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Journal of Iron and Steel Research International 2017年第4期24卷 435-441页

作者： Ying Bao Dong-ye Yang Na Liu Guo-qing Zhang Zhou Li Fu-yang Cao Jian-fei sun School of Materials Science and Engineering Harbin Institute of Technology School of Materials Science and Engineering Harbin University of Science and Technology Science and Technology on Advanced High Temperature Structural Materials Laboratory Beijing Institute of Aeronautical Materials

The hot compressive deformation behavior of hot isostatically pressed Ti-47.5Al-2Cr-2Nb-0.2W-0.2B alloy using gas atomization powders was systematically investigated and the processing map was obtained in the temperature range of 1323-1473 Kand strain rate range of 0.001-0.5s^（-1）.The calculated activation energy in the above variational ranges of temperature and strain rate possesses a low activation energy value of approximately 365.6kJ/mol based on the constitutive relationship models developed with the Arrhenius-type constitutive model respectively considering the strain rate and deformation *** hot working flow behavior during the deformation process was analyzed combined with the microstructural ***,the processing maps during the deformation process were established based on the dynamic material model and Prasad instability criterion under different deformation ***,the optimal hot processing window of this alloy corresponding to the wide temperature range of 1353-1453 Kand the low strain rate of 0.001-0.1s^（-1） was obtained.

关键词： Hot compressive deformation TiAl alloy Constitutive equation Processing map Gas atomization Hot isostatic pressing

Effects of topiramate versus other antiepileptic drugs on the cognitive function of patients with epilepsy

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Neural Regeneration Research 2007年第2期2卷 95-98页

作者： fei Xu Qionghua Feng Liang Yu Jie Liu Hongbin sun Department of Neurology Sichuan People＇s Hospital Sichuan Academy of Medical Science Chengdu 610072 Sichuan Province China Sichuan Society of Neurology Sichuan Institute of Medicine Chengdu 610072 Sichuan Province China

BACKGROUND： Only very large dose of topiramate has neurotoxicity, indicating that topiramate has low neurotoxicity and high safety. The residual rate of topiramate is affected by many cognitive-related adverse effects. Patients who take topiramate often accompany with thought slowness, difficulty in finding words, dyscalculia, blunt reaction, attention decreasing, memory deterioration, etc. OBJECTIVE： To compare the effects of topiramate with traditional anti-epileptic drugs （including carbamazepine and Valproic acid （VPA） on cognitive function of patients with epilepsy. DESIGN： Observational experiment, self-control and intergroup comparison. SETTING： Sichuan Academy of Medical Science. PARTICIPANTS： Eighty-seven inpatients and outpatients with newly diagnosed epilepsy who received preliminary diagnosis and follow-up in the Department of Neurology, Sichuan People＇s Hospital between January 2004 and June 2006 were involved in this survey. They were diagnosed according to disease history and electroencephalogram （EEG）. The onset type was diagnosed following the definition of epilepsy and epileptic syndrome in 1989 International Anti-epileptic League. The involved patients and their relatives were informed of detection and therapeutic regimen. The patients were assigned into two groups according to table of random digit： traditional antiepileptic drugs group （AEDs group, n =44） and topiramate （TPM） group （n =43）. METHODS：（1）Among the patients in AEDs group, carbamazepine was the first choice for 21 patients with partial seizures or partial secondarily generalized seizures, and VPA for 23 patients with generalized seizures. The initial dose of carbamazepine was 300 mg/d, and that of VPA was 500 mg/d. Patients in the TPM group took TPM with the initial dose of 25 mg/d, increased by 25 mg/d each week to target dose 150 mg/d within 8 weeks. （2） Curative effect was graded into 4 degrees： markedly effective, effective, ineffective and aggravated. Total effective rate was c

关键词： epilepsy cognition carbamazepine valproic acid

正畸目标管理对口腔正畸患者正畸效果、牙周健康、口腔保健效能的影响

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海南医学 2024年第17期35卷 2558-2562页

