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State-of-the-art review of soft computing applications in underground excavations

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Geoscience Frontiers 2020年第4期11卷 1095-1106页

作者： Wengang Zhang Runhong Zhang Chongzhi Wu Anthony Teck Chee Goh suzanne Lacasse Zhongqiang Liu Hanlong Liu Key Laboratory of New Technology for Construction of Cities in Mountain Area Chongqing UniversityMinistry of EducationChongqing 400045China National Joint Engineering Research Center of Geohazards Prevention in the Reservoir Areas Chongqing UniversityChongqing 400045China School of Civil Engineering Chongqing UniversityChongqing 400045China School of Civil and Environmental Engineering Nanyang Technological University639798Singapore Department of Natural Hazards Norwegian Geotechnical Institute0806 OsloNorway

Soft computing techniques are becoming even more popular and particularly amenable to model the complex behaviors of most geotechnical engineering systems since they have demonstrated superior predictive capacity,compared to the traditional *** paper presents an overview of some soft computing techniques as well as their applications in underground excavations.A case study is adopted to compare the predictive performances of soft computing techniques including eXtreme Gradient Boosting(XGBoost),Multivariate Adaptive Regression Splines(MARS),Artificial Neural Networks(ANN),and Support Vector Machine(SVM) in estimating the maximum lateral wall deflection induced by braced *** study also discusses the merits and the limitations of some soft computing techniques,compared with the conventional approaches available.

关键词： Soft computing method(SCM) Underground excavations Wall deformation Predictive capacity

Plasticity of spermatogonial stem cells

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Asian Journal of Andrology 2015年第3期17卷 355-359页

作者： Paul S Cooke Liz Simon Manjunatha K Nanjappa Theresa I Medrano suzanne E Berry Department of Physiological Sciences College of Veterinary Medicine University of Florida Gainesville FL 32608 USA Department of Physiology Louisiana State University Health Sciences Center New Orleans LA 70112 USA Department of Comparative Biosciences College of Veterinary Medicine University of Illinois at Urbana-Champaign Urbana IL 61802 USA

There have been significant breakthroughs over the past decade in the development and use of pluripotent stem cells as a potential source of cells for applications in regenerative medicine. It is likely that this methodology will begin to play an important role in human clinical medicine in the years to come. This review describes the plasticity of one type of pluripotent cell, spermatogonial stem cells （SSCs）, and their potential therapeutic applications in regenerative medicine and male infertility. Normally, SSCs give rise to sperm when in the testis. However, both human and murine SSCs can give rise to cells with embryonic stem （ES） cell-like characteristics that can be directed to differentiate into tissues of all three embryonic germ layers when placed in an appropriate inductive microenvironment, which is in contrast to other postnatal stem cells. Previous studies have reported that SSCs expressed an intermediate pluripotent phenotype before differentiating into a specific cell type and that extended culture was necessary for this to occur. However, recent studies from our group using a tissue recombination model demonstrated that SSCs differentiated rapidly into another tissue, in this case, prostatic epithelium, without expression of pluripotent ES cell markers before differentiation. These results suggest that SSCs are capable of directly differentiating into other cell types without going through an intermediate ES cell-like stage. Because SSCs do not require reprogramming to achieve a pluripotent state, they are an attractive source of pluripotent cells for use in regenerative medicine.

关键词： pluripotency regenerative medicine spermatogenesis testis

Developmental environment contributes to rapid trait shifts among newly colonized subterranean habitats

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Zoological Research 2023年第4期44卷 808-820页

作者： Nathan E.Swanson Andrew G.Gluesenkamp Alexandra E.Donny suzanne E.McGaugh Department of Fisheries Wildlife and Conservation BiologyUniversity of MinnesotaSaint PaulMN 55108USA Department of Ecology and Evolutionary Biology University of California IrvineIrvineCA 92697-2525USA Center for Conservation and Research San Antonio ZooSan AntonioTexas 78212USA Ecology Evolutionand BehaviorUniversity of MinnesotaSaint PaulMN 55108USA Department of Biology Stanford UniversityStanfordCA 94305USA

Recent colonization of extreme environments provides unique opportunities to study the early steps of adaptation and the potential for rapid convergent ***,phenotypic shifts during recent colonization may also be due to plasticity in response to changes in the rearing ***,we analyzed a suite of morphological and behavioral traits in paired surface,subterranean,and facultatively subterranean Mexican tetras(Astyanax mexicanus)from recent introductions in two separate watersheds outside of their native *** found a variety of phenotypic and behavioral shifts between subterranean and surface populations that are similar to those observed in relatively ancient populations in *** this rapid morphological divergence,we found that most of these trait differences were due to plasticity in response to rearing *** most trait assays in common-garden,lab-raised fish indicated that phenotypic shifts in wild fish were the result of plasticity,we also found evidence of genetic control in several traits present in subterranean ***,wall-following behavior,an important subterranean foraging behavior,was greater in lab-born subterranean fish than in lab-born surface fish,suggesting rapid divergence of this trait between subterranean and surface ***,this study sheds light on the early steps of subterranean evolution,identifies potential rapid behavioral evolution,and suggests that plasticity in traits involving exploratory behavior may facilitate subterranean colonization.

