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A marathon,not a sprint:Increasing population physical activity as a legacy of sports mega-events

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journal of Sport and Health Science 2024年第6期13卷 732-735页

作者： Fiona C.Bull Paul j.simpson Physical Activity Unit Department of Health PromotionWorld Health OrganizationGeneva CH-1211Switzerland The BMj London WC1H 9JPUK

*** matters The withdrawal of Australia as hosts for the Commonwealth Games in 2026 demonstrates that large international sporting events are more than just sporting mastery,medals,and *** also matters.1 The cost of hosting a major international tournament is eye-wateringly *** governments need to show that the billions of dollars of investment deliver a return beyond sporting glory to justify the resources that are spent.

关键词： return dollar sport

COVID-19 vaccination produces exercise-responsive SARS-CoV-2 specific T-cells regardless of infection history

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journal of Sport and Health Science 2024年第1期13卷 99-107页

作者： Kyle A.Smith Tiffany M.Zúñiga Forrest L.Baker Helena Batatinha Charles R.Pedlar Shane C.Burgess Michael P.Gustafson Emmanuel Katsanis Richard j.simpson School of Nutritional Sciences and Wellness The University of ArizonaTucsonAZ 85721USA Department of Pediatrics The University of ArizonaTucsonAZ 85724USA Faculty of Sport Allied Health and Performance ScienceSt.Mary's UniversityTwickenham TW14SXUK Institute of Sport Exercise and Health University College LondonLondon WC1E 7HUUK Department of Animal and Comparative Biomedical Sciences The University of ArizonaTucsonAZ 85721USA The University of Arizona Cancer Center The University of ArizonaTucsonAZ 85719USA Laboratory Medicine and Pathology Mayo Clinic ArizonaPhoenixAZ 85054USA Department of Immunobiology The University of ArizonaTucsonAZ 85724USA Department of Medicine The University of ArizonaTucsonAZ 85724USA Department of Pathology The University of ArizonaTucsonAZ 85724USA

Background:The mobilization and redistribution of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)specific T-cells and neutralizing antibodies(nAbs)during exercise is purported to increase immune surveillance and protect against severe coronavirus disease 2019(COVID-19).We sought to determine if COVID-19 vaccination would elicit exercise-responsive SARS-CoV-2 T-cells and transiently alter nAb ***:Eighteen healthy participants completed a 20-min bout of graded cycling exercise before and/or after receiving a COVID-19 *** major leukocyte subtypes were enumerated before,during,and after exercise by flow cytometry,and immune responses to SARS-CoV-2 were determined using whole blood peptide stimulation assays,T-cell receptor(TCR)-βsequencing,and SARS-CoV-2 nAb ***:COVID-19 vaccination had no effect on the mobilization or egress of major leukocyte subsets in response to intensity-controlled graded ***,non-infected participants had a significantly reduced mobilization of CD4+and CD8+naive T-cells,as well as CD4+central memory T-cells,after vaccination(synthetic immunity group);this was not seen after vaccination in those with prior SARS-CoV-2 infection(hybrid immunity group).Acute exercise after vaccination robustly mobilized SARS-CoV-2 specific T-cells to blood in an intensity-dependent *** groups mobilized T-cells that reacted to spike protein;however,only the hybrid immunity group mobilized T-cells that reacted to membrane and nucleocapsid *** increased significantly during exercise only in the hybrid immunity ***:These data indicate that acute exercise mobilizes SARS-CoV-2 specific T-cells that recognize spike protein and increases the redistribution of nAbs in individuals with hybrid immunity.

关键词： Anti-viral COVID-19 Exercise immunology SARS-CoV-2 T-Cells Vaccine

Low-protein diet accelerates wound healing in mice post-acute injury

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Burns & Trauma 2021年第1期9卷 339-350页

作者： jonathan j.Hew Roxanne j.Parungao Craig P.Mooney julian K.Smyth Sarah Kim Kevin H.-Y.Tsai Huaikai Shi Cassandra Chong Renee C.F.Chan Beba Attia Caroline Nicholls Zhe Li Samantha M.Solon-Biet David G.Le Couteur stephen j.simpson Marc G.jeschke Peter K.Maitz Yiwei Wang Burns Research and Reconstructive Surgery ANZAC Research InstituteConcord HospitalUniversity of SydneySydneyAustralia 2139 Bone Biology Group ANZAC Research InstituteConcord HospitalUniversity of SydneySydneyAustralia 2139 Adrenal Steroids Laboratory ANZAC Research InstituteConcord HospitalUniversity of SydneySydneyAustralia 2139 Electron Microscopy Unit Anatomical PathologyConcord HospitalSydneyAustralia 2139 Burns Unit Concord Repatriation General HospitalConcordAustralia 2139 Ageing and Alzheimer Institute and ANZAC Research Institute Concord HospitalUniversity of SydneySydneyAustralia 2139 Charles Perkins Centre and School of Life and Environmental Sciences University of SydneyAustralia 2006 Sunnybrook Research Institute TorontoOntarioCanadaM4N 3M5 School of Pharmacy Nanjing University of Chinese MedicineNanjingPR China 210023

