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Global,regional and national burdens of bipolar disorders in adolescents and young adults:a trend analysis from 1990 to 2019

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General Psychiatry 2024年第1期37卷 122-132页

作者： Yunxi Zhong Yifan Chen Xiaoying su Meiqi Wang Qixiu Li Ziming Shao Long sun Centre for Health Management and Policy Research School of Public HealthCheeloo College of MedicineShandong UniversityJinanShandongChina National Health Commission of China(NHC)Key Laboratory of Health Economics and Policy Research Shandong UniversityJinanShandongChina nstitute of Health and Elderly Care Shandong UniversityJinanShandongChina

Background Bipolar disorder is identified as a cause of severe damage to the physical,psychological and social functioning of adolescents and young *** The aim of this study is to ascertain the trends in the burden of bipolar disorder among individuals aged 10-24 years at global,regional and national levels from 1990 to *** The data analysed in this study were from the Global Burden of Diseases *** numbers,rates per 100000 population,average annual percentage changes(AAPCs)of incidence,prevalence and years lived with disability(YLDs)of bipolar disorder are reported at the global,regional and national levels among individuals aged 10-24 *** trends by age,sex and Social Development Index(SDI)were further *** Globally,the incidence of bipolar disorder among adolescents and young adults increased from 79.21 per 100000 population(95%uncertainty interval(Ul):58.13 to 105.15)in 1990 to 84.97 per 100000 population(95%Ul:61.73 to 113.46)in 2019,AAPC 0.24(95%confidence interval(Cl):0.22 to 0.26).In the past three decades,there has been an increase in incidence,prevalence and YLDs in both males and *** largest increase in incidence between 1990 and 2019 was observed in those aged 20-24 years old from 51.76 per 100000 population(95%Ul:26.81 to 87.20)in 1990 to 58.37 per 100000 population(95%UI:30.39 to 98.55)in 2019;AAPC 0.42(95%Cl:0.38 to 0.47).By the SDI quintile,the largest increase in incidence was observed in the middle SDl;however,the high SDI countries had the highest ***,the largest increase in incidence was observed in southern Latin *** the national level,the most pronounced increase in the incidence was in *** The global increase in incidence among adolescents and young adults between 1990 and 2019 indicates that strategies to improve their mental health still need to be emphasised.

关键词： adolescent bipolar young

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Study on parameters of L-[1-^(13)C]phenylalanine breath test for quantitative assessment of liver function in healthy subjects and patients with hepatitis B virus-related liver disease

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Nuclear Science and Techniques 2005年第5期16卷 293-298页

作者： YAN Wei-Li LIN Xiang-Tong JIANG Yi-Bin sun su sun Da-Yu Department of Nuclear Medicine Department of Gastroenterology Huashan Hospital Fudan University Shanghai 200040

The aims of this study are to investigate the feasibility and validity of the L-[1-13C] phenylalanine breath test (13C-PheBT) which has been used to measure hepatocyte functional capacity in hepatitis B virus-related liver disease patients and to propose validity parameters of the test in 12 healthy volunteer, 8 chronic hepatitis and 26 liver cirrhotic patients. 100mg/body nonradiative L-[1-13C] phenylalanine (13C-Phe) was administered orally to all subjects. Breath samples were taken before and different intervals within 360 min after administration. The 13CO2/12CO2 en-richment was assessed by isotope ratio mass spectrometer. The parameter percentage 13C excretion rate 13CERt (% 13C dose/h) all peaked within 10-30 min after oral 13C-Phe application. The parameters such as maximum value of 13C excretion rate,13CERmax (% 13C dose/h) (controls: 18.0±3.3; Child A: 11.0±3.8; Child B: 5.0±0.5; Child C: 3.6±1.2), 13C excretion rate at 30min, 13CER30 (% dose/h) (controls: 11. 9±2.1; Child A: 8.1±0.4; Child B: 6.1±0.9; Child C: 3.2±1.2), 13C cumulative excretion of first 60 min, 13Ccum60 (% 13C dose) (controls: 9.3±1.4; Child A: 6.6±0.7; Child B: 4.1±0.3; Child C: 2.6±0.9) and half time of 13C excretion rate, T1/2 (minutes) (controls: 40.4±4.4; chronic hepatitis: 53.4±4.4; Child A: 59.8±4.5; Child B: 102.0±17.3; Child C: 212.1±87.9) were effective indexes which could be employed to stage hepatocyte impairment and liver functional reserve of advanced HBV-related cirrhotic patients (i.e. healthy subjects, Child A, B, C); T1/2 was also useful for distinguishing mild HBV-related liver injure.

