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Brief potentially ictal rhythmic discharges on intraoperative electrocorticography predict a good outcome of focal cortical dysplasia after surgical resection: a case report

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Acta Epileptologica 2023年第3期6卷 163-167页

作者： sofía s.sánchez‑Boluarte Wilfor Aguirre‑Quispe Manuel Herrera Aramburú William O.Tatum Walter De La Cruz Ramírez school of Medicine Cesar Vallejo UniversityAv.Victor LarcoTrujilloTrujillo 1770Peru Departamento de Epilepsia Instituto Nacional de Ciencias NeurológicasJr.Ancash 1271LimaLima 15001Peru Neurosciences Clinical Effectiveness and Public Health Research GroupUniversidad Científica del SurPanamericana Sur 19Villa EL SalvadorLimaLima 15067Peru Department of Neurology Mayo ClinicMangurian Bldg.Fourth Floor4500 San Pablo RoadFL 32224 JacksonvilleUSA

Background Focal cortical dysplasia(FCD)is a common cause of drug-resistant ***(EEG)biomarkers that predict good postoperative outcomes are essential for identifying patients with focal *** presentation We report the case of a 21-year-old female with seizure onset at the age of 9,characterized by left-hand dystonic posturing and impaired awareness,which evolved to bilateral tonic-clonic seizures,evaluated in a neurological referral center in Lima,*** 6-h video-EEG,interictal EEG revealing focal brief potentially ictal rhythmic discharges(BIRDs)over the right frontal central region,lasting less than 10 *** ictal features were characterized by low-voltage fast activity over the same *** magnetic resonance imaging(MRI)demonstrated a focal lesion of focal cortical dysplasia type II in the right frontal *** patient underwent a lesionectomy guided by electrocorticography,which showed continuous *** showing a brief burst of spikes lasting longer than 0.5 s,were also identified on intraoperative electrocorticography(ECoG)and helped define the extent of *** patient obtained an Engel Outcome Class IA at 6 years of *** The atypical BIRDs on ECoG can be used as a prognostic biomarker for prolonged seizure-freedom outcome in patients with *** reports are needed in developing countries with and without brain MRI lesions to advance outpatient presurgical evaluations despite limited resources.

关键词： Electrocorticography Cortical dysplasia-focal epilepsy syndrome Drug-resistant epilepsy Frontal lobe epilepsy

Reinforcement of Thermoplastic starch Films with Cellulose Fibres Obtained from Rice and Coffee Husks

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Journal of Renewable Materials 2018年第6期6卷 599-610页

作者： sofía Collazo-Bigliardi Rodrigo Ortega-Toro Amparo Chiralt Boix Instituto de Ingeniería de Alimentos para el Desarrollo Universitat Politècnica de ValènciaCamino de Vera s/n46022 ValenciaSpain Programa de Ingeniería de Alimentos Facultad de IngenieríaUniversidad de CartagenaCarrera 6#36-100Cartagena de Indias D.T y CColombia

Cellulosic fibres from coffee(CF)and rice(RF)husks have been obtained applying chemical treatments and characterized as to their microstructure and thermal *** materials have been incorporated into glycerol plasticised thermoplastic starch(TPs)films obtained by melt blending and compression moulding at 1 wt%,5 wt%and 10 wt%.Microstructure,thermal behaviour and optical,tensile and barrier properties of the composites were *** kinds of micro-fibres improve the film stiffness while reduced the film ***,CF better maintained the film ductility at 1 and 5 wt%.A network of fine oriented fibres was observed on the surface of the films,while internal fibres exhibited a good adherence to the polymer *** water vapour permeability of TPs films was not reduced in composites,although oxygen permeability was lowered by about 17%.Film transparency decreased by fibre addition in the UVVIs *** stability of composites was slightly higher than net TPs films.

关键词： Cellulose fibres coffee husk reinforcing properties rice husk starch composites

Rheumatic manifestations of inflammatory bowel disease

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World Journal of Gastroenterology 2009年第44期15卷 5517-5524页

作者： Tatiana sofía Rodríguez-Reyna Cynthia Martínez-Reyes Jesús Kazúo Yamamoto-Furusho Department of Immunology and Rheumatology National Institute of Medical Sciences and Nutrition Salvador ZubiránVasco de Quiroga 15Col Sección XVI. DelTlalpanMexico City 14000Mexico Department of Gastro-enterology National Institute of Medical Sciences and Nutrition Salvador ZubiránVasco de Quiroga 15Col Sección XVI. DelTlalpanMexico City 14000Mexico

This article reviews the literature concerning rheu-matic manifestations of inflammatory bowel disease (IBD),including common immune-mediated pathways,frequency,clinical course and therapy. Musculoskel-etal complications are frequent and well-recognized manifestations in IBD,and affect up to 33% of pa-tients with IBD. The strong link between the bowel and the osteo-articular system is suggested by many clinical and experimental observations,notably in HLA-B27 transgenic rats. The autoimmune pathogenic mechanisms shared by IBD and spondyloarthropathies include genetic susceptibility to abnormal antigen pre-sentation,aberrant recognition of self,the presence of autoantibodies against specific antigens shared by the colon and other extra-colonic tissues,and increased intestinal permeability. The response against microor-ganisms may have an important role through molecular mimicry and other mechanisms. Rheumatic mani-festations of IBD have been divided into peripheral arthritis,and axial involvement,including sacroiliitis,with or without spondylitis,similar to idiopathic anky-losing spondylitis. Other periarticular features can oc-cur,including enthesopathy,tendonitis,clubbing,peri-ostitis,and granulomatous lesions of joints and *** and osteomalacia secondary to IBD and iatrogenic complications can also occur. The manage-ment of the rheumatic manifestations of IBD consists of physical therapy in combination with local injection of corticosteroids and nonsteroidal anti-inflammatory drugs; caution is in order however,because of their possible harmful effects on intestinal integrity,perme-ability,and even on gut inflammation. sulfasalazine,methotrexate,azathioprine,cyclosporine and lefluno-mide should be used for selected indications. In some cases,tumor necrosis factor-α blocking agents should be considered as first-line therapy.

关键词： Inflammatory bowel disease spondylitis Rheumatic diseases

Evaluation of sources and methods of pectin extraction from fruit and Vegetable wastes:A systematic Literature Review(sLR)

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Food Bioscience 2023年第1期51卷 1370-1379页

作者： Carolina sofía salazar Ripoll Gustavo Adolfo Hincapie-Llanos Universidad Pontificia Bolivariana MedellínAntioquiaColombia

The potentially commercial sources of pectin are *** have studied different extraction methods using a wide variety of fruits and vegetables to obtain pectins with better *** objective of this work was to identify the methods used in the extraction of pectin,the most used sources and the operation parameters that enable the achievement of higher yields and the final characteristics of the obtained *** are based on bibliometric methods for exploring the structure of knowledge in this field for the last twelve *** this end,a systematic Literature Review(sLR)using the sCOPUs database was carried out,which allowed identifying keywords and formulating search equations to find scientific articles on the topic in *** selecting the articles,a detailed reading of these works was carried out,and the used extraction methods and the evaluated variables,yields and characteristics were *** article compares and discusses the effects of conventional and non-conventional pectin extraction techniques,which may provide valuable information on sources and alternatives for pectin extraction to ease decision-making in future *** acid hydrolysis method remains the most widely used pectin extraction technique since it provides higher *** is followed by microwave-assisted extraction,ultrasonic extraction,and the enzymatic method,which have a greater capacity to deliver pectins with high methoxyl ***,non-conventional methods such as radiofrequency,ohmic heating,and aqueous two-phase extraction are presented as promising techniques that offer pectins with a high degree of esterification in addition to good yields.

关键词： Agro-industrial wastes Acid hydrolysis Microwave Ultrasound Degree of esterification Galacturonic acid

Unexpected bonds:ubiquitin-like conjugation of cGAs/CDNTases supports their enzymatic activity and antiphage defense

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signal Transduction and Targeted Therapy 2023年第9期8卷 3899-3901页

作者： Katarzyna Andryka-Cegielski sofía soler Eva Bartok Institute of Experimental Haematology and Transfusion Medicine University HospitalUniversity of BonnBonnGermany Institute of Clinical Chemistry and Clinical Pharmacology University HospitalUniversity of BonnBonnGermany

In their recently published study in Nature,Jenson et al.1 provide compelling,unexpected evidence that bacterial cGAMP synthase(cGAs)and other cGAs/DncV-like Nucleotidyltransferases(CD-NTase)undergo ubiquitin-like conjugation(ULC)in type-II cyclic-oligonucleotide-based anti-phage signaling systems(CBAss).cGAs conjugation promotes cyclic-nucleotide(CN)formation and thus antiphage ***,the authors also reveal a new class of phage-encoded CBAss inhibitor,T4 Vs.4,a CN-sponge which limits CBAss effector function and promotes phage replication,revealing another weapon in the“arms race”between phages and their bacterial hosts.

关键词： bonds enzymatic sponge

Fatal and non-fatal injuries due to suspension trauma syndrome: A systematic review of definition, pathophysiology, and management controversies

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World Journal of Emergency Medicine 2021年第4期12卷 253-260页

作者： Patrizio Petrone sofía Espinoza-Villalobos Gerard ABaltazar Kjetil søreide Adam stright Collin E.M.Brathwaite D’Andrea K.Joseph Department of surgery NYU Long Island School of MedicineNYU Langone Hospital–Long IslandMineola 11501USA 2 Department of Gastrointestinal SurgeryStavanger University HospitalStavanger 4011Norway

BACKGROUND: suspension trauma syndrome is a life-threatening event that occurs when a person is "trapped" in a prolonged passive suspension. It is most commonly seen in people who engage in occupational or sport activities that require harness suspension. The aim of this study is to identify the predisposing factors, pathophysiology, and management of suspension ***: A review and analysis of the literature published in English and spanish from 1972 to 2020 on suspension trauma were performed. search sources were Pub Med, Medline, Cochrane Library, MesH, Up To Date, and Google scholar. Articles referring to suspension trauma associated with other injury mechanisms(traumatic impact injuries, drowning, asphyxiation, or bleeding), case reports, and pediatric population were ***: Forty-one articles were identified. Of these, 29 articles related to mechanism, pathophysiology, and management of individuals who suffered prolonged suspension trauma without associated traumatic injuries were included in the study. We encountered several controversies describing the putative pathophysiology, ranging from blood sequestration in the lower extremities versus accumulation of metabolic waste and hyperkalemia to dorsal hook-type harness as a trigger cause of positional asphyxia;to vascular compression of femoral vessels exerted by the harness causing decreased venous return. Pstients suspended in a full-body harness with dorsal hook showed more hemodynamic alterations in response to the compressive effect on the rib cage, causing a reduction in perfusion by presenting a decrease in pulse pressure. Management strategies varied across ***: Progress has been made in individualizing the population at risk and in the management of suspension trauma. We recommend the formation of consensus definitions, larger cohort or registry studies to be conducted, and experimental animal models to better understand the mechanisms in order to develop management

关键词： suspension trauma Reflux syndrome suspension trauma syndrome Harness suspension

Uncertainties in the Mercury Mass Balance in a Coal-Based IGCC Power Plant (Puertollano, spain)

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Energy Engineering 2021年第4期118卷 1223-1235页

作者： José María Esbrí Alba Martinez-Coronado sofía Rivera Jurado Eva García-Noguero Pablo Higueras Instituto de Geología Aplicada(UCLM) Pl.Manuel Meca1Ciudad Real13400Spain

Mercury(Hg)is a global pollutant that is subject to strict regulations to reduce anthropogenic *** production of energy represents an important activity that leads to Hg emissions into the *** all the systems used,IGCC plants are the most promising for reducing Hg emissions,since it is possible to remove Hg from syngas prior to *** aim of the present work was to evaluate the presence of Hg in the main streams of an experimental IGCC plant(ELCOGAs,Puertollano)in order to quantify Hg emissions and investigate the possibility of reducing *** main streams of the system were sampled for three consecutive days and both the solids,i.e.,raw material(coal and petroleum coke),fine and coarse slags,fly ash,sulphur,and the liquids,i.e.,slag system,Venturi scrubber and saturator,were *** results show that an average of 12.9%of the Hg that enters the IGCC power plant is eliminated with solid waste and only 0.08%with liquid *** is still an average of 87.12%of Hg that is not accounted for in the mass balance and that could remain in the system and/or be eliminated in the streams that were not *** it is impossible to offer an explanation for the final fate of the Hg lost in the system based on the obtained results,the data suggest that sulphur byproducts could be primarily responsible for the elimination of Hg from the syngas,and that a major proportion of Hg should be emitted via the chimney after the syngas combustion process.

关键词： Mercury IGCC power plant mass-balance hypercinnabar

Behavior of the Cultivable Airborne Mycobiota in air-conditioned environments of three Havanan archives, Cuba

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Journal of Atmospheric science Research 2020年第1期3卷 16-28页

作者： sofía Borrego Alian Molina Preventive Conservation Laboratory National Archive of the Republic of CubaCompostela 906 esquina a calle San IsidroPO Box:10100La Habana ViejaHavanaCuba

High concentrations of environmental fungi in the archives repositories are dangerous for the documents preserved in those places and for the workers'*** aims of this work were to evaluate the behavior of the fungal concentration and diversity in the indoor air of repositories of 3 archives located in Havana,Cuba,and to demonstrate the potential risk that these taxa represent for the documentary heritage preserved in these *** indoor and outdoor environments were sampled with a *** the I/O ratios,it was evident that two of the studied archives were not contaminated,while one of them did show contamination despite having temperature and relative humidity values very similar to the other ***,Penicillium and Cladosporium were the predominant genera in the indoor *** finds for archival environments were the genera Harposporium and *** principal species classified ecologically as abundant were *** and *** are known as opportunistic pathogenic *** the analyzed taxa excreted acids,the most of them degraded cellulose,starch and gelatin while about 48%excreted different *** 33%of them showed the highest biodeteriogenic potential,evidencing that they are the most dangerous for the documentary collections.

关键词： Archives Environmental fungi Indoor environments Microbial quality of archive environments Quality of indoor environments Documentary biodeterioration

Effect of Fe_(3)O_(4) nanoparticles on magnetic xerogel composites for enhanced removal of fluoride and arsenic from aqueous solution

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Water science and Engineering 2022年第4期15卷 305-317页

作者： sasirot Khamkure Victoria Bustos-Terrones Nancy Jakelin Benitez-Avila María Fernanda Cabello-Lugo Prócoro Gamero-Melo sofía Esperanza Garrido-Hoyos Juan Marcos Esparza-schulz Postgraduate Department National Council for Science and Technology(CONACyT)-Mexican Institute of Water TechnologyMorelos 62574Mexico Department of Environmental Technology Engineering Polytechnic University of the State of MorelosMorelos 62550Mexico Department of sustainability of Natural Resources and Energy Center for Research and Advanced Studies of the National Polytechnic InstituteCoahuila 25900Mexico Department of Chemistry Metropolitan Autonomous University Campus IztapalapaMexico City 09340Mexico

Fe_(3)O_(4)magnetic xerogel composites were prepared by polycondensation of resorcinol(R)-formaldehyde reaction via a sol-gel process in an aqueous solution through varying the molar ratio of Fe_(3)O_(4)nanoparticles(MNPs),catalyst(C),and water(W)*** were obtained by co-precipitation(MC),oxidation of iron salts(MO),or solvothermal synthesis(Ms).Both MNPs and magnetic xerogels were examined regarding the performance of arsenic and fluoride removal in a batch *** MC-based MNPs had higher adsorption capacities for both fluoride(202.9 mg/g)and arsenic(3.2 mg/g)than other MNPs in optimum *** X-ray diffraction,Fourier transform infrared spectroscopy,and energy-dispersive X-ray spectroscopy confirmed that Fe was composed into the polymeric matrix of magnetic xerogels that contained 0.59%-4.42%of Fe with a molar ratio of MNPs(M)to R between 0.01 and *** low R/C and optimum M/R ratios,an increase in the surface area of magnetic xerogels affected the fluoride and arsenic adsorption *** magnetic xerogel composites with the MC-based MNPs prepared at a fixed R/C ratio(100)and at different R/W(0.05-0.06)and M/R(0.07-0.10)ratios had a high arsenic removal efficiency of 100%at an As(V)concentration of 0.1 mg/L and pH of *** maximum adsorption capacities of magnetic xerogels were approximately five times higher than those of the xerogels without MNP ***,Fe_(3)O_(4)nanoparticles enhanced the adsorption of arsenate and *** variations of alkaline catalyst and water content significantly affected the resulting properties of textural and surface chemistry of magnetic xerogel composites.

关键词： Adsorption Arsenic Fluoride Composite Magnetite nanoparticles Xerogel