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Disseminated soft tissue diffuse large B-cell lymphoma involving multiple abdominal wall muscles:A case report

World Journal of Clinical Cases 2021年第28期9卷 8557-8562页

作者： Chang-Hoon Lee so-Yeon Jeon Ho-young Yhim Jae-Yong Kwak Department of Internal Medicine Jeonbuk National University Medical SchoolJeonju 54907South Korea

BACKGROUND Diffuse large B-cell lymphoma(DLBCL)is the most common subtype of non�Hodgkin lymphoma,and patients with DLBCL typically present rapidly growing *** involving muscle is rare and accounts for only 5%;furthermore,multiple muscles and soft tissue involvement of DLBCL is *** to unusual clinical manifestation,accurate diagnosis could be *** SUMMARY A 61-year-old man complained of swelling,pain and erythematous changes in the lower ***,soft tissue infection was suspected,however,skin lesion did not respond to antibiotics.18Fluoro-2-deoxy-D-glucose(18F-FDG)positron emission tomography-computed tomography demonstrated FDG uptake not only in the skin and subcutaneous tissue of the abdomen but also in the abdominal wall muscles,peritoneum,perineum,penis and *** was confirmed by biopsy of the abdominal wall muscle and subcutaneous *** intensive treatment including chemotherapy with rituximab,cyclophosphamide,doxorubicin,vincristine and prednisolone,central nervous system prophylaxis(intrathecal injection of methotrexate,cytarabine and hydrocortisone)and orchiectomy,he underwent peripheral blood stem cell mobilization for an autologous hematopoietic stem cell *** intensive treatment,the disease progressed rapidly and the patient showed poor outcome(overall survival,9 mo;disease free survival,3 mo).CONCLUSION The first clinical manifestation of soft tissue DLBCL involving multiple muscles was similar to the infection of the soft tissue.

关键词： Primary extranodal diffuse large B-cell lymphoma soft tissue lymphoma Disseminated muscles and soft tissue invasion Atypical presentation of diffuse large B�cell lymphoma Central nervous system relapse Case report

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The association between vitamin D levels and burn factors in different burn types

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Burns & Trauma 2020年第1期8卷 285-292页

作者： Yoon soo Cho Cheong Hoon Seo so young Joo Suk Hoon Ohn Department of Rehabilitation Medicine Burn CenterHangang Sacred Heart Hospital94-200 Yeongdeungpo-dongYeongdeungpo-guSeoul 07247Republic of Korea Department of Physical Medicine and Rehabilitation Hallym University Sacred Heart Hospital22 Gwanpyeong-ro 170 Beon-gil Dongan-gu Anyang Gyeonggi-do 14068Republic of Korea

Background:Patients with burns present with different clinical features depending on the types of burn injury and burn patients with lower levels of vitamin D have worse prognoses and more *** study aims to investigate the association between vitamin D levels and burn factors according to each burn type in relation to early intensive rehabilitation therapy initiated for inpatients with ***:In this retrospective study,we enrolled 757 of 1716 inpatients who underwent rehabilitative therapy between May 2013 and April *** types were divided into flame burn,electrical burn and other burns,including scalding,contact and chemical ***,burned body surface area(BSA),wound healing time(WHT),length of hospital stay(LOS)and body mass index were analysed between vitamin D deficient and non-deficient patient groups using Student’s ttests,or Mann-Whitney U test and among three burn types using one-way analysis of variance(ANOVA)or Kruskal-Wallis one-way *** relationship between vitamin D levels and burn factors was evaluated using Pearson’s or Spearman’s correlation coefficient tests,and multiple linear regression analysis in different burn ***:In total,88.9%patients were vitamin D deficient,and these patients had a larger burned BSA(p=0.015)and longer WHT and LOS(all psociated with vitamin D levels in all three burn types(psociated with vitamin D levels for inpatients with burns who had undergone rehabilitative *** burn patients with vitamin D deficiency,even those with a low burned BSA percentage,showed prol

关键词： Burn factors Vitamin D deficiency Burn type Wound healing time Rehabilitation

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Comparative study for predictability of type 1 gastric variceal rebleeding after endoscopic variceal ligation:High-frequency intraluminal ultrasound study

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World Journal of Clinical Cases 2021年第34期9卷 10566-10575页