作者：彭怀芝孙倩张芳园崔淑霞郑州大学第一附属医院大学路口腔正畸科河南郑州450000 郑州大学第一附属医院大学路口腔修复科河南郑州450000

目的探讨正畸目标管理对口腔正畸患者正畸效果、牙周健康、口腔保健效能的影响。方法前瞻性选择2021年6月至2023年6月郑州大学第一附属医院收治的186例口腔正畸患者,按随机数表法分为目标管理组和常规干预组各93例。常规干预组患者接受... 详细信息

目的探讨正畸目标管理对口腔正畸患者正畸效果、牙周健康、口腔保健效能的影响。方法前瞻性选择2021年6月至2023年6月郑州大学第一附属医院收治的186例口腔正畸患者,按随机数表法分为目标管理组和常规干预组各93例。常规干预组患者接受常规口腔正畸宣教及护理干预,目标管理组患者接受正畸目标管理宣教及护理干预。干预6个月后,比较两组患者的正畸效果,以及干预前后的牙周健康指数、口腔保健自我效能量表(SESS)评分和情绪状态,同时比较两组患者的并发症发生情况。结果干预后,目标管理组患者的正畸总有效率为96.77%,明显高于常规干预组的89.25%,差异有统计学意义(P<0.05);干预后,目标管理组患者的龈沟出血指数、牙龈指数、菌斑指数、焦虑自评量表(SAS)、抑郁自评量表(SDS)评分分别为(0.33±0.10)分、(0.47±0.11)分、(0.42±0.13)分、(41.02±4.15)分、(37.52±5.14)分,明显低于常规干预组的(0.71±0.15)分、(0.86±0.21)分、(0.79±0.20)分、(47.93±4.93)分、(44.98±5.77)分,差异均有统计学意义(P<0.05);干预后,目标管理组患者的SESS评分为(71.22±1.25)分,明显高于常规干预组的(62.45±4.20)分,差异有统计学意义(P<0.05);目标管理组患者的并发症总发生率为6.45%,明显低于常规干预组的16.13%,差异有统计学意义(P<0.05)。结论正畸目标管理可提升口腔正畸患者的正畸总有效率,改善牙周健康,提升口腔保健效能,减轻负性情绪,预防并发症的发生。

关键词：口腔正畸正畸目标管理牙周健康指数口腔保健自我效能并发症

低中度近视儿童青少年周边视网膜离焦状态及其影响因素分析

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眼科新进展 2024年第10期44卷 808-813页

作者：张守宽刘千千彭庆生高洪莲孙昕姜俊张磊滨州医学院附属医院(第一临床医学院)眼科山东省滨州市256600 滨州沪滨爱尔眼科医院山东省滨州市256600 滨州医学院附属医院医学研究中心山东省滨州市256600

目的探讨低中度近视儿童青少年周边视网膜离焦状态及其影响因素。方法横断面研究。281例6~15周岁双眼近视儿童青少年纳入研究,仅选择右眼数据分析。进行睫状肌麻痹验光及眼轴长度(AL)、平均角膜曲率(AveK)测量后,按照等效球镜度(SE)分... 详细信息

