition survey deep learning machine learning

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The Ability of Some Aquatic and Terrestrial Plants to Purify Domestic Wastewater

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Phyton-International Journal of Experimental Botany 2023年第8期92卷 2245-2260页

作者： Abida Kausar Noreen Zahra Humaira Kiran Sadia Asim Abid raza ali raza Department of Botany Government College Women UniversityFaisalabad38000Pakistan Department of Botany University of AgricultureFaisalabad38040Pakistan Department of Chemistry Government College Women UniversityFaisalabad38000Pakistan Department of Agronomy Muhammad Nawaz Shareef University of AgricultureMultan66000Pakistan College of Agriculture Fujian Agriculture and Forestry UniversityFuzhou350002China

The study aimed to evaluate the ability of some terrestrial and aquatic plants for wastewater puriﬁ*** plants can remove pollutants from wastewater by consuming and accumulating various contaminants in different parts of *** aquatic and terrestrial plants(Rosa sinensis,Typha latifolia,Ocimm bacilicum,Azolla pinnata,and Salvinia molesta)which have the ability to decrease water pollution were utilized in this *** capability offive different species of plants was investigated by measuring chemical oxygen demand(COD),biological oxygen demand(BOD),electrical conductivity(EC),total dissolved solids(TDS),and pH of the *** this research,some aquatic and terrestrial plants were transplanted in wastewater plastic pots containing domestic wastewater with different ratios of 50%and 100%.Then,after 30 days,the physiological and biochemical parameters of plants were calculated to observe the effect of wastewater on *** revealed higher chlorophyll and carotenoids in typha plants treated with 100%*** highest percentage of elimination in BOD(65%),COD(27%),TDS(72%),EC(83%),and pH(6.8%)was noted with the use of typha and ***,total soluble sugars,total free amino acids,and total proteins were found maximum in the hibiscus plant as compared to the other plants under 100%and 50%domestic wastewater treatment,while typha and ocimum showed lower values of these parameters irrespective of wastewater ***,the COD,BOD,TDS,EC,and pH trend was higher in 100%wastewater as compared to 50%*** into account the accumulation capacity of the tested plants especially typha can be efﬁciently used for the treatment of domestic wastewater.

关键词： Biological oxygen demand chemical oxygen demand domestic wastewater aquatic plants terrestrial plants

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In-cylinder in-depth combustion investigation for a heavy-duty diesel engine

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Propulsion and Power Research 2024年第3期13卷 335-359页

作者： Anam ali Khalid Saifullah syed Centre for Advanced Studies in Pure and Applied Mathematics(CASPAM) Bahauddin Zakariya University(BZU)MultanPunjab 60800Pakistan

This present study is part of the design improvement process of a specified high torque low-speed *** work aims at carrying out an in-depth analysis of in-cylinder combustion,mesh sensitivity,and engine performance at supercharge conditions to provide a foundation for the design improvement process of the given *** computational fluid dynamic(CFD)simulations are carried out on a 3D sector from-130°to 130°crank angle(CA)by employing appropriate models to represent the different physical and chemical processes and using the finite volume method for solving the governing differential *** extensive investigation has been carried out for the choice of base mesh size and the number of local and temporal refinements to capture the phenomena happening in the combustion chamber at diverse temporal and local *** present results have been validated against available literature experimental and simulation *** field variables and the wellknown four phases of combustion have been studied for gaining in-depth insight into these *** average pressure,mean temperature,heat release rate(HRR),integrated heat release rate(IHRR),and emissions of CO_(2),CO,NOx,HC and soot are presented to assess the quality of *** performance analysis has been done in terms of combustion ef-ficiency,gross work,power,torque,and integrated mean effective pressure(IMEP).The base mesh of 1.4 mm may be an appropriate choice during the injection and combustion process spanning throughout around 40CA from the start of injection while in the remaining simulation duration of around 220CA base mesh of 2 mm gives a sufficient *** has been found that maximum heat release takes place in Phase-III,the mixing-controlled phase,of the combustion *** than 98%combustion efficiency has been achieved in all the *** 99%of the total heat release and emissions production takes place within 60CA after top dead center(AT

关键词： Phases of combustion Heat release rate(HRR) Integrated heat release rate(IHRR) Emissions Performance parameters

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Computational Algorithms for the Analysis of Cancer Virotherapy Model

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Computers, Materials & Continua 2022年第5期71卷 3621-3634页