作者： Jeong Hwan Kim Won Hyeok Choe Sun-young Lee so young Kwon In-Kyung Sung Hyung Seok Park Department of Internal Medicine Konkuk University School of MedicineKonkuk University Medical CenterSeoul 05030South Korea Department of Internal Medicine Konkuk University Medical CenterSeoul 143729South Korea Department of Internal Medicine Konkuk University School of MedicineSeoul 05030South Korea Department of Internal Medicine Digestive Disease CenterKonkuk University School of MedicineSeoul 05030South Korea

BACKGROUND The efficacy of endoscopic ultrasonography for the follow-up of gastric varices treated with endoscopic variceal ligation(EVL)has not been *** To evaluate the diagnostic correlation of esophagogastroduodenoscopy(EGD)and high-frequency intraluminal ultrasound(HFIUS)for type 1 gastric varices(GOV1)after EVL and to identify the predictability for rebleeding of EGD and *** In liver cirrhosis patients with GOV1,we performed endoscopic follow-up using EGD and HFIUS synchronously after EVL for hemorrhage from *** grading and red color signs were analyzed using EGD,and the largest variceal cross-sectional areas were measured using *** addition,1-year follow-up was *** rebleeding was defined as the presence of hematemesis,hematochezia,or melena without other evidence of bleeding on endoscopic *** In 26 patients with GOV1,variceal cross-sectional areas on HFIUS of GOV1 was poorly correlated with EGD grading of GOV1(r=0.36).In 17 patients who completed the 1-year follow-up,variceal cross-sectional areas on HFIUS was a good predictor of subsequent rebleeding,whereas EGD grading was not a predictor of subsequent *** HFIUS measurement is more predictive of GOV1 rebleeding than EGD grading,so HFIUS measurement may be necessary for endoscopic follow-up after EVL in patients with GOV1.

关键词： Endoscopic variceal ligation Esophagogastroduodenoscopy High-frequency intraluminal ultrasound Rebleeding Type 1 gastric varices

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Electrochemically Deposited CZTSSe Thin Films for Monolithic Perovskite Tandem solar Cells with Efficiencies Over 17%

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Energy & Environmental Materials 2024年第1期7卷 147-152页

作者： Sun Kyung Hwang Ik Jae Park Se Won Seo Jae Hyun Park so Jeong Park Jin young Kim Department of Materials Science and Engineering Seoul National UniversitySeoul 08826Korea Department of Applied Physics Sookmyung Women's UniversitySeoul 04310Korea Research Institute of Advanced Materials and Systems Sookmyung Women's UniversitySeoul 04310Korea Research Institute of Advanced Materials(RIAM) Seoul National UniversitySeoul 08826Korea

In spite of the high potential economic feasibility of the tandem solar cells consisting of the halide perovskite and the kesterite Cu2ZnSn(S,Se)4(CZTSSe),they have rarely been demonstrated due to the difficulty in implementing solution-processed perovskite top cell on the rough surface of the bottom ***,we firstly demonstrate an efficient monolithic two-terminal perovskite/CZTSSe tandem solar cell by significantly reducing the surface roughness of the electrochemically deposited CZTSSe bottom *** surface roughness(R_(rms))of the CZTSSe thin film could be reduced from 424 to 86 nm by using the potentiostatic mode rather than using the conventional galvanostatic mode,which can be further reduced to 22 nm after the subsequent ion-milling *** perovskite top cell with a bandgap of 1.65 eV could be prepared using a solution process on the flattened CZTSSe bottom cell,resulting in the efficient perovskite/CZTSSe tandem solar *** the current matching between two subcells involving the thickness control of the perovskite layer,the best performing tandem device exhibited a high conversion efficiency of 17.5%without the hysteresis effect.

关键词： CZTSSe monolithic tandem solar cells perovskite solution process surface roughness control

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Short-term interval combined chemoembolization and radiofrequency ablation for hepatocellular carcinoma

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World Journal of Gastroenterology 2014年第35期20卷 12588-12594页

作者： Won Hyeok Choe young Jun Kim Hee Sun Park Sang Woo Park Jeong Han Kim so young Kwon Department of Internal Medicine Konkuk University School of Medicine Department of Radiology Konkuk University School of Medicine

AIM: To investigate hepatic function after combined transcatheter arterial chemoembolization (TACE) and radiofrequency ablation (RFA) with a short-term interval (0-2 d).