Background:Wound healing processes are influenced by macronutrient intake(protein,carbohydrate and fat).The most favourable diet for cutaneous wound healing is not known,although highprotein diets are currently favoured *** experimental study investigates the optimal macronutrient balance for cutaneous wound healing using a mouse model and the Geometric Framework,a nutrient modelling method,capable of analyzing the individual and interactive effects of a wide spectrum of macronutrient ***:Two adjacent and identical full-thickness skin excisions(1 cm^(2))were surgically created on the dorsal area of male C57BL/6 *** were then allocated to one of 12 high-energy diets that varied in protein,carbohydrate and fat *** select diets,wound healing processes,cytokine expression,energy expenditure,body composition,muscle and fat reserves were ***:Using the Geometric Framework,we show that a low-protein intake,coupled with a balanced intake of carbohydrate and fat is optimal for wound *** fed a low-protein diet progressed quickly through wound healing stages with favourable wound inflammatory cytokine expression and significantly accelerated collagen *** local processes were associated with an increased early systemic inflammatory response and a higher overall energy expenditure,related to metabolic changes occurring in key macronutrient reserves in lean body mass and fat ***:The results suggest that a low-protein diet may have a greater potential to accelerate wound healing than the current clinically used high-protein diets.

关键词： Wound healing Macronutrients Cutaneous Geometric Framework Mouse model Low-protein diet Nutrition

Modern Corrosion Mapping of Storage Tank Bottoms--Notable Advancements in Critical Zone Coverage,Inspection Efficiency and Data Integrity

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journal of Civil Engineering and Architecture 2024年第3期18卷 148-153页

作者： Andrew j.simpson Matthew A.Boat Eddyfi Technologies-Eddyfi UK Ltd Clos Llyn CwmSwansea Enterprise ParkSwanseaSA68QYUK

Every day,an NDT(Non-Destructive Testing)report will govern key decisions and inform inspection strategies that could affect the flow of millions of dollars which ultimately affects local environments and potential risk to *** is a direct correlation between report quality and equipment *** more able the equipment is-in terms of efficient data gathering,signal to noise ratio,positioning,and coverage-the more actionable the report *** results in optimal maintenance and repair strategies providing the report is clear and well ***,when considering tank floor storage inspection it is essential that asset owners have total confidence in inspection findings and the ensuing *** floor inspection equipment must not only be efficient and highly capable,but data sets should be traceable and integrity maintained *** mapping of large surface areas such as storage tank bottoms is an inherently arduous and time-consuming ***(magnetic flux leakage)based tank bottom scanners present a well-established and highly rated method for *** are many benefits of using modern MFL technology to generate actionable *** among these includes efficiency of coverage while gaining valuable information regarding defect location,severity,surface origin and the extent of *** recent advancements in modern MFL tank bottom scanners afford the ability to scan and record data sets at areas of the tank bottom which were previously classed as dead zones or areas not scanned due to physical *** example of this includes scanning the CZ(critical zone)which is the area close to the annular to shell junction *** of these additional dead zones increases overall inspection coverage,quality and *** of the CZ areas allows engineers to quickly determine the integrity of arguably the most important area of the tank *** we discuss notable developments in CZ coverage

关键词： Storage tank tank bottom CZ MFL stars corrosion corrosion-mapping efficiency coverage paperless reporting data traceability

Distinct vibrational signatures and complex phase behavior in metallic oxygen

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Matter and Radiation at Extremes 2024年第2期9卷 4-11页

作者： Philip Dalladay-simpson Bartomeu Monserrat Li Zhang Federico Gorelli Center for High Pressure Science Technology Advanced Research 1690 Cailun RoadShanghai 201203China Department of Materials Science and Metallurgy University of Cambridge27 Charles Babbage RoadCambridge CB3 OFSUnited Kingdom Cavendish Laboratory University of CambridgeJ.J.Thomson AvenueCambridge CB3 OHEUnited Kingdom Istituto Nazionale di Ottica Consiglio Nazionale delle Ricerche(CNR-INO)50125 FlorenceItaly Shanghai Advanced Research in Physical Sciences(SHARPS) ShanghaiChina

