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Motility index measured by magnetic resonance enterography is associated with sex and mural thickness

World Journal of Gastroenterology 2020年第36期26卷 5484-5497页

作者： sven mansson Olle Ekberg Bodil Ohlsson Medical Radiation Physics Department of Translational MedicineLund UniversitySkåne University Hospital MalmöMalmö20502Sweden Department of Translational Medicine Diagnostic RadiologyLund UniversitySkåne University HospitalMalmö20502Sweden Department of Internal Medicine Skåne University HospitalLund UniversityMalmöS-20502Sweden

BACKGROUND Recently,a technique has been developed to use magnetic resonance enterography(MRE)for the evaluation of small bowel *** hypothesis was that assessment of the motility index(MI)should reflect differences in motility between clinical *** To aim of the present observational,cross-sectional study was to evaluate the use of the MI in daily clinical *** All consecutive patients aged 18-70 years who were referred for MRE at the Department of Radiology during a 2-year period were asked to *** volunteers were included as *** was prepared and conducted in accordance with clinical *** the day of examination,all the participants had to complete the visual analog scale for irritable bowel syndrome(IBS)and IBS-symptom severity *** of MI were calculated from dynamic MR *** was used to evaluate differences in MI between groups,classified as healthy,Crohn’s disease,ulcerative colitis,IBS,other assorted disorders and *** and linear regression were applied to the MI *** medical records were scrutinized for medical *** In all,224 examinations were included(inclusion prevalence 76.3%),with 22 controls and 202 *** was a significant difference in the MI of the jejunum(P=0.021)and terminal ileum(P=0.007)between the different *** MI was inversely associated with the mural thickness of the terminal ileum in men(P<0.001)and women(P=0.063)after adjustments,and tended to be lower in men than in women(P=0.056).Subjectively observed reduction of motility on MRI was accomplished by reduced MI of terminal ileum in men(P<0.001)and women(P=0.030).In women,diarrhea was inversely associated with the MI of the jejunum(P=0.029),and constipation was positively associated with the MI of the terminal ileum(P=0.039).CONCLUSION Although MIs differ across diseases,a lower MI of the terminal ileum is mainly associated with male sex and an increased mural thickness.S

关键词： Dysmotility Gastrointestinal symptoms Magnetic resonance enterography Motility index Mural thickness Small bowel

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Impact of Field Strength and Respiratory Motion Control on Diffusion-Weighted MR Imaging of the Liver

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Open Journal of Medical Imaging 2013年第1期3卷 31-39页

作者： Johanna Berg sven mansson Jonas svensson Olle Ekberg Markus F.Müller Skane University Hospital Department of Clinical SciencesLund UniversityMalmoSweden Medical Radiology Lund UniversityMalmoSweden Medical Radiation Physics Lund UniversityMalmoSweden

Purpose: To evaluate the impact of field strength and respiratory motion control on diffusion-weighted MR imaging (DWI) of the liver at 1.5 and 3 T. Material and Methods: Three DWI sequences using seven b-values from 20 - 400 s/mm2 were designed with identical parameters but with different handling of respiratory motion [respiratory triggered (RT), free breathing (FB), breath hold (BH)] on 3 T and 1.5 T. Thirteen volunteers were examined at a 3 T and six of them also at a 1.5 T magnet. DW images were analyzed quantitatively and qualitatively. Regions of interest were placed in cranial, middle and caudal parts of the right liver lobe (RLL) and ADC and SNR were calculated. Results: ADC in RLL tended to be lower at 3 T MRI. Least inter-subject ADC variability was found with RT in the middle RLL at 3 T. Highest ADCs were found caudally in the RLL. Significant differences in ADC between middle and caudal RLL were calculated in FB and RT at 3 T and FB and BH at 1.5 T, respectively. No significant difference in SNR was found between 3 T and 1.5 T. There were significantly more artifacts in the left liver lobe (LLL) compared to the RLL in all sequences and in the LLL at 3 T compared to 1.5 T. Conclusion: Our study suggests that longitudinal hepatic ADC measurements should be performed using equivalent field strength, b-values, and acquisition technique, given influence of these factors on ADC measurements.

关键词： Magnetic Resonance Imaging Diffusion Echo-Planar Imaging 3 T Liver Respiratory Motion

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