关键词： Child-Pugh score Liver cirrhosis Hepatocellular carcinoma Transcatheter arterial chemoembolization Radiofrequency ablation

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On the Relations of Graph Parameters and Its Total Parameters

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Acta Mathematicae Applicatae Sinica 2010年第3期26卷 525-528页

作者： Jing-wen Li Zhi-wen Wang Jaeun Lee Moo young sohn Zhong-fu Zhang En-qiang Zhu Institute of Applied Mathematics Lanzhou Jiaotong University Lanzhou 730070 China School of Mathematics and Computer Science Ningxia University Yinchuan 750021 China Department of Mathematics Yeungnam University Kyongsan 712-749 Korea Department of Applied Mathematics Changwon University Changwon 641 773 Korea

In this paper we get some relations between α（G）, α＇（G）, β（G）, β＇（G） and αT（G）, βT（G）. And all bounds in these relations are best possible, where α（G）, α＇（G）,/3（G）, β（G）, αT（G） and βT（G） are the covering number, edge-covering number, independent number, edge-independent number （or matching number）, total covering number and total independent number, respectively.

关键词： Graph covering number edge covering number independent number edge independent number,total covering number total independent number

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Sex disparity in viral load, inflammation and liver damage in transgenic mice carrying full hepatitis B virus genome with the W4P mutation in the preS1 region

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World Journal of Gastroenterology 2018年第10期24卷 1084-1092页

作者： Seoung-Ae Lee so-young Lee Yu-Min Choi Hong Kim Bum-Joon Kim Department of Microbiology and Immunology Biomedical Sciences Liver Research Institute and Cancer Research Institute Seoul National University College of Medicine

AIM To study sex disparity in susceptibility to hepatocellular carcinoma(HCC), we created a transgenic mouse model that expressed the full hepatitis B virus(HBV) genome with the W4P *** Transgenic mice were generated by transferring the p HY92-1.1 x-HBV-full genome plasmid(genotype A2) into C57 Bl/6 N mice. We compared serum levels of hepatitis B surface antigen(HBs Ag), interleukin(IL)-6, and the liver enzymes alanine aminotransferase(ALT) and aspartate transaminase(AST), as well as liver histopathological features in male and female transgenic(W4PTG) mice and in nontransgenic littermates of 10 mo of age. RESULTS W4PTG males exhibited more pronounced hepatomegaly, significantly increased granule generation in liver tissue, elevated HBs Ag expression in the liver and serum, and higher serum ALT and IL-6 levels compared to W4PTG females or littermate control groups. CONCLUSION Together, our data indicate that the W4 P mutation in pre S1 may contribute to sex disparity in susceptibility to HCC by causing increased HBV virion replication and enhanced IL-6-mediated inflammation in male individuals. Additionally, our transgenic mouse model that expresses full HBV genome with the W4 P mutation in pre S1 could be effectively used for the studies of the progression of liver diseases, including HCC.

关键词： Hepatitis B virus W4P mutation of preS1 transgenic mice Hepatocellular carcinoma

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Non-Invasive Measurements of Thickness of Superconductor Films by Using Two-Resonant-Mode Rutile Resonator

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Chinese Physics Letters 2010年第8期27卷 203-206页

作者： JUNG Ho Sang YANG Woo Il LEE Jae Hun sohn Jae Min CHOO Kee Nam KIM Bong Goo LEE Sang young Department of Physics and Center for Wireless Transmission Technology Konkuk University Seoul 143-701 Korea Research Reactor Engineering Division Korea Atomic Energy Research Institute Daejeon 305-600 Korea

The film thickness should be known for extrazting the intrinsic surface resistance from the effective surface resistance as measured by using the dielectric resonator method. Thicknesses of 70 nm to 360 nm are measured for YBa2 Cu3 O7-δ films in a non-invasive way by using the two-resonant-mode dielectric resonator （TDR） method. A futile resonator with the respective resonant frequencies of 15.25-15.61 GHz and 15.10-15.37 GHz for the TE021 and the TE012 modes is used for this purpose. Differences between the values as measured by using the TDR technique and those measured by using a step profilometer appear to be less than 3%, which is smaller than the previous value of 5% as measured by using a 8. 6 GHz single-resonance mode futile resonator [Lee et al. J. Korean Phys. soc. 54（2009）1619]. Merits of using the TDR method are discussed.