Evidence for metallization in dense oxygen has been reported for over 30 years[Desgreniers et al.,***.94,1117(1990)]at a now routinely accessible 95 GPa[Shimizu et al.,Nature 393,767(1998)].However,despite the longevity of this result and the technological advances since,the nature of the metallic phase remains poorly constrained[Akahama et al.,***.74,4690(1995);Goncharov et al.,***.B 68,224108(2003);Ma,***.B 76,064101(2007);and Weck et al.,***.102,255503(2009)].In this work,through Raman spectroscopy,we report the distinct vibrational characteristics of metallicζ-O_(2) from 85 to 225 *** comparison with numerical simulations,weﬁnd reasonable agreement with the candidate structure up to about 150 *** higher pressures,the C2/mstructure is found to be unstable and incompatible with experimental *** candidate structures,and Ci,with C2/m C2/conly two molecules in the primitive unit cell,are found to be stable and more compatible with measurements above 175 GPa,indicative of the dissociation of(O_(2))4 ***,we report and discuss a strong hysteresis and metastability with the precursory phaseϵ-O_(2).Theseﬁndings will reinvigorate experimental and theoretical work into the dense oxygen system,which will have importance for oxygen-bearing chemistry,prevalent in the deep Earth,as well as fundamental physics.

关键词： metallic phase vibrational

Biomechanics of ankle giving way:A case report of accidental ankle giving way during the drop landing test

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journal of Sport and Health Science 2019年第5期8卷 494-502页

作者： Yumeng Li jupil Ko Shuqi Zhang Cathleen N.Brown Kathy j.simpson Department of Kinesiology California State UniversityChicoCA 95928USA Department of Physical Therapy and Athletic Training Northern Arizona UniversityPhoenixAZ 85004USA Department of Kinesiology and Physical Education Northern Illinois UniversityDeKalbIL 60115USA Department of Athletic Training and Kinesiology Oregon State UniversityCorvallisOR 97331USA Department of Kinesiology University of GeorgiaAthensGA 30602USA

Background:Several case studies observed that the lateral ankle sprain resulted from a sudden increase in ankle inversion accompanied by internal ***,without sufficient ankle kinetics and muscle activity information in the literature,the detailed mechanism of ankle sprain is still *** purpose of our case report is to present 2 accidental ankle giving way incidents for participants with chronic ankle instability(CAI)and compare to their normal trials with data of kinematics,kinetics,and electromyography(EMG).Case description:Two young female participants accidentally experienced the ankle giving way when landing on a 25°lateral-tilted force plate.3 D kinematics,kinetics,and muscle activity were recorded for the lower *** comparisons were made between the giving way trials and normal trials for joint angles,angular velocities,moments,centers of pressure and EMG linear ***:One participant’s giving way trial displayed increased ankle inversion and internal rotation angles in the pre-landing phase and at initial contact compared to her normal *** participant’s giving way trial exhibited greater hip abduction angles and delayed activation of the peroneus longus muscle in the pre-landing phase versus her normal ***:A vulnerable ankle position(i.e.,more inverted and internally rotated),and a late activation of peroneus activity in the pre-landing phase could result in the ankle giving way or even sprains.A neutral ankle position and early activation of ankle evertors before landing may be helpful in preventing ankle sprains.

关键词： Chronic ankle instability EMG Kinematics Kinetics Lateral anlde sprain

Cross-cultural adaptation and validation of an ankle instability questionnaire for use in Chinese-speaking population

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journal of Sport and Health Science 2019年第6期8卷 555-560页

作者： Yumeng Li Li Guan jupil Ko Shuqi Zhang Cathleen N.Brown Kathy j.simpson Department of Kinesiology California State University ChicoChicoCA 95926USA Department of Psychology University of GeorgiaAthensGA 30605USA Department of Physical Therapy and Athletic Training Northern Arizona UniversityFlagstaffAZ 86011USA Department of Kinesiology and Physical Education Northern Illinois UniversityDekalbIL 60115USA Department of Athletic Training and Kinesiology Oregon State UniversityCorvallisOR 97331USA Department of Kinesiology University of GeorgiaAthensGA 30605USA

