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Benign gallbladder diseases:Imaging techniques and tips for differentiating with malignant gallbladder diseases

World Journal of Gastroenterology 2020年第22期26卷 2967-2986页

作者： Mi Hye Yu Young Jun Kim Hee Sun Park sung il jung Department of Radiology Konkuk University Medical CenterKonkuk University School of Medicine120-1 Neungdong-roGwangjin-guSeoul 05030South Korea

Benign gallbladder diseases usually present with intraluminal lesions and localized or diffuse wall *** lesions of the gallbladder include gallstones,cholesterol polyps,adenomas,or sludge and polypoid type of gallbladder cancer must subsequently be *** size,stalk width,and enhancement intensity on contrast-enhanced ultrasound and degree of diffusion restriction may help differentiate cholesterol polyps and adenomas from gallbladder *** gallbladder wall thickening is largely due to segmental or focal gallbladder adenomyomatosis,although infiltrative cancer may present *** of Rokitansky-Aschoff sinuses is pivotal in diagnosing *** layered pattern,degree of enhancement,and integrity of the wall are imaging clues that help discriminate innocuous thickening from gallbladder ***-resolution ultrasound is especially useful for analyzing the layering of gallbladder wall.A diffusely thickened wall is frequently seen in inflammatory processes of the ***,it is important to check for coexistent cancer in instances of acute *** used alone is limited in evaluating complicated cholecystitis and often requires complementary computed *** chronic cholecystitis,preservation of a two-layered wall and weak wall enhancement are diagnostic clues for excluding *** resonance imaging in conjunction with diffusion-weighted imaging helps to differentiate xathogranulomatous cholecystitis from gallbladder cancer by identifying the presence of fat and degree of diffusion *** distinctions require a familiarity with typical imaging features of various gallbladder diseases and an understanding of the roles that assorted imaging modalities play in gallbladder evaluations.

关键词： Cholesterol polyp Gallbladder adenoma Adenomyomatosis Cholecystitis Xathogranulomatous cholecystitis Gallbladder cancer Imaging techniques

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Three-Tesla magnetic resonance elastography for hepatic fibrosis:Comparison with diffusion-weighted imaging and gadoxetic acid-enhanced magnetic resonance imaging

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World Journal of Gastroenterology 2014年第46期20卷 17558-17567页

作者： Hee Sun Park Young Jun Kim Mi Hye Yu Won Hyeok Choe sung il jung Hae Jeong Jeon Department of Radiology Konkuk University School of MedicineSeoul 143-729South Korea Digestive Disease Center Konkuk University School of MedicineSeoul 143-729South Korea

AIM: To evaluate the feasibility of 3-Tesla magnetic resonance elastography (MRE) for hepatic fibrosis and to compare that with diffusion-weighted imaging (DWI) and gadoxetic acid-enhanced magnetic resonance (MR) imag... 详细信息

关键词： Magnetic resonance elastography Hepatic fibrosis Diffusion weighted imaging Gadoxetic acid enhanced magnetic resonance imaging Serum markers

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Assessing significant fibrosis using imaging-based elastography in chronic hepatitis B patients: Pilot study

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World Journal of Gastroenterology 2019年第25期25卷 3256-3267页

作者： Hee Sun Park Won Hyeok Choe Hye Seung Han Mi Hye Yu Young Jun Kim sung il jung Jeong Han Kim So Young Kwon Department of Radiology Konkuk University School of MedicineSeoul 05030South Korea Department of Internal Medicine Konkuk University School of MedicineSeoul 05030South Korea Department of Pathology Konkuk University School of MedicineSeoul 05030South Korea

BACKGROUND Accurate detection of significant fibrosis(fibrosis stage 2 or higher on the METAVIR scale)is important especially for chronic hepatitis B(CHB)patients with high viral loads but with normal or mildly elevated alanine aminotransferase(ALT)levels because the presence of significant fibrosis is accepted as the indication for antiviral *** biopsy is the reference standard for diagnosing significant fibrosis,but it is an invasive ***,noninvasive imaging-based measurements,such as magnetic resonance elastography(MRE)or two-dimensional shear-wave elastography(2DSWE),have been proposed for the quantitative assessment of liver *** To explore MRE and 2D-SWE to identify fibrosis stage,and to compare their performance with that of serum-based *** The study enrolled 63 treatment-na?ve CHB patients with high viral loads but with normal or mildly elevated ALT levels who underwent liver biopsy before a decision was made to initiate antiviral *** and 2D-SWE were performed,and serum-based indices,such as FIB-4 and aspartate transaminase to platelet ratio index(APRI),were *** diagnostic performances of MRE,2D-SWE,FIB-4,and APRI for assessing significant fibrosis(≥F2)and cirrhosis(F4)were evaluated with liver histology as the reference standard,using receiver operating characteristic *** The liver fibrosis stage was F0/F1 in 19,F2 in 14,F3 in 14,and F4 in 16 patients,*** significantly discriminated F2 from F0/1(P=0.022),whereas 2D-SWE showed a broad overlap in distinguishing those *** showed a higher correlation coefficient value with fibrosis stage than 2D-SWE with fibrosis stage(0.869 vs 0.649,Spearman test;P<0.001).Multivariate linear regression analyses showed that fibrosis stage was the only factor affecting the values of MRE(P<0.001),whereas body mass index(P=0.042)and fibrosis stage(P<0.001)were independent factors affecting 2D-SWE *** performance for diagnos

关键词： Antiviral therapy Chronic hepatitis B Liver fibrosis Magnetic resonance elastography Ultrasound elastography

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Possibility of Solid Hydrometeor Growth Zone Identification Using Radar Spectrum Width

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Advances in Atmospheric Sciences 2023年第2期40卷 317-332页

作者： sung-Ho SUH Eun-Ho CHOI Hong-il KIM Woonseon jung Flight Safety Technology Division NARO Space CenterKorea Aerospace Research Institute(KARI)508 Haban-roBongrae-myeonGoheung-gunJeollanam-do 59571Republic of Korea Research Applications Department National Institute of Meteorological Sciences33Seohobuk-roSeoqwipo-siJeju-do 63568Republic of Korea

In this study,the correlation between simulated and measured radar velocity spectrum width(σ_(v))is *** results show that the dendrites growth zones(DGZs)and needles growth zones(NGZs)mostly contain dendrites(DN)and needles(NE),***σ_(v) zones(1.11.2 m s^(-1),a differential reflectivity(ZDR)higher than 0 dB,and a cross-correlation coefficient(ρhv)less than *** contrast,prolate particles with relatively uniform shapes were observed in the NGZ withσ_(v)<0.6 m s^(-1),a ZDR less than 0 dB,andρhv higher than *** simulation results show that the DN exhibited a largerσ_(v) compared to the NE,and this observedσ_(v) was strongly dependent on the wind fluctuations(v’)due to turbulence or wind *** contrast,the NE exhibited a significantly smallσ_(v)~0.55 m s^(-1),which converges irrespective of v’.In addition,a strong correlation between the measuredσ_(v) values at five radar elevation angles(θ=6.2°,9.1°,13.1°,19°,and 80°)and those simulated in this study confirmed the significance of the analysis results.

关键词： spectrum width weather radar aerodynamic properties dendritic growth zone hydrometeor classifications

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Gene expression analysis of primary normal human hepatocytes infected with human hepatitis B virus

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World Journal of Gastroenterology 2006年第31期12卷 4986-4995页

作者： Hyun Mi Ryu sung Gyoo Park sung Su Yea Won Hee Jang Young-il Yang Guhung jung School of Biological SciencesSeoul National University Seoul151-742Korea School of Biological Sciences and Institute of MicrobiologySeoul National University Seoul151-742Korea The Paik-Inje Memorial Institute for Biomedical ScienceInje University Pusanjin-guPusan 614-735Korea Department of PathologyCollege of Medicine Inje UniversityPaik HospitalPusan 614-735Korea

