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Adulticidal, larvicidal, pupicidal and oviposition deterrent activities of essential oil from Zanthoxylum limonella Alston(Rutaceae) against Aedes aegypti(L.) and Culex quinquefasciatus(Say)

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Asian Pacific Journal of Tropical Biomedicine 2017年第11期7卷 967-978页

作者： Mayura Soonwera siriporn Phasomkusolsil Department of Plant Production Technology Faculty of Agricultural TechnologyKing Mongkut's Institute of Technology LadkrabangBangkok 10520Thailand Department of Entomology Armed Forces Research Institute of Medical SciencesBangkok 10400Thailand

Objective: To evaluate adulticidal, larvicidal and oviposition deterrent response of the essential oil from dried Zanthoxylum limonella(Z. limonella) fruit against Aedes aegypti(Ae. aegypti) and Culex quinquefasciatus(Cx. quinquefasciatus).Methods: Z. limonella oil was tested by biological assays at 1%, 5% and 10% concentrations in ethanol. Adulticidal efficacy was tested against the 2–3 day old adult females. Larvicidal activity was tested against immature stage of mosquitoes. Oviposition deterrence of the oil was evaluated on gravid ***: The adult mortality was observed after 24 h with the LC50 of 6.0% for ***, and 5.7% for Cx. quinquefasciatus. Larvicidal bioassay was carried out with the 10% Z. limonella oil against immature stages of Ae. aegypti and Cx. quinquefasciatus,which caused 100% mortality after 12 h and 24 h. In the larvicidal experiment,Z. limonella showed effective result at 1%, 5% and 10% concentrations with the values of LT50 Ae. aegypti = 9.78, 5.61, 0.24 h for larvae and LT50= 64.08, 21.23 h for pupae;Cx. quinquefasciatus had LT50= 28.46, 20.25, 1.01 h for larvae and LT50= 67.52, 27.96,4.11 h for pupae, respectively. Oviposition deterrence of the oil was evaluated on gravid females. In the study, 10% Z. limonella showed 100% repellency for Ae. aegypti and99.53% for Cx. quinquefasciatus. Likewise, oviposition activity indexes of these oil concentrations were all negative values ranging from–0.89 to-1.00 for Ae. aegypti and–0.64 to–0.99 for Cx. quinquefasciatus. The oviposition activity indexes values revealed that Z. limonella oil has deterrent effect, and it caused a remarkable negative response resulting in very few ***: This result indicates that Z. limonella oil can be used as an effective adulticide, larvicide and oviposition deterrent against Ae. aegypti and Cx. quinquefasciatus.

关键词： Zanthoxylum limonella Aedes aepypti Culex quinquefasciatus Adulticide Larvicide Oviposition deterrent

Mitochondrial Diversity and Phylogeographic Patterns of Gekko gecko(Squamata: Gekkonidae) in Thailand

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Asian Herpetological Research 2019年第3期10卷 158-169页

作者： Anchalee AOWPHOL siriporn YODTHONG Attapol RUJIRAWAN KumthornTHIRAKHUPT Department of Zoology Faculty of ScienceKasetsart UniversityChatuchakBangkok 10900Thailand Department of Biology Faculty of ScienceChulalongkorn UniversityPathumwanBangkok 10330Thailand

The Tokay Gecko, Gekko gecko(Linnaeus, 1758) is widely distributed in Asia and there have been concerns regarding locally decreasing populations due to overexploitation for traditional Chinese medicine. Previous studies of the genetic relationships of G. gecko populations included few populations from Thailand. Here we investigated the phylogeographic patterns of G. gecko from different regions in Thailand using mitochondrial cytochrome b sequences. Phylogenetic analyses revealed two lineages: one(Lineage A) comprising populations from Laos, Vietnam, and Thailand;and a second(Lineage B) comprising three genetically distinct groups within Thailand alone. Some Thai populations were found to have both lineages represented within them. Highly significant genetic differentiation(FST) showed geographic population structuring in Lineage B, indicating limited gene flow among groups in Thailand. Although G. gecko has a wide distribution and is well adapted to human habitation, the observed genetic structure could potentially be explained by geographic barriers such as mountain ranges. In Lineage A, our study provided primary phylogeographic evidence for lineage mixture that might be a result of human-mediated transport. Future research should include more extensive sampling across the geographic distribution of G. gecko and a landscape genetics approach could be applied for conservation planning.