关键词：肝硬化苯基丙氨酸肝炎呼吸方式放射性医学

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Defined organic-octamolybdate crystalline superstructures derived Mo_(2)C@C as efficient hydrogen evolution electrocatalysts

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Chinese Chemical Letters 2024年第6期35卷 201-205页

作者： Jiao Li Chenyang Zhang Chuhan Wu Yan Liu Xuejian Zhang Xiao Li Yongtao Li Jing sun Zhongmin su School of Materials Science and Engineering Jilin Jianzhu UniversityChangchun 130018China School of Chemical and Environmental Engineering Changchun University of Science and TechnologyChangchun 130022China

Hydrogen evolution electrocatalysts derived from metal-organic crystalline frameworks can inherit the merits of ordered and adjustable structures with high surface *** this paper,organic-octamolybdate crystalline superstructures(OOCS)with a fixed stoichiometric ratio of Mo_(8)(L)_(2) and high Mo content(>40 wt%)were synthesized using flexible ligands with controllable lengths(named as OOCS-1-3).Then,molybdenum carbides coated with carbon layers as electrocatalysts(Mo_(2)C@C-1-3)can be obtained directly from a one-step high-temperature carbonization process using OOCS-1-3 as *** a typical example,Mo_(2)C@C-3 exhibits satisfactory hydrogen evolution activity with a low overpotential of 151 m V(1.0 mol/L KOH)at 10 m A/cm^(2) and stability for 24 *** electrocatalytic activity is mainly from the synergistic interactions between the carbon layers and molybdenum carbide ***,compared with the initial content of C,N,Mo in OOCS and Mo_(2)C@C,the catalytic activity increases with the N *** work makes organic-octamolybdate crystalline superstructures used as general precursors to product high Mo content electrocatalysts applied in energy storage and conversion fields.

关键词： Molybdenum carbides Electrocatalysts Organic-octamolybdate crystalline superstructures Synergistic interactions Hydrogen evolution reaction(HER)

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Experimental Study on Gas Flow Uniformity in a Diesel Particulate Filter Carrier

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Fluid Dynamics & Materials Processing 2024年第1期20卷 193-204页

作者： Zhengyong Wang Jianhua Zhang Guoliang su Peixing Yang Xiantao Fan Shuzhan Bai Ke sun Guihua Wang School of Energy and Power Engineering Shandong UniversityJinan250061China State Key Laboratory of Engines Tianjin UniversityTianjin300072China Weichai Power Emission Solutions Technology Company Limited Weifang261043China China·Shandong·YYO Emission Control System Co. Ltd.Liaocheng252100China

A Diesel Particulate Filter(DPF)is a critical device for diesel engine exhaust products *** using active-regeneration purification methods,on the one hand,a spatially irregular gas flow can produce relatively high local temperatures,potentially resulting in damage to the carrier;On the other hand,the internal temperature field can also undergo significant changes contributing to increase this *** study explores the gas flow uniformity in a DPF carrier and the related temperature behavior under drop-to-idle(DTI)condition by means of bench *** is shown that the considered silicon carbide carrier exhibits good flow uniformity,with a temperature deviation of no more than 2%with respect to the same radius measurement point at the outlet during the regeneration *** the DTI test,the temperature is relatively high within r/2 near the outlet end,where the maximum temperature peak occurs,and the maximum radial temperature gradient is located between r/2 and the *** these quantities grow as the soot load increases,thereby making the risk of carrier burnout ***,it is shown that the soot load limit of the silicon carbide DPF can be extended to 11 g/L,which reduces the frequency of active regeneration by approximately 40%compared to a cordierite DPF.

关键词： DPF flow uniformity DTI silicon carbide carrier soot load

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Synergistic Effect of Nitrogen/Phosphorus Co-Doping and Molybdenum Carbide Induced Electron Redistribution of Carbon Layer to Boost Hydrogen Evolution Reaction

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Chinese Journal of Chemistry 2024年第1期42卷 55-60页

作者： Jiamin Xiao Peng Li Yanyan sun Heng Liu Javid Khan Handong Zhang Han Zhou Yaqiong su Shuangyin Wang Lei Han College of Materials Science and Engineering Hunan Joint International Laboratory of Advanced Materials and Technology for Clean EnergyHunan UniversityChangshaHunan 410082China School of Chemistry Engineering Research Center of Energy Storage Materials and Devices Ministry of EducationXi'an Key Laboratory of Sustainable Energy Materials ChemistryState Key Laboratory of Electrical Insulation and Power EquipmentXi'an Jiaotong UniversityXi'anShaanxi 710049China School of Materials Science and Engineering Central South UniversityChangshaHunan 410083China state Key Laboratory of Chem/Bio-Sensingand Chemometrics College of Chemistry and Chemical EngineeringHunan University ChangshaHunan 410082China Laboratory of Inorganic Materials and Catalysis Department of Chemical Engineering and ChemistryEindhoven University of Technology P.O.Box5135600 MB EindhovenThe Netherlands

