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Universal adaptive optics for microscopy through embedded neural network control

Light(Science & Applications) 2023年第12期12卷 2597-2609页

作者： Qi Hu martin Hailstone Jingyu Wang matthew Wincott Danail Stoychev Huriye Atilgan Dalia Gala Tai Chaiamarit Richard m.Parton Jacopo Antonello Adam m.Packer Ilan Davis martin J.Booth Department of Engineering Science University of OxfordOxfordUK Department of Biochemistry University of OxfordOxfordUK Department of Physiology Anatomyand GeneticsUniversity of OxfordOxfordUK

The resolution and contrast of microscope imaging is often affected by aberrations introduced by imperfect optical systems and inhomogeneous refractive structures in *** optics(AO)compensates these aberrations and restores diffraction limited performance.A wide range of AO solutions have been introduced,often tailored to a specific microscope type or *** now,a universal AO solution-one that can be readily transferred between microscope modalities-has not been *** propose versatile and fast aberration correction using a physics-based machine learning assisted wavefront-sensorless AO control(mLAO)*** previous mL methods,we used a specially constructed neural network(nn)architecture,designed using physical understanding of the general microscope image formation,that was embedded in the control loop of different microscope *** approach means that not only is the resulting nn orders of magnitude simpler than previous nn methods,but the concept is translatable across microscope *** demonstrated the method on a two-photon,a three-photon and a widefield three-dimensional(3D)structured illumination *** showed that the method outperformed commonly-used modal-based sensorless AO *** also showed that our mL-based method was robust in a range of challenging imaging conditions,such as 3D sample structures,specimen motion,low signal to noise ratio and activity-induced fluorescence ***,as the bespoke architecture encapsulated physical understanding of the imaging process,the internal nn configuration was no-longer a"black box",but provided physical insights on internal workings,which could influence future designs.

关键词： optics illumination correction

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多电荷离子双电子复合中的宇称不守恒效应(英文)

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复旦学报（自然科学版） 2007年第1期46卷 50-53页

作者： m G Kozlov G F Gribakin F J Currell Petersburg Nuclear Physics Institute Gatchina 188300 Russia School of mathematics and Physics Queen's University Belfast BT7 1NNNorthern Ireland United Kingdom

A parity nonconserving (PNC) asymmetry in the cross section for dielectronic recombination of polarized electrons on multiply charged ions with Z≥40 is discussed. This effect is strongly enhanced for close doubly-excited states of opposite parity in the intermediate compound ion. Such states are known for He-like ***, these levels have large energy and large radiative widths which hampers observation of the PNC asymmetry. We argue that accidentally degenerate states of more complex ions may be more suitable for the corresponding experiment.

关键词：奇偶不守恒不对称二维电子重组带电离子激发状态

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Patient comfort and quality in colonoscopy

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World Journal of Gastroenterology 2013年第15期19卷 2355-2361页

作者： Vivian E Ekkelenkamp Kevin Dowler Roland m Valori Paul Dunckley Department of Gastroenterology Gloucestershire Hospitals NHS TrustGloucester GL1 3NNUnited Kingdom Department of Gastroenterology and Hepatology Erasmus University Medical Center3000 CA RotterdamThe Netherlands

AIm: To explore the relationship of patient comfort and experience to commonly used performance indicators for colonoscopy. mETHODS: All colonoscopies performed in our four endoscopy centres are recorded in two reporting systems that log key performance indicators. From 2008 to 2011, all procedures performed by qualified endoscopists were evaluated; procedures performed by trainees were excluded. The following variables were measured: Caecal intubation rate (CIR), nurse-reported comfort levels (NRCL) on a scale from 1 to 5, polyp detection rate (PDR), patient experience of the procedure (worse than expected, as expected, better than expected), and use of sedation and analgesia. Pearson' s correlation coefficient was used to identify relationships between performance ***: A total of 17027 colonoscopies were performed by 23 independent endoscopists between 2008 and 2011. Caecal intubation rate varied from 79.0% to 97.8%, with 18 out of 23 endoscopists achieving a CIR of > 90%. The percentage of patients experiencing significant discomfort during their procedure (defined as NRCL of 4 or 5) ranged from 3.9% to 19.2% with an average of 7.7%. CIR was negatively correlated with NRCL-45 (r=-0.61, P midazolam (mean 1.9 mg, with a range of 1.1 to 3.5 mg) given by the endoscopist was negatively correlated with CIR (r=-0.59, P mbers of procedures performed by the endoscopists (r=0.64, P mfort and find more polyps. measuring patient comfort is valuable in monitoring performance.