关键词： genetic structure haplotype Gekkonidae mitochondrial DNA human-mediated transport

Changes in oviduct structure in the black tiger shrimp,Penaeus monodon,during ovarian maturation

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2012年第10期13卷 846-850页

作者： Sitthichai IAMSAARD siriporn SRIURAIRATANA Boonsirm WITHYACHUMNARNKUL Department of Anatomy Faculty of MedicineKhon Kaen UniversityKhon Kaen 40002Thailand Integrative Complementary Alternative Medicine Research and Development Group Faculty of MedicineKhon Kaen UniversityKhon Kaen 40002Thailand Centex Shrimp Faculty of ScienceMahidol UniversityBangkok 10400Thailand Department of Anatomy Faculty of ScienceMahidol UniversityBangkok 10400Thailand

Objective:To examine the structure of the oviduct of the shrimp Penaeus ***:The oviducts of *** with three different major groups of ovarian development(Group(Gr.) 1:Stages I & V;Gr.2:Stages II & III;and Gr.3:Stage IV) were examined by light,transmission electron,and scanning electron microscopies,***:The epithelium of the oviduct in Gr.1 was composed of tall simple columnar cells with their basal nuclei located on the basement membrane and its thick collagen *** Gr.2,the oviduct seemed to produce some substances and their epithelial cells became transitional with centrally located nuclei and formed some ***,the epithelial cells in Gr.3(at Stage IV) were disorganized,disrupted,and shed accumulated spherical secretory substances including some cellular contents into the ***:The structural changes of the *** oviduct were related to ovarian maturation stages(Grs.1-3).Prior to spawning,only the oviduct epithelium at ovary Stage IV produced and secreted a number of spherical secretion substances into the *** substances may act as the oviductal lubricants to facilitate the spawning process.

关键词： Oviduct Ovarian maturation Black tiger shrimp Penaeus monodon Spherical secretory substances

Ionic liquids for high performance lithium metal batteries

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Journal of Energy Chemistry 2021年第8期30卷 320-333,I0007页

作者： Kexin Liu Zhuyi Wang Liyi Shi siriporn Jungsuttiwong Shuai Yuan School of Materials Science and Engineering Shanghai University200444 ShanghaiChina Research Centre of Nanoscience and Nanotechnology Shanghai University200444 ShanghaiChina Center for Organic Electronic and Alternative Energy Department of Chemistry and Center of Excellence for Innovation in ChemistryFaculty of ScienceUbon Ratchathani University34190 Ubon RatchathaniThailand Emerging Industries Institute Shanghai UniversityJiaxing 314006China

The pursuit of high energy density has promoted the development of high-performance lithium metal ***,it faces a serious security *** liquids have attracted great attention due to their high ionic conductivity,non-flammability,and the properties of promoting the formation of stable SEI *** understanding the problems existing in lithium metal batteries and the role of ionic liquids in them is of great significance for improving the performance of lithium metal *** article reviews the effects of the molecular structure of ionic liquids on ionic conductivity,Li^(+)ion transference number,electrochemical stability window,and lithium metal anode/electrolyte interface,as well as the application of ionic liquids in Li-high voltage cathode batteries,Li-O_(2) batteries and Li-S *** molecular design,composition and polymerization will be the main strategies for the future development of ionic liquid-based electrolytes for high performance lithium metal battery.

关键词： Ionic liquids Li+ion conduction Interface issues Lithium metal battery

Current opinion on the regulation of small intestinal magnesium absorption

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World Journal of Gastroenterology 2023年第2期29卷 332-342页

作者： siriporn Chamniansawat Nasisorn Suksridechacin Narongrit Thongon Division of Anatomy Department of Medical SciencesFaculty of Allied Health SciencesBurapha UniversityMuang 20131ChonburiThailand Biodiversity Research Centre Thailand Institute of Scientific and Technological ResearchKhlong Luang 12120Pathum ThaniThailand Division of Physiology Department of Medical SciencesFaculty of Allied Health SciencesBurapha UniversityMuang 20131ChonburiThailand

Magnesium(Mg^(2+))has an important role in numerous biological functions,and Mg^(2+)deficiency is associated with several ***,adequate intestinal absorption of Mg^(2+)is vital for *** small intestine was previously thought to absorb digested Mg^(2+)exclusively through an unregulated paracellular mechanism,which is responsible for approximately 90%of total Mg^(2+)*** studies,however,have revealed that the duodenum,jejunum,and ileum absorb Mg^(2+)through both transcellular and paracellular *** regulatory factors of small intestinal Mg^(2+)uptake also have been explored,e.g.,parathyroid hormone,fibroblast growth factor-23,apical acidity,proton pump inhibitor,and pH-sensing channel and *** mechanistic factors underlying proton pump inhibitor suppression of small intestinal Mg^(2+),such as magnesiotropic protein dysfunction,higher mucosal bicarbonate secretion,Paneth cell dysfunction,and intestinal inflammation,are currently being *** potential role of small intestinal microbiomes in Mg^(2+)absorption has also been *** this article,we reviewed the current knowledge on the mechanisms and regulatory factors of small intestinal Mg^(2+)absorption.

关键词： Hormