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Clinical Efficacy and Safety of Miniscalpel-Needle Treatment for Tension-Type Headache:A Systematic Review and Meta-Analysis

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Chinese Journal of Integrative Medicine 2020年第9期26卷 713-720页

作者： Chan-Young Kwon Sang-Hoon Yoon sun-yong chung Jong Woo Kim Department of Clinical Korean Medicine Graduate SchoolKyung Hee U niversitySeoul(02447)Republic of Korea chung-Yeon Central Institute Gwang-juRepublic of Korea Department of Oriental Neuropsychiatry Kyung Hee University Hospital at GangdongSeoul(02447)Republic of Korea

Objective:To investigate the clinical efficacy and safety of miniscalpel-needle(MSN)treatment for tension-type headache(TTH).Method:Seven medical databases were searched to identify randomized controlled trials(RCTs)evaluating the effect and safety of MSN *** articles published up to November 15,2018 were retrieved.A meta-analysis was conducted for the included studies,and the risk of bias was *** outcomes were visual analogue scale(VAS)or numeric rating scale(NRS)*** outcomes were clinical effective rates including total effective rate(TER),markedly effective rate(MER),and totally cured rate(TCR)determined by improvement in clinical symptoms or VAS scores,the frequency of adverse events(AEs)that occurred during the study,and participant quality of life(QOL).Results:Seven RCTs involving 724 participants were *** treatment showed significantly higher MER and TCR[relative risk(RR)1.27,95%confidence interval(Cl)1.01 to 1.61;RR 1.31,95%Cl 1.09 to 1.57,respectively],but not TER(RR 1.03,95%Cl 0.96 to 1.10)compared to *** treatment plus conventional treatment showed significant lower VAS and higher TER,MER,and TCR(mean difference-3.54,95%Cl-3.80 to-3.28;RR 1.14,95%Cl 1.06 to 1.23;RR 2.31,95%Cl 1.50 to 3.58;RR 3.01,95%Cl 2.25 to 4.02,respectively)compared to conventional ***:According to current evidence,MSN treatment as a monotherapy or as an adjunctive treatment to other existing treatments might have benefits on treating ***,since the number and the sample size of studies included were both small and the methodological quality was poor,the findings of this review should be interpreted with great caution,and our confidence in the results is low.A high quality RCT using objective outcomes should be performed on this topic.

关键词： acupuncture acupotomy tension-type headache systematic review meta-analysis

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Anti-anger Effects of Herbal Medicine:A Mini-Review of Rat Studies

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Chinese Journal of Integrative Medicine 2022年第3期28卷 263-271页

作者： Chan-Young Kwon Hyo-Weon Suh Jong Woo Kim sun-yong chung Department of Oriental Neuropsychiatry Dong-eui University College of Korean MedicineBusan(47227)Republic of Korea Department of Neuropsychiatry Kyung Hee University KoreanMedicine Hospital at Gangdong892 Dongnam-roGangdong-guSeoul(05278)Republic of Korea

Objective:To analyze the available data on the anti-anger effects of herbal medicines(HMs)as well as their underlying mechanisms in rat ***:From 6 electronic databases[PubMed,EMBASE,China National Knowledge Infrastructure(CNKI),Wanfang,Oriental Medicine Advanced Searching Integrated System(OASIS),and Research Information Sharing Service(RISS)],relevant animal experiments were searched by using"anger,""rats,"and"animal"as search *** last search was conducted on November 22,2019,and all experiments involving rat models of anger and treatment using HMs published until the date of the search were ***:A total of 24 studies with 16 kinds of HMs were *** studies have used the tail irritating method and"social isolation and resident intruder"method to establish anger *** to the included studies,the therapeutic mechanisms of HMs for anger regulation and important herbs by their frequency and/or preclinical evidence mainly incladed regulation of hemorheology(Bupleuri Radix,Paeoniae Radix Alba,and Glycyrrhizae Radix),regulation of sex hormones(Bupleuri Radix,Cyperi Rhizoma,and Paeoniae Radix Alba),regulation of neurotransmitters(Cyperi Rhizoma),regulation of anger-related genes(Bupleuri Radix,Glycyrrhizae Radix,and Paeoniae Radix Alba),and other ***,Liver(Gan)qi-smoothing herbs including Bupleuri Radix and Cyperi Rhizoma were the most frequently ***:This review found the frequent methods to establish an anger model,and major mechanisms of anti-anger effects of ***,some Liver qi-smoothing herbs have been frequently used to investigate the anti-anger effects of *** findings provide insight into the role and relevance of HMs in the field of anger management.

