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Effect of blast inside tunnel on surrounding soil mass,tunnel lining,and superstructure for varying shapes of tunnels

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Underground Space 2021年第6期6卷 619-635页

作者： M.D.goel Shivani Verma Jagriti Mandal Sandeep Panchal Department of Applied Mechanics Visvesvaraya National Institute of Technology(VNIT)Nagpur 440010MaharashtraIndia Department of Mining Engineering Visvesvaraya National Institute of Technology(VNIT)Nagpur 440010MaharashtraIndia

In this study,a finite element(FE)analysis of shallow tunnels exposed to a blast inside the tunnel,with soil as surrounding medium and a structure at ground level,was *** ConWep program,developed by the US Army,was used to simulate blast loading using ABAQUS/Explicit■.Drucker-Prager(D-P)plasticity model,concrete damage plasticity(CDP),and Johnson-Cook(J-C)plasticity models were used to define the behavior of the soil,concrete,and reinforcement,*** analysis was carried out to compare the damages to the superstructure with variation in the cross-sectional shapes of the tunnel under internal blast *** tunnel shapes(circular,rectangular,and horseshoe cross-sections)were considered in the FE *** explosive of 100 kg TNT was located at the center of the cross-section of the *** response of the tunnel in terms of displacement and stress at critical locations was *** results showed that changes in the cross-section of the tunnel affect the stability of the tunnel,even when keeping all other factors *** was observed that the intensity of the stresses was the highest for a rectangular tunnel and lowest for a circular ***,it was also determined that the tunnel with a rectangular cross-section experienced the maximum displacement in the reinforced concrete(RC)lining compared with the horseshoe and circular *** displacement measured at critical structural members of the superstructure was found to be the highest for the tunnel with a rectangular cross-section and lowest for the tunnel with a circular cross-section.

关键词： Blast loading Numerical simulation ConWep Framed superstructure FE analysis ABAQUS/Explicit■

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Vivax malaria:a rare cause of thalamic bleed

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Asian Pacific Journal of Tropical Medicine 2012年第8期5卷 665-666页

作者： Jaydeep Sarkar Biku Naik Atul Gawande Atul goel Department of Internal Medicine Lady Hardinge Medical CollegePGIMERand Dr.RML HospitalNew DelhiIndia

Most common cause of thalamic bleed is hypertension;other causes are arteriovenous malformation,aneurysm,bleeding thathesis,drugs,amyloid angiopathy,tumor *** present a case of Plasmodium vivax(***) malaria with unusual site of bleeding *** thalamus of *** the best of our knowledge,this is the first reported case of thalamic bleed caused by vivax malaria in absence of severe thrombocytopenia/disseminated intravascular coagulation (DIC).

关键词： Malaria Plasmodium vivax Bleed Thalamus Rapid malaria test

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Lingual hematoma causing upper airway obstruction:an unusual manifestation of dengue fever

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Asian Pacific Journal of Tropical Medicine 2011年第5期4卷 412-413页

作者： Jaydeep Sarkar Charu Mohan DN Misra Atul goel Department of Internal Medicine Lady Hardinge Medical CollegePGIMERDrRML Hospital

The spectrum of dengue infection varies from dengue fever to more severe forms such as dengue hemorrhagic fever(DHF) and dengue shock syndrome(DSS).In DHF bleeding may be overt (external) or *** time bleeding can occur at unusual *** report one such case of DHF in which bleeding occurred within the tongue manifesting as an intra-lingual hematoma, causing significant upper airway obstruction.

