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Marine Life Science & Technology 2021年第3期3卷 355-362页

作者： sukanta kumar nayak Pramod kumar Nanda Priyabrat Swain Department of Biotechnology Maharaja Sriram Chandra Bhanja Deo University(Erstwhile North Orissa University)Odisha757003India ICAR-Indian Veterinary Research Institute Eastern Regional StationKolkata700037India Fish Health Management Division Central Institute of Freshwater AquacultureBhubaneswar751002India

Antimicrobial proteins/peptides are becoming a new generation of immunostimulants for prevention and disease control in human and animals,including aquatic *** the haemolymph of horseshoe crabs(Tachypleus)contains broad ranges of bioactive compounds,we have explored the in vivo immunostimulating potential of amoebocyte lysate and plasma using a fish *** major carp,Labeo rohita,yearlings were injected intraperitoneally with two doses of lysate and plasma at 50 and 100µg protein per *** abnormalities and/or mortalities were recorded in any *** injected with 50µg lysate and 100µg plasma protein showed significant enhancement(P0.01)in any *** the contrary,a significantly high hemolysin titre was recorded in fish that received 100µg plasma *** challenge with Aeromonas hydrophila,both lysate and plasma protein(s)cross protected the fish after 30 *** highest survival(50%)was recorded in group injected with 50µg lysate protein,followed by 45%in both 100µg lysate and plasma protein injected groups.

关键词： Amoebocyte lysate Immunostimulatory Labeo rohita Plasma Tachypleus gigas

A review on edge analytics:Issues,challenges,opportunities,promises,future directions,and applications

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Digital Communications and Networks 2024年第3期10卷 783-804页

作者： Sabuzima nayak Ripon Patgiri Lilapati Waikhom Arif Ahmed National Institute of Technology Silchar India Ericsson Sweden

Edge technology aims to bring cloud resources(specifically,the computation,storage,and network)to the closed proximity of the edge devices,i.e.,smart devices where the data are produced and *** computing and application in edge devices lead to emerging of two new concepts in edge technology:edge computing and edge *** analytics uses some techniques or algorithms to analyse the data generated by the edge *** the emerging of edge analytics,the edge devices have become a complete ***,edge analytics is unable to provide full support to the analytic *** edge devices cannot execute advanced and sophisticated analytic algorithms following various constraints such as limited power supply,small memory size,limited resources,*** article aims to provide a detailed discussion on edge *** key contributions of the paper are as follows-a clear explanation to distinguish between the three concepts of edge technology:edge devices,edge computing,and edge analytics,along with their *** addition,the article discusses the implementation of edge analytics to solve many problems and applications in various areas such as retail,agriculture,industry,and ***,the research papers of the state-of-the-art edge analytics are rigorously reviewed in this article to explore the existing issues,emerging challenges,research opportunities and their directions,and applications.

关键词： Edge analytics Edge computing Edge devices Big data Sensor Artificial intelligence Machine learning Smart technology Healthcare

Identification of galectin-3 as a novel potential prognostic/predictive biomarker and therapeutic target for cerebral cavernous malformation disease

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Genes & Diseases 2024年第1期11卷 67-71页

作者： Souvik Kar Andrea Perrelli Kiran kumar Bali Raffaella Mastrocola Arpita Kar Bushra Khan Luis Gand Arnab nayak Christian Hartmann Wolfram SKunz Amir Samii Helmut Bertalanffy Saverio Francesco Retta International Neuroscience Institute Rudolf-PichlmayrStrasse 4Hannover 30625Germany Department of Clinical and Biological Sciences University of TorinoOrbassano(TO)10043Italy CCM Italia Research Network National Coordination Center at the Department of Clinical and Biological SciencesUniversity of TorinoOrbassano(TO)10043Italy Department of Experimental Pain Research Mannheim Center for Translational Neuroscience(MCTN)Medical Faculty MannheimHeidelberg UniversityMannheim 68167Germany Department of Kidney Liver and Metabolic DiseasesChildren’s HospitalHannover Medical SchoolHannover 30625Germany Ricarda-Huch-Street-10B Hannover 30880Germany Institute of Molecular and Cell Physiology Hannover Medical SchoolHannover 30625Germany Department of Neuropathology Institute of PathologyHannover Medical SchoolHannover 30625Germany Institute of Experimental Epileptology and Cognition Research and Department of Epileptology University Hospital BonnVenusberg-Campus 1Bonn 53127Germany epartment of Pharmacology and Physiology University of Rochester Medical CenterRochesterNY 14642USA