关键词： Endoscopy Colonoscopy Quality Comfort Performance

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The m3Y Double Folding Dissipative model in Agreement with Precise Fusion Cross Sections

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Journal of modern Physics 2013年第5期4卷 1-4页

作者： I. I. Gontchar m. V. Chushnyakova Physics and Chemistry Department Omsk State Transport University Omsk Russia

Large numbers of precision fusion excitation functions were fitted in the literature using the nucleus-nucleus interaction potential having the Woods-Saxon shape. The diffuseness of this potential fusion ranges from 0.75 to 1.5 fm. This is much larger than the value of 0.65 fm required by the elastic scattering data. Trying to resolve this contradiction we develop the dissipative trajectory model based on the density-dependent m3Y nn-forces folded with the nuclear matter distribution. Resulting potential possesses the normal diffuseness about 0.65 fm. With this potential we reach the agreement with the data for 16O+208Pb, 28Si+208Pb, 32S+208Pb reactions within 5%.

关键词： Heavy Ion Fusion m3Y nn-Forces Double Folding Potential Fusion Excitation Function

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PNAS:科学家或成功实现利用基因疗法来治疗阿尔兹海默氏症

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现代生物医学进展 2017年第4期17卷 I0001-I0002页

作者： Loukia Katsouri[a] Yau m. Lim[a] Katrin Blondrath[a] Ioanna Eleftheriadou[b] Laura Lombardero[a] Amy m. Birch[a] Nazanin mirzaei[a] Elaine E. Irvine[c] Nicholas D. mazarakis[b], magdalena Sastre[a], [a]Division of Brain Sciences Imperial College London London W12 0NN United Kingdom [b]Gene Therapy Division of Brain Sciences Imperial College London London W12 0NN United Kingdom [c]Institute for Clinical Sciences Medical Research Council Clinical Sciences Centre London W12 0NN United Kingdom

日前,来自帝国理工学院的研究人员通过利用病毒将特殊的基因片段运输到小鼠大脑中，从而成功抑制小鼠患阿尔兹海默氏症，相关研究刊登于国际杂志PNAS上，该研究或为后期开发治疗诸如阿尔兹海默氏症等神经性疾病的新型疗法提供思路。

关键词：基因疗法治疗利用科学家神经性疾病基因片段研究人员后期开发

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New modified Controlled Bat Algorithm for Numerical Optimization Problem

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Computers, materials & Continua 2022年第2期70卷 2241-2259页

作者： Waqas Haider Bangyal Abdul Hameed Jamil Ahmad Kashif Nisar muhammad Reazul Haque Ag.Asri Ag.Ibrahim Joel J.P.C.Rodrigues m.Adil Khan Danda B.Rawat Richard Etengu Department of Computing and Technology Iqra University IslamabadPakistan Computer Science Kohat University of Science and Technology(KUST)KohatPakistan Faculty of Computing and Informatics University Malaysia SabahJalan UMSKota Kinabalu88400SabahMalaysia Faculty of Computing&Informatics Multimedia UniversityPersiaran MultimediaCyberjaya63100SelangorMalaysia Federal University of Piauí(UFPI) Teresina-PLBrazil Instituto de Telecomunicacoes Covilh?6201-001Portugal Department Computer Science and Technology Chang’an UniversityXi’anChina Department of Electrical Engineering and Computer Science Howard UniversityWashingtonDCUSA

Bat algorithm(BA)is an eminent meta-heuristic algorithm that has been widely used to solve diverse kinds of optimization *** leverages the echolocation feature of bats produced by imitating the bats’searching *** faces premature convergence due to its local search *** of using the standard uniform walk,the Torus walk is viewed as a promising alternative to improve the local search *** this work,we proposed an improved variation of BA by applying torus walk to improve diversity and *** *** Computerized Bat Algorithm(mCBA)approach has been examined for fifteen well-known benchmark test *** finding of our technique shows promising performance as compared to the standard PSO and standard *** proposed mCBA,BPA,Standard PSO,and Standard BA have been examined for well-known benchmark test problems and training of the artificial neural network(Ann).We have performed experiments using eight benchmark datasets applied from the worldwide famous machine-learning(mL)repository of *** results have shown that the training of an Ann with mCBA-nn algorithm tops the list considering exactness,with more superiority compared to the traditional *** mCBA-nn algorithm may be used effectively for data classification and statistical problems in the future.

