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婚姻生活七部曲期望与现实 1版

在人衰竭肥厚心肌中肌酸激酶三磷酸腺苷的动力学变化

1989年

作者：（美）史密斯（smith c.s.）沈师光沈　桓译

来源：汇雅图书（南通市图书馆... 评论

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世界核心医学期刊文摘（心脏病学分册） 2007年第2期3卷 32-33页

作者： smith c.s. Bottomley P.A. schulman s.P. R.G. Weiss 刘文秀 carnegie 584 Johns Hopkins Hospital 600 N Wolfe St Baltimore MD 21287-6568 United States.Dr.

背景:由压力过负荷左室肥厚(LVH)向慢性心力衰竭(cHF)的进展可能与能量供应和(或)转运的相对不足相关。方法和结果:作者检测心肌肌酸激酶(cK)代谢产物浓度以及通过cK的三磷酸腺苷(ATP)合成(心脏的主要能量储备),以验证LVH伴cHF患者通过c... 详细信息

背景:由压力过负荷左室肥厚(LVH)向慢性心力衰竭(cHF)的进展可能与能量供应和(或)转运的相对不足相关。方法和结果:作者检测心肌肌酸激酶(cK)代谢产物浓度以及通过cK的三磷酸腺苷(ATP)合成(心脏的主要能量储备),以验证LVH伴cHF患者通过cK的ATP通量受损的假说。

关键词：慢性心力衰竭左室肥厚肥厚心肌能量储备产物浓度收缩性心力衰竭左室质量磷酸肌酸过负荷能

伴低分化灶的管状囊状肾细胞癌:是延胡索酸水合酶缺陷型肾细胞癌的常见形态学模式

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临床与实验病理学杂志 2017年第3期33卷 306-306页

作者： smith s c Trpkov K chen Y B 魏建国(译) 刘勇(校) 不详浙江省绍兴市人民医院病理科绍兴312000 江西省人民医院病理科南昌330006

新近出现的一组高级别肾细胞癌，特别是遗传性平滑肌瘤病和肾细胞癌综合征相关性肾细胞癌，显示延胡索酸水合酶（FH）基因突变和功能缺失。基于这些肿瘤与浸润性腺癌中伴低分化灶的管状囊状癌（Tc—PD）之间具有相似的细胞形态学和临床... 详细信息

新近出现的一组高级别肾细胞癌，特别是遗传性平滑肌瘤病和肾细胞癌综合征相关性肾细胞癌，显示延胡索酸水合酶（FH）基因突变和功能缺失。基于这些肿瘤与浸润性腺癌中伴低分化灶的管状囊状癌（Tc—PD）之间具有相似的细胞形态学和临床病理特征，作者推测这些肿瘤实体之间具有某种关联。

关键词：囊状肾细胞癌延胡索酸水合酶细胞形态学低分化管状缺陷型临床病理特征肿瘤实体

冠心病和其他动脉粥样硬化性血管疾病二级预防指南：2006年版（摘要）

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岭南心血管病杂志 2008年第2期14卷 126-126,129页

作者： smith s c ALLEN J BLAIR s N BONOW R O BRAss L M FONAROW G c GRUNDY s M HIRATZKA L JONEs D KRUMHOLZ H M MOscA L PAsTERNAK R c PEARsON T PFEFFER M A TAUBERT K A

美国心脏学会（American college of cardiology，Acc）与美国心脏病协会（American Heart ***）关于二级预防的共识声明自2001年更新以来，许多临床试验提供了重要证据．进一步支持和拓展了对冠心病和其他动脉粥样硬化性血管疾病（包... 详细信息

美国心脏学会（American college of cardiology，Acc）与美国心脏病协会（American Heart ***）关于二级预防的共识声明自2001年更新以来，许多临床试验提供了重要证据．进一步支持和拓展了对冠心病和其他动脉粥样硬化性血管疾病（包括外周动脉疾病、动脉粥样硬化性主动脉疾病和颈动脉疾病）进行积极控制危险因素治疗的重要性。证据不断涌现，证实对这些患者进行积极而全面的危险因素干预治疗能够改善生存率，减少事件复发以及对介入治疗的需要．并提高生活质量。

关键词：动脉粥样硬化性血管疾病二级预防冠心病危险因素治疗美国心脏病协会摘要指南美国心脏学会

单序列重复子评价的优良高粱自交系间的遗传多样性

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国外作物育种 2001年第3期20卷 105-105页

作者： smith,J·s·c

A comprehensive investigation on nonlinear vibration and bending characteristics of bio-inspired helicoidal laminated composite structures

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 81-100页

作者： s.sAURABH R.KIRAN D.sINGH R.VAIsH V.s.cHAUHAN school of Mechanical and Materials Engineering Indian Institute of Technology Mandi

Bio-inspired helicoidal composite laminates, inspired by the intricate helical structures found in nature, present a promising frontier for enhancing the mechanical properties of structural designs. Hence, this study provides a comprehensive investigation into the nonlinear free vibration and nonlinear bending behavior of bio-inspired composite plates. The inverse hyperbolic shear deformation theory(IHsDT) of plates is employed to characterize the displacement field, with the incorporation of Green-Lagrange nonlinearity. The problem is modeled using the c0finite element method(FEM), and an in-house code is developed in the MATLAB environment to solve it numerically. Various helicoidal layup configurations including helicoidal recursive(HR), helicoidal exponential(HE), helicoidal semi-circular(Hs), linear helicoidal(LH), and Fibonacci helicoidal(FH)with different layup sequences and quasi-isotropic configurations are studied. The model is validated, and parametric studies are conducted. These studies investigate the effects of layup configurations, side-to-thickness ratio, modulus ratios, boundary conditions, and loading conditions at different load amplitudes on the nonlinear vibration and nonlinear bending behaviors of bio-inspired composite plates. The results show that the laminate sequence exerts a substantial impact on both nonlinear natural frequencies and nonlinear bending behaviors. Moreover, this influence varies across different side-to-thickness ratios and boundary conditions of the bio-inspired composite plate.