作者： ali raza Dumitru Baleanu Muhammad Rafiq syed Zaheer Abbas Abubakar Siddique Umer Javed Mehvish Naz Arooj Fatima Tayyba Munawar Hira Batool Zaighum Nazir Department of Mathematics Govt.Maulana Zafar Ali Khan Graduate College Wazirabad52000Punjab Higher Education Department(PHED)Lahore54000Pakistan Department of Mathematics University of SialkotSialkot51310Pakistan Department of Mathematics Cankaya UniversityBalgatAnkara06530Turkey Department of Medical Research China Medical UniversityTaichung40402Taiwan Department of Mathematics Faculty of SciencesUniversity of Central PunjabLahore54500Pakistan Department of Mathematics National College of Business Administration and EconomicsLahore54660Pakistan Department of Mathematics COMSATS University IslamabadWah CampusQuaid AvenueWah Cantonment47040Pakistan Department of Electrical and Computer Engineering COMSATS University IslamabadWah CampusQuaid AvenueWah Cantonment47040Pakistan

Cancer is a common term for many diseases that can affect any part of the *** 2020,ten million people will die due to cancer.A worldwide leading cause of death is cancer by the World Health Organization(WHO)*** of cancer cells,viral therapy,and immune response are identified in this *** and computational modeling is an effective tool to predict the dynamics of cancer *** cell population is categorized into three parts like uninfected cells(x),infected cells(y),virus-free cells(v),and immune cells(z).The modeling of cancerlike diseases is based on the law of mass action(the rate of change of reacting substances is directly proportional to the product of interacting substances).Positivity,boundedness,equilibria,threshold analysis,are part of deterministic *** on,a numerical analysis is designed by using the standard and non-standard finite difference *** non-standard finite difference method is developed to study the long-term behavior of the cancer *** its efficiency,a comparison of the methods is investigated.

关键词： Cancer disease epidemic model algorithms stability analysis

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Graphene Nanosheets Decorated with Copper Oxide Nanoparticles for the Photodegradation of Methylene Blue

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Chemical Research in Chinese Universities 2022年第6期38卷 1518-1525页

作者： Samavia RAFIQ Zulfiqar ali raza Muhammad ASLAM Muhammad Junaid BAKHTIYAR Department of Applied Sciences National Textile UniversityFaisalabad37610Pakistan

Textile industries extensively use colorants,such as methylene blue,and if disposed off untreated,they contaminate the effluent streams,causing a severe impact on the environment and aquatic *** degradation has been found as an inevitable approach to treat ***,we decorated the copper oxide nanoparticles on graphene nanosheets during the reflux *** resultant copper oxide/graphene nanocomposites were analyzed for structural and functional *** was observed that on increasing the copper oxide contents,the z-average size of the resultant nanocomposites *** X-ray diffraction analysis demonstrated the crystalline nature of the *** surface morphology of the copper oxide nanoparticles appeared to be spherical and that of the copper oxide/graphene composite somehow *** infrared analysis indicated successful intercalation of precursors in the *** bandgap of copper oxide/graphene nanocomposites varied in the range of 1.03—1.30 eV,which indicated their effective photocatalytic *** results demonstrated that after 120 min of exposure,the methylene blue removal efficiency reached 94.0%,92.2%,and 89.4%(mass fraction)on the copper oxide/graphene nanocomposite at copper oxide nanoparticles to graphene nanosheets ratios of 1:1,1.5:1,and 2:1(mass ratio),*** photodegradation performance of the prepared nano-catalyst was found satisfactory even after five cycles.

关键词： Copper oxide Graphene nanosheet Methylene blue Photocatalysis

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Morphological Variations,Distribution and Population Estimation of Indian Spiny Tailed Liza rd(Uromastyx hardwickii Gray,1827)from District Bahawalnagar,Punjab,Pakistan

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Asian Herpetological Research 2020年第3期11卷 257-262页

作者： Waqas ali Arshad JAVID Saddam HUSSAIN ali HUSSAIN syed Mohsin BUKHARI Department of Wildlife and Ecology University of Veterinary and Animal SciencesLahorePakistan

This study was conducted in selected sites of District Bahawalnagar namely,Shaheed Chowk,Chak40/F,Chak 163/7 R and Fareedkot Tiba between March 2019 and August *** techniques included recording of burrows,flooding,burrow exaction,noose traps and pit fall traps were used to capture Uromast yx *** this survey150 individuals were captured from study area for morphological measurement and population *** average snout to vent length(SVL)of male,female and juveniles were(172.50±19.71)mm,(155.50±18.72)mm and(86.25±11.72)mm *** average weight of male,female and juvenile was(93.06±8.56)g,(88.16±7.95)g and(40.16±4.30)g *** relative abundance(Pi)of males,females and juveniles were 0.53,0.33 and *** spiny tailed lizard(***)has been listed in the IUCN Red list and *** threats to the species in the study area are increase in urbanization,habitat fragmentation,illegal hunting for meat and *** this regard strict implementation of the Wildlife act is needed to protect the wildlife of ***,comprehensive surveys are required in throughout Punjab to declare conservation status of ***.

关键词： habitat morphological characters population Uromastyx hardwickii

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