关键词： Hematoma Tongue Dengue Platelet

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Impacts of Bioinoculants Pseudomonas jesenii MP1 and Rhodococcus qingshengii S10107 on Chickpea (Cicer arietinum L.) Yield and Soil Nitrogen Status

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Pedosphere 2019年第3期29卷 388-399页

作者： Divya JOSHI Ramesh CHANDRA Deep Chandra SUYAL Saurabh KUMAR Reeta goel Department of Microbiology College of Basic Sciences and Humanities Govind Ballabh Pant University of Agriculture and Technology Pantnag ar-263145 Uttarakhand (India) Department of Soil Science College of Agriculture Govind Ballabh Pant University of Agriculture and Technology Pantnagar- 263145 Uttarakhand (India)

Cold-adapted bioinoculants are considered as harbingers of sustainable hill agriculture. Therefore, two previously characterized psychrotolerant diazotrophs, Pseudomonas jesenii MP1 and Rhodococcus qingshengii S10107, were evaluated for their plant growthpromoting potential for chickpea (Cicer arietinum L.) grown under natural field conditions. Comparative analysis of agronomical and biochemical crop parameters revealed the irrelevance of chemical fertilizers for chickpea production;the diazotrophs alone were sufficient to fulfil the crop's nutritional requirement. However, the integrated use of bacterial strains in combination with urea at 20 kg N ha^-1 as urea was being recommended for higher crop yield and better soil nitrogen status. Quantitative polymerase chain reaction (qPCR) and denaturing gradient gel electrophoresis (DGGE)-based soil bacterial dynamics unveiled the persistence of both diazotrophs until the end of the crop maturation period without affecting the native micro-flora. Therefore, these bioinoculants can be explored as natural nitrogen resource, and an additional incentive in their bio-formulation will be a step towards agricultural sustainability.

关键词： agricultural sustainability denaturing gradient gel electrophoresis (DGGE) hill agriculture psychrotolerance N fertilizer N fixation N uptake quantitative polymerase chain reaction (qPCR)

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Characterization of municipal solid waste based on seasonal variations,source and socio-economic aspects

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Waste Disposal and Sustainable Energy 2021年第4期3卷 275-288页

作者： Venkata Ravi Sankar Cheela Sudha goel Michele John Brajesh Dubey Environmental Engineering and Management Department of Civil EngineeringIndian Institute of Technology KharagpurKharagpurWest Bengal 721302India Sustainable Engineering Group Curtin UniversityPerthWA 6102Australia

Municipal solid waste(MSW)generation and characterization are the basic inputs for waste handling and treatment systems *** present research,we performed waste characterization investigations in Visakhapatnam(India),using a waste characterization methodology by integrating two standard sampling and characterization *** characterization methodology was designed by combining seasonal variations,source,and socio-economic ***-based sampling was performed at household(s),dumpster(s),transfer station,and ***-economic-based sampling was performed based on the zone classification of the *** sampling campaigns were conducted to identify the waste composition based on seasonal *** aimed to perform stratified characterization of waste and assess chemical characteristics of the mixed waste fractions to evaluate waste-to-energy *** indicate that the amount of MSW generated in the city is 1250±100 tons/day,with a generation rate of 0.65 kg/capita/*** on source stratification,organic matter(45.5%±6.5%)is a major component followed by inert *** paper,plastic,and textile components amount to 25%of overall *** seasonal studies,organic matter was higher in pre-monsoon(42%)compared to winter(39%).The moisture content of MSW varied between 30%and 35%and volatile solids between 39%and 43%.The calorific value was determined to be between 5680-7110 kJ/*** the limitations and potential errors associated with sampling and waste *** and thermal conversion treatment alternatives for processing,treatment,and handling were *** findings of this research would assist regulatory bodies and city councils to formulate policy directives on waste sampling,characterization,segregation,education,and awareness campaigns.