关键词： Plasticity Adaptation Subterranean Cavefish Evolution Common garden

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Jacob's room

Modelling of shallow landslides with machine learning algorithms

作者： Virginia Woolf edited by suzanne Raitt.

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Geoscience Frontiers 2021年第1期12卷 385-393页

作者： Zhongqiang Liu Graham Gilbert Jose Mauricio Cepeda Asgeir Olaf Kydland Lysdahl Luca Piciullo Heidi Hefre suzanne Lacasse Norwegian Geotechnical Institute(NGI) Sognsveien 720855OsloNorway

This paper introduces three machine learning(ML)algorithms,the‘ensemble'Random Forest(RF),the‘ensemble'Gradient Boosted Regression Tree(GBRT)and the Multi Layer Perceptron neural network(MLP)and applies them to the spatial modelling of shallow landslides near Kvam in *** the development of the ML models,a total of 11 significant landslide controlling factors were *** controlling factors relate to the geomorphology,geology,geo-environment and anthropogenic effects:slope angle,aspect,plan curvature,profile curvature,flow accumulation,flow direction,distance to rivers,water content,saturation,rainfall and distance to *** is observed that slope angle was the most significant controlling factor in the ML *** performance of the three ML models was evaluated quantitatively based on the Receiver Operating Characteristic(ROC)*** results show that the‘ensemble'GBRT machine learning model yielded the most promising results for the spatial prediction of shallow landslides,with a 95%probability of landslide detection and 87%prediction efficiency.

关键词： Shallow landslide Spatial modelling Machine learning GIS

Missed opportunities for hepatitis C treatment at a tertiary care hospital in South Australia

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World Journal of Hepatology 2022年第8期14卷 1576-1583页

作者： Sreecanth Sibhi Raja suzanne Edwards Jeffrey Stewart Dep Huynh Department of Gastroenterology The Queen Elizabeth HospitalWoodville 5011South AustraliaAustralia Department of Statistician School of Public HealthUniversity of AdelaideAdelaide 5000South AustraliaAustralia

BACKGROUND Hepatitis C is a global epidemic and an estimated 230000 Australians were living with chronic hepatitis C in *** effective public health policy and state commitment,Australia has utilised the advent of direct acting antiviral(DAA)therapy to transform the therapeutic landscape for hepatitis C virus(HCV).However,treatment rates are falling and novel public health approaches are required to maintain momentum for HCV *** discourse in cascades of care have focused on expanding testing capabilities but less attention has been given to linking previously diagnosed patients back to *** simple and focused study rests on the premise that hospital admissions are an excellent opportunity to identify and refer previously diagnosed patients for HCV *** To assess whether inpatients with HCV are appropriately referred on for *** We conducted a retrospective single centre cohort study that examined all patients with HCV presenting to The Queen Elizabeth Hospital(QEH)inpatient service between January 1 and December 31,*** is a tertiary care hospital in South *** main inclusion criteria were patients with active HCV infection who were eligible for DAA *** study cohort was identified using a comprehensive list of diagnosis based on international classification of diseases-10 AM codes for chronic viral *** were excluded from the analysis if they had previously received DAA therapy or spontaneously cleared *** presenting with decompensated liver cirrhosis or other systemic medical conditions conferring poor short-term prognosis were also excluded from the *** primary outcome of our study was referral of patients for HCV *** outcomes included assessment of factors predicting treatment *** There were 309 inpatients identified with hepatitis C as a principal or additional diagnosis between January 1 and December 31,*** these patients,

关键词： Hepatitis C Viral hepatitis Treatment cascade Hepatology Public health Missed opportunities

As clear as mud： Turbidity induces behavioral changes in the African cichlid Pseudocrenilabrus multicolor

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Current Zoology 2012年第1期58卷 146-157页

作者： Gray, suzanne M. McDonnell, Laura H. Cinquemani, Fabio G. Chapman, Lauren J. Department of Biology McGill University 1205 Dr. Penfield Ave Montreal QC Canada H3A 1B1 Wildlife Conservation Society 2300 Southern Boulevard Bronx NY 10460 USA

Aquatic biodiversity is being lost at an unprecedented rate. One factor driving this loss is increased turbidity, an en- vironmental stressor that can impose behavioral, morphological, and/or physiological costs on fishes. Here we describe the be- havioral response of a widespread African cichlid, Pseudocrenilabrus multicolor victoriae, to turbidity. We used a split-brood rearing design to test if F1 offspring reared in turbid water, originating from river （turbid） and swamp （clear） populations, behave differently than full-sibs reared in clear water. We examined two facets of behavior：（1） behaviors of fish in full sib groups, in- eluding activity level and social dynamics collected during the rearing period; and （2） male aggressive behavior directed at poten- tial male competitors after fish had reached maturity; this was done in an experimental set-up independent of the rearing aquaria. Regardless of population of origin, fish reared in turbid water were marginally less active and performed fewer social behaviors than those reared in clear water. On the other hand, when tested against a competitor in turbid water, males performed more ag- gressive behaviors, regardless of population of origin or rearing environment, Our results suggest a plastic behavioral response to turbidity that may allow P. multicolor to persist over a range of turbidity levels in nature by decreasing activity and general social behaviors and intensifying reproductive behaviors to ensure reproductive success [Current Zoology 58 （1）： 146-157, 2012].

