检索结果-南通市图书馆

Autophagy in neuroinflammation after traumatic brain injury

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第5期19卷 951-952页

作者： Chinmoy sarkar Marta M.Lipinski Shock Trauma and Anesthesiology Research(STAR)CenterDepartment of AnesthesiologyUniversity of Maryland School of MedicineBaltimoreMDUSA Department of Anatomy and Neurobiology University of Maryland School of MedicineBaltimoreMDUSA

Traumatic brain injury(TBI)is an acquired injury of the brain caused by the impact of external forces on the brain(Maas et al.,2008).It is a major cause of death and disability among people of all ages(Maas et al.,2008).The primary mechanical injury to the brain initiates a cascade of secondary biochemical events that lead to acute and chronic neurodegeneration and activation of inflammatory pathways(Maas et al.,2008).Both brain-resident microglia and blood-derived myeloid cells-macrophages and monocytes that infiltrate the brain due to injury-induced blood-brain barrier damage,contribute to the inflammatory responses after TBI(Morganti et al.,2015).

关键词： damage death after

N-acetyl-L-leucine: a promising treatment option for traumatic brain injury

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2022年第9期17卷 1957-1958页

Traumatic brain injury(TBI)is a mechanical injury to the brain,which can be sustained due to falls,accidents,contact sports or in combat *** is a serious health problem-affecting people of all ages *** per the recent epidemiological study,more than 55 million people suffer from TBI annually(GBD 2016 Traumatic Brain Injury and Spinal Cord Injury Collaborators,2019),and its prevalence has increased by almost 8.4%between 1990 and 2016(GBD 2016 Traumatic Brain Injury and Spinal Cord Injury Collaborators,2019).Depending on severity,TBI can lead to premature death and disability.

关键词： sustained Traumatic injury

Infrared Spectra of PH3 and NF_(3): An Algebraic Approach

在线全文

学校读者我要写书评

暂无评论

Chinese Physics Letters 2013年第7期30卷 9-12页

作者： Joydeep Choudhury Nirmal Kumar sarkar Ramendu Bhattacharjee Department of Physics Assam UniversitySilchar-788011India Department of Physics Karimganj CollegeKarimganj-788710India

Molecular spectroscopy is a branch of physics which deals with the interaction of electromagnetic radiation with *** the new theoretical approach,i.e.,Lie algebraic approach,we calculate the infrared spectra of phosphine in the range from 3000 cm^(-1) to 9500 cm^(-1) and nitrogen trifluoride in the range from 900 cm^(-1) to 4500 cm^(-1).The model Hamiltonian constructed seems to describe the P–H and N–F stretching modes accurately with only four numbers of *** present calculation not only predicts the higher overtones but also shows good agreement with the few observed data.

关键词： parameters. Infrared stretching

Improved indoor environment through optimised ventilator and furniture positioning:A case of slum rehabilitation housing,Mumbai,India

在线全文

学校读者我要写书评

暂无评论

Frontiers of Architectural Research 2020年第2期9卷 350-369页

作者： Ahana sarkar Ronita Bardhan Centre for Urban Science and Engineering Indian Institute of Technology BombayMumbai 400076India The Martin Centre for Architectural and Urban Studies Department of ArchitectureUniversity of CambridgeCambridgeCB21PXUnited Kingdom

This study optimized the ventilator and furniture location of a tenement unit in a low-income urban habitat to obtain maximum experiential indoor environmental quality(e-IEQ)over the breathing *** interior layouts using a combination of the two design parameters of ventilator location and bed position were generated for optimizing the design *** layout could promote maximum indoor airflow and minimum indoor air temperature and contaminant *** this study,an improved indoor environment is hypothesized to be attainable through improved natural ventilation and thermal performance in the occupied zones.A sequential methodology involving“parametric design modeling ecomputational simulationemultiobjective optimizationemulticriteria decision making”-based framework was *** exhibited that the currently designed tenement unit had a poor indoor environment,whereas the hypothesized iterated layout“optimized design layout,scenario 3(ODL 3)”derived from the optimization and decision-making algorithm performed effectively in providing *** increase in experiential indoor air velocity by 0.2 m/s and a decrease in temperature by 2C were observed over the monitoring point in the ODL 3 considering the existing ***,this study can find a way toward the development of sustainable habitat design guidelines under upcoming slum redevelopment policies across the nation.