The development of highly efficient non-precious-metal-based electrocatalysts for the hydrogen evolution reaction is imperative for promoting the large-scale application of electrochemical water ***,nitrogen/phosphorus co-doped carbon nanorods encapsulated Mo_(2)C nanoparticles(Mo_(2)C@PNc)have been prepared by pre-phosphating treatment in combination of the coordination with polydopamine and the subsequent *** phosphating temperature has a significant effect on the content of phosphorus within the resultant Mo_(2)C@PNC,and the optimal catalyst delivers superior HER activity with the low overpotential of 104 mV at a current density of 10 mAcm^(-2) and good stability for 8 h,which has been theoretically demonstrated to originate from the synergistic effect between P doping and Mo_(2)C induced electron redistribution of nitrogen-doped carbon layer.

关键词： Molybdenum carbide N/P co-doped carbon Hydrogen evolution Synergistic effect Electron redistribution Comprehensive

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Hierarchically Macroporous Zeolite ZSM-5 Microspheres for Efficient Catalysis

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Chemical Research in Chinese Universities 2024年第4期40卷 704-711页

作者： ZHENG Mingdan CHEN Ya LIU Zhan LYU Jiamin YE Bo sun Ming-Hui CHEN Li-Hua su Bao-Lian State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan430070P.R.China Laboratory of Inorganic Materials Chemistry(CMI) University of Namur5000NamurWalloniaBelgium

Hollow zeolite microspheres have recently attracted much attention for their applications in catalysis,microreactors and ***,we present hierarchically structured zeolite ZSM-5 microspheres with unique,abundant macropores that allow more efficient use for *** hierarchically macroporous zeolite ZSM-5 microspheres are synthesized under the assistance of water/oil emulsions and using polystyrene nanospheres as *** zeolite microsphere is assembled by uniform hollow zeolite *** large inner cavities and thin zeolite shells lead to smaller diffusion channel and higher improved accessibility to active sites,contributing to high catalytic performance in the catalytic conversion of benzyl alcohol in *** novel zeolite microspheres with impressive performance will be applied to numerous other industrial catalytic reactions.

关键词： Hierarchically porous structure Hollow structure Microsphere Zeolite ZSM-5 Alkylation

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A bacterial protein Rhp-PSP inhibits plant viral proliferation through endoribonuclease activity

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Journal of Integrative Agriculture 2024年第6期23卷 1967-1978页

作者： Lijie Chen Qianze Peng Xiaohua Du Weixing Zhang Ju’e Cheng Shu’e sun Deyong Zhang Pin su Yong Liu Longping Branch College of BiologyHunan UniversityChangsha 410082China State Key Laboratory of Hybrid Rice/Institute of Plant Protection Hunan Academy of Agricultural SciencesChangsha 410125China

Plant virus causes massive crop losses ***,there is currently no effective measure to control plant viral ***,we identify an antiviral protein Rhp-PSP,produced by the bacterial Rhodopseudomonas palustris strain *** this study,we discover that the antiviral activity of Rhp-PSP relies on its endoribonuclease *** the arginine(R)residue at position 129 onto alanine(A)abolishs its endoribonuclease activity on coat protein(CP)RNA of tobacco mosaic virus(TMV),consequentially,compromises the antiviral activity of *** investigation demonstrates that,the mutant Rhp-PSP^(R129A)is unable to form the homotrimer as the wild type,indicating the importance of quaternary junction for the endoribonuclease *** of Rhp-PSP in Nicotiana benthamiana significantly enhances the resistance against TMV of seedlings,while expression of Rhp-PSP^(R129A)did not,confirming that endoribonuclease activity is responsible for the antiviral activity of *** addition,foliar spray of Rhp-PSP solution on tomato and pepper plants significantly reduces the disease index of viral diseases,indicating that Rhp-PSP shows potential to develop antiviral agent in practice.