关键词： Municipal solid waste Waste characterization Source segregation Socio-economic Seasonal variation Waste-to-energy

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General synthesis of silica-based yolk/shell hybrid nanomaterials and in vivo tumor vasculature targeting

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Nano Research 2018年第9期11卷 4890-4904页

作者： Feng Chen Shreya goel Sixiang Shi Todd E. Barnhart Xiaoli Lan Weibo Cai Department of Radiology University of Wisconsin-Madison W153705 USA Materials Science Program University of Wisconsin-Madison W153705 USA Department of Medical Physics University of Wisconsin-Madison WI 53705 USA Department of Nuclear Medicine Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China University of Wisconsin Carbone Cancer Center Madison W153705 USA

Multifunctional yolk/shell-structured hybrid nanomaterials have attracted increasing interest as theranostic nanoplatforms for cancer imaging and therapy. However, because of the lack of suitable surface engineering and tumor targeting strategies, previous research has focused mainly on nanostructure design and synthesis with few successful examples showing active tumor targeting after systemic administration. In this study, we report the general synthetic strategy of chelator-free zirconium-89 （89Zr）-radiolabeled, TRC105 antibody-conjugated, silica-based yolk/sheU hybrid nanopartides for in vivo tumor vasculature targeting. Three types of inorganic nanoparticles with varying morphologies and sizes were selected as the internal cores, which were encapsulated into single hollow mesoporous silica nanosheUs to form the yolk/sheU-structured hybrid nanopartides. As a proof-of-concept, we demonstrated successful surface functionalization of the nanoparticles with polyethylene glycol, TRC105 antibody （specific for CD105/endoglin）, and ~Zr （a positron-emitting radioisotope）, and enhanced in vivo tumor vasculature-targeted positron emission tomography imaging in 4T1 murine breast tumor-bearing mice. This strategy could be applied to the synthesis of other types of yolk/shell theranostic nanoparticles for tumor- targeted imaging and drug delivery.

关键词： yolk/shelLintrinsic radiolabeling vasculature targeting positron emission tomography zirconium-89

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Atomic-Scale Friction Studies on Single-Crystal Gallium Arsenide Using Atomic Force Microscope and Molecular Dynamics Simulation

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Nanomanufacturing and Metrology 2022年第1期5卷 39-49页

作者： Pengfei Fan Saurav goel Xichun Luo Hari M.Upadhyaya Centre for Precision Manufacturing DMEMUniversity of StrathclydeGlasgowUK School of Engineering London South Bank University103 Borough RoadLondon SE10AAUK School of Aerospace Transport and ManufacturingCranfield UniversityBedfordshire MK430ALUK Department of Mechanical Engineering Shiv Nadar UniversityGautam Buddh Nagar 201314India

This paper provides a fresh perspective and new insights into nanoscale friction by investigating it through molecular dynamics(MD)simulation and atomic force microscope(AFM)nanoscratch *** work considered gallium arsenide,an importantⅢ-Ⅴdirect bandgap semiconductor material residing in the zincblende structure,as a reference sample material due to its growing usage in 5G communication *** the simulations,the scratch depth was tested as a variable in the fine range of 0.5-3 nm to understand the behavior of material removal and to gain insights into the nanoscale *** force,normal force,and average cutting forces were extracted from the simulation to obtain two scalar quantities,namely,the scratch cutting energy(defined as the work performed to remove a unit volume of material)and the kinetic coefficient of friction(defined as the force ratio).A strong size effect was observed for scratch depths below 2 nm from the MD simulations and about 15 nm from the AFM experiments.A strong quantitative corroboration was obtained between the specific scratch energy determined by the MD simulations and the AFM experiments,and more qualitative corroboration was derived for the pile-up and the kinetic coefficient of *** conclusion suggests that the specific scratch energy is insensitive to the tool geometry and the scratch speed used in this ***,the pile-up and kinetic coefficient of friction are dependent on the geometry of the tool tip.

