检索结果-南通市图书馆

chinese Chemical Letters 2004年第12期15卷 1395-1396页

作者： Qian LIU Gang FANG Li Ping wu Jian Mei CUI Xiao Tian LIANG song wu institute of materia medica, peking union medical college & chinese academy of medical sciences, beijing 100050 institute of materia medica Peking Union Medical College Chinese Academy of Medical Sciences Beijing 100050 China

A stereoselective and economic synthesis of the carbapenem sidechain (2S, 4S)-4-ace-tylsulphanyl-2-[(S)1-phenylethyl-carbamoyl] pyrrolidine-1-carboxylic acid 4-nitrobenzylester was developed. Due to the effect of spatial hindrance, only the (2S,4S) diastereomer 3 wasobtained by coupling 1 and the inexpensive racemic 2 catalyzed by EEDQ.

关键词： Stereoselective synthesis carbapenem sidechain acylation.

Study of Intramolecular Cyclization of N-styryl-oxo-cinnamides (Ⅱ)

在线全文

学校读者我要写书评

暂无评论

chinese Chemical Letters 1998年第3期9卷 235-236页

作者： Nian Chun MA Ke Mei wu and Liang HUANG(institute of materia medica chinese academy of medical sciences,peking union medical college, beijing 100050) institute of materia medica Chinese Academy of Medical Sciences Peking Union Medical College Beijing 100050 China

The preparations and intramolecular cyclizations of amides 5, (N-methyl-N-(2 - trans-2-phenylethenyl)-3-phenyl-2, 3-cis-oxiranecarboxamide) and 8, (N-methyl-N-(2-cis-2-phenylethenyl ) - 3 -pheny 1-2, 3 - cis -oxiranec... 详细信息

关键词： intramolecular cyclization cis-oxirane cis-ene trans-ene

Studies on Agarofurans Ⅰ. New Synthesis of Nor-Ketoagarofuran and 4-Hydroxydihydroagarofuran

在线全文

学校读者我要写书评

暂无评论

chinese Chemical Letters 1997年第1期8卷 25-26页

作者： wu-Yan ZHANG Ji Yu GUO Xiao Tian LIANG(institute of materia medica, chinese academy of medical sciences &peking union medical college, beijing 100050) institute of materia medica Chinese Academy of Medical Sciences Peking Union Medical College Beijing 100050 China

Nor-ketoagarofuran (1), one of the furanoids isolated from grnd Oil, has been Synthesed in a preprative scale in high yield from olefin 3 in 3 steps. Reaction of norketoagarofuran (1) with CH3MgI afforded 4 (2), an an... 详细信息

关键词： KBr Studies on Agarofurans New Synthesis of Nor-Ketoagarofuran and 4-Hydroxydihydroagarofuran

Studies on Agarofurans Ⅲ. The Synthesis of 3-Substituted Agarofurans

在线全文

学校读者我要写书评

暂无评论

chinese Chemical Letters 2000年第4期11卷 301-304页

作者： wu Yan ZHANG Ji Yu GUO Xiao Tian LIANG (institute of materia medica. chinese academy of medical sciences & peking union medical college, beijing 100050) institute of materia medica Chinese Academy of Medical Sciences Peking Union Medical College Beijing 100050 China

14-Nor-3-oxodihydroagarofuran (2) was prepared in high yield. From 2, derivatives12 and 13 were synthesized by Grignard addition. In order to identify the configuration of C-3 in compound 12 and 13, the sterospecific ... 详细信息

关键词： Agarofuran synthesis

Studies on Agarofurans Ⅳ. The Synthesis of 4-Substitutioned Agarofurans

在线全文

学校读者我要写书评

暂无评论

chinese Chemical Letters 2000年第5期11卷 399-400页

A new synthetic route for α -agarofuran(1b) is described. Several agarofuran derivatives were synthesized in similar way. Derivative 1d was also synthesized in a novel way, in which the substitution at C-4 was perfor... 详细信息

关键词： Agarofuran synthesis.