AIM： To find the relationship between hepatitis B virus （HBV） and hepatocytes during the initial state of infection by cDNA microarray. METHODS： Primary normal human hepatocytes （PNHHs） were isolated and infected with HBV. From the PNHHs, RNA was isolated and inverted into complement DNA （cDNA） with Cy3- or Cy5- labeled dUTP for microarray analysis. The labeled cDNA was hybridized with microarray chip, including 4224 cDNAs. From the image of the microarray, expression profiles were produced and some of them were confirmed by RT-PCR, immunoblot analysis, and NF-κB luciferase reporter assay. RESULTS： From the cDNA microarray, we obtained 98 differentially regulated genes. Of the 98 genes, 53 were up regulated and 45 down regulated. Interestingly, in the up regulated genes, we found the TNF signaling pathway-related genes： LT-α, TRAF2, and NIK. By using RT-PCR, we confirmed the up-regulation of these genes in HepG2, HuhT, and Chang liver cells, which were transfected with pHBV1.2x, a plasmid encoding all HBV messages. Moreover, these three genes participated in HBV- mediated NF-κB activation. CONCLUSION： During the initial state of HBV infection, hepatocytes facilitate the activation of NF-κB through up regulation of LT-α, TRAF2, and NIK.

关键词： cDNA microarray Primary normal human hepatocytes LT-α TRAF2 NIK NF-κB

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Sequential transcatheter arterial chemoembolization and portal vein embolization before right hemihepatectomy in patients with hepatocellular carcinoma

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Hepatobiliary & Pancreatic Diseases International 2020年第3期19卷 244-251页

作者： Gil Chun Park sung Gyu Lee Young In Yoon Kyu Bo sung Gi Young Ko Dong il Gwon Dong Hwan jung Yong Kyu jung Division of Hepatobiliary Surgery and Liver Transplantation Department of SurgeryAsan Medical CenterUniversity of Ulsan College of MedicineSeoulKorea Department of Radiology and Research Institute of Radiology Asan Medical CenterUniversity of Ulsan College of MedicineSeoulKorea

Background:Recent studies showed that sequential selective transcatheter arterial chemoembolization(TACE)and portal vein embolization(PVE)provided better future liver remnant(FLR)regeneration rate and disease-free survival following surgery compared with PVE *** present study aimed to clarify whether preoperative sequential TACE and PVE before right hemihepatectomy can reduce postoperative hepatocellular carcinoma(HCC)recurrence and improve long-term disease-free and overall ***:Recurrence and survival outcomes were retrospectively evaluated in 205 patients with HCC who underwent right hemihepatectomy by a single surgeon from November 1993 to November *** were divided into four groups according to the procedure performed before the surgery:sequential TACE and PVE(TACE-PVE),PVE-only,TACE-only,or na?ve control *** baseline patient and tumor characteristics,postoperative outcomes,recurrence-free survival and overall survival were ***:Baseline patient and tumor characteristics upon diagnosis were similar in all four groups,while sequential TACE and PVE were well *** TACE-PVE group had a higher mean increase in percentage FLR volume compared with that of the PVE-only group(17.46%±6.63%vs.12.14%±5.93%;P=0.001).The TACE-PVE group had significantly better overall and disease-free survival rates compared with the other groups(both P<0.001).Conclusions:Sequential TACE and PVE prior to surgery can be an effective therapeutic strategy for patients with HCC scheduled for major hepatic *** active application of preoperative sequential TACE and PVE for HCC would allow more patients with marginal FLR volume to become candidates for major hepatic resection by promoting compensatory FLR hypertrophy without the deterioration of basal hepatic functional reserve or tumor progression.

关键词： Sequential selective transcatheter Arterial chemoembolization Portal vein embolization Hepatocellular carcinoma Future liver remnant

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Geometry effect on mechanical properties of woven fabric composites

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Journal of Central South University 2011年第6期18卷 1985-1993页

作者： KIM Myungsoo SONG jung-il School of Mechatronics Changwon National University

The effects of geometry on mechanical properties in woven fabric composites were explored. Two types of composites, including one-layered and two-layered composites, were designed and studied. For one-layered composites, inter-strand gap effects on the mechanical properties were studied, while three cases of geometries with inter-strand gaps in two-layered composites were evaluated. A woven fiber micromechanics analytical model called MESOTEX was employed for theoretical simulation. The predicted results show that the inter-strand gap and simple variation of the strand positions in a repeating unit cell significantly affect the mechanical properties of woven fabric composites.