关键词： anger anger management therapy herbal medicine Korean traditional medicine

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Amomum villosum induces longitudinal bone growth in adolescent female rats

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Journal of Traditional Chinese Medicine 2012年第3期32卷 453-458页

作者： sun Haeng Lee Ji Young Kim Hocheol Kim Seul Ki Park Cho Young Kim sun yong chung Gyu Tae Chang Department of Pediatrics of Korean Medicine Kyung Hee University Hospital at Gang-dong892 Dongnam-roGangdong-guSeoul 134-727Republic of Korea Department of Herbal Pharmacology College of Korean MedicineKyung Hee University26 Kyungheedae-roDongdaemoon-guSeoul 130-701Republic of Korea Department of Neuropsychiatry of Korean Medicine Kyung Hee University Hospital at Gang-dong892 Dongnam-roGangdong-guSeoul 134727Republic of Korea

OBJECTIVE:This study was conducted to evaluate the effect of Amomum villosum on longitudinal bone ***:Adolescent female Sprague-Dawley rats were divided into 3 groups and treated for 4 days:control(distilled water,p.o.),recombinant human growth hormone(rhGH;100 μg/kg,s.c.),and ***(500 mg/kg,p.o.) *** day 3,tetracycline(20 g/kg,i.p.) was injected for growth plate *** days 2,3 and 4,5-bromo-2'-deoxyuridine(BrdU)(50 mg/kg,i.p.) was injected to label proliferating *** day 5,tibias were dissected and fixed in 4% paraformaldehyde,dehydrated,and sectioned for immunohistochemistry and ***:The rate of bone growth in the *** and rhGH groups increased to(410 ± 44) and(389 ± 46) μm/day(P<0.01),respectively,as compared with the control(330.7 ± 34.7) μm/*** thickness of the growth plates also increased to(591 ± 37) and(598 ± 32) μm,respectively,as compared with the control(524± 89) μm(P<0.001).The number of BrdU-positive cells in the chondrocytes of the *** and rhGH groups was also significantly higher(126±24) and(143±18) cells/mm 2,respectively) than in the control(109 ± 25) mm 2(P<0.05).Insulin-like growth factor-1 and bone morphogenetic protein-2 in the *** and rhGH groups were highly expressed in the growth plate as compared with the control samples,indicating increased bone ***:*** could be used to treat growth retardation during adolescence.

关键词： Amomum villosum Growth plate Bone Development Recombinant human growth hormone

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Dual‑Donor‑Induced Crystallinity Modulation Enables 19.23% Efficiency Organic Solar Cells

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Nano-Micro Letters 2025年第3期17卷 376-388页

作者： Anhai Liang Yuqing sun Sein chung Jiyeong Shin Kangbo sun Chaofeng Zhu Jingjing Zhao Zhenmin Zhao Yufei Zhong Guangye Zhang Kilwon Cho Zhipeng Kan Center On Nanoenergy Research Institute of Science and Technology for Carbon Peak&NeutralitySchool of Physical Science&TechnologyGuangxi UniversityNanning 530004People’s Republic of China Department of Chemical Engineering Pohang University of Science and TechnologyPohang 37673South Korea College of New Materials and New Energies Shenzhen Technology UniversityShenzhen 518118People’s Republic of China Zhejiang Engineering Research Center for Fabrication and Application of Advanced Photovoltaic Materials School of Materials Science and EngineeringNingboTech UniversityNingbo 315100People’s Republic of China State Key Laboratory of Featured Metal Materials and Life-Cycle Safety for Composite Structures Nanning 530004People’s Republic of China

Trap-assisted charge recombination is one of the primary limitationsof restricting the performance of organic solar cells. However, effectivelyreducing the presence of traps in the photoactive layer remains ***, wide bandgap polymer donor PTzBI-dF is demonstrated as an effectivemodulator for enhancing the crystallinity of the bulk heterojunction active layerscomposed of D18 derivatives blended with Y6, leading to dense and orderedmolecular packings, and thus, improves photoluminescence quenching *** a result, the photovoltaic devices exhibit reduced trap-assisted charge recombinationlosses, achieving an optimized power conversion efficiency of over 19%.Besides the efficiency enhancement, the devices comprised of PTzBI-dF as athird component simultaneously attain decreased current leakage, improved chargecarrier mobilities, and suppressed bimolecular charge recombination, leading toreduced energy losses. The advanced crystalline structures induced by PTzBI-dFand its characteristics, such as well-aligned energy level, and complementaryabsorption spectra, are ascribed to the promising performance *** findings suggest that donor phase engineering is a feasible approach to tuning the molecular packings in the active layer, providingguidelines for designing effective morphology modulators for high-performance organic solar cells.