关键词： Bat algorithm mCBA Ann mL Torus walk

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Preformation probability and kinematics of cluster emission yielding Pb-daughters

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Chinese Physics C 2023年第7期47卷 123-132页

作者： Joshua T.majekodunmi m.Bhuyan K.Anwar N.Abdullah Raj Kumar Institute of Engineering mathematics Universiti Malaysia PerlisArau02600PerlisMalaysia Center for Theoretical and Computational Physics Department of PhysicsFaculty of ScienceUniversity of MalayaKuala Lumpur 50603Malaysia School of Physics and materials Science Thapar Institute of Engineering and TechnologyPatialaPunjab 147004India

In the present study,the newly established preformation formula is applied for the first time to study the kinematics of the cluster emission from various radioactive nuclei,especially those that decay to the double shell closure^(208)Pb nucleus and its neighbors as *** recently proposed universal cluster preformation formula has been established based on the concepts that underscore the influence of mass and charge asymmetry(η_(A)andη_(Z)),cluster mass A_(c),and the Q-value,paving the way to quantify the energy contribution during preformation as well as during the tunneling process *** cluster-daughter interaction potential is obtained by folding the relativistic mean-field(RmF)densities with the recently developed microscopic R3Y using the NL 3^(*)and the phenomenological m3Y nn potentials to compare their *** penetration probabilities are calculated from the WKB *** the inclusion of the new preformation probability P_(0),the predicted half-lives of the R3Y and m3Y interactions are in good agreement with the experimental ***,a careful inspection reflects slight differences in the decay half-lives,which arise from their respective barrier *** P_(0)for systems with double magic shell closure^(208)Pb daughter are found to be an order of≈10^(2)higher than those with neighboring Pb daughter *** exploring the contributions of the decay energy,the recoil effect of the daughter nucleus is evaluated,in contrast to several other ***,the centrality of the Q-value in the decay process is demonstrated and redefined within the preformed cluster-decay ***,we have introduced a simple and intuitive set of criteria that governs the estimation of recoil energy in the cluster radioactivity.

关键词： relativistic mean field cluster radioactivity preformation probability decay width and half life recoil energy Q-value of the decay

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An automated multiwell plate reading flim microscope for live cell autofluorescence lifetime assays

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Journal of Innovative Optical Health Sciences 2014年第5期7卷 99-113页

作者： Douglas J.Kelly Sean C.Warren Sunil Kumar Joao L.Lagarto Benjamin T.Dyer Anca margineanu Eric W.-F.Lam Chris Dunsby Paul m.W.French Photonics Group Department of PhysicsImperial College London South Kensington CampusLondonSW72AZUK Institute of Chemical Biology Department of Chemistry Imperial College LondonSouth Kensington Campus LondonSWT 2AZUK National Heart&Lung Institute Imperial Centre for Eaperimental&Translational medicine Du Cane Road LondonW12 ONNUK Department of Surgery and Cancer Imperial Cllege London Du Cane RoadLondonW12 ONNUK Centre for Histopathology Imperial College London Du Cane RoadLondonW120NNUK

Fluorescence lifetime imaging(FLIm)is increasingly used to read out cellular autofluorescenceoriginating from the coenzyme NADH in the context of investigating cell metabolic *** here an automated multiwell plate reading FLIm microscope optimized for UV illumi-nation with the goal of extending high content fluorescence lifetime asays to readouts ofmetabolism,We demonstrate its application to automated cellular autofluorescence lifetime imaging and discuss the key practical issues associated with its *** particular,weillustrate its capability to read out the NADH-lifetime response of cells to metabolic modulators,thereby illustrating the potential of the instrument for cytotoxicity studies,assays for drugdiscovery and stratified medicine.

关键词： High content analysis FLIm NADH metabolism cisplatin.