目的探讨低中度近视儿童青少年周边视网膜离焦状态及其影响因素。方法横断面研究。281例6~15周岁双眼近视儿童青少年纳入研究,仅选择右眼数据分析。进行睫状肌麻痹验光及眼轴长度(AL)、平均角膜曲率(AveK)测量后,按照等效球镜度(SE)分为低度近视(LM)组(-3.00 D≤SE≤-0.50 D)和中度近视(MM)组(-6.00 D≤SE<-3.00 D);根据AL[AL1组(23.00 mm≤AL≤24.00 mm)]、AL2组(24.00 mm0.05)外,TRDV、RDV-30、RDV-45、RDV-15-30、RDV-30-45、RDV-45-53、RDV-S、RDV-I、RDV-N均显著正向增加(均为P<0.05)。根据AL和AveK分组比较结果显示,AL2组患者TRDV、RDV-30、RDV-45、RDV-15-30、RDV-30-45、RDV-45-53、RDV-S、RDV-I、RDV-N均显著高于AL1组(均为P<0.05);AL3组患者TRDV、RDV-30、RDV-45、RDV-15-30、RDV-30-45、RDV-45-53、RDV-S、RDV-N均显著高于AL2组和AL1组,RDV-I、RDV-T均显著高于AL1组(均为P<0.05);AveK1组患者TRDV、RDV-30、RDV-45、RDV-15-30、RDV-30-45、RDV-45-53、RDV-S、RDV-I均显著高于AveK2组(均为P<0.05)。相关性分析结果显示,TRDV、RDV-45、RDV-30-45、RDV-45-53、RDV-S、RDV-N与年龄和AL均存在正相关,与SE和AveK均存在负相关;RDV-30、RDV-15-30、RDV-I与AL均存在正相关,与SE、AveK均存在负相关;RDV-T仅与AL存在正相关;RDV-15与年龄、SE、AL、AveK均不存在相关性。多元线性回归分析结果显示,年龄是RDV-45-53、RDV-S的影响因素;AL是TRDV、RDV-30、RDV-45、RDV-15-30、RDV-30-45、RDV-45-53、RDV-S、RDV-T的影响因素;AveK是RDV-I的影响因素;SE对各范围RDV均不存在显著影响。结论低中度近视儿童青少年周边视网膜离焦已基本达到远视离焦状态,其中AL相对较短的患者远视离焦量最少。在年龄、SE、AL、AveK四种因素中,年龄、AL和AveK均能影响低中度近视儿童青少年周边视网膜离焦,而AL是最重要的影响因素。

关键词：近视周边视网膜离焦眼轴长度等效球镜度多光谱屈光地形图角膜曲率

“茶叶生物化学”一流课程建设改革的探究与思考

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教育教学论坛 2024年第28期 86-89页

作者：孙彬妹郑鹏张灵枝刘少群华南农业大学园艺学院广东广州510642

在新农科建设背景下,培养理论基础扎实、综合实践能力强的“新茶学”人才尤为重要。“茶叶生物化学”是茶学本科生的一门专业基础课程,其教学效果会对其他专业课程的学习有较深的影响,因而提升其课程教学质量十分关键。对“茶叶生物化... 详细信息

在新农科建设背景下,培养理论基础扎实、综合实践能力强的“新茶学”人才尤为重要。“茶叶生物化学”是茶学本科生的一门专业基础课程,其教学效果会对其他专业课程的学习有较深的影响,因而提升其课程教学质量十分关键。对“茶叶生物化学”课程的教学现状进行分析,并对该课程教学改革方法进行探讨与研究,提出科学的教学方案及实施办法,以期为其他高校提高“茶叶生物化学”课程教学成效和教学质量,优化教学体系,培养拥有爱农学农、懂农强农知识体系的茶学人才提供思考和参考。

关键词：茶叶生物化学教学改革思政元素

Comparison of larval performance and oviposition preference of Spodoptera frugiperda among three host plants:Potential risks to potato and tobacco crops

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Insect Science 2021年第3期28卷 602-610页

作者： Jing-fei Guo Meng-Di Zhang Zu-peng Gao Deng-Jie Wang Kang-Lai He Zhen-Ying Wang State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijingChina Engineering Research Center of Natural Enemy Insects/Institute of Biological Control Jilin Agricultural UniversityChangchunChina Mianyang Academy of Agricultural Sciences MianyangSichuan ProvinceChina

Fall armyworm(FAW),Spodoptera frugiperda(***),is a majorpolyphagous pest with the potential to seriously damage various crops.A better under-standing of FAW's performance on different hosts may help to predict which plants willbe attacked when the preferred host is absent,and facilitate the development of effectivepest management *** compared the larval performance of FAW fed on maizewith that of FAW fed on potato and tobacco,which are important crops in China,usingan age-stage two-sex life table and adult female oviposition preference *** experiments with potato,tobacco,or maize as the host,FAW reared on maize exhib-ited the strongest performance with shorter developmental time in thc larval stage,longerlongevity,and a higher reproductive rate in *** oviposited on maize in pref-erence to potato or *** with larvae fed on maize,those fed on potato andtobacco exhibited significantly lower survival,with only 31.61%and 8.13%developing tothe adult stage,*** life table parameters,including the mean generationtime(T),net reproductive rate(R^(0)),finite rate of increase(λ),and intrinsic rate of nat-ural increase(r)were negatively affected in FAW fed on potato and *** resultssupport the preference-performance hypothesis,that is,that herbivore females maximizefitness by choosing host plants associated with strong larval *** lar-vae and adults performed poorly on potato and tobacco,their offspring will be capable ofcstablishing populations on them,posing a potential threat to these crops in China.

