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Associations between health-related fitness and patient-reported symptoms in newly diagnosed breast cancer patients

journal of Sport and Health Science 2024年第6期13卷 851-862页

作者： Ki-Yong An Fernanda Z.Arthuso Myriam Filion spencer j.allen Stephanie M.Ntoukas Gordon j.Bell jessica McNeil Qinggang Wang Margaret L.McNeely jeff K.Vallance Lin Yang S.Nicole Culos-Reed Leanne Dickau john R.Mackey Christine M.Friedenreich Kerry S.Courneya Faculty of Kinesiology Sportand RecreationCollege of Health SciencesUniversity of AlbertaEdmonton T6G 2H9Canada Department of Kinesiology School of Health and Human SciencesUniversity of North Carolina at GreensboroGreensboroNC 27412USA Department of Cancer Epidemiology and Prevention Research Cancer Care AlbertaAlberta Health ServicesCalgary T2S 3C3Canada Faculty of Rehabilitation Medicine University of AlbertaEdmonton T6G 2H9Canada Faculty of Health Disciplines Athabasca UniversityAthabasca T9S 3A3Canada Department of Oncology Cumming School of MedicineUniversity of CalgaryCalgary T2N 4N1Canada Faculty of Kinesiology University of CalgaryCalgary T2N 1N4Canada Faculty of Medicine and Dentistry University of AlbertaEdmonton T6G 2H9Canada

Background:Newly diagnosed breast cancer patients experience symptoms that may affect their quality of life,treatment outcomes,and *** and managing breast cancer-related symptoms soon after diagnosis is *** purpose of this study was to investigate the associations between health-related fitness(HRF)and patient-reported symptoms in newly diagnosed breast cancer ***:This study utilized baseline data from the Alberta Moving Beyond Breast Cancer Cohort Study that were collected within 90 days of *** measures included peak cardiopulmonary fitness(peak volume of oxygen consumption(VO_(2peak))),maximal muscular strength and endurance,flexibility,and body *** measures included depression,sleep quality,and *** multivariable logistic regression was performed for ***:Of 1458 participants,51.5%reported poor sleep quality,26.5%reported significant fatigue,and 10.4%reported moderate *** multivariable-adjusted models,lower relative VO_(2peak)was independently associated with a greater likelihood of all symptom measures,including moderate depression(p<0.001),poor sleep quality(p=0.009),significant fatigue(p=0.008),any symptom(p<0.001),and multiple symptoms(p<0.001).VO_(2peak)demonstrated threshold associations with all symptom measures such that all 3 lower quartiles exhibited similar elevated risk compared to the highest *** strength of the threshold associations varied by the symptom measure with odds ratios ranging from-1.5 for poor sleep quality to-3.0 for moderate depression and multiple ***,lower relative upper body muscular endurance was also independently associated with fatigue in a dose-response manner(p=0.001),and higher body weight was independently associated with poor sleep quality in an inverted U pattern(p=0.021).Conclusion:Relative VO_(2peak)appears to be a critical HRF component associated with multiple patient-reported symptoms in newly diag

关键词： Breast cancer Fatigue Depression Sleep quality Cardiorespiratory fitness

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Himalayan Tectonics:Preface

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Geoscience Frontiers 2019年第3期10卷 791-792页

作者： Kyle Larson Christopher j. spencer Tectonics and Geodynamics Earth Environmental and Geographical Sciences IKBSAS University of British Columbia Earth Dynamics Research Group The Institute for Geoscience Research (TIGeR) Department of Applied Geology Curtin University

The Himalayan-Tibetan orogen system serves as the modern paradigm for understanding convergence-related processes in orogenic belts. The advancements made studying the region have been applied to other ancient orogenic belts leading not only to a better understanding of their development, but also of secular changes in collisional processes. As more advanced methodologies are introduced and utilized in geological research, the type, scale, and quality of data available enable quantification of geological processes not previously possible. These complex and robust datasets now form the core of many of the research projects undertaken across the Himalaya and continue to provide unprecedented insight into the myriad different aspects of the evolution of the collisional system.

