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井筒式超深基坑混凝土内支撑拆除施工技术

建筑技术 2024年第13期55卷 1599-1603页

作者：孙聪聪上海宝冶集团有限公司上海200441

随着地下空间的广泛应用,基坑向着“大”和“深”的方向发展,深基坑钢筋混凝土内支撑支护设计得到了广泛应用,且多处于城市中心的老城区及闹市区,周围建筑密集,施工现场综合环境复杂。以濮阳市老城区中医院内井筒式地下立体停车库超深... 详细信息

随着地下空间的广泛应用,基坑向着“大”和“深”的方向发展,深基坑钢筋混凝土内支撑支护设计得到了广泛应用,且多处于城市中心的老城区及闹市区,周围建筑密集,施工现场综合环境复杂。以濮阳市老城区中医院内井筒式地下立体停车库超深基坑混凝土内支撑拆除为例,介绍了井筒式超深基坑混凝土内支撑采用盘扣式架结合绳锯切割拆除的施工技术。实践证明,通过采用该技术,在确保深基坑安全的同时,满足了工期要求,该技术成熟可行,取得了良好的效果。

关键词：地下空间井筒式超深基坑混凝土内支撑

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CVC护理人员手卫生依从性与影响因素分析

中国城乡企业卫生 2024年第2期39卷 104-106页

作者：孙丛丛高唐县人民医院重症医学科山东聊城252800

目的探讨重症监护室(ICU)中心静脉导管(CVC)置管护理人员手卫生依从性和影响因素分析,为预防CVC感染提供参考。方法选取2019年5月—2020年12月高唐县人民医院ICU内CVC置管护理人员45例为研究对象,采用问卷调查的方式了解护理人员的手... 详细信息

目的探讨重症监护室(ICU)中心静脉导管(CVC)置管护理人员手卫生依从性和影响因素分析,为预防CVC感染提供参考。方法选取2019年5月—2020年12月高唐县人民医院ICU内CVC置管护理人员45例为研究对象,采用问卷调查的方式了解护理人员的手卫生依从性情况,分析影响其手卫生依从性的相关因素。结果年龄和学历的不同在手卫生依从性评分方面差异均无统计学意义(P>0.05);职称和CVC操作年限的不同在手卫生依从性评分方面差异均有统计学意义(P<0.05)。影响手卫生依从性的影响因素较多,其中排名前5的依次是忘记洗手占88.89%、缺乏对洗手和手消毒的认知占84.44%、认为戴手套可替代洗手占77.78%、认为手卫生与CVC感染关系不大占66.67%和管理层不重视洗手操作占62.22%。结论职称和CVC置管操作年限不同的护理人员手卫生依从性评分方面存在明显差异,而忘记洗手、缺乏对洗手和手消毒的认知是影响其依从性的主要因素,因此急需开展相关职业培训,强化CVC置管护理人员的手卫生观念,从而提高手卫生依从性,降低CVC感染的发生率。

关键词：重症监护室中心静脉导管护理人员手卫生依从性影响因素

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预见性护理在ICU重症患者中的应用

中国城乡企业卫生 2024年第1期39卷 106-108页

作者：孙丛丛冯真真高唐县人民医院重症医学科山东聊城252800 高唐县人民医院消化内科

目的总结预见性护理在重症监护室(ICU)重症护理中的应用效果,以减少ICU不良事件的发生。方法选择2019年6月—2020年6月高唐县人民医院诊疗的ICU患者68例,通过奇偶法分为对照组和观察组各34例,对照组采取基础护理措施,观察组采取预见性... 详细信息

目的总结预见性护理在重症监护室(ICU)重症护理中的应用效果,以减少ICU不良事件的发生。方法选择2019年6月—2020年6月高唐县人民医院诊疗的ICU患者68例,通过奇偶法分为对照组和观察组各34例,对照组采取基础护理措施,观察组采取预见性护理措施。比较两组干预后患者的住院时间、感染发生率、护理满意率及心理状况评分。结果观察组住院时间短于对照组;观察组感染发生率为2.94%,低于对照组的23.53%;观察组护理满意率为97.06%,高于对照组的61.76%,差异均有统计学意义(P<0.05)。观察组焦虑、抑郁评分低于对照组,差异均有统计学意义(P<0.05)。结论预见性护理在ICU重症护理中的应用效果明显,进一步抑制了ICU内的感染情况,降低了感染发生率,减少了不良事件的发生率,且提升了临床护理满意率,缓解患者的负性情绪,促进患者保持良好的心情积极接受诊疗,具有较高的临床应用价值。

关键词：预见性护理重症监护室重症护理应用效果

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早期护理对危重症患者获得性衰弱的影响

中国城乡企业卫生 2024年第1期39卷 19-21页

作者：万丽娟孙丛丛高唐县人民医院重症医学科山东聊城252800

目的探究危重症患者应用早期护理对获得性衰弱的影响,为危重症患者获得性衰弱的护理提供指导。方法选取2019年12月—2020年12月高唐县人民医院收治的74例危重症患者,按照随机数字表法分为研究组和对照组各37例。对照组实施常规护理,研... 详细信息

目的探究危重症患者应用早期护理对获得性衰弱的影响,为危重症患者获得性衰弱的护理提供指导。方法选取2019年12月—2020年12月高唐县人民医院收治的74例危重症患者,按照随机数字表法分为研究组和对照组各37例。对照组实施常规护理,研究组在对照组基础上实施早期护理。比较两组患者生活能力、肌力水平、生理及慢性健康水平、住院时间、获得性衰弱发生率及护理满意率。结果研究组Barthel指数(BI)和医学研究委员会(MRC)肌肉力量评分高于对照组,急性生理与慢性健康评分(APACHEⅡ)低于对照组,差异均有统计学意义(P<0.05)。研究组住院时间短于对照组,获得性衰弱发生率明显低于对照组,差异均有统计学意义(P<0.05)。研究组护理总满意率为97.30%,高于对照组的75.68%,差异有统计学意义(χ^(2)=7.4000,P<0.05)。结论针对危重症患者应用早期护理可有效降低获得性衰弱发生率,改善肌力水平,提高自理能力,缩短住院时间,值得临床应用推广。

关键词：早期护理危重症患者获得性衰弱

Navigating Epstein–Barr virus autoimmunity:role of NK cells and T cells in multiple sclerosis

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Signal Transduction and Targeted Therapy 2024年第3期9卷 833-835页

作者： Chu Xie cong sun Mu-Sheng Zeng State Key Laboratory of Oncology in South China Guangdong Provincial Clinical Research Center for CancerGuangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and TherapySun Yat-sen University Cancer CenterGuangzhouP.R.China

In a recent study published in Cell,Vietzen and colleagues discovered the novel role of natural killer(NK)cells and EBVspecific CD8+T cell response in controlling EBV-inducing autoimmune response and collectively def... 详细信息

关键词： Epstein sclerosis killer

A combined evaluation of the characteristics and antibiotic resistance induction potential of antibiotic wastewater during the treatment process

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Journal of Environmental Sciences 2024年第4期138卷 626-636页

作者： sun Miao Yanyan Zhang cong Men Yiou Mao Jiane Zuo State Key Joint Laboratory of Environment Simulation and Pollution Control School of EnvironmentTsinghua UniversityBeijing 100084China School of Energy and Environmental Engineering Beijing Key Laboratory of Resource-Oriented Treatment of Industrial PollutantsUniversity of Science and Technology BeijingBeijing 100083China High School Affiliated to Renmin University of China Beijing 100080China Tsinghua Shenzhen International Graduate School Shenzhen 518055China

Antibiotic wastewater contains a variety of pollutant stressors that can induce and promote antibiotic resistance(AR)when released into the *** these substances are mostly in concentrations lower than those known to induce AR individually,it is possible that antibiotic wastewater discharge might still promote the AR transmission risk via additive or synergistic ***,the comprehensive effect of antibiotic wastewater on AR development has rarely been evaluated,and its treatment efficiency remains ***,samples were collected from different stages of a cephalosporin production wastewater treatment plant,and the potential AR induction effect of their chemical mixtures was explored through the exposure of the antibiotic-sensitive Escherichia coli K12 *** with raw cephalosporin production wastewater significantly promoted mutation rates(3.6×10^(3)-9.3×10^(3)-fold)and minimum inhibition concentrations(6.0-6.7-fold)of *** against ampicillin and *** may be attributed to the inhibition effect and oxidative stress of cephalosporin wastewater on *** AR induction effect of cephalosporin wastewater decreased after the coagulation sedimentation treatment and was completely removed after the full treatment process.A Pearson correlation analysis revealed that the reduction in the AR induction effect had a strong positive correlation with the removal of organics and biological *** indicates that the antibiotic wastewater treatment had a collaborative processing effect of conventional pollutants,toxicity,and the AR induction *** study illustrates the potential AR transmission risk of antibiotic wastewater and highlights the need for its adequate treatment.

关键词： Antibiotic wastewater treatment plant Antibiotic resistance Antibiotic resistance induction effect Correlation analysis Biological toxicity

Review of GAN-Based Research on Chinese Character Font Generation

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Chinese Journal of Electronics 2024年第3期33卷 584-600页

作者： Xuanhong WANG cong LI Zengguo sun Luying HUI Xi'an University of Posts and Telecommunications School of Computer Science Shaanxi Normal University Key Laboratory of Intelligent Computing and Service Technology for Folk Song Ministry of Culture and Tourism

With the rapid development of deep learning,generative adversarial network(GAN) has become a research hotspot in the field of computer *** has a wide range of applications in image *** by GAN,a series of models of Chinese character font generation have been proposed in recent *** this paper,the latest research progress of Chinese character font generation is analyzed and *** and its development history are ***-based methods for Chinese character font generation are clarified as well as their improvements,based on whether the specific elements of Chinese characters are *** public datasets used for font generation are summarized in detail,and various application scenarios of font generation are *** evaluation metrics of font generation are systematically summarized from both qualitative and quantitative *** paper contributes to the in-depth research on Chinese character font generation and has a positive effect on the inheritance and development of Chinese culture with Chinese characters as its carrier.

