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内洛尔公牛的饲料转化率及其与胴体品质、非胴体品质和肉品质的关系

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饲料博览 2016年第5期26卷 55-55页

作者： Nascimento M l souza a r d l Chaves A S MCesar A S Tullio r r Medeiros S r Mour?o G B rosa A N FeijóG l d Alencar M M lanna d P d

试验选取内诺尔公牛575只,研究剩余采食量(rFI)、1*rFI与体增重的总和(rIG)与胴体品质、非胴体品质和肉品质之间的关系。rFI是由预测采食量与实际采食量的差值。根据rFI和rIG的平均值偏差±0.5来划分高效和低效的动物。建立一个混合模型... 详细信息

试验选取内诺尔公牛575只,研究剩余采食量(rFI)、1*rFI与体增重的总和(rIG)与胴体品质、非胴体品质和肉品质之间的关系。rFI是由预测采食量与实际采食量的差值。根据rFI和rIG的平均值偏差±0.5来划分高效和低效的动物。建立一个混合模型,rFI或rIG和同期群作为固定影响因素,初始年龄作为协变量,雄性牲畜和试验周期作为随机变量,建立每个评估特征的回归斜率方程。rIG与眼肌面积呈正相关关系。高效rFI组动物的肝脏和内部脂肪比例均低于低效rFI组。与低效rFI组和低效rIG组相比,高效rFI组rIG高效组动物的肌内脂肪提取率分别减少了11.8%和11.2%。与rFI低效组相比,rFI高效组的动物的瘦肉率更高。

关键词：肉用牛印度牛饲料效率体内脂肪嫩度内脏器官

Spouting behavior of binary particle mixtures of different densities: Fluid dynamics and particle segregation

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Particuology 2019年第1期17卷 58-66页

作者： K.G. Santos r.C. Santana d.l. souza V.V. Murata M.A.S. Barrozo Federal University ofTriangulo Mineiro Chemical Engineering DepartmentUniverdecidade CampusUberabaMGBrazil Federal University of Uberlandia Chemical Engineering SchoolUberlandiaMG. Brazil

Numerous industrial applications of spouted beds involve a mixture of granular particles, where differences in particle size, density, and shape can cause particle segregation, affecting the quality of flow and decreasing product homogeneity. The aim of this study was to investigate the particle segregation and fluid dynamics of a conical spouted bed operating with a binary mixture of particles of different densities. Using glass beads and polyethylene particles with a diameter of 4 mm, we determined the effects of the mass fraction of denser particles and static bed height on the minimum spouting condition and mixture index. The pressure drop and airflow in the minimum spouting condition increased with an increase in bed height or jetsam concentration. regarding particle segregation, the jetsam particles tended to concentrate near the bottom, at the spout–annulus interface because they have a shorter trajectory than the lighter particles in the fountain region. Jetsam-rich mixtures with high initial static bed heights exhibited more efficient particle mixing, excluding those at the bottom of the bed.

关键词： density Segregation Spouted bed Binary mixtures

Kinetic rates of the Fischer Tropsch Synthesis on a Co/Nb_2O_5 Catalyst

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Journal of Natural Gas Chemistry 2006年第4期15卷 307-312页

作者： Víctor r.Ahón Paulo l.C.lage Carlos d.d.de souza Fabiana M.Mendes Martin Schmal Federal University of rio de Janeiro Programa de Engenharia Química COPPE/UFRJ C.P.6850221941-972Rio de JaneiroRJBrazil

The kinetics of the Fischer-Tropsch reaction over a Co/Nb2O5 catalyst in a fixed bed reactor was investigated experimentally. Experiments were carried out under isothermal and isobaric conditions （T=543 K, P=2.1 MPa） and under different conditions of several H2/CO feed molar ratio （0.49-4.79）, space velocities （0.2-3.8 h^-1）, mass of catalyst （0.3-1.5 g）, and CO conversion （10%-29%）. Synthesis gas conversion was measured and data were reduced to estimate the kinetic parameters for different langmuir-Hinshelwood rate expressions. differential and integral reactor models were used for the nonlinear regression of kinetics parameters. One of the rate equations could well explain the data. The hydrocarbon product distributions that were experimentally determined exhibited an unusual behavior, and a possible explanation was discussed.

