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Macrophage activation syndrome in children with Kawasaki disease: diagnostic and therapeutic approaches

World Journal of Pediatrics 2020年第6期16卷 566-574页

作者： Seung Beom han soo-Young Lee Department of Pediatrics Daejeon St.Mary's Hospital.College of MedicineThe Catholic University of Korea64 Daeheung-ro.Jung-guDaejeon 34943Republic of Korea Department of Pediatrics.Bucheon St.Mary's Hospital College of MedicineThe Catholic University of Korea327 Sosa-roWonmi-gu.Bucheon 14647Republic of Korea

Background Macrophage activation syndrome(MAS)is a rare,life-threatening complication of Kawasaki disease(KD).Early recognition and treatment of MAS are very important,but sometimes it is difficult to distinguish MAS from a severe form of *** sources A PubMed search was performed in Clinical Queries using the key terms“macrophage activation syndrome or secondary hemophagocytic lymphohistiocytosis(HLH)”and“Kawasaki disease”.Results KD patients with MAS show high intravenous immunoglobulin(IVIG)resistance and coronary *** is also as high as MAS in other *** fever greater than 10 days is highly associated with development of MAS in *** is observed in more than two-thirds of KD patients with *** is often the earliest laboratory finding of *** is highly specific and sensitive for detecting MAS in KD;so,ferritin levels should be checked if there are unexplained clinical exacerbations in KD *** the under-recognition of MAS in KD,it is prudent to consider resistant KD as occult/subclinical *** KD patients with MAS have good outcomes on immune ***,if KD patients fulfill the HLH-2004 diagnostic criteria,they may undergo longer and more intensive treatment than *** The possible existence of MAS should be taken into account when a KD patient shows persistent fever,splenomegaly,thrombocytopenia,hyperferritinemia,or IVIG *** under-diagnosis of MAS in patients with KD is an important issue to be ***,however,there is a possibility of over-treatment of MAS in patients with KD.

关键词： Macrophage activation syndrome Kawasaki disease Children

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Clinical features of strabismus and nystagmus in bilateral congenital cataracts

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International Journal of Ophthalmology(English edition) 2018年第5期11卷 813-817页

作者： sung soo Hwang Wan soo Kim soo Jung Lee Department of Ophthalmology Haeundae Paik Hospital Inje University College of Medicine Busan 48108 Korea Kim Wan soo Eye Clinic Busan 48266 Korea

AIM：To evaluate the prevalence,clinical features,and the factors affecting onset of strabismus and nystagmus in patients with bilateral congenital ***：This study evaluated 116 eyes of 58 patients who underwent lens removal for the treatment of bilateral congenital cataracts between January 1999 and January *** presence and type of strabismus and nystagmus were determined before and after *** of strabismus and final visual acuity were compared in patients with and without *** were divided into three groups（orthotropia/orthotropia,orthotropia/strabismus,and strabismus/strabismus） according to their preoperative and postoperative ocular *** at cataract surgery and associations of nystagmus and primary intraocular lens（IOL） implantation with strabismus were ***：Six patients（10.3%） had strabismus preoperatively and an additional 11（19.0%） developed postoperative *** was more common than esotropia both preoperatively and *** patients（31.0%） had postoperative nystagmus,with sensory nystagmus being the most common *** the 18 patients with nystagmus,10 had strabismus,with exotropia being more common than *** visual acuity was poor in patients with *** at cataract surgery and rate of primary IOL implantation were significantly lower,and postoperative nystagmus was more common,in the orthotropia/strabismus group than in the other two ***：Exotropia and sensory nystagmus are common in patients with bilateral congenital *** at cataract surgery and rate of IOL implantation are lowerand nystagmus more common in patients with postoperative onset of *** is associated with poor visual prognosis.

关键词： bilateral congenital cataracts strabismus nystagmus

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Sensitivity analysis for axis rotation diagrid structural systems according to brace angle changes

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Earthquake Engineering and Engineering Vibration 2017年第4期16卷 783-791页

作者： Jae-Kwang Yang Long-Yang Li sung-soo Park Department of Architectural Engineering Pusan National UniversityKorea Department of Architectural Engineering Pusan National UniversityDoctor of EngineeringKorea

General regular shaped diagrid structures can express diverse shapes because braces are installed along the exterior faces of the structures and the structures have no columns. However, since irregular shaped structures have diverse variables, studies to assess behaviors resulting from various variables are continuously required to supplement the imperfections related to such variables. In the present study, materials elastic modulus and yield strength were selected as variables for strength that would be applied to diagrid structural systems in the form of Twisters among the irregular shaped buildings classified by Vollers and that affect the structural design of these structural systems. The purpose of this study is to conduct sensitivity analysis for axial rotation diagrid structural systems according to changes in brace angles in order to identify the design variables that have relatively larger effects and the tendencies of the sensitivity of the structures according to changes in brace angles and axial rotation angles.

关键词： sensitivity analysis axial rotation-diagrid structure lateral behaviors

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Effects of initial texture on deformation behavior during cold rolling and static recrystallization during subsequent annealing of AZ31 alloy

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Journal of Materials Science & Technology 2021年第7期66卷 139-149页

作者： Sang Won Lee Gukin han Tea-sung Jun sung Hyuk Park School of Materials Science and Engineering.Kyungpook National University Daegu 41566Republic of Korea Department of Mechanical Engineering Incheon National UniversityIncheon 22012Republic of Korea

This study demonstrates that the initial texture of Mg alloy significantly affects the microstructure developed during cold rolling and the recrystallization behavior during subsequent annealing. In a sample with a texture oriented toward the normal direction(ND sample), thick and large-sized shear bands are intensively formed during cold rolling and the deformation is strongly localized along these bands. In contrast,in a sample with a texture oriented toward the transverse direction(TD sample), many {10-12} twins are formed at the early stage of cold rolling, and then, numerous small-sized shear bands are formed in these twins. Results of nanoindentation tests reveal that the cold-rolled ND sample has internal strain energy that is substantially concentrated along the shear bands, whereas the cold-rolled TD sample has a large amount of internal strain energy that is homogeneously distributed throughout the material;this latter behavior is strongly related to the extensive {10-12} twinning and the resultant microstructural variations in the TD sample. During subsequent annealing, recrystallization occurs locally along the shear bands in the ND sample, which leads to the formation of a bimodal grain structure comprising fine recrystallized grains and coarse unrecrystallized grains. In contrast, during subsequent annealing of the TD sample, static recrystallization occurs homogeneously throughout the material, which results in the formation of a uniform grain structure that mostly comprises equiaxed recrystallized grains.

关键词： Magnesium alloy Cold rolling Initial texture Twinning Static recrystallization

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Factors associated with axial length elongation in high myopia in adults

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International Journal of Ophthalmology(English edition) 2021年第8期14卷 1231-1236页

作者： Hong Kyu Kim sung soo Kim Department of Ophthalmology Dankook University HospitalDankook University College of MedicineCheonan 31116Republic of Korea Yonsei University Graduate School of Medicine Seoul 03722Republic of Korea Department of Ophthalmology Severance HospitalInstitute of Vision ResearchYonsei University College of MedicineSeoul 03722Republic of Korea

AIM:To investigate the association of axial length(AL)and ocular factors on AL ***:A retrospective chart review of patients who underwent two or more AL examinations for more than two *** 4 groups were divided according to initial AL(hanged in the groups with AL<24 mm and 24≤AL<26 *** the contrary,AL increased by 0.011 mm/y in the group with 26≤AL<28 mm and 0.035 mm/y in the group with AL≥28 mm(P<0.001).In high myopia,AL elongation increased in eye with longer AL(r=0.003,P=0.024),female gender(r=0.014,P=0.019),eye with larger peripapillary chorioretinal atrophic area(r=0.002,P=0.019),and smaller vascular arcade angle(r=-0.004,P=0.006).The risk of elongation 0.03 mm/y in high myopia was increased in female gender(P=0.040),and gradually increased in eye with large peripapillary chorioretinal atrophy area(P<0.01).CONCLUSION:AL elongate significantly in the eye with longer AL,female gender,and the eye with larger atrophic area and smaller arcade angle on fundus photography.

关键词： axial length elongation fundus photography high myopia myopic complication

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Fingerprint inspired advanced end-effector and its applications

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Friction 2022年第10期10卷 1739-1750页

作者： sung Ho LEE Hyo sung KIM han Jun PARK Moon Kyu KWAK Department of Electrical Engineering and Computer Science University of MichiganAnn Arbor 48109USA Department of Mechanical Engineering Kyungpook National UniversityDaegu 41566Republic of Korea

The human fingertip consists of a fingerprint with many micro-grating *** main roles of the fingerprint could be divided into two purposes,namely,the enhancement of the frictional force and the effective transmittance of the *** this study,we present the fingerprint-inspired end-effector that has not only admirable frictional force but also electric *** end-effector is composed of fluorocarbon rubber,one of the famous materials to achieve high frictional force and *** various experiments,the novel performance of micro structured fluorocarbon rubber end-effector(MSFE)is characterized by comparing with a macroscale patterned sample(MPS),which has been already used in real industrial *** results are analyzed ***,as feasible applications,we suggest two applications based on the role of the *** is the conductive astronaut glove with high frictional force,and the other one is a non-slip pad for the next-generation glass transfer *** these experiments,we successfully observe the enhanced system performance and confirm the possibility of using the MSFE as feasible *** believe that the MSFE could be a useful and powerful alternative as an end-effector,not only in the aerospace industry but also in display manufacturing processes.

关键词： fingerprint end-effector fluorocarbon rubber(FKM) glass transfer system spacesuit

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Clinical importance and surgical decision-making regarding proximal resection margin for gastric cancer

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World Journal of Gastrointestinal Oncology 2013年第1期5卷 4-11页

作者： Doosup Shin sung-soo Park Department of Surgery Korea University College of Medicine Division of Upper GI Surgery Department of SurgeryKorea University College of MedicineMIS and Robotic Surgery Center Korea University Medical Center Korea University Anam Hospital

Because of the intramural spread of gastric cancer,a sufficient length of a resection margin has to be attained to ensure complete excision of the *** has been debate on an adequate length of proximal resection margin(PRM) and its related ***,the objective of this article is to review several studies on PRM and to summarize the current evidence on the *** there is some discrepancy in the recommended values for PRM between authors,a PRM of more than 2-3 cm for early gastric cancer and 5-6 cm for advanced gastric cancer is thought to be *** the margin is confirmed to be clear,however,the length of PRM measured in postoperative pathologic examination does not affect the patient's survival,even when it is shorter than the recommended ***,the recommendations for PRM length should be applied only to intraoperative decision-making to prevent positive margins on the final *** that a negative resection margin is the ultimate goal of determining an adequate PRM,development and improvement of reliable methods to confirm a negative resection margin intraoperatively would minimize the extent of surgery and offer a better quality of life to more *** the same context,special attention has to be paid to patients who have advanced stage or diffuse-type gastric cancer,because they are more likely to have a positive ***,a wider excision with intraoperative frozen section(IFS) examination of the resection margin is *** all the attempts to avoid positive margins,there is still a certain rate of positive-margin *** the negative impact of a positive margin on prognosis is mostly obvious in low N stage patients,aggressive further management,such as extensive re-operation,is required for these *** conclusion,every possible preoperative and intraoperative evaluation should be thoroughly carried out to identify in advance the patients with a high risk of having positive margins;the

关键词： Resection margin Proximal resection margin Negative resection margin Positive resection margin Gastrectomy Gastric cancer