cerebrovascular disease of genetic origin characterized by abnormally dilated capillaries and a wide spectrum of symptoms,including headaches,seizures,neurological deficits,and intracerebral *** unpredictable clinical course and the current lack of therapies make the identification of prognostic and predictive biomarkers an imperative research challenge.1 Herein,we provide evidence that galectin-3(Gal-3),a major tissue and circulating biomarker of oxidative stress and inflammation,is significantly up-regulated both in CCM patients and ***,wholetranscriptome sequencing,qRT-PCR,and Western blotting studies demonstrated a significant up-regulation of Gal-3 expression levels both in surgical CCM specimens and in blood samples of CCM patients.

关键词： inflammation cerebral dilated

Biological,pathological,and multifaceted therapeutic functions of exosomes to target cancer

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Oncology Research 2024年第1期32卷 73-94页

作者： VIGNESH BALAJI E DIVYA RAMESH MANISHA CHUNGAN SHAJU AKSHARA kumar SAMYAK PANDEY RAKSHA nayak V.ALKA SRISHTI MUNJAL AMIR SALIMI K.SREEDHARA RANGANATH PAI SHANKAR M.BAKKANNAVAR Department of Pharmacology Manipal College of Pharmaceutical SciencesManipal Academy of Higher EducationManipalKarnataka576104India Department of Forensic Medicine and Toxicology Kasturba Medical CollegeManipal Academy of Higher EducationManipalKarnataka576104India School of Health and Community Services Durham CollegeOshawaOntarioL1G2G5Canada Department of Pharmaceutical Regulatory Affairs and Management Manipal College of Pharmaceutical SciencesManipal Academy of Higher EducationManipalKarnataka576104India Department of Clinical Psychology Manipal College of Health ProfessionsManipal Academy of Higher EducationManipalKarnataka576104India Department of Speech and Hearing Manipal College of Health ProfessionsManipal Academy of Higher EducationManipalKarnataka576104India Department of Pharmacy Practice Manipal College of Pharmaceutical SciencesManipal Academy of Higher EducationManipalKarnataka576104India

Exosomes,small tiny vesicle contains a large number of intracellular particles that employ to cause various diseases and prevent several pathological events as well in the human *** is considered a“double-edged sword”,and depending on its biological source,the action of exosomes varies under physiological ***,the isolation and characterization of the exosomes should be performed accurately and the methodology also will vary depending on the exosome ***,the uptake of exosomes from the recipients’cells is a vital and initial step for all the physiological *** are different mechanisms present in the exosomes’cellular uptake to deliver their cargo to acceptor *** the exosomal uptake takes place,it releases the intracellular particles that leads to activate the physiological *** though exosomes have lavish functions,there are some challenges associated with every step of their preparation to bring potential therapeutic ***,overcoming the pitfalls would give a desired quantity of exosomes with high purity.

关键词： Exosomes Physiology Cancer Therapeutics Challenges

Optimization of Wire-EDM Parameters for Ti-6Al-4V Using Taguchi-MRSN Optimization Approach

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Journal of Harbin Institute of Technology(New series) 2024年

作者： Ipsita nayak Jaydev Rana Department of Mechanical Engineering Veer Surendra Sai University of Technology

Ti-6Al-4V is a lightweight， extremely strong material with high resistance to corrosion and is widely used in aerospace industries， medical implants and many more. Contour cutting in such material with sharp corner radius， narrow kerf width， and maintaining high dimensional accuracy and surface integrity is a challenge for the modern manufacturing industry. Wire electrical discharge machining （WEDM） is a feasible process to meet the above challenges. However， proper control of process parameters is highly necessary for quality cutting of such material. In order to meet the above challenges， the present work focuses on the optimum selection of different process parameters such as pulse-on time (TON)， pulse-off time (TOFF)， spark gap voltage （SV） and wire feed rate （WF） using Taguchi-based multi response signal to noise ratio （MRSN） technique. This is a very simple multi response optimization technique to simultaneously optimize vital responses like thickness of white layer formed on the machined surfaces， average crack density， surface roughness and dimensional accuracy， without the assistance of any software. Moreover， simple regression models are developed to determine the above responses for any combination of process parameters. Industry personnel will find this study useful in utilizing this expensive non-conventional machining method in a techno-economic manner.