关键词： Fischer-Tropsch natural gas kinetics selectivity

Biodiversity of Arbuscular Mycorrhizal (AM) fungi in mangroves of Goa in West India

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Journal of Forestry research 2013年第3期24卷 515-523页

作者： James d'souza Bernard Felinov rodrigues department of Botany Goa UniversityGoa 403 206 India

Seventeen mangrove species of eight families at seven river- ine and fringe habitats in Goa West India were surveyed for Arbuscular Mycorrhizal （AM） fungal diversity. Sixteen species were found to be mycorrhizal and one species showed no AM fungal colonization. AM root colonization was recorded at all seven sites and ranged from 6%-77%. Maximum root colonization was recorded in Excoecaria agal- locha （77%） and minimum colonization in Avicennia marina （6%）. Paris-type colonization was predominant at all sites. Auxiliary cells were recorded in roots of Acanthus ilicifolius, Ceriops tagal and Sonneretia alba. AM fungal root colonization and spore density varied by plant species and site. Site average spore density ranged from 1.84 spores.g^-1 to 0.54 spores.g-1 of soil. In total, 28 AM fungal species of five genera, viz. Glomus, Acaulospora, Scutellospora, Gigaspora and Entrophospora, were recovered. Glomus was the dominant genus, three species of which were sporocarpic forms. Maximum site species richness （Sr） ranged from 16 to 5. Species richness was maximum in A. ilicifolius where seven species of three genera were recovered. Based on relative abun- dance （rA） and isolation frequency （IF）, two common species, viz. G. intraradices and A. laevis, were recovered from all seven sites.

关键词： Glomus intraradices root colonization Paris type sporedensity rhizosphcre

Practical issues concerning tear protein assays in dry eye

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Eye and Vision 2014年第1期1卷 34-45页

作者： Sharon d’souza louis Tong Narayana Nethralaya Superspeciality Eye Hospital and Post Graduate Institute BangaloreKarnatakaIndia. Singapore Eye research Institute 11Third Hospital AvenueSingapore 168751Singapore. Singapore National Eye Center SingaporeSingapore. duke-NUS Graduate Medical School SingaporeSingapore. Yong loo lin School of Medicine National University of SingaporeSingaporeSingapore.

dry eye is a common clinical condition diagnosed by cumulative evidence of symptoms and *** new treatments in dry eye are either expensive,invasive,have potential for side effects,or are not easily *** severe dry eye,the ideal modality of treatment to begin with is often not clear as specific molecular disturbances are not evident from just examination of clinical *** the effects of ongoing treatment is not straight forward since there is lack of agreement between clinical signs and *** is a need to have more objective methods of selecting treatment for dry eye and monitoring the effect of ***,there are many new technologies applied to the discovery of tear biomarkers,for e.g.,mass spectrometry based proteomics techniques and multiplex assays such as the bead-based sandwich indirect immunofluorescent *** proteins assays have even been made available as point-of-care *** review focuses on the evidence for the involvements of tear proteins in dry eye,possible changes in tear concentrations with therapy and the strength of evidence regarding dry eye *** remains to be done in terms of developing office-based assays and ascertaining their reliability,but current evidence suggests that tear proteins have a role in the clinical practice of dry eye.

关键词： Human dry eye review Tear Proteomics Biomarker

Polyethylene glycol has immunoprotective effects on sciatic allografts, but behavioral recovery and graft tolerance require neurorrhaphy and axonal fusion

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Neural regeneration research 2025年第4期20卷 1192-1206页

作者： Tyler A.Smith liwen Zhou Cameron l.Ghergherehchi Michelle Mikesh Cathy Z.Yang Haley O.Tucker JuliAnne Allgood Jared S.Bushman George d.Bittner department of Molecular Biosciences University of Texas at AustinAustinTXUSA department of Neuroscience University of Texas at AustinAustinTXUSA division of Pharmaceutical Sciences University of WyomingLaramieWYUSA

Behavioral recovery using(viable)peripheral nerve allografts to repair ablation-type(segmental-loss)peripheral nerve injuries is delayed or poor due to slow and inaccurate axonal ***,such peripheral nerve allografts undergo immunological rejection by the host immune *** contrast,peripheral nerve injuries repaired by polyethylene glycol fusion of peripheral nerve allografts exhibit excellent behavioral recovery within weeks,reduced immune responses,and many axons do not undergo Wallerian *** relative contribution of neurorrhaphy and polyethylene glycol-fusion of axons versus the effects of polyethylene glycol per se was unknown prior to this *** hypothesized that polyethylene glycol might have some immune-protective effects,but polyethylene glycol-fusion was necessary to prevent Wallerian degeneration and functional/behavioral *** examined how polyethylene glycol solutions per se affect functional and behavioral recovery and peripheral nerve allograft morphological and immunological responses in the absence of polyethylene glycol-induced axonal ***-type sciatic nerve injuries in outbred Sprague–dawley rats were repaired according to a modified protocol using the same solutions as polyethylene glycol-fused peripheral nerve allografts,but peripheral nerve allografts were loose-sutured(loose-sutured polyethylene glycol)with an intentional gap of 1–2 mm to prevent fusion by polyethylene glycol of peripheral nerve allograft axons with host *** to negative control peripheral nerve allografts not treated by polyethylene glycol and in contrast to polyethylene glycol-fused peripheral nerve allografts,animals with loose-sutured polyethylene glycol peripheral nerve allografts exhibited Wallerian degeneration for all axons and myelin degeneration by 7 days postoperatively and did not recover sciatic-mediated behavioral functions by 42 days *** morphological signs of rejection,such as col