关键词： Himalayan-Tibetan system evolution

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Visualising data distributions with kernel density estimation and reduced chi-squared statistic

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Geoscience Frontiers 2017年第6期8卷 1247-1252页

作者： C.j.spencer C.Yakymchuk M.Ghaznavi Earth Dynamics Research Group The Institute of Geoscience ResearchDepartment of Applied GeologyCurtin UniversityPerthAustralia Department of Earth and Environmental Sciences University of WaterlooWaterlooCanada David R.Cheriton School of Computer Science University of WaterlooWaterlooCanada

The application of frequency distribution statistics to data provides objective means to assess the nature of the data distribution and viability of numerical models that are used to visualize and interpret *** commonly used tools are the kernel density estimation and reduced chi-squared statistic used in combination with a weighted *** to the wide applicability of these tools,we present a java-based computer application called KDX to facilitate the visualization of data and the utilization of these numerical tools.

关键词： Data visualisation Kernel density estimation Reduced chi-squared statistic Mean square weighted deviation Geostatistics

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Strategies towards statistically robust interpretations of in situ U-Pb zircon geochronology

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Geoscience Frontiers 2016年第4期7卷 581-589页

作者： Christopher j.spencer Christopher L.Kirkland Richard j.M.Taylor The Institute of Geoscience Research(TIGeR) Department of Applied GeologyWestern Australian School of MinesCurtin UniversityWA 6102Australia Centre for Exploration Targeting-Curtin Node Department of Applied GeologyWestern Australian School of MinesCurtin UniversityWA 6102Australia Australian Research Council Centre of Excellence for Core to Crust Fluid SystemsPerthWA 6102Australia

Zircon U-Pb geochronology has become a keystone tool across Earth science, arguably providing the gold standard in resolving deep geological time. The development of rapid in situ analysis of zircon （via laser ablation and secondary ionization mass spectrometry） has allowed for large amounts of data to be generated in a relatively short amount of time and such large volume datasets offer the ability to address a range of geological questions that would otherwise remain intractable （e.g. detrital zircons as a sedi- ment fingerprinting method）. The ease of acquisition, while bringing benefit to the Earth science com- munity, has also led to diverse interpretations of geochronological data. In this work we seek to refocus U -Pb zircon geochronology toward best practice by providing a robust statistically coherent workflow. We discuss a range of data filtering approaches and their inherent limitations （e.g. discordance and the reduced chi-squared; MSWD）. We evaluate appropriate mechanisms to calculate the most geologically appropriate age from both 238U/206pb and 207pb/206pb ratios and demonstrate the cross over position when chronometric power swaps between these ratios. As our in situ analytical techniques become progressively more precise, appropriate statistical handing of U-Pb datasets will become increasingly pertinent.

关键词： Zircon Geochronology U-Pb Geostatistics MSWD

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Timescales of geological processes: Preface

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Geoscience Frontiers 2019年第1期10卷 1-3页

作者： Andrew Putnis Christopher j.spencer Tom Raimondo The Institute for Geoscience Research School of Earth and Planetary Science Curtin University School of Natural and Built Environments University of South Australia

*** One of the major challenges in Geoscience is to understand how the formation and evolution of the Earth System are governed by timescales-that is,how the various geological processes that continue to contribute to its present-day structure and composition operated in the deep *** traditional view of such processes refers to events that occur at immense spatial scales and over hundreds of millions of years,constrained in most cases by the ages of rocks determined using isotopic dating methods or the fossil ***,the modern view of geological processes has increasingly acknowledged that their durations can be significantly shorter than previously thought possible,or indeed detectable without recent analytical *** are a prime example of rapid,high energy and episodic events that have a profound effect on subsequent processes such as metamorphism,fluid transport,and ore formation e the evidence of which is written in microstructures,compositional zoning,and P-T *** studies have also revealed that the reaction rates between fluids and rocks can be extremely rapid relative to geological *** has led to the notion that geological processes are not necessarily continuous over millions of years but may,in fact,be sporadic,with long periods where essentially no reactions take place punctuated by periods of intense activity.

关键词： In Preface Timescales of geological processes

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Secular change in earth processes： Preface

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Geoscience Frontiers 2018年第4期9卷 965-966页

作者： Richard M.Palin Christopher j.spencer Department of Geology and Geological Engineering Colorado School of Mines Golden CO 80401 USA The Institute of Geoscience Research (TIGER) School of Earth and Planetary Sciences Curtin University WA 6102 Australia

*** Uniformitarianism is a traditional approach used in many areas of geoscience that assumes the geologic processes observed today operated similarly throughout all of Earth history（Hutton,1788;Windley,1993）,with such an ideology commonly encapsulated by the maxim＂the present is the key to the past＂.This concept is closely associated with the philosophical principle of Occam’s razor.

关键词： Secular change in earth processes Preface

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Exploring public perception and willingness to pay for a renewable source of energy:evidence from an emerging economy of renewable-energy development

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Clean Energy 2024年第2期8卷 177-188页

作者： Mohammed j.K.Bashir Senadjki Abdelhak Wael A.Salah Mai Abuhelwa School of Engineering&Technology Central Queensland University120 Spencer St.MelbourneQLD 3000Australia Faculty of Business and Finance Universiti Tunku Abdul RahmanKamparPerakMalaysia Department of Electrical Engineering College of Engineering and TechnologyPalestine Technical University-KadooriePO Box 7Yafa StreetTulkarmPalestine Department of Electrical Engineering and Computer Science University of MissouriColumbiaMO 65211USA

The study focuses on the transition from conventional energy sources to sustainable renewable energy(RE)in Palestine,particularly in the West Bank and Gaza *** research aims to understand the relationship between key factors and residents’willingness to invest in the RE sector,with a specific focus on the impact of *** the unified theory of acceptance and use of technology,the study analyzes data from 400 residents through a questionnaire and employs ordinary least-squares regression analysis with Eviews *** key findings indicate that residents’inclination to invest in RE is significantly influenced by factors such as resource availability,knowledge level and power ***,the study suggests that educated residents are more likely to invest in RE when factors such as knowledge,effort expectation,enabling conditions and resource availability are relatively *** conclusion emphasizes the importance of policymakers’allocating sufficient funds to research and development to promote technological innovation in RE sources,thereby enhancing the population’s energy efficiency.

关键词： renewable energy technology energy security public perceptions sustainable development

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Transforming bilayer MoS2 into single-layer with strong photoluminescence using UV-ozone oxidation

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Nano Research 2015年第12期8卷 3878-3886页

作者： Weitao Su Naresh Komar Steve j. spencer Ning Dai Debdulal Roy Institute of Materials Physics Hangzhou Dianzi University Hangzhou 310018 China Ningbo Institute of Materials Technology & Engineering Chinese Academy of Sciences Ningbo 315201 China National Physical Laboratory Hampton Road Teddington Middlesex TWI 10LW UK

The use of single-layer MoS2 in light emitting devices requires innovative methods to enhance its low photoluminescence （PL） quantum yield. In this work, we report that single-layer MoS2 with a strong PL can be prepared by oxidizing bilayer MoS2 using W-ozone oxidation. We show that as compared to mechanically-exfoliated single-layer MoS2, the PL intensity of the single-layer MoS2 prepared by W-ozone oxidation is enhanced by 20-30 times. We demonstrate that the PL intensity of both neutral excitons and trions （charged excitons） can be greatly enhanced in the oxidized MoS2 samples. These results provide novel insights into the PL enhancement of single-layer MoS2.