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Comparative study on multibody vehicle dynamics models based on subsystem synthesis method using Cartesian and joint coordinates

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Theoretical & Applied Mechanics Letters 2012年第6期2卷 65-70页

作者： sung soo Kim Wan Hee Jeong Myung Ho Kim Jong Boo han Department of Mechatronics Engineering Chungnam National University 220 Kung-DongYuseong-GuDaejeon 305-764Korea Graduate School of Mechanical Mechanical DesignMechatronics EngineeringChungnam National UniversityDaejeon 305-764Korea Korea Institute of Machinery and Materials Daejeon 305-764Korea

The subsystem synthesis method has been developed in order to improve computational efficiency for a multibody vehicle dynamics model. Using the subsystem synthesis method, equations of motion of the base body and each subsystem can be solved separately. In the subsystem synthesis method, various coordinate systems can be used and various integration methods can be applied in each subsystem, as long as the effective mass matrix and the effective force vector are properly produced. In this paper, comparative study has been carried out for the subsystem synthesis method with Cartesian coordinates and with joint relative coordinates. Two different integration methods such as an explicit integrator and an explicit implicit integrator are employed. In order to see the accuracy and computational efficiency from the different models based on the different coordinate systems and different integration methods, a rough terrain run simulations has been carried out with a 6 × 6 off-road multibody vehicle model.

关键词： subsystem synthesis method differential algebraic equations

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Recovery of an injured ascending reticular activating system with recovery from a minimally conscious state to normal consciousness in a stroke patient: a diffusion tensor tractography study

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Neural Regeneration Research 2020年第9期15卷 1767-1768页

作者： sung Ho Jang han Do Lee Department of Physical Medicine and Rehabilitation College of MedicineYeungnam UniversityDaeguRepublic of Korea Department of Physical Therapy College of Natural ScienceUlsan College UniversityUlsanRepublic of Korea

Consciousnessiscontrolledbytheascendingreticularactivating system (ARAS)(Teasdale and Jennett, 1974;Jang and Lee, 2015;Jang et al., 2016a). Scientific medical strategies for recovery in patients with impaired consciou... 详细信息

关键词： impaired system consciousness

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Easy calibration method of vision system for in-situ measurement of strain of thin films

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中国有色金属学会会刊：英文版 2009年第B09期19卷 243-249页

作者： Jun-Hyub PARK Dong-Joong KANG Myung-soo SHIN sung-Jo LIM Son-Cheol YU Kwang-soo LEE Jong-Eun HA sung-Hoon CHOA Department of Mechatronics Engineering Tongmyong University School of Mechanical Engineering Pusan National University Department of Automotive Engineering Hoseo University Department of Automotive Engineering Seoul National University of Technology Department of Nano/IT Engineering Seoul N ational University of Technology

An easy calibration method was presented for in-situ measurement of displacement in the order of nanometer during micro-tensile test for thin films by using CCD camera as a sensing device. The calibration of the sensing camera in the system is a central element part to measure displacement in the order of nanometer using images taken with the camera. This was accomplished by modeling the optical projection through the camera lens and relative locations between the object and camera in 3D space. A set of known 3D points on a plane where the film is located on is projected to an image plane as input data. These points, known as a calibration points, are then used to estimate the projection parameters of the camera. In the measurement system of the micro-scale by CCD camera, the calibration data acquisition and one-to-one matching steps between the image and 3D planes need precise data extraction procedures and repetitive user's operation to calibrate the measuring devices. The lack of the robust image feature extraction and easy matching prevent the practical use of these methods. A data selection method was proposed to overcome these limitations and offer an easy and convenient calibration of a vision system that has the CCD camera and the 3D reference plane with calibration marks of circular type on the surface of the plane. The method minimizes the user's intervention such as the fine tuning of illumination system and provides an efficient calibration method of the vision system for in-situ axial displacement measurement of the micro-tensile materials.

关键词：标定方法视觉系统原位测试应变薄膜松

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