关键词： Generative adversarial network Font generation Image-to-image translation Deep learning

Localization in modified polar representation: hybrid measurements and closed-form solution

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Journal of Systems Engineering and Electronics 2024年第3期35卷 575-588页

作者： cong Xunchao sun Yimao YANG Yanbing ZHANG Lei CHEN Liangyin The 10th Research Institute of China Electronics Technology Group Corporation Chengdu 610036China College of Computer Science and Institute for Industrial Internet Research Sichuan UniversityChengdu 610065China

Classical localization methods use Cartesian or Polar coordinates, which require a priori range information to determine whether to estimate position or to only find bearings. The modified polar representation (MPR) unifies near-field and farfield models, alleviating the thresholding effect. Current localization methods in MPR based on the angle of arrival (AOA) and time difference of arrival (TDOA) measurements resort to semidefinite relaxation (SDR) and Gauss-Newton iteration, which are computationally complex and face the possible diverge problem. This paper formulates a pseudo linear equation between the measurements and the unknown MPR position,which leads to a closed-form solution for the hybrid TDOA-AOA localization problem, namely hybrid constrained optimization(HCO). HCO attains Cramér-Rao bound (CRB)-level accuracy for mild Gaussian noise. Compared with the existing closed-form solutions for the hybrid TDOA-AOA case, HCO provides comparable performance to the hybrid generalized trust region subproblem (HGTRS) solution and is better than the hybrid successive unconstrained minimization (HSUM) solution in large noise region. Its computational complexity is lower than that of HGTRS. Simulations validate the performance of HCO achieves the CRB that the maximum likelihood estimator (MLE) attains if the noise is small, but the MLE deviates from CRB earlier.

关键词： localization modified polar representation time difference of arrival(TDOA) angle of arrival(AOA) closed-form solution

In Situ Deposition of Drug and Gene Nanoparticles on a Patterned Supramolecular Hydrogel to Construct a Directionally Osteochondral Plug

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Nano-Micro Letters 2024年第1期16卷 341-359页

作者： Jiawei Kang Yaping Li Yating Qin Zhongming Huang Yifan Wu Long sun cong Wang Wei Wang Gang Feng Yiying Qi Department of Orthopaedic Surgery The Second Affiliated HospitalZhejiang University School of MedicineHangzhou City 310009Zhejiang ProvincePeople’s Republic of China College of Chemical and Biological Engineering Zhejiang UniversityHangzhou 310027People’s Republic of China ZJU-Hangzhou Global Scientific and Technological Innovation Center Hangzhou 311215ZhejiangPeople’s Republic of China The Affiliated Nanhua Hospital Orthopedic Research CentreHengyang Medical SchoolUniversity of South ChinaHengyang 421001HunanPeople’s Republic of China Department of Radiology Jining No.1 People’s HospitalJining Medical UniversityJining 272000ShandongPeople’s Republic of China

The integrated repair of bone and cartilage boasts advantages for osteochondral restoration such as a long-term repair effect and less deterioration compared to repairing cartilage *** multifactorial,spatially oriented scaffolds to stimulate osteochondral regeneration,has immense ***,targeted drugs,namely kartogenin@polydopamine(KGN@PDA)nanoparticles for cartilage repair and miRNA@calcium phosphate(miRNA@CaP)NPs for bone regeneration,were in situ deposited on a patterned supramolecular-assembled 2-ureido-4[lH]-pyrimidinone(UPy)modified gelation hydrogel film,facilitated by the dynamic and responsive coordination and complexation of metal ions and their *** hydrogel film can be rolled into a cylindrical plug,mimicking the Haversian canal structure of natural *** resultant hydrogel demonstrates stable mechanical properties,a self-healing ability,a high capability for reactive oxygen species capture,and controlled release of KGN and *** vitro,KGN@PDA and miRNA@CaP promote chondrogenic and osteogenic differentiation of mesenchymal stem cells via the JNK/RUNX1 and GSK-3β/β-catenin pathways,*** vivo,the osteochondral plug exhibits optimal subchondral bone and cartilage regeneration,evidenced by a significant increase in glycosaminoglycan and collagen accumulation in specific zones,along with the successful integration of neocartilage with subchondral *** biomaterial delivery approach represents a significant toward improved osteochondral repair.

关键词： Osteochondral regeneration Oriented hydrogel Kartogenin miRNA-26a