Background:The Identification of Functional Ankle Instability(IdFAI)is a valid and reliable tool to identify chronic ankle instability;however,it was developed in English,thus limiting its usage only to those who can read and write in *** objectives of our study were to(1)cross-culturally adapt a Chinese(Mandarin)version of the IdFAI and(2)determine the psychometric properties of the Chinese version ***:The cross-cultural adaptation procedures used by the investigators and translators followed previously published guidelines and included 6 stages:(1)initial translation,(2)synthesis of the translations,(3)back translation,(4)developing the pre-final version for field testing,(5)testing the pre-final version,and(6)finalizing the Chinese version of IdFAI(IdFAI-C).Five psychometric properties of the IdFAI-C were assessed from results of 2 participant groups:bilingual(n=20)and Chinese(n=625).Results:A high degree of agreement was found between the English version of IdFAI and IdFAI-C(intra-class correlation_(2,1)=0.995).An excellent internal consistency(Cronbach'sα=0.89),test—retest reliability(intra-class correlation_(2,1)=0.970),and construct validity(r(625)=0.67)was also found for the *** addition,the results of exploratory and confirmatory factor analysis indicated that ankle instability was the only construct measured from the ***:The IdFAI-C is a highly reliable and valid self-report questionnaire that can be used to assess ankle ***,we suggest that it can be used to effectively and accurately assess chronic ankle instability in clinical settings for Chinese-speaking individuals.

关键词： Ankle giving way Ankle sprain Chronic ankle instability Identification of functional instability Mandarin Translation

Comparison of the‘Seattle’and‘International’Criteria Electrocardiogram Interpretation in Division II Female Collegiate Athletes:A Preliminary Study

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journal of Science in Sport and Exercise 2023年第3期5卷 274-279页

作者： Ludmila Cosio-Lima N.Kumar Brooke L.Adlof j.simpson A.Crawley Y.Lee University of West Florida 11000 University Parkway#72/220PensacolaFL 32514USA

Purpose A 12-lead electrocardiogram(ECG)is a screening tool to detect abnormalities that may predispose athletes to sud-den cardiac *** standardized criteria have been introduced to better interpret ECG data,however this research has predominantly focused on male *** is important to include female athletes in research to better define ECG character-istics in this *** purpose of this study was to compare the Seattle and International Criteria ECG abnormalities in Division II female collegiate athletes of various *** Fifty-six females(age 20.2±1.4 years;height 1.70±0.7 m;weight 69.5±8.9 kg)completed a resting 12-lead ECG *** data was classified as‘normal’and‘abnormal’according to the parameters of each criterion and abnormal conditions were ***-square analysis was used to assess statistical comparisons between *** There was a significant difference in abnormal classifications as the total number of ECGs identified as abnormal using the Seattle Criteria decreased from 12(21.4%)to 2(3.6%)when using the International Criteria(P<0.05).African American athletes had a higher number of abnormal ECG’s compared to White and Latina athletes using the Seattle Criteria(P=0.03).Conclusions The International Criteria significantly reduces the total number of abnormal ECG readings in female collegiate athletes compared to the Seattle Criteria and did not overly identify African American athletes with *** research is necessary to expand on this study and clearly define criteria for female athletes of various ethnicities.

关键词： 12-lead ECG Female athletes Sudden cardiac death ECG abnormalities

一次梳理及二次梳理对精梳落棉和纱线品质的影响

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国外纺织技术(纺织分册) 1985年第7期 14-17页

作者： j.simpson 钟毅芸

引言 1967年发表的一项研究结果表明,当梳棉产量增加时,梳棉网中的后弯钩大量减少,这样就改善了纤维的伸直平行度,降低了精梳过程中的落棉。落棉量少的精梳棉条中的纤维长度分布与落棉量多的精梳棉条中的纤维长度分布几乎相差无几。为此... 详细信息

引言 1967年发表的一项研究结果表明,当梳棉产量增加时,梳棉网中的后弯钩大量减少,这样就改善了纤维的伸直平行度,降低了精梳过程中的落棉。落棉量少的精梳棉条中的纤维长度分布与落棉量多的精梳棉条中的纤维长度分布几乎相差无几。为此,当时许多纺织厂增加了精梳纱的梳棉产量,但是梳棉产量的增加。势必使棉结杂质的排除量减少,从而使成纱棉杂增加。因此,一些纺织厂便增加了盖板速度以去除较多的盖板花,并把

关键词：精梳落棉经过棉卷落棉隔距双联梳棉机落棉率精梳条纤维长度分布精梳机梳理机