关键词： Ventilator Furniture layout Low-income tenement Indoor environmental quality(IEQ) Computational fluid dynamics(CFD) Multiobjective multicriteria decision making(MCDM)optimization

Acanthus leucostachyus leaf extracts promote excision wound healing in mice

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Biomedicine 2022年第11期12卷 475-482页

作者： Deepjyoti Dev Ashish sarkar Bishnupada Roy Parasitology and Toxicology Laboratory Department of ZoologyNorth-Eastern Hill UniversityShillong-793022MeghalayaIndia

Objective:To evaluate the in vivo wound healing activity of Acanthus leucostachyus leaf extracts using an excision wound model in ***:Mice were divided into two groups of six animals in each group:the control group and the Acanthus leucostachyus extract-treated *** potential was evaluated by determination of physical parameters(contraction rate,epithelialization period,and tensile strength),biochemical parameters(protein,DNA,and hydroxyproline content),the expression of growth factor and pro-inflammatory cytokines,as well as histological and ultrastructural ***:Treatment with Acanthus leucostachyus leaf extracts markedly increased the rate of wound contraction,tensile strength,the concentrations of protein,DNA,and hydroxyproline,and the expression of growth factor,as well as promoted epithelialization,compared to the *** addition,Acanthus leucostachyus leaf extracts significantly reduced the expression of pro-inflammatory *** and ultrastructural studies revealed the presence of thicker epithelial layer and smoother surface topography in the extract-treated group compared to the ***:Acanthus leucostachyus leaf extracts show potent wound-healing activity and can be used as a wound healing agent.

关键词： Chronic wounds Acanthus leucostachyus Epithelialization period Tensile strength Hydroxyproline Pro-inflammatory cytokine Wound healing

Hydromagnetic oscillatory Couette flow in rotating system with induced magnetic field

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2014年第10期35卷 1331-1344页

作者： G.S.SETH S.M.HUSSAIN S.sarkar Department of Applied Mathematics Indian School of Mines Department of Mathematics O.P.Jindal Institute of Technology

This paper presents a study of hydromagnetic Couette flow of an incompress- ible and electrically conducting fluid between two parallel rotating plates, one of which is oscillating in its own plane. A uniform transverse magnetic field is used, and the induced magnetic field is taken into account. The exact solution to the governing equations is obtained in a closed form. The solution to the problem in the case of vanishing and small finite magnetic Prandtl numbers is also derived from the general solution. The asymp- totic behavior of the solution for large values of the frequency parameter is analyzed to gain some physical insights into the flow pattern. Expressions for the shear stress at both the oscillatory and stationary plates due to primary and secondary flows and mass flow rate in the primary and secondary flow directions are also obtained. The results of the fluid velocity and the induced magnetic field are presented. The shear stresses on the plates due to the primary and secondary flows and the corresponding mass flow rates are presented in a tabular form.