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Differential Power Based Selective Phase Tripping for Fault-resilient Microgrid

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Journal of Modern Power Systems and Clean Energy 2022年第2期10卷 459-470页

作者： Bhatraj Anudeep Paresh kumar nayak the Department of Electrical Engineering Indian Institute of Technology(ISM)DhanbadDhanbadIndia

Modern fault-resilient microgrids(MGs)require the operation of healthy phases during unbalanced short-circuits to improve the system *** study proposes a differential power based selective phase tripping scheme for MGs consisting of synchronous and inverter-interfaced distributed generators(DGs).First,the differential power is computed using the line-end superimposed voltage and current ***,to make the scheme threshold-free,a power coefficient index is derived and used for identifying faulted phases in an *** protection scheme is tested on a standard MG operating in either grid-connected or islanding mode,which is simulated using PSCAD/*** efficacy of the scheme is also assessed on the OPAL-RT manufactured real-time digital simulation(RTDS)***,the performance of the proposed protection scheme is compared with a few existing *** results show that the selective tripping of faulted phases in MGs can be achieved quickly and securely using the proposed scheme.

关键词： Distributed generator differential power fault detection microgrid protection selective phase tripping.

Deep Convolutional Network Based Machine Intelligence Model for Satellite Cloud Image Classification

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Big Data Mining and Analytics 2023年第1期6卷 32-43页

作者： Kalyan kumar Jena Sourav kumar Bhoi Soumya Ranjan nayak Ranjit Panigrahi Akash kumar Bhoi Department of Computer Science and Engineering Parala Maharaja Engineering CollegeBerhampur 761003India Amity School of Engineering and Technology Amity UniversityUttar Pradesh 201303India Department of Computer Applications Sikkim Manipal Institute of TechnologySikkim Manipal UniversitySikkim 737102India Directorate of Research Sikkim Manipal UniversityGangtokSikkim 737102India

As a huge number of satellites revolve around the earth,a great probability exists to observe and determine the change phenomena on the earth through the analysis of satellite images on a real-time ***,classifying satellite images plays strong assistance in remote sensing communities for predicting tropical *** this article,a classification approach is proposed using Deep Convolutional Neural Network(DCNN),comprising numerous layers,which extract the features through a downsampling process for classifying satellite cloud *** is trained marvelously on cloud images with an impressive amount of prediction *** time decreases for testing images,whereas prediction accuracy increases using an appropriate deep convolutional network with a huge number of training dataset *** satellite images are taken from the Meteorological&Oceanographic Satellite Data Archival Centre,the organization is responsible for availing satellite cloud images of India and its *** proposed cloud image classification shows 94% prediction accuracy with the DCNN framework.

关键词： satellite images satellite image classification cyclone prediction Deep Convolutional Neural Network(DCNN) features layers down-sampling process

Impact of Hierarchical Architecture of Cryptotermes brevis Wing on the Modulation of Bacterial Adhesion

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Journal of Bionic Engineering 2022年第2期19卷 516-529页

作者： Sanjeev kumar Paikra Sumit Mukherjee Nibedita nayak Janmejaya Bag Monalisa Mishra Neural Developmental Biology Laboratory Department of Life ScienceNational Institute of Technology769008RourkelaSundergarhOdishaIndia

The wing architecture is an inspiration to fabricate novel materials with exquisite *** current study characterizes the structure and biological function of a termite’s *** topography of the surface of the wing was studied by electron microscopy,and surface *** physicochemical property of the surface was analyzed by Fourier transform infrared spectroscopy,X-ray diffraction spectroscopy,energy-dispersive X-ray spectroscopy,and gas chromatography-mass spectrometry analysis of the epicuticle *** Contact Angle measurement confirmed the hydrophobicity of the wing *** microorganisms come in contact with the surface of the wing,they adhere to the wing surface due to cell surface properties of their own and the surface chemistry of the *** current study reported the adhesion behavior of two bacterial *** bactericidal activity of the wing was confirmed by counting the bacterial cell viability and examination under a confocal laser scanning *** of bacteria was observed under the electron *** oxidative stress,the topography of the wing,and the surface chemistry of the wing are the crucial factors that induce bactericidal *** nanostructure along with the chemical composition of the wing can be mimicked for the fabrication of novel material with antibacterial properties.