关键词： Rhodopseudomonas palustris Rhp-PSP tobacco mosaic virus endoribonuclease antiviral activity

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Incorporating metal nanoparticles in porous materials via selective heating effect using microwave

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Nano Research 2024年第4期17卷 3175-3179页

作者： Yingyu Zhou Jiacheng Liu Fuyuan sun Junchen Ouyang Ruifa su Fanchen Meng Yongqi Luo Cheng Xu Weina Zhang suoying Zhang Fengwei Huo Key Laboratory of Flexible Electronics(KLOFE)&Institute of Advanced Materials(IAM) Nanjing Tech UniversityNanjing 211816China

Metal nanoparticle@porous material composites have attracted increasing attention due to their excellent synergistic catalytic ***,it is a challenge to introduce metal nanoparticles into cavities of porous materials without agglomeration on the *** the progress achieved,a universal approach that can integrate different kinds of metal nanoparticles and porous materials is still highly *** we report a facile and general approach to fabricating metal nanoparticle@porous materials by microwave-triggered selective *** microwave can pass through the non-polar solvent and act on the polar solvent in the porous materials,causing the polar solvent to be heated,vaporized,and away from the pores of porous *** local void produced by the escape of polar solvent facilitates non-polar solvent containing metallic precursor to be dragged into the narrow pores,followed by further reduction,resulting in the complete encapsulation of nanoparticles.A series of metal nanoparticles@porous materials,ranging from metal-organic frameworks(MOFs)to zeolites,are successfully prepared by this method and show excellent size selectivity in catalytic reactions.

关键词： porous material nanoparticle encapsulation microwave synthesis selective heating effect selective catalysis

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认知性访谈在过渡期炎症性肠病患者过渡准备量表文化调适中的应用

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护理学报 2024年第6期31卷 1-5页

作者：孙素亚陈亚梅陈伟仙薄瑾刘晓红黄燕林梦月复旦大学附属华山医院宝山院区消化科上海201907 同济大学医学院上海200092 同济大学附属第十人民医院护理部上海200072 安徽中医药大学医学院安徽合肥230012

目的应用认知性访谈探讨过渡期炎症性肠病患者过渡准备量表(Transition Readiness Measure,TRM)的认知与领悟,就中文版过渡准备量表中的语义等内容再次进行测试。方法采用目的抽样法,选取上海市2所三级甲等医院就诊的18例处于过渡期... 详细信息

目的应用认知性访谈探讨过渡期炎症性肠病患者过渡准备量表(Transition Readiness Measure,TRM)的认知与领悟,就中文版过渡准备量表中的语义等内容再次进行测试。方法采用目的抽样法,选取上海市2所三级甲等医院就诊的18例处于过渡期的炎症性肠病患者,共开展3轮认知性访谈,了解其对中文版过渡准备量表初稿的认知,并结合专家小组意见,对存在歧义的条目进行修订,形成中文版过渡准备量表。结果第1轮访谈结果表明,部分受访者对中文版过渡准备量表中的4个条目的表达和理解有歧义;第2轮访谈结果表明,2例受访者对其中1个条目的表达和理解有歧义;第3轮访谈结果表明,受访者均能正确地理解修订后的各个条目,保持与源量表语义的一致性。结论认知性访谈基于患者视角进一步修订量表,促进受访者对中文版量表内容理解的一致性,有助于提高量表的科学性、适用性和准确性。

关键词：认知性访谈过渡期过渡准备炎症性肠病文化调适

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水厂黄水治理研究

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广州化工 2024年第12期52卷 119-121页

作者：张孝忠郝玉平张瑶孙粟张士宝李松霖郝梦雅徐州市水利建筑设计研究院有限公司江苏徐州221000 徐州市南水北调工程管理中心江苏徐州221000 徐州市水利工程运行管理中心江苏徐州221000

针对饮用水用户投诉的黄水问题,浙江某水厂从自身角度出发,拟从源头降低锰含量,积极寻找水源锰的去除方案。经过多次实验室小试试验及中试试验,结合水厂具体实际,对多种工艺进行优选,最终确定采用高锰酸钾和次氯酸钠联用工艺。具体投加... 详细信息

针对饮用水用户投诉的黄水问题,浙江某水厂从自身角度出发,拟从源头降低锰含量,积极寻找水源锰的去除方案。经过多次实验室小试试验及中试试验,结合水厂具体实际,对多种工艺进行优选,最终确定采用高锰酸钾和次氯酸钠联用工艺。具体投加方式为高锰酸钾投加浓度约为原水锰浓度的1.5倍,次钠投加量在20~25 mg/L,此时具备较好的水处理效果,可以将锰浓度控制在5 ppb以下,解决了用户黄水问题。

关键词：黄水锰高锰酸钾和次氯酸钠联用

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