关键词： THICKNESS measurement SUPERCONDUCTORS THIN films RUTILE DIELECTRIC resonators PROFILOMETER ELECTRIC resistance SURFACES (Technology)

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Glucocorticoid pulse therapy in an elderly patient with post-COVID-19 organizing pneumonia:A case report

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World Journal of Clinical Cases 2023年第17期11卷 4152-4158页

作者： Shinhee Park youngeun Jang so-My Koo Bo Da Nam Hee-young Yoon Division of Allergy and Pulmonary Medicine Department of Internal MedicineSoonchunhyang University Bucheon HospitalBucheon 14584South Korea Division of Allergy and Respiratory Diseases Department of Internal MedicineSoonchunhyang University Seoul HospitalSeoul 04401South Korea Department of Radiology Soonchunhyang University Seoul HospitalSeoul 04401South Korea

BACKGROUND Pulmonary fibrosis often occurs as a sequel of coronavirus disease 2019(COVID-19);however,in some cases,it can rapidly progress,similar to the acute exacerbation of interstitial lung *** are the standard treatment for severe COVID-19 pneumonia requiring oxygen supply;however,the post-COVID-19 efficacy of high-dose steroid therapy remains ***,we presented a case of an 81-year-old man who developed acute respiratory failure after COVID-19 and was treated with glucocorticoid pulse *** SUMMARY An 81-year-old man with no respiratory symptoms was admitted due to a diabetic *** had been previously treated for COVID-19 pneumonia six weeks ***,upon admission,he suddenly complained of dyspnea and required a high-flow oxygen *** simple chest radiography and computed tomography(CT)revealed diffuse ground-glass opacities and consolidation in both ***,repeated sputum tests did not identify any infectious pathogens,and initial broad-spectrum antibiotic therapy did not result in any clinical improvement with the patient having an increasing oxygen *** patient was diagnosed with post-COVID-19 organizing ***,we initiated glucocorticoid pulse therapy of 500 mg for three days followed by a tapered dose on hospital day(HD)*** three days of pulse treatment,the patient's oxygen demand *** patient was subsequently discharged on HD 41,and chest radiography and CT scans have almost normalized nine months after *** Glucocorticoid pulse therapy may be considered when the usual glucocorticoid dose is ineffective for patients with COVID-19 sequelae.

关键词： Coronavirus Glucocorticoid Lung disease Interstitial Organizing pneumonia Case report

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Regulatory elements and transcriptional control of chicken vasa homologue(CVH)promoter in chicken primordial germ cells

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Journal of Animal Science and Biotechnology 2017年第2期8卷 490-500页

作者： so Dam Jin Bo Ram Lee young Sun Hwang Hong Jo Lee Jong Seop Rim Jae Yong Han Department of Agricultural Biotechnology Research Institute of Agriculture and Life Sciences College of Agriculture and Life Sciences Seoul National University Institute for Biomedical Sciences Shinshu University

Background： Primordial germ cells（PGCs）, the precursors of functional gametes, have distinct characteristics and exhibit several unique molecular mechanisms to maintain pluripotency and germness in comparison to somatic cells. They express germ cel-specific RNA binding proteins（RBPs） by modulating tissue-specific cis-and trans-regulatory elements. Studies on gene structures of chicken vasa homologue（CVH）, a chicken RNA binding protein, involved in temporal and spatial regulation are thus important not only for understanding the molecular mechanisms that regulate germ cel fate, but also for practical applications of primordial germ cells. However, very limited studies are available on regulatory elements that control germ cel-specific expression in chicken. Therefore, we investigated the intricate regulatory mechanism（s） that governs transcriptional control of ***： We constructed green fluorescence protein（GFP） or luciferase reporter vectors containing the various 5′ flanking regions of CVH gene. From the 5′ deletion and fragmented assays in chicken PGCs, we have identified a CVH promoter that locates at-316 to ＋275 base pair fragment with the highest luciferase activity. Additional y, we confirmed for the first time that the 5′ untranslated region（UTR） containing intron 1 is required for promoter activity of the CVH gene in chicken PGCs. Furthermore, using a transcription factor binding prediction, transcriptome analysis and siR NA-mediated knockdown,we have identified that a set of transcription factors play a role in the PGC-specific CVH gene ***： These results demonstrate that cis-elements and transcription factors localizing in the 5′ flanking region including the 5′ UTR and an intron are important for transcriptional regulation of the CVH gene in chicken PGCs. Final y,this information wil contribute to research studies in areas of reproductive biology, constructing of germ cel-specific synthetic promoter for tracing primordial germ ce

关键词： Chicken Chicken vasa homologue Primordial germ cel Regulatory element siRNA-mediated knockdown

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