关键词： Bacterial adhesion Bactericidal Chitin Nanostructure Pseudomonas aeruginosa Staphylococcus aureus

Genetic Dissection of Grain Size Traits Through Genome-Wide Association Study Based on Genic Markers in Rice

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Rice science 2022年第5期29卷 462-472,I0032-I0034页

作者： Amrit kumar nayak Anilkumar C Sasmita BEHERA Rameswar Prasad SAH Gera Roopa LAVANYA Awadhesh kumar Lambodar BEHERA Muhammed Azharudheen TP Division of Crop Improvement Indian Council of Agricultural Research-National Rice Research InstituteCuttack 753006India Division of Crop Physiology and Biochemistry ICAR-National Rice Research InstituteCuttack 753006India Department of Genetics and Plant Breeding Sam Higginbottom University of AgricultureTechnology and SciencesPrayagraj 211007India

Grain size plays a significant role in rice,starting from affecting yield to consumer preference,which is the driving force for deep investigation and improvement of grain size *** inheritance makes these traits complex to breed on account of several alleles contributing to the complete trait *** employed genome-wide association study in an association panel of 88 rice genotypes using 142 new candidate gene based SSR(cgSSR)markers,derived from yield-related candidate genes,with the efficient mixed-model association coupled mixed linear model for dissecting complete genetic control of grain size traits.A total of 10 significant associations were identified for four grain size-related characters(grain weight,grain length,grain width,and length-width ratio).Among the identified associations,seven marker trait associations explain more than 10%of the phenotypic variation,indicating major putative QTLs for respective *** allelic variations at genes OsBC1L4,SHO1 and OsD2 showed association between 1000-grain weight and grain width,1000-grain weight and grain length,and grain width and length-width ratio,*** cgSSR markers,associated with corresponding traits,can be utilized for direct allelic selection,while other significantly associated cgSSRs may be utilized for allelic accumulation in the breeding programs or grain size *** new cgSSR markers associated with grain size related characters have a significant impact on practical plant breeding to increase the number of causative alleles for these traits through marker aided rice breeding programs.

关键词： best linear unbiased predictor estimate candidate gene based SSR efficient mixed-model association approach genome-wide association study VanRaden kinship

Dynamic viscoelastic behaviour,gelling properties of myofibrillar proteins and histological changes in shrimp(***)muscles during ice storage

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Aquaculture and Fisheries 2023年第2期8卷 180-189页

作者： Naresh kumar Mehta Banalata Rout Amjad KBalange Binaya Bhusan nayak Department of Fish Processing Technology and Engineering College of FisheriesCAU(I)LembucherraAgartalaTripura799210India Department of Post-Harvest Technology Central Institute of Fisheries EducationMumbai400061India

Changes in protein quality during ice storage affects the muscle structure,the textural quality,functional properties and the eating *** viscoelastic behaviour and gelling properties ofmeat proteinsin relation to histological changes in white leg shrimp muscles were assessed for 14 days in ice *** in Ca2+ATPase activity of fresh myofibrillar protein(MFP),fading of myosin banding pattern and increased gapping in myofibrils were clearly observed with progress of *** quality indices of the shrimp muscle were well correlated with histological and functional properties as a function of ice *** of fresh MFP was 86.76%which decreased to 77.06%on the 14th day of storage *** capacity found to increase during storage *** strength of white leg shrimp meat was low(81±14 g cm)and further,reduced nearly 60%compared to fresh sample at the end of *** considerable reductions(from 535.77 kPa to 246.56 kPa)in storage modulus values were evident of diminishing elasticity and gelling ability of the meat due to ice ***,this study usherd that the histological deterioration in myofibrils may be used as an indication of diminishing biochemical quality and gelling behaviour of the proteins.

关键词： White leg shrimp Myofibrillar proteins Quality Rheology Gel strength Functionality