Disseminated soft tissue diffuse large B-cell lymphoma involving multiple abdominal wall muscles:A case report
作者机构:Department of Internal MedicineJeonbuk National University Medical SchoolJeonju 54907South Korea
出 版 物:《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期:2021年第9卷第28期
页 面:8557-8562页
核心收录:
学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题:Primary extranodal diffuse large B-cell lymphoma Soft tissue lymphoma Disseminated muscles and soft tissue invasion Atypical presentation of diffuse large B�cell lymphoma Central nervous system relapse Case report
摘 要:BACKGROUND Diffuse large B-cell lymphoma(DLBCL)is the most common subtype of non�Hodgkin lymphoma,and patients with DLBCL typically present rapidly growing *** involving muscle is rare and accounts for only 5%;furthermore,multiple muscles and soft tissue involvement of DLBCL is *** to unusual clinical manifestation,accurate diagnosis could be *** SUMMARY A 61-year-old man complained of swelling,pain and erythematous changes in the lower ***,soft tissue infection was suspected,however,skin lesion did not respond to antibiotics.18Fluoro-2-deoxy-D-glucose(18F-FDG)positron emission tomography-computed tomography demonstrated FDG uptake not only in the skin and subcutaneous tissue of the abdomen but also in the abdominal wall muscles,peritoneum,perineum,penis and *** was confirmed by biopsy of the abdominal wall muscle and subcutaneous *** intensive treatment including chemotherapy with rituximab,cyclophosphamide,doxorubicin,vincristine and prednisolone,central nervous system prophylaxis(intrathecal injection of methotrexate,cytarabine and hydrocortisone)and orchiectomy,he underwent peripheral blood stem cell mobilization for an autologous hematopoietic stem cell *** intensive treatment,the disease progressed rapidly and the patient showed poor outcome(overall survival,9 mo;disease free survival,3 mo).CONCLUSION The first clinical manifestation of soft tissue DLBCL involving multiple muscles was similar to the infection of the soft tissue.