The Chemical Reactions of 11-Hydroxycephalotaxine

在线全文

学校读者我要写书评

暂无评论

chinese Chemical Letters 2000年第6期11卷 489-492页

作者： Chuan Pin ZOU Ke Mei wu Liang HUANG (institute of materia medica, chinese academy of medical sciences,peking union medical college, beijing 10050) institute of materia medica Chinese Academy of Medical Sciences Peking Union Medical College Beijing 10050 China

Some of the chemical reactions of 11-hydroxycephalotaxine 1, which were encountered during the derivation of 1 and the related compounds were reported.

关键词： 11-hydroxycephalotaxine structural modification

AN　ATTEMPT　TO　SYNTHESIZE　HOMOCLAUSENAMIDE　AND　ZETACLAUSENAMIDE　－Study　of　The　Intramolecular　Cyclization

在线全文

学校读者我要写书评

暂无评论

chinese Chemical Letters 1996年第8期7卷 706-708页

作者： Nian Chun MA Ke Met wu and Liang HUANG(institute of materia medica. chinese academy of medical sciences.peking union medical college. beijing 100050, China) institute of materia medica Chinese Academy of Medical Sciences Peking Union Medical College Beijing 100050 China

Preliminary studies on the intramolecular cyclization of amides 11 and 15 in anatlempl to synthesize the natural Producls homoclausenamide 1 and zetaclausenamide 2 werereported.

关键词： homoclausenamide zetaclausenamide,intramofecular cyclization

Studies on the Reaction of Substituted 6-Nitrocoumarin with Anilines

在线全文

学校读者我要写书评

暂无评论

chinese Chemical Letters 1999年第10期10卷 811-812页

作者： Long Fei XIE Shi Ping XU song XU Lan Min LI(institute of materia medica, chinese academy of medical sciencesand peking union medical college, beijing 100050) institute of materia medica Chinese Academy of Medical Sciences Peking Union Medical College Beijing 100050 China

3-Acetyl-7-hydroxy-8-methyl-6-nitrocoumarin reacted with substituted anilines, and fission of the heterocyclic ring occurred.

关键词： 6-nitrocoumarin heterocyclic ring fission Schiff base hydrazone

New Stereoselective Synthesis of 4-Butyl-α-agarofuran

在线全文

学校读者我要写书评

暂无评论

chinese Chemical Letters 2003年第9期14卷 881-882页

作者： Chun LI, Da Li YIN, Hui Qin HUANG, Xiang Hong wu, Ji Yu GUOinstitute of materia medica, chinese academy of medical sciences & peking union medical college, beijing 100050 institute of materia medica Chinese Academy of Medical Sciences Peking Union Medical College Beijing 100050 China

A potent anxiolytic 4-butyl-α-agarofuran (AF-5) was synthesized from (+)dihydro-carvone. Acid catalyzed hydration of (+)dihydrocarvone and interconversion with β-O-ketone 8 and the key intermediate α,β-unsaturated... 详细信息

关键词： AF-5 stereoselective synthesis.

Intramolecular Induction of Asymmetric Darzen's Condensation of Aldehydes with Chiral α-Chloroacetates

在线全文

学校读者我要写书评

暂无评论

chinese Chemical Letters 1999年第6期10卷 441-442页

作者： Guo Bin HUANG Gan Feng CAO Ke Met wu Liang HUANG(institute of materia medica. chinese academy of medical sciences & peking union medical college.Xian Nong Tan Street. beijing 100050) institute of materia medica Chinese Academy of Medical Sciences Peking Union Medical College 1 Xian Nong Tan Street Beijing 100050 China

The asymmetric Darzen's condensation of aldehydes with a-chloroacetates of somenaturally occurring or synthetic chiral alcohols was described. The de% of products fell over therange of 4. 78% to 99%.

关键词： Asymmetric Darzen's condensation chiral α-chloroacetates