Mpox and related poxviruses:A literature review of evolution,pathophysiology,and clinical manifestations
作者机构：Department of PharmacologyAll India Institute of Medical SciencesNew Delhi-110029India Department of PhysiologyAll India Institute of Medical SciencesNew Delhi-110029India Department of ZoologyUniversity of AllahabadPrayagrajUttar Pradesh-211002India
出 版 物：《Asian Pacific Journal of Tropical Biomedicine》 (亚太热带生物医学杂志（英文版）)
年 卷 期：2024年第14卷第8期
页 面：319-330页
核心收录：
学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学]
主 题：Evolution Mpox Orthopoxviruses Pathophysiology Poxviruses Transmission
摘 要：The recently re-emerged mpox(monkeypox)virus that causes mpox disease is a member of genus Orthopoxvirus and has unprecedentedly spread *** studies have contributed to our understanding of its evolution,pathophysiology,and clinical *** current outbreak of the mpox virus depicts its novel route of transmission as a new ***,the exact reason for its transition from an epidemic to a pandemic remains ***,other poxviruses such as vaccinia virus,variola virus,and cowpox virus,also belong to the same genus,*** the present review,our objective was to summarize the evidence on evolution,pathophysiology,and clinical manifestations of mpox virus and its related *** present review would aid in a better understanding of the current circulating mpox virus and its differences from other *** addition,the shared genetic factors contributing to virulence in these Orthopoxvirus highlight their evolutionary connections and genetic *** they exhibit differences in virulence,studying these genetic relationships is crucial for understanding their biology,pathogenicity,and the development of effective vaccines and antiviral therapeutics to curb mpox disease.
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