关键词： Trap-assisted charge recombination Photoluminescence Miscibility Current leakage Power conversion efficiency

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Crystallization Modulation and Holistic Passivation Enables Efficient Two‑Terminal Perovskite/CuIn(Ga)Se_(2)Tandem Solar Cells

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Nano-Micro Letters 2025年第1期17卷 205-215页

作者： Cong Geng Kuanxiang Zhang Changhua Wang chung Hsien Wu Jiwen Jiang Fei Long Liyuan Han Qifeng Han Yi‑Bing Cheng yong Peng State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070People’s Republic of China Triumph Photovoltaic Materials Co. Ltd.No.1001 Yannan AvenueHigh‑Tech Development DistrictBengbuAnhui 233000People’s Republic of China College of Materials Science and Engineering Guilin University of TechnologyGuilin 541004People’s Republic of China State Key Laboratory of Metal Matrix Composites Shanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

Two-terminal(2-T)perovskite(PVK)/CuIn(Ga)Se_(2)(CIGS)tandem solar cells(TSCs)have been considered as an ideal tandem cell because of their best bandgap matching regarding to Shockley–Queisser(S–Q)***,the nature of the irregular rough morphology of commercial CIGS prevents people from improving tandem device *** this paper,D-homoserine lactone hydrochloride is proven to improve coverage of PVK materials on irregular rough CIGS surfaces and also passivate bulk defects by modulating the growth of PVK *** addition,the minority carriers near the PVK/C60 interface and the incompletely passivated trap states caused interface recombination.A surface reconstruction with 2-thiopheneethylammonium iodide and N,N-dimethylformamide assisted passivates the defect sites located at the surface and grain ***,LiF is used to create this field effect,repelling hole carriers away from the PVK and C60 interface and thus reducing *** a result,a 2-T PVK/CIGS tandem yielded a power conversion efficiency of 24.6%(0.16 cm^(2)),one of the highest results for 2-T PVK/CIGS TSCs to our *** validation underscores the potential of our methodology in achieving superior performance in PVK/CIGS tandem solar cells.

关键词： PVK/CIGS TSCs Irregular rough surfaces Modulating the growth PVK/C60 interface recombination

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Depression mechanism of sulfite ions on sphalerite and Pb^(2+)activated sphalerite in the flotation separation of galena from sphalerite

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 335-345页

作者： Feng Zhang Chenyang Zhang Linlin Wu Wei sun Hongliang Zhang Jianhua Chen yong Pei Songjiang Li Engineering Research Center of Ministry of Education for Carbon Emission Reduction in Metal Resource Exploitation and Utilization Hunan International Joint Research Center for Efficient and Clean Utilization of Critical Metal Mineral ResourcesSchool of Minerals Processing and BioengineeringCentral South UniversityChangsha 410083China State Key Laboratory of Mineral Processing Beijing General Research Institute of Mining&MetallurgyBeijing 100160China Hunan Provincial Key Laboratory of Micro&Nano Materials Interfaces Science College of Chemistry and Chemical EngineeringCentral South UniversityChangsha 410083China School of Resources Environment and MaterialsGuangxi UniversityNanning 530004China Department of Chemistry Xiangtan UniversityXiangtan 411105China China Railway Resource Group Co.Ltd Beijing 102300China

The depression mechanism of sulfite ions on sphalerite and Pb^(2+)activated sphalerite in the flotation separation of galena from sphalerite still lacked in-depth ***,the depression mechanism of sulfite ions on sphalerite and Pb^(2+)activated sphalerite in the flotation separation of galena from sphalerite was further systematically investigated with experiments and density functional theory(DFT)*** X-ray photoelectric spectroscopy(XPS)results,DFT calculation results,and frontier molecular orbital analysis indicated that sulfite ions were difficult to be adsorbed on sphalerite surface,suggesting that sulfite ions achieved depression effects on sphalerite through other non-adsorption ***,the oxygen content in the surface of sphalerite treated with sulfite ions in creased,which enhanced the hydrophilicity of the sphalerite and further increased the difference in hydrophilicity between sphalerite and ***,sulfite ions were chelated with lead ions to form PbSO_(3)in *** hydrophilic PbSO_(3)was more easily adsorbed on sphalerite than *** interaction between sulfite ions and lead ions could effectively inhibit the activation of *** addition the UV spectrum showed that after adding sulfite ions,the peak of perxanthate in the sphalerite treated xanthate solution was significantly stronger than that in the galena with xanthate solution,indicating that xanthate interacted more readily with sulfite ions and oxygen mo lecules within the sphalerite system,leading to the formation of ***,sulfite ions hardly depressed the flotation of ga lena and could promote the flotation of galena to some *** study deepened the understanding of the depression mechanism o sulfite ions on sphalerite and Pb^(2+)activated sphalerite.

关键词： sphalerite galena sulfite ion density functional theory depression mechanism

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Assessing the corrosion protection property of coatings loaded with corrosion inhibitors using the real-time atmospheric corrosion monitoring technique

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 119-126页

作者： Xiaoxue Wang Lulu Jin Jinke Wang Rongqiao Wang Xiuchun Liu Kai Gao Jingli sun yong Yuan Lingwei Ma Hongchang Qian Dawei Zhang School of Energy and Power Engineering Beihang UniversityBeijing 100191China Beijing Institute of Space Long March Vehicle Beijing 100076China National Materials Corrosion and Protection Data Center University of Science and Technology BeijingBeijing 100083China Institute of Materials Intelligent Technology Liaoning Academy of MaterialsShenyang 110004China Shanghai Spaceflight Precision Machinery Institute Shanghai 201600China

The atmospheric corrosion monitoring(ACM)technique has been widely employed to track the real-time corrosion behavior of metal ***,limited studies have applied ACM to the corrosion protection properties of organic *** study compared a bare epoxy coating with one containing zinc phosphate corrosion inhibitors,both applied on ACM sensors,to observe their corrosion protection properties over *** with artificial damage via scratches were exposed to immersion and alternating dry and wet environments,which allowed for monitoring galvanic corrosion currents in *** the corrosion tests,the ACM currents of the zinc phosphate/epoxy coating were considerably lower than those of the blank epoxy *** trend in ACM current variations closely matched the results obtained from regular electrochemical tests and surface *** alignment highlights the potential of the ACM technique in evaluating the corrosion protection capabilities of organic *** with the blank epoxy coating,the zinc phosphate/epoxy coating showed much-decreased ACM current values that confirmed the effective inhibition of zinc phosphate against steel corrosion beneath the damaged coating.

关键词： atmospheric corrosion monitoring technology corrosion inhibitor coating carbon steel corrosion protection

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Recent Advances in Fibrous Materials for Hydroelectricity Generation

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Nano-Micro Letters 2025年第2期17卷 109-133页

作者： Can Ge Duo Xu Xiao Feng Xing Yang Zheheng Song Yuhang Song Jingyu Chen Yingcun Liu Chong Gao yong Du Zhe sun Weilin Xu Jian Fang College of Textile and Clothing Engineering Soochow UniversitySuzhou 215123People’s Republic of China National Engineering Laboratory for Modern Silk Soochow UniversitySuzhou 215123People’s Republic of China State Key Laboratory of New Textile Materials and Advanced Processing Technologies Wuhan Textile UniversityWuhan 430200People’s Republic of China Institute of Functional Nano&Soft Materials(FUNSOM) Soochow UniversitySuzhou 215123People’s Republic of China Department of Electrical and Computer Engineering University of MassachusettsAmherstMA 01003USA Department of Materials Imperial College LondonSouth Kensington CampusLondon SW72AZUK College of Textile Science and Engineering Zhejiang Sci-Tech UniversityHangzhou 310018People’s Republic of China School of Materials Science and Engineering Shanghai Institute of Technology100 Haiquan RoadShanghai 201418People’s Republic of China

Depleting fossil energy sources and conventional polluting power generation pose a threat to sustainable *** generation from ubiquitous and spontaneous phase transitions between liquid and gaseous water has been considered a promising strategy for mitigating the energy *** materials with unique flexibility,processability,multifunctionality,and practicability have been widely applied for fibrous materials-based hydroelectricity generation(FHG).In this review,the power generation mechanisms,design principles,and electricity enhancement factors of FHG are first ***,the fabrication strategies and characteristics of varied constructions including 1D fiber,1D yarn,2D fabric,2D membrane,3D fibrous framework,and 3D fibrous gel are ***,the advanced functions of FHG during water harvesting,proton dissociation,ion separation,and charge accumulation processes are analyzed in ***,the potential applications including power supply,energy storage,electrical sensor,and information expression are also ***,some existing challenges are considered and prospects for future development are sincerely proposed.