关键词： allograft rejection axotomy macrophage myelin nerve repair polyethylene glycol(PEG) sciatic nerve T cell transplantation Wallerian degeneration

Molecular mechanisms of viral hepatitis induced hepatocellular carcinoma

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World Journal of Gastroenterology 2020年第38期26卷 5759-5783页

作者： Simmone d'souza Keith CK lau Carla S Coffin Trushar r Patel department of Microbiology Immunologyand Infectious DiseasesCumming School of MedicineUniversity of CalgaryCalgary T2N 1N4ABCanada department of Chemistry and Biochemistry Alberta RNA Research and Training InstituteUniversity of LethbridgeLethbridge T1K3M4ABCanada

Chronic infection with viral hepatitis affects half a billion individuals worldwide and can lead to cirrhosis,cancer,and liver *** cancer is the third leading cause of cancer-associated mortality,of which hepatocellular carcinoma(HCC)represents 90%of all primary liver *** tumors like HCC are complex and have heterogeneous tumor genomic profiles contributing to complexity in diagnosis and *** infection with hepatitis B virus(HBV),hepatitis delta virus(HdV),and hepatitis C virus(HCV)are the greatest etiological risk factors for *** to the significant role of chronic viral infection in HCC development,it is important to investigate direct(viral associated)and indirect(immune-associated)mechanisms involved in the pathogenesis of *** mechanisms used by HBV,HCV,and HdV that drive hepatocarcinogenesis include persistent liver inflammation with an impaired antiviral immune response,immune and viral protein-mediated oxidative stress,and deregulation of cellular signaling pathways by viral *** integration to promote genome instability is a feature of HBV infection,and metabolic reprogramming leading to steatosis is driven by HCV *** current review aims to provide a brief overview of HBV,HCV and HdV molecular biology,and highlight specific viral-associated oncogenic mechanisms and common molecular pathways deregulated in HCC,and current as well as emerging treatments for HCC.

关键词： Chronic viral infection Hallmarks of cancer Hepatocellular carcinoma Hepatitis B virus Hepatitis C virus Hepatitis delta virus co-infection Molecular mechanisms Viral hepatitis

Beginning from the end:the presynaptic terminal as a pathomechanism hub in frontotemporal dementia and amyotrophic lateral sclerosis

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Neural regeneration research 2025年第11期20卷 3217-3218页

作者： laura Huggon Emma l.Clayton UK dementia research Institute at King’s College london LondonUK department of Basic and Clinical Neuroscience Institute of Psychiatry Psychology&NeuroscienceKing’s College LondonLondonUK

Frontotemporal dementia and amyotrophic lateral sclerosis:Frontotemporal dementia(F T d)and amyo t rophic lateral sclerosis(AlS)are neurodegenerative diseases with significant overlapping *** these neurodegenerative diseases affect different neuronal populations(with FTd affecting neurons of the frontal and temporal lobes,and AlS affecting upper and lower motor neurons),these two diseases are complexly *** and AlS exist on a disease spectrum,with shared genetic causes,clinical presentations,and pathologies.

关键词： diseases amyotrophic sclerosis

The role of gut microbiota in the gut-brain axis:current challenges and perspectives

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Protein & Cell 2013年第6期4卷 403-414页

作者： Xiao Chen roshan d’souza Seong-Tshool Hong Bdrd research Institute JINIS Biopharmaceuticals Inc948-9 DunsanBongdongWanjuChonbuk 565-902South Korea department of Microbiology and Genetics and Institute for Medical Science Chonbuk National University Medical SchoolJeonju 561-712South Korea

Brain and the gastrointestinal(GI)tract are intimately con-nected to form a bidirectional neurohumoral communica-tion *** communication between gut and brain,knows as the gut-brain axis,is so well established that the functional status of gut is always related to the condi-tion of *** researches on the gut-brain axis were traditionally focused on the psychological status affecting the function of the GI ***,recent evidences showed that gut microbiota communicates with the brain via the gut-brain axis to modulate brain development and behavioral *** recent fi ndings on the new role of gut microbiota in the gut-brain axis implicate that gut microbiota could associate with brain functions as well as neurological diseases via the gut-brain *** elucidate the role of gut microbiota in the gut-brain axis,precise identification of the composition of microbes constituting gut microbiota is an essential ***,identifi cation of microbes constituting gut microbiota has been the main technological challenge currently due to massive amount of intestinal microbes and the diffi culties in culture of gut *** methods for identifi ca-tion of microbes constituting gut microbiota are depend-ent on omics analysis methods by using advanced high tech ***,we review the association of gut microbiota with the gut-brain axis,including the pros and cons of the current high throughput methods for identi-fi cation of microbes constituting gut microbiota to eluci-date the role of gut microbiota in the gut-brain axis.

关键词： gut microbiota the gut-brain axis central nervous system high throughput methods next-generation sequencings