Brief potentially ictal rhythmic discharges on intraoperative electrocorticography predict a good outcome of focal cortical dysplasia after surgical resection: a case report
作者机构：School of MedicineCesar Vallejo UniversityAv.Victor LarcoTrujilloTrujillo 1770Peru Departamento de EpilepsiaInstituto Nacional de Ciencias NeurológicasJr.Ancash 1271LimaLima 15001Peru NeurosciencesClinical Effectiveness and Public Health Research GroupUniversidad Científica del SurPanamericana Sur 19Villa EL SalvadorLimaLima 15067Peru Department of NeurologyMayo ClinicMangurian Bldg.Fourth Floor4500 San Pablo RoadFL 32224 JacksonvilleUSA
出 版 物：《Acta Epileptologica》 (癫痫学报（英文）)
年 卷 期：2023年第6卷第3期
页 面：163-167页
学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学]
基 金：National Institute of Neurological Sciences
主 题：Electrocorticography Cortical dysplasia-focal epilepsy syndrome Drug-resistant epilepsy Frontal lobe epilepsy
摘 要：Background Focal cortical dysplasia(FCD)is a common cause of drug-resistant ***(EEG)biomarkers that predict good postoperative outcomes are essential for identifying patients with focal *** presentation We report the case of a 21-year-old female with seizure onset at the age of 9,characterized by left-hand dystonic posturing and impaired awareness,which evolved to bilateral tonic-clonic seizures,evaluated in a neurological referral center in Lima,*** 6-h video-EEG,interictal EEG revealing focal brief potentially ictal rhythmic discharges(BIRDs)over the right frontal central region,lasting less than 10 *** ictal features were characterized by low-voltage fast activity over the same *** magnetic resonance imaging(MRI)demonstrated a focal lesion of focal cortical dysplasia type II in the right frontal *** patient underwent a lesionectomy guided by electrocorticography,which showed continuous *** showing a brief burst of spikes lasting longer than 0.5 s,were also identified on intraoperative electrocorticography(ECoG)and helped define the extent of *** patient obtained an Engel Outcome Class IA at 6 years of *** The atypical BIRDs on ECoG can be used as a prognostic biomarker for prolonged seizure-freedom outcome in patients with *** reports are needed in developing countries with and without brain MRI lesions to advance outpatient presurgical evaluations despite limited resources.
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