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measurement of away-side broadening with self-subtraction of flow in Au+Au collisions at √snn=200 GeV

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Chinese Physics C 2020年第10期44卷 59-67页

作者： L.Adamczyk J.R.Adams J.K.Adkins G.Agakishiev m.m.Aggarwal Z.Ahammed I.Alekseev D.m.Anderson A.Aparin E.C.Aschenauer m.U.Ashraf F.G.Atetalla A.Attri G.S.Averichev V.Bairathi K.Barish A.Behera R.Bellwied A.Bhasin J.Bielcik J.Bielcikova L.C.Bland I.G.Bordyuzhin J.D.Brandenburg A.V.Brandin J.Butterworth H.Caines m.Calderón de la Barca Sánchez D.Cebra I.Chakaberia P.Chaloupka B.K.Chan F-H.Chang Z.Chang N.Chankova-Bunzarova A.Chatterjee D.Chen J.H.Chen X.Chen Z.Chen J.Cheng m.Cherney m.Chevalier S.Choudhury W.Christie X.Chu H.J.Crawford m.Csanád m.Daugherity T.G.Dedovich I.m.Deppner A.A.Derevschikov L.Didenko X.Dong J.L.Drachenberg J.C.Dunlop T.Edmonds N.Elsey J.Engelage G.Eppley S.Esumi O.Evdokimov A.Ewigleben O.Eyser R.Fatemi S.Fazio P.Federic J.Fedorisin C.J.Feng Y.Feng P.Filip E.Finch Y.Fisyak A.Francisco L.Fulek C.A.Gagliardi T.Galatyuk F.Geurts A.Gibson K.Gopal D.Grosnick W.Guryn A.I.Hamad A.Hamed S.Harabasz J.W.Harris S.He W.He X.H.He S.Heppelmann S.Heppelmann N.Herrmann E.Hoffman L.Holub Y.Hong S.Horvat Y.Hu H.Z.Huang S.L.Huang T.Huang X.Huang T.J.Humanic P.Huo G.Igo D.Isenhower W.W.Jacobs C.Jena A.Jentsch Y.JI J.Jia K.Jiang S.Jowzaee X.Ju E.G.Judd S.Kabana m.L.Kabir S.Kagamaster D.Kalinkin K.Kang D.Kapukchyan K.Kauder H.W.Ke D.Keane A.Kechechyan m.Kelsey Y.V.Khyzhniak D.P.Kikoła C.Kim B.Kimelman D.Kincses T.A.Kinghorn I.Kisel A.Kiselev m.Kocan L.Kochenda L.K.Kosarzewski L.Kramarik P.Kravtsov K.Krueger N.Kulathunga mudiyanselage L.Kumar S.Kumar R.Kunnawalkam Elayavalli J.H.Kwasizur R.Lacey S.Lan J.m.Landgraf J.Lauret A.Lebedev R.Lednicky J.H.Lee Y.H.Leung C.Li W.Li W.Li X.Li Y.Li Y.Liang R.Licenik T.Lin Y.Lin m.A.Lisa F.Liu H.Liu P.Liu P.Liu T.Liu X.Liu Y.Liu Z.Liu T.Ljubicic W.J.Llope R.S.Longacre N.S.Lukow S.Luo X.Luo G.L.ma L.ma R.ma Y.G.ma N.magdy R.majka D.mallick S.margetis C.markert H.S.matis J.A.mazer N.G.minaev S.mioduszewski B.mohanty I.mooney Z.moravcova D.A.morozov m.Nagy J.D.Nam Nasim md K.Nayak D.Neff J.m.Nelson D.B.Nemes m.Nie G.Nigmatkulov T.Niida L.V.Nogach T.Nonaka A.S.Nunes G.Odyniec A.Ogawa Abilene Christian University AbileneTexas 79699 AGH University of Science and Technology FPACSCracow 30-059Poland Alikhanov Institute for Theoretical and Experimental Physics NRC"Kurchatov Institute" Moscow 117218Russia Argonne National Laboratory ArgonneIllinois 60439 American University of Cairo New Cairo 11835New CairoEgypt Brookhaven National Laboratory UptonNew York 11973 University of California BerkeleyCalifornia 94720 University of California DavisCalifornia 95616 University of California Los AngelesCalifornia 90095 University of California RiversideCalifornia 92521 Central China Normal University WuhanHubei 430079 University of Illinois at Chicago ChicagoIllinois 60607 Creighton University OmahaNebraska 68178 Czech Technical University in Prague FNSPEPrague 11519Czech Republic Technische Universität Darmstadt Darmstadt 64289Germany ELTE Eötvös Loránd University BudapestHungary H-1117 Frankfurt Institute for Advanced Studies FIAS Frankfurt 60438Germany Fudan University Shanghai 200433 University of Heidelberg Heidelberg 69120Germany University of Houston HoustonTexas 77204 Huzhou University HuzhouZhejiang 313000 Indian Institute of Science Education and Research(IISER) Berhampur 760010India Indian Institute of Science Education and Research(IISER)Tirupati Tirupati 517507India Indian Institute Technology PatnaBihar 801106India Indiana University BloomingtonIndiana 47408 Institute of modern Physics Chinese Academy of SciencesLanzhouGansu 730000 University of Jammu Jammu 180001India Joint Institute for Nuclear Research Dubna 141980Russia Kent State University KentOhio 44242 University of Kentucky LexingtonKentucky 40506-0055 Lawrence Berkeley National Laboratory BerkeleyCalifornia 94720 Lehigh University BethlehemPennsylvania 18015 max-Planck-Institut für Physik Munich 80805Germany michigan State University East LansingMichigan 48824 National Research Nuclear University mEPhI Moscow 115409Russia National Institute of Science Education and Research HBNIJatni 752050Indi