关键词： magnetic interaction parameter Ekman number frequency parameter,hydromagnetic Stokes-Ekman boundary layer magnetic diffusion boundary layer

在线全文

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Biomedicine 2024年第8期14卷 319-330页

作者： Priya Bhardwaj Swarnabha sarkar Ritu Mishra Department of Pharmacology All India Institute of Medical SciencesNew Delhi-110029India Department of Physiology All India Institute of Medical SciencesNew Delhi-110029India Department of Zoology University of AllahabadPrayagrajUttar Pradesh-211002India

The recently re-emerged mpox(monkeypox)virus that causes mpox disease is a member of genus Orthopoxvirus and has unprecedentedly spread *** studies have contributed to our understanding of its evolution,pathophysiology,and clinical *** current outbreak of the mpox virus depicts its novel route of transmission as a new ***,the exact reason for its transition from an epidemic to a pandemic remains ***,other poxviruses such as vaccinia virus,variola virus,and cowpox virus,also belong to the same genus,*** the present review,our objective was to summarize the evidence on evolution,pathophysiology,and clinical manifestations of mpox virus and its related *** present review would aid in a better understanding of the current circulating mpox virus and its differences from other *** addition,the shared genetic factors contributing to virulence in these Orthopoxvirus highlight their evolutionary connections and genetic *** they exhibit differences in virulence,studying these genetic relationships is crucial for understanding their biology,pathogenicity,and the development of effective vaccines and antiviral therapeutics to curb mpox disease.

关键词： Evolution Mpox Orthopoxviruses Pathophysiology Poxviruses Transmission

Efficient MAC Protocols for Brain Computer Interface Applications

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2021年第10期69卷 589-605页

作者： Shams Al Ajrawi Ramesh Rao Mahasweta sarkar Department of Electrical and Computer Engineering San Diego State UniversitySan DiegoCAUSA Department of Electrical Engineering University of CaliforniaSan DiegoLa JollaCAUSA

Brain computer interface(BCI)systems permit individuals with motor disorders to utilize their thoughts as a mean to control external *** is a promising interdisciplinary field that gained the attention of many ***,the development of BCI systems is facing several challenges,such as network *** Medium Access Control(MAC)Protocol is the bottle-neck of network *** are many MAC protocols that can be utilized for dependable transmission in BCI applications by altering their control ***,modifying these parameters is another source of concern due to the scarcity in knowledge about the effect of ***,there is still no instrument that can receive and actualize these parameters on transmitters embedded inside the *** this paper,we propose two novel MAC protocols using passive UHF-RFID,the proposed protocols provide efficient and reliable communication between the transmitters and the *** UHF-RFID transmitters were used because they are energy efficient which makes them compatible with BCI *** first protocol is designed for the EEG *** the second protocol was designed for the ECoG *** evaluation results showed the validity of the proposed protocols in terms of network *** results also proved that the protocols are suitable and reliable for designing efficient BCI applications.

关键词： Brain-computer interface MAC protocol UHF-RFID TDMA FDMA CSMA

Dual response of graphene-based ultra-small molecular junctions to defect engineering

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2016年第5期9卷 1480-1488页

作者： Kunpeng Dou Xiaoxiao Fu Abir De sarkar Ruiqin Zhang Department of Physics and Materials Science City University of Hong Kong Hong Kong China Institute of Nano Science and Technology (An Autonomous Institute of Department of Science and Technology Government of India)Habitat Centre (Transit Campus) Phase X Sector-64 Mohali Punjab- 160 062 India

It has been reported that N and B doping induce a quasi-bound state that suppresses the conduction in graphene nanoribbon （GNR）-based junctions, while an H defect or a pyridine-like N-atom （PN） substitution at the edge of the GNR does not affect the transmission close to the Fermi energy. However, these results may vary when the size of the functional unit of the GNR junction decreases to a molecular level. In this study, a defect is introduced to a test-bed architecture consisting of a polyacene bridging two zigzag GNR electrodes, which changes the molecular state alignment and coupling to the electrode states, and varies the equivalence between two eigen-channels at the Fermi level. It is revealed that B and N atom substitution, and H defects play a dual role in the molecular conductance, whereas the PN substitution acts as an ineffective dopant. The results obtained from density functional theory combined with the non-equilibrium Green＇s function method aid in determining the optimal design for the GNR-based ultra-small molecular devices via defect engineering.

关键词： graphene defect electron transport molecular electronics single-molecule studies