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Functional and immunological peculiarities of peripheral nerve allografts

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Neural Regeneration Research 2022年第4期17卷 721-727页

作者： Kelly c.s.Roballo Jason P.Gigley Tyler A.smith George D.Bittner Jared s.Bushman school of Pharmacy University of WyomingLaramieWYUSA Department of Molecular Biology University of WyomingLaramieWYUSA Department of Molecular Biosciences University of Texas at AustinAustinTXUSA Department of Neuroscience University of Texas at AustinAustinTXUSA

This review addresses the accumulating evidence that live(not decellularized)allogeneic peripheral nerves are functionally and immunologically peculiar in comparison with many other transplanted allogeneic *** is relevant because live peripheral nerve allografts are very effective at promoting recovery after segmental peripheral nerve injury via axonal regeneration and axon *** the immunological peculiarities of peripheral nerve allografts may also be of interest to the field of transplantation in *** topics are addressed:The first discusses peripheral nerve injury and the potential utility of peripheral nerve allografts for bridging segmental peripheral nerve defects via axon fusion and axon *** second reviews evidence that peripheral nerve allografts elicit a more gradual and less severe host immune response allowing for prolonged survival and function of allogeneic peripheral nerve cells and ***,potential mechanisms that may account for the immunological differences of peripheral nerve allografts are discussed.

关键词： allograft animal model immunology neuroimmunology peripheral nerve injury regeneration repair tissue regeneration tissue transplantation transplant

Damage mechanism identification in composites via machine learning and acoustic emission

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npj computational Materials 2021年第1期7卷 852-866页

作者： c.Muir B.swaminathan A.s.Almansour K.sevener c.smith M.Presby J.D.Kiser T.M.Pollock s.Daly Materials Department University of California-Santa BarbaraSanta BarbaraCAUSA NAsA Glenn Research center ClevelandOHUSA Materials scienceand Engineering Department University of Michigan-Ann ArborAnn ArborMIUSA Mechanical Engineering Department University of California-Santa BarbaraSanta BarbaraCAUSA

Damage mechanism identification has scientific and practical ramifications for the structural health monitoring,design,and application of composite *** advances in machine learning uncover pathways to identify the waveform-damage mechanism relationship in higher-dimensional spaces for a comprehensive understanding of damage *** review evaluates the state of the field,beginning with a physics-based understanding of acoustic emission waveform feature extraction,followed by a detailed overview of waveform clustering,labeling,and error analysis *** requirements for damage mechanism identification in any machine learning framework,including those currently in use,under development,and yet to be explored,are discussed.

关键词： composites composite mechanism

Brain-derived neurotrophic factor signaling in the neuromuscular junction during developmental axonal competition and synapse elimination

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Neural Regeneration Research 2025年第2期20卷 394-401页

作者： Josep Tomàs Víctor cilleros-Mañé Laia Just-Borràs Marta Balanyà-segura Aleksandra Polishchuk Laura Nadal Marta Tomàs carolina silvera-simón Manel M.santafé Maria A.Lanuza Unitat d’Histologia i Neurobiologia(UHNeurob) Facultat de Medicina i Ciències de la SalutUniversitat Rovira i VirgiliReusSpain

During the development of the nervous system,there is an overproduction of neurons and *** competition between neighboring nerve endings and synapses performing different activity levels leads to their elimination or *** have extensively studied the involvement of the brain-derived neurotrophic factor-Tropomyosin-related kinase B receptor neurotrophic retrograde pathway,at the neuromuscular junction,in the axonal development and synapse elimination process versus the synapse *** purpose of this review is to describe the neurotrophic influence on developmental synapse elimination,in relation to other molecular pathways that we and others have found to regulate this *** particular,we summarize our published results based on transmitter release analysis and axonal counts to show the different involvement of the presynaptic acetylcholine muscarinic autoreceptors,coupled to downstream serine-threonine protein kinases A and c(PKA and PKc)and voltage-gated calcium channels,at different nerve endings in developmental *** dynamic changes that occur simultaneously in several nerve terminals and synapses converge across a postsynaptic site,influence each other,and require careful studies to individualize the mechanisms of specific *** describe an activity-dependent balance(related to the extent of transmitter release)between the presynaptic muscarinic subtypes and the neurotrophin-mediated TrkB/p75NTR pathways that can influence the timing and fate of the competitive interactions between the different axon *** downstream displacement of the PKA/PKc activity ratio to lower values,both in competing nerve terminals and at postsynaptic sites,plays a relevant role in controlling the elimination of supernumerary ***,calcium entry through L-and P/Q-subtypes of voltage-gated calcium channels(both channels are present,together with the N-type channel in developing nerve terminals)contributes to red

关键词： acetylcholine release adenosine receptors axonal competition brain-derived neurotrophic factor calcium channels motor end-plate muscarinic acetylcholine receptors postnatal synapse elimination serine kinases tropomyosin-related kinase receptorB