High transverse momentum(pT)particle production is suppressed owing to the parton(jet)energy loss in the hot dense medium created in relativistic heavy-ion *** of energy at low-to-modest pT has been difficult to measure,owing to large anisotropic *** report a data-driven method for background evaluation and subtraction,exploiting the away-side pseudorapidity gaps,to measure the jetlike correlation shape in Au+Au collisions at √snn=200 GeV in the STAR *** correlation shapes,for trigger particles pT>3GeV/c and various associated particle pT ranges within 0.5medium created in central heavy-ion collisions.

关键词： di-hadron correlations jet heavy-ion

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methods for a blind analysis of isobar data collected by the STAR collaboration

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Nuclear Science and Techniques 2021年第5期32卷 43-50页

作者： J.Adam L.Adamczyk J.R.Adams J.K.Adkins G.Agakishiev m.m.Aggarwal Z.Ahammed I.Alekseev D.m.Anderson A.Aparin E.C.Aschenauer m.U.Ashraf F.G.Atetalla A.Attri G.S.Averichev V.Bairathi K.Barish A.Behera R.Bellwied A.Bhasin J.Bielcik J.Bielcikova L.C.Bland I.G.Bordyuzhin J.D.Brandenburg A.V.Brandin J.Butterworth H.Caines m.Calderon de la Barca Sanchez D.Cebra I.Chakaberia P.Chaloupka B.K.Chan F-H.Chang Z.Chang N.Chankova-Bunzarova A.Chatterjee D.Chen J.Chen J.H.Chen X.Chen Z.Chen J.Cheng m.Cherney m.Chevalier S.Choudhury W.Christie X.Chu H.J.Crawford m.Csanad m.Daugherity T.G.Dedovich I.m.Deppner A.A.Derevschikov L.Didenko X.Dong J.L.Drachenberg J.C.Dunlop T.Edmonds N.Elsey J.Engelage G.Eppley S.Esumi O.Evdokimov A.Ewigleben O.Eyser R.Fatemi S.Fazio P.Federic J.Fedorisin C.J.Feng Y.Feng P.Filip E.Finch Y.Fisyak A.Francisco L.Fulek C.A.Gagliardi T.Galatyuk F.Geurts A.Gibson K.Gopal X.Gou D.Grosnick W.Guryn A.I.Hamad A.Hamed S.Harabasz J.W.Harris S.He W.He X.H.He Y.He S.Heppelmann S.Heppelmann N.Herrmann E.Hoffman L.Holub Y.Hong S.Horvat Y.Hu H.Z.Huang S.L.Huang T.Huang X.Huang T.J.Humanic P.Huo G.Igo D.Isenhower W.W.Jacobs C.Jena A.Jentsch Y.Ji J.Jia K.Jiang S.Jowzaee X.Ju E.G.Judd S.Kabana m.L.Kabir S.Kagamaster D.Kalinkin K.Kang D.Kapukchyan K.Kauder H.W.Ke D.Keane A.Kechechyan m.Kelsey Y.V.Khyzhniak D.P.Kikoła C.Kim B.Kimelman D.Kincses T.A.Kinghorn I.Kisel A.Kiselev m.Kocan L.Kochenda L.K.Kosarzewski L.Kramarik P.Kravtsov K.Krueger N.Kulathunga mudiyanselage L.Kumar S.Kumar R.Kunnawalkam Elayavalli J.H.Kwasizur R.Lacey S.Lan J.m.Landgraf J.Lauret A.Lebedev R.Lednicky J.H.Lee Y.H.Leung C.Li C.Li W.Li W.Li X.Li Y.Li Y.Liang R.Licenik T.Lin Y.Lin m.A.Lisa F.Liu H.Liu P.Liu P.Liu T.Liu X.Liu Y.Liu Z.Liu T.Ljubicic W.J.Llope R.S.Longacre N.S.Lukow S.Luo X.Luo G.L.ma L.ma R.ma Y.G.ma N.magdy R.majka D.mallick S.margetis C.markert H.S.matis J.A.mazer N.G.minaev S.mioduszewski B.mohanty I.mooney Z.moravcova D.A.morozov m.Nagy J.D.Nam md.Nasim K.Nayak D.Neff J.m.Nelson D.B.Nemes m.Nie G.Nigmatkulov T.Niida L.V.Nogach T.Nonak Christian University AbileneTX 796992 AGH University of Science and Technology FPACSCracow 30-059Poland Alikhanov Institute for Theoretical and Experimental Physics NRC"Kurchatov Institute" MoscowRussia 117218 Argonne National Laboratory ArgonneIL 60439 American University of Cairo New CairoNew Cairo 11835Egypt Brookhaven National Laboratory UptonNY 11973 University of California BerkeleyCA 94720 University of California DavisCA 95616 University of California Los AngelesCA 90095 University of California RiversideCA 92521 Central China Normal University Wuhan 430079 University of Illinois at Chicago ChicagoIL 60607 Creighton University OmahaNE 68178 Czech Technical University in Prague FNSPEPrague 11519Czech Republic Technische Universitat Darmstadt Darmstadt 64289Germany ELTE Eotvos Lorand University Budapest 1117Hungary Frankfurt Institute for Advanced Studies FIAS Frankfurt 60438Germany Fudan University Shanghai 200433 University of Heidelberg 69120 HeidelbergGermany University of Houston HoustonTX 77204 Huzhou University Huzhou 313000 Indian Institute of Science Education and Research(IISER) Berhampur 760010India Indian Institute of Science Education and Research(IISER)Tirupati Tirupati 517507India Indian Institute Technology PatnaBihar 801106India Indiana University BloomingtonIN 47408 Institute of modern Physics Chinese Academy of SciencesLanzhou 730000 University of Jammu Jammu 180001India Joint Institute for Nuclear Research DubnaRussia 141980 Kent State University KentOH 44242 University of Kentucky LexingtonKY 40506-0055 Lawrence Berkeley National Laboratory BerkeleyCA 94720 Lehigh University BethlehemPA 18015 max-Planck-Institut fur Physik 80805 MunichGermany michigan State University East LansingMI 48824 National Research Nuclear University mEPhI MoscowRussia 115409 National Institute of Science Education and Research HBNIJatni 752050India National Cheng Kung University Tainan 70101 Nuclear Physics Institute of the CAS Rez 25068Czech Republic Ohio State University

In 2018,the STAR collaboration collected data from^(96)_(44)Ru+^(96)_(44)Ru and^(96)_(40)Zr+^(96)_(40)Zr at√^(S)nn=200 Ge V to search for the presence of the chiral magnetic effect in collisions of *** isobar collision species alternated frequently between 9644 Ru+^(96)_(44)Ru and^(96)_(40)Zr+^(96)_(40)*** order to conduct blind analyses of studies related to the chiral magnetic effect in these isobar data,STAR developed a three-step blind analysis *** are initially provided a"reference sample"of data,comprised of a mix of events from the two species,the order of which respects time-dependent changes in run *** tuning analysis codes and performing time-dependent quality assurance on the reference sample,analysts are provided a species-blind sample suitable for calculating efficiencies and corrections for individual≈30-min data-taking *** this sample,species-specific information is disguised,but individual output files contain data from a single isobar *** run-by-run corrections and code alteration subsequent to these corrections are allowed at this *** these modifications,the"frozen"code is passed over the fully un-blind data,completing the blind *** a check of the feasibility of the blind analysis procedure,analysts completed a"mock data challenge,"analyzing data from Au+Au collisions at√^(S)nn=27 Ge V,collected in *** Au+Au data were prepared in the same manner intended for the isobar blind *** details of the blind analysis procedure and results from the mock data challenge are presented.

关键词： Blind analysis Chiral magnetic effect Heavy-ion collisions

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