关键词： fall armyworm host suitability maize potato tobacco

The discovery of new scaffold of plant activators：From salicylic acid to benzotriazole

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Chinese Chemical Letters 2017年第4期28卷 919-926页

作者： Kang Chang Jian-Qin Chen Yan-Xia Shi Mei-Jian sun peng-fei Li Zhen-Jiang Zhao Wei-Ping Zhu Hong-Lin Li Yu-Fang Xu Bao-Ju Li Xu-Hong Qian State Key Laboratory of Bioreactor Engineering Shanghai Key Laboratory of Chemical Biology School of Pharmacy East China University of Science and Technology Shanghai 200237 China State Key Laboratory of Bioreactor Engineering Shanghai Key Laboratory of New Drug Design School of Pharmacy East China University of Science and Technology Shanghai 200237 China Institute of Vegetables and Flowers Chinese Academy of AgricuRural Science Beijing 100081 China

Started from salicylic acid（SA） and related commercialized plant activators,based on molecular threedimensional shape and pharmacophore similarity comparison（SHAFTS）,a new lead compound benzotriazole was predicted and a series of benzotriazole derivatives were designed and *** bioassay showed that benzotriazole had high activity against a broad spectrum of diseases including fungi and oomycetes in vivo,but no activity in *** the introduction of proper groups at the1＇-position and 5＇-position was beneficial to the ***,they had the potential to be exploited as novel plant activators.

关键词： Plant activator Systemic acquired resistance Salicylic acid Benzotriazole Virtual screening

Grain yield and nitrogen use efficiency of an ultrashort-duration variety grown under different nitrogen and seeding rates in direct-seeded and double-season rice in Central China

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Journal of Integrative Agriculture 2023年第4期22卷 1009-1020页

作者： WANG Xin-yu YANG Guo-dong XU Le XIANG Hong-shun YANG Chen WANG fei peng Shao-bing National Key Laboratory of Crop Genetic Improvement/Hubei Hongshan Laboratory/Key Laboratory of Crop Ecophysiology and Farming System in the Middle Reaches of the Yangtze River Ministry of Agriculture and Rural Affairs/College of Plant Science and TechnologyHuazhong Agricultural UniversityWuhan 430070P.R.China

Nitrogen(N) and seeding rates are important factors affecting grain yield and N use efficiency(NUE) in directseeded rice. However, these factors have not been adequately investigated on direct-seeded and double-season rice(DDR) in Central China. The objective of this study was to evaluate the effects of various N and seeding rates on the grain yield and NUE of an ultrashort-duration variety grown under DDR. Field experiments were conducted in 2018 in Wuxue County and 2019 in Qichun County, Hubei Province, China with four N rates and three seeding *** results showed that the grain yield of the ultrashort-duration variety ranged from 6.32 to 8.23 t ha–1with a total growth duration of 85 to 97 days across all treatments with N application. Grain yield was increased significantly by N application in most cases, but seeding rate had an inconsistent effect on grain yield. Furthermore, the response of grain yield to the N rates was much higher than the response to seeding rates. The moderate N rates of 100–150 and 70–120 kg N ha–1in the early and late seasons, respectively, could fully express the yield potential of the ultrashort-duration variety grown under DDR. Remarkably higher N responses and agronomic NUE levels were achieved in the early-season rice compared with the late-season rice due to the difference in indigenous soil N supply capacity(INS) between the two seasons. Seasonal differences in INS and N response should be considered when crop management practices are optimized for achieving high grain yield and NUE in ultrashort-duration variety grown under DDR.

