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Bioactivity of compounds isolated from the leaves of the Lantana camara Linn plant

Journal of Chinese Pharmaceutical Sciences 2019年第5期28卷 360-368页

作者： suryati Elida Mardiah Mai Efdi Kartika MZ Yuni Mala Sari Department of Chemistry Faculty of Mathematics and Sciences Andalas University

Two compounds with different bioactivities were isolated from the leaves of the Lantana camara Linn *** 1 was triterpenoid(Lantadene B)(22β-dimethylacroyloxy-3-oxoolean-12-en-28-oic-acid,C_(35)H_(52)O_5),which was isolated from n-hexane fraction and obtained as white solid(amorphous).Compound 2 was glycoside flavonoid(5-hydroxy-6,4′-dimethoxy flavon-7-O-glucopyranose,C_(23)H_(24)O_(11)),which was isolated from ethyl acetate and obtained as pale yellow solid(amorphous).Extraction was performed with maceration method using methanol ***,fractionation was carried out using n-hexane and ethyl acetate *** and purification of both fractions were conducted using chromatography *** structure of the isolated compounds was determined through spectral analyses of ultraviolet(UV),infrared(IR),and nuclear magnetic resonance(~1H NMR and ^(13)C NMR),distortionless enhancement by polarization transfer(DEPT),heteronuclear multiple bond connectivity(HMBC),heteronuclear single quantum correlation(HSQC),and H-H COSY(~1H-~1H homonuclear correlated spectroscopy).The cytotoxic activity of compound 1 was tested against MCF-7 breast cancer cells in vitro using MTT assay(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide),showing very strong cytotoxic activity in inhibiting the growth of MCF-7 breast cancer cells,and the IC_(50) value was 1.1336μ*** antioxidant activity of compound 2 was tested using DPPHassay(1,1-diphenyl-2-picrylhydrazyl),showing strong activity in inhibiting free radicals,and its IC_(50) value was 71.03 mg/L.

关键词： Lantana camara Linn Lantadene B Glycosides flavonoid MCF-7 breast cell cancer Cytotoxic Antioxidant activity

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Perceptions of People on Police Efficiency and Crime Prevention in Urban Areas in Malaysia

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Economics World 2016年第5期4卷 243-248页

作者： suryati Ishak Universiti Putra Malaysia Selangor Malaysia

Crime cases from snatch thefts to murders, are becoming increasingly common in Malaysia according to the database of the Royal Malaysian Police （RMP）, the current overall Crime Index in Malaysia was 147,062 for 2013 compared with 65,237 in 1977. The database also revealed that the number of property crimes reported in this country has always exceeded the number of violent crimes. Although in 2013, crimes related to property are higher （117,687） than violent crime （29,375）, the gradual increase in the latter does worry Malaysians. Likewise, Malaysian Government had implemented a ＂safe community＂ concept, inspired by the Malaysian Crime Prevention Foundation （MCPF）, a non-government organization, as they were concerned that the threat of violent crime and non-violent crime would eventually reduce the quality of life for many individuals. The concept is very important to the public as it is perceived as improved safety for the public with less crime. This study analyzes the public safety through their perceptions on the effectiveness of the policeman and suggesting few prevention actions against crime. The data were collected using a self-administered survey questionnaire. Specifically, this study focuses on the more developed states in this country. From the cross tabulation analysis, the majority of respondents agreed that the police are effective in controlling crime. Approximately, 72.1% of respondents felt that the police are efficient in controlling crime.

关键词： crime crime prevention perceptions of people police efficiency public safety quality of life

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Methanolysis of Mixed Crop Oils (<i>Hevea brasiliensis</i>and <i>Jatropha curcas</i>L.) into Biodiesel: Kinetics Study

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Smart Grid and Renewable Energy 2017年第12期8卷 440-448页

作者： Azhari M. Syam Zulfikar suryati Leni Maulinda Fikri Haspita Department of Chemical Engineering University of Malikussaleh Lhokseumawe Indonesia Department of Mechanical Engineering University of Malikussaleh Lhokseumawe Indonesia

In this study, the methanolysis of mixed crop oils (Hevea brasiliensis and Jatropha curcas L.) was investigated. Due to the oils contain high impurities, a particular pre-treatment of which was carried out. For alkali-catalyzed methanolysis, few parameters (such as: molar ratio, catalyst percentage, and reaction time) were studied. The results showed that the methanolysis optimum conditions were 5.5 of molar ratio, 0.9% w/w of catalyst, and 60 minutes of reaction time with the highest yield of 98.9%. The kinetics study indicated that first order reaction mechanism with reaction rate constant and activation energy were 1.5 × 10-2 minute-1 and 23.93 KJ?mol-1 respectively. As fuel, the physicochemical properties of biodiesel met the standard values required by ASTM D6751.

关键词： Biodiesel Methanolysis Hevea brasiliensis Jatropha curcass L.

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