关键词： Hydroelectricity Fibrous material Streaming potential Ion diffusion

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Optimal Sizing of Electricity-hydrogen Integrated Energy System Considering Multi-timescale Operation of Hydrogen Storage System

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Dianwang Jishu/Power System Technology 2025年第1期49卷 12-21页

作者： Li, Zichen Xia, Yanghong sun, yong Li, Dexin Li, Baoju Wei, Wei College of Electrical Engineering Zhejiang University Zhejiang Province Hangzhou 310027 China Institute of Wenzhou Zhejiang University Zhejiang Province Wenzhou 325006 China State Grid Jilin Electric Power Company Co. Ltd. Jilin Province Jilin 130021 China

Responding to the Carbon Peaking and Carbon Neutrality Goals and the actual demand for local consumption of distributed renewable energy sources, this paper proposes a method to optimize the capacity of an electricity-hydrogen integrated energy system to meet the demand for multiple loads of electricity, heat, and hydrogen to deal with multi-timescale energy mismatches. Firstly, a hybrid energy storage system model containing batteries and cascade hydrogen storage and a multi-timescale operation strategy are proposed. The model fully exploits the short-term and long-term operational characteristics of hydrogen storage to realize its multi-scale utilization. Secondly, to address the challenges in describing the operation characteristics of long-term energy storage devices based on the traditional typical scenario method, a novel scenario reduction method based on the time-series aggregation method is proposed to provide consecutive scenarios comprising both short-time fluctuations and seasonal characteristics. The technique can effectively speed up the solution and ensure its accuracy. After that, a system capacity optimization model is developed based on the typical scenarios to minimize the life cycle cost and consider factors including energy storage’s degradation and the consumption rate of renewable energy. Finally, the effectiveness of the proposed method is verified by cases in Ningbo, Zhejiang, China. The results indicate that the life cycle cost can be reduced by 21.3% with nearly 100% renewable energy consumption compared to the traditional energy management strategy. © 2025 Power System Technology Press. All rights reserved.

关键词： Charge storage

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Mutual regulation of microglia and astrocytes after Gas6 inhibits spinal cord injury

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Neural Regeneration Research 2025年第2期20卷 557-573页

作者： Jiewen Chen Xiaolin Zeng Le Wang Wenwu Zhang Gang Li Xing Cheng Peiqiang Su yong Wan Xiang Li Department of Spine Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Guangdong Province Key Laboratory of Orthopedics and Traumatology GuangzhouGuangdong ProvinceChina

Invasive inflammation and excessive scar formation are the main reasons for the difficulty in repairing nervous tissue after spinal cord *** and astrocytes play key roles in the spinal cord injury micro-environment and share a close ***,the mechanisms involved remain *** this study,we found that after spinal cord injury,resting microglia(M0)were polarized into pro-inflammatory phenotypes(MG1 and MG3),while resting astrocytes were polarized into reactive and scar-forming *** expression of growth arrest-specific 6(Gas6)and its receptor Axl were significantly down-regulated in microglia and astrocytes after spinal cord *** vitro experiments showed that Gas6 had negative effects on the polarization of reactive astrocytes and pro-inflammatory microglia,and even inhibited the cross-regulation between *** further demonstrated that Gas6 can inhibit the polarization of reactive astrocytes by suppressing the activation of the Yes-associated protein signaling ***,in turn,inhibited the polarization of pro-inflammatory microglia by suppressing the activation of the nuclear factor-κB/p65 and Janus kinase/signal transducer and activator of transcription signaling *** vivo experiments showed that Gas6 inhibited the polarization of pro-inflammatory microglia and reactive astrocytes in the injured spinal cord,thereby promoting tissue repair and motor function ***,Gas6 may play a role in the treatment of spinal cord *** can inhibit the inflammatory pathway of microglia and polarization of astrocytes,attenuate the interaction between microglia and astrocytes in the inflammatory microenvironment,and thereby alleviate local inflammation and reduce scar formation in the spinal cord.

关键词： astrocytes Axl cell polarization Gas6 Hippo signal inflammatory micro-environment intercellular interaction microglia single-cell sequencing spinal cord injury

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