关键词： direct-seeded and double-season rice grain yield nitrogen rate nitrogen use efficiency seeding rate

Identification and Expression of PPAR in Sinonovacula constricta and Their Potential Regulatory Effects on Δ6 Fad Transcription

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Journal of Ocean University of China 2021年第6期20卷 1557-1566页

作者： RAN Zhaoshou KONG fei LIAO Kai XU Jilin LIU Xingwang SHI peng ZHANG Mengqi WU Kaibin YAN Xiaojun Key Laboratory of Applied Marine Biotechnology Ningbo UniversityMinistry of Education of ChinaNingbo 315211China Collaborative Innovation Center for Zhejiang Marine High-Efficiency and Healthy Aquaculture Ningbo UniversityNingbo 315211China Fujian Baozhi Aquatic Science and Technology Co. Ltd.Zhangzhou 363503China National and Local Joint Engineering Laboratory of Marine Biotechnology and Engineering Ningbo 315211China Key Laboratory of Marine Biological Engineering Ningbo 315211China Evergreen Feed Co. Ltd.Ningbo 315211China

Peroxisome proliferator activated receptors(PPAR)are kinds of key transcriptional factors in regulating LC-PUFA *** now,little is known about PPAR in marine molluscs as well as in other *** constricta is the first marine mollusc that is proved to possess the complete LC-PUFA biosynthetic pathway,and it can be a perfect representative to clarify this *** this study,the molecular properties of *** PPAR were characterized,and corresponding potential regulatory roles in ***Δ6 fatty acyl desaturase(Fad)transcription were estimated by dual luciferase *** showed that two PPAR homologs(PPAR_a and_b)were identified in *** both contain typical features of vertebrate PPAR,suggesting highly conserved functional regions in *** phylogenetic comparison,they are clearly different with vertebrate PPAR and can be divided into two distinctive ***,they show a high expression level in gill,labial palps,mantle and *** down-regulated expressions in trochophore larva and veliger larva might be attributed to ***,the transcriptional activity of ***Δ6 Fad promoter was significantly activated by both PPAR_a and_b,indicating that *** PPAR might play a role in the regulation of LC-PUFA *** our knowledge,this is the first systematic analysis of PPAR in a marine *** results will provide a valuable reference for further researches on the function of marine molluscan PPAR and their underlying mechanisms in regulating LC-PUFA biosynthesis.

关键词： Sinonovacula constricta peroxisome proliferator activated receptors Δ6 fatty acyl desaturase long chain-polyunsaturated fatty acids

An edible fruit from the Jurassic of China

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China Geology 2020年第1期3卷 8-15页

作者： Li-jun Chen Ye-mao Hou peng-fei Yin Xin Wang Shenzhen Key Laboratory for Orchid Conservation and Utilization National Orchid Conservation Center of China and Orchid Conservation&Research Center of ShenzhenShenzhen 518114China Key Laboratory of Vertebrate Evolution and Human Origin of Chinese Academy of Sciences Institute of Vertebrate Paleontology and Paleoanthropology and Center for Excellence in Life and PaleoenvironmentChinese Academy of SciencesBeijing 100044China State Key Laboratory of Palaeobiology and Stratigraphy Nanjing Institute of Geology and Palaeontology and Center for Excellence in Life and PaleoenvironmentChinese Academy of SciencesNanjing 210008China Department of Geology Northwest UniversityXi'an 710069China

Frugivory is an important ecological tie between animals and *** plays an important role in the evolution of food webs and energy flow networks in the ***,little is known about how old this relationship can be due to lack of relevant fossil ***,the authors report a fossil fruit,Jurafructus ***.,a putative angiosperm from the Middle-Late Jurassic(>164 Ma)of Daohugou Village,Inner Mongolia,China,which provides the currently earliest evidence of *** fossil is a more or less three-dimensionally preserved coalified drupe that has been damaged by animals in two different *** pericarp,in addition to the seed coat surrounding parenchyma seed contents,is suggestive of an angiospermous affinity,as such a 3+3 structure is distinct from a three-layered seed coat in *** seed possesses a distal micropyle,attached on the base of the pericarp,suggestive of a former orthotropous ovule in the *** damaged pericarp of Jurafructus suggests that firugivory can be dated back to the Middle-Late ***,the ecological relationship between angiosperms and animals extends deep into the fossil record.

关键词： Jurafructus Jurassic Angiosperm Evolution Animals Frugivory Fruit China