关键词： AFM nanoscratching Molecular dynamic(MD)simulation Single-crystal gallium arsenide Friction

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Economical evaluation of large-scale photovoltaic systems using Universal Generating Function techniques

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Journal of Modern Power Systems and Clean Energy 2013年第2期1卷 167-176页

作者： Yi DING Weixiang SHEN Gregory LEVITIN Peng WANG Lalit goel Qiuwei WU Department of Electrical Engineering Technical University of DenmarkLyngbyDenmark Faculty of Engineering&Industrial Sciences Swinburne University of TechnologyHawthornVICAustralia Reliability&Equipment Department R&D DivisionThe Israel Electric Corporation Ltd.HaifaIsrael School of EEE Nanyang Technological UniversitySingaporeSingapore

Solar energy plays an important role in the global energy framework for *** with conventional generation systems using fossil fuels,the cost structure of photovoltaic(PV)systems is different:the capital cost is higher while the operation cost is *** of the PV system can also influence the cost for producing ***,planners and regulators require deep insight into the return and cost of a PV project.A reliability based economical assessment of largescale PV systems has been conducted utilizing Universal Generating Function(UGF)*** reliability models of solar panel arrays,PV inverters and energy production units(EPUs)are represented as the corresponding *** expected energy production models for different PV system configurations have also been *** expected unit cost of electricity has been calculated to provide informative metrics for making optimal *** proposed method has been applied to determine the PV system configuration which provides electricity for a water purification process.

关键词： Photovoltaic system Reliability Economical assessment Configuration

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Nanodroplet-mediated catheter-directed sonothrombolysis of retracted blood clots

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Microsystems & Nanoengineering 2021年第1期7卷 77-83页

作者： Leela goel Huaiyu Wu Bohua Zhang Jinwook Kim Paul A.Dayton Zhen Xu Xiaoning Jiang Department of Mechanical&Aerospace Engineering North Carolina State UniversityRaleighNC 27695USA The Joint Department of Biomedical Engineering The University of North Carolina at Chapel Hill and North Carolina State UniversityChapel HillNC 27599USA Department of Biomedical Engineering University of MichiganAnn ArborMI 48109USA

One major challenge in current microbubble(MB)and tissue plasminogen activator(tPA)-mediated sonothrombolysis techniques is effectively treating retracted blood clots,owing to the high density and low porosity of retracted ***(NDs)have the potential to enhance retracted clot lysis owing to their small size and ability to penetrate into retracted clots to enhance drug *** the first time,we demonstrate that a sub-megahertz,forwardviewing intravascular(FVI)transducer can be used for ND-mediated sonothrombolysis,in *** this study,we determined the minimum peak negative pressure to induce cavitation with low-boiling point phase change nanodroplets and clot *** then compared nanodroplet mediated sonothrombolysis to MB and tPA mediate *** clot lysis as a percent mass decrease in retracted clots was 9±8%,9±5%,16±5%,14±9%,17±9%,30±8%,and 40±9%for the control group,tPA alone,tPA+US,MB+US,MB+tPA+US,ND+US,and ND+tPA+US groups,*** retracted blood clots,combined ND-and tPA-mediated sonothrombolysis was able to significantly enhance retracted clot lysis compared with traditional MB and tPA-mediated sonothrombolysis *** nanodroplet with tPA-mediated sonothrombolysis may provide a feasible strategy for safely treating retracted clots.

关键词： thrombolysis directed boiling

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Leptospirosis:a re-emerging infection

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Asian Pacific Journal of Tropical Medicine 2012年第6期5卷 500-502页

作者： Jaydeep Sarkar Aditi Chopra Bhimrai Katageri HansRaj Atul goel Department of Internal Medicine Lady Hardinge Medical College UnitsPGIMERand Dr.RML Hospital

Leptospirosis,long thought to be a disease of sewage workers and found post-flooding is reemerging as a potentially life threatening infectious disease in urban India during monsoon and immediately after due to poor sanitation and ***,it is often ignored and under diagnosed due to a low index of *** present a fatal case of leptospirosis with acute liver failure,respiratory failure and jaundice and encephalopathy.

关键词： Leptospirosis Respiratory failure Jaundice Encephalopathy

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