关键词： Cichlidae Behavioral plasticity Environmental stressor Male-male competition

A guide for selecting the appropriate plot design to measure ungulate browsing

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Forest Ecosystems 2023年第6期10卷 732-742页

作者： suzanne T.S.van Beeck Calkoen Jerome Milch Andrea D.Kupferschmid Christian Fiderer Marco Heurich Department of Visitor Management and National Park Monitoring Bavarian Forest National ParkFreyunger Straße 294481 GrafenauGermany Wildlife Ecology and Management Albert-Ludwigs-University of FreiburgTennenbacher Str.479106 FreiburgGermany Swiss Federal Research Institute WSL Zürcherstrasse 1118903 BirmensdorfSwitzerland Faculty of Applied Ecology Agricultural Sciences and BiotechnologyInstitute for Forest and Wildlife ManagementCampus EvenstadKoppangNorway

Ungulate browsing often impairs tree regeneration,thus preventing the achievement of economic or conservation *** ungulate management would thus benefit from a practical decision tool that facilitates method selection from a wide range of monitoring methods and indicators currently *** this study,we first provide an overview of the different browsing-impact monitoring methods and indicators currently *** then present a newly developed decision matrix for method evaluation that can assist forest stakeholders in choosing the browsing-impact monitoring method best suited to their needs,based on the selected *** first step involved two separate literature reviews to create an overview of the currently applied methods and to select the indicators best suited for measuring browsing *** types of indicator groups with their respective parameters were considered important for method evaluation:browsing indicators(*** density,browsing incidents),performance indicators(***,expertise)and data quality indicators(*** to measurement errors).Subsequently,all parameters defined within each indicator group were categorised and a grade was assigned to each *** create the final method-indicator matrix,each browsing-impact monitoring method received a grade for each parameter within all indicator groups,reflecting the specific advantages and disadvantages of implementing the respective parameter within a specific *** utility of the matrix in selecting the most suitable monitoring method was then demonstrated using the example of Germany's national *** on the weights added to the method-indicator matrix,as defined by national park representatives,and considering local requirements the nearest-tree method was favoured over the other two *** newly developed matrix provides a more scientific objectification of ungulate browsing-impact measures and can be easily used by forest man

关键词： Ungulate Browsing impact Monitoring Indicator Decision matrix Forest management

Development of tropoelastin-functionalized anisotropic PCL scaffolds for musculoskeletal tissue engineering

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Regenerative Biomaterials 2023年第1期10卷 64-72页

作者： Miao Zhang Ziyu Wang Anyu Zhang Linyang Liu suzanne M.Mithieux Marcela M.M.Bilek Anthony S.Weiss Charles Perkins Centre The University of SydneySydneyNSW 2006Australia School of Life and Environmental Sciences The University of SydneySydneyNSW 2006Australia Applied and Plasma Physics Laboratory School of PhysicsThe University of SydneySydneyNSW 2006Australia School of Biomedical Engineering The University of SydneySydneyNSW 2006Australia Sydney Nano Institute The University of SydneySydneyNSW 2006Australia

The highly organized extracellular matrix(ECM)of musculoskeletal tissues,encompassing tendons,ligaments and muscles,is structurally anisotropic,hierarchical and *** features collectively contribute to their unique *** studies have investigated the effect of tissue-engineered scaffold anisotropy on cell morphology and organization for musculoskeletal tissue repair and regeneration,but the hierarchical arrangement of ECM and compartmentalization are not typically ***,we present a method for multi-compartmental scaffold design that allows for physical mimicry of the spatial architecture of musculoskeletal tissue in regenerative *** design is based on an ECM-inspired macromolecule ***(PCL)scaffolds were fabricated with aligned fibers by electrospinning and mechanical stretching,and then surface-functionalized with the cell-supporting ECM protein molecule,tropoelastin(TE).TE was attached using two alternative methods that allowed for either physisorption or covalent attachment,where the latter was achieved by plasma ion immersion implantation(PIII).Aligned fibers stimulated cell elongation and improved cell alignment,in contrast to randomly oriented *** coatings bound by physisorption or covalently following 200 s PIII treatment promoted fibroblast *** represents the first cytocompatibility assessment of novel PIII-treated TE-coated PCL *** demonstrate their versatility,these 2D anisotropic PCL scaffolds were assembled into 3D hierarchical constructs with an internally compartmentalized structure to mimic the structure of musculoskeletal tissue.

关键词： tropoelastin PCL musculoskeletal tissue engineering plasma immersion ion implantation electrospinning anisotropy hierarchical