关键词： woven fabric composites inter-strand gap mechanical properties micromechanics modeling

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Utilizing Blockchain Technology to Improve WSN Security for Sensor Data Transmission

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Computers, Materials & Continua 2021年第8期68卷 1899-1918页

作者： sung-jung Hsiao Wen-Tsai sung Department of Information Technology Takming University of Science and TechnologyTaipei City11451Taiwan Department of Electrical Engineering National Chin-Yi University of TechnologyTaichung41170Taiwan

This paper proposes a method for improving the data security of wireless sensor networks based on blockchain *** technology is applied to data transfer to build a highly secure wireless sensor *** this network,the relay stations use microcontrollers and embedded devices,and the microcontrollers,such as Raspberry Pi and Arduino Yun,represents mobile *** proposed system uses microcontrollers to facilitate the connection of various sensor *** adopting blockchain encryption,the security of sensing data can be effectively improved.A blockchain is a concatenated transaction record that is protected by *** section contains the encrypted hash of the previous section,the corresponding timestamp,and transaction *** transaction data denote the sensing data of the wireless sensing *** proposed system uses a hash value representation calculated by the Merkel-tree algorithm,which makes the transfer data of the system difficult to be tamped ***,the proposed system can serve as a private cloud data *** this study,the system visualizes the data uploaded by sensors and create relevant charts based on big data *** the webpage server of the proposed system is built on an embedded operating system,it is easy to model and visualize the corresponding graphics using Python or JavaScript programming ***,this study creates an embedded system mobile database and web server,which can utilize JavaScript program language and *** runtime environment to apply blockchain technology to mobile *** proposed method is verified by the experiment using about 1600 data *** results show that the possibility of data being changed is very small,and the probability of data being changed is almost zero.

关键词： Blockchain embedded system big data analysis python javascript node.js

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Improving Speech Enhancement Framework via Deep Learning

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Computers, Materials & Continua 2023年第5期75卷 3817-3832页

Speech plays an extremely important role in social *** individuals suffer from a“speech barrier,”which limits their communication with *** this study,an improved speech recognitionmethod is proposed that addresses the needs of speech-impaired and deaf individuals.A basic improved connectionist temporal classification convolutional neural network(CTC-CNN)architecture acoustic model was constructed by combining a speech database with a deep neural *** sensors were used to convert the collected voice signals into text or corresponding voice signals to improve *** method can be extended to modern artificial intelligence techniques,with multiple applications such as meeting minutes,medical reports,and verbatim records for cars,sales,*** experiments,a modified CTC-CNN was used to train an acoustic model,which showed better performance than the earlier common *** a CTC-CNN baseline acoustic model was constructed and optimized,which reduced the error rate to about 18%and improved the accuracy rate.

关键词： Artificial intelligence speech recognition speech to text CTC-CNN

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RFID Positioning and Physiological Signals for Remote Medical Care

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Computer Systems Science & Engineering 2022年第4期41卷 289-304页

作者： Wen-Tsai sung sung-jung Hsiao Department of Electrical Engineering National Chin-Yi University of TechnologyTaichung411030Taiwan Department of Information Technology Takming University of Science and TechnologyTaipei City11451Taiwan

The safety of patients and the quality of medical care provided to them are vital for their *** study establishes a set of RFID(Radio Fre-quency Identiﬁcation)-based systems of patient care based on physiological sig-nals in the pursuit of a remote medical care *** RFID-based positioning system allows medical staff to continuously observe the patient's health and *** staff can thus respond to medical emergencies in time and appropriately care for the *** the COVID-19 pandemic broke out,the proposed system was used to provide timely information on the location and body temperature of patients who had been screened for the *** results of experiments and comparative analyses show that the proposed system is superior to competing systems in *** use of remote monitoring technology makes user interface easier to provide high-quality medical services to remote areas with sparse populations,and enables better care of the elderly and patients with mobility *** can be found from the experiments of this research that the accuracy of the position sensor and the ability of package delivery are the best among the other related *** presentation of the graphical interface is also the most cordial among human-computer interaction and the operation is simple and clear.

关键词： Remote medical care active RFID positioning physiological signal

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