关键词： single-layer MoS2 W-ozone oxidation photoluminescence enhancement tip-enhanced Raman spectroscopy

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Development of a Balanced Adaptive Time‑Stepping Strategy Based on an Implicit jFNK‑DG Compressible Flow Solver

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Communications on Applied Mathematics and Computation 2022年第2期4卷 728-757页

作者： Yu Pan Zhen‑Guo Yan joaquim Peiró spencer j.Sherwin Department of Aeronautics Imperial College LondonLondonUK State Key Laboratory of Aerodynamics China Aerodynamics Research and Development CenterMianyang 621000SichuanChina

A balanced adaptive time-stepping strategy is implemented in an implicit discontinuous Galerkin solver to guarantee the temporal accuracy of unsteady simulations.A proper relation between the spatial,temporal and iterative errors generated within one time step is *** an estimate of temporal and spatial error using an embedded RungeKutta scheme and a higher order spatial discretization,an adaptive time-stepping strategy is proposed based on the idea that the time step should be the maximum without obviously infuencing the total error of the *** designed adaptive time-stepping strategy is then tested in various types of problems including isentropic vortex convection,steady-state fow past a fat plate,Taylor-Green vortex and turbulent fow over a circular cylinder at Re=*** results indicate that the adaptive time-stepping strategy can maintain that the discretization error is dominated by the spatial error and relatively high efciency is obtained for unsteady and steady,well-resolved and under-resolved simulations.

关键词： Adaptive time-stepping Unsteady simulations High order Discontinuous Galerkin Implicit time integration

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Granular titanite from the Roter Kamm crater in Namibia:Product of regional metamorphism,not meteorite impact

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Geoscience Frontiers 2022年第3期13卷 156-163页

作者： Aaron j.Cavosie Christopher j.spencer Noreen Evans Kai Rankenburg Robert j.Thomas Paul H.Macey Space Science and Technology Centre and The Institute for Geoscience Research School of Earth and Planetary ScienceCurtin UniversityPerthWA 6102Australia Dept.of Geological Sciences and Geological Engineering Queen’s UniversityOntarioCanada john de Laeter Centre Curtin UniversityPerthWA 6102Australia Council for Geoscience BellvilleWestern CapeSouth Africa

Accessory minerals with so-called granular texture have risen in importance as geochronological tools for U-Pb dating of meteorite impact events. Grain-scale recrystallization, typically triggered by a combination of high-strain deformation and post-impact heating, can create a polycrystalline microstructure consisting of neoblasts that expel radiogenic Pb, which are thus ideal for isotopic dating. While granular domains in zircon and monazite from shocked rocks have been demonstrated to preserve impact ages,few U-Pb dating studies have been conducted on granular microstructures in titanite(CaTiSiO;). Here we report the occurrence of granular-textured titanite from ~2020 Ma granite basement rock exposed in the rim of the 4–5 Ma Roter Kamm impact structure in Namibia. Orientation mapping reveals two microstructurally distinct titanite populations: one consisting of strained/deformed grains, and the other consisting of grains that comprise aggregates of strain-free neoblasts. In situ U-Pb geochronology on 37 grains shows that most grains from both titanite populations yield indistinguishable U-Pb dates of ca.1025 Ma, consistent with the observed microstructures forming during the Mesoproterozoic Namaqua Orogeny. Only four grains preserved older age domains, recording ca. 1875 Ma Paleoproterozoic metamorphism. Two significant observations emerge:(1) none of the analyzed titanite grains yield the 2020 Ma igneous crystallization age previously established from zircon in the same sample, and(2) no age-resetting was detected that could be attributed to the 4 to 5 Ma Roter Kamm impact *** the similarity of the neoblastic microstructure to minerals from other sites with an established impact provenance, the granular texture and near-complete Pb-loss in titanite from Roter Kamm granite instead records a Paleo-to Mesoproterozoic polymetamorphic history, rather than Miocene age shockrelated processes. These results highlight the critical importance of grain-scale cont

关键词： Namibia Roter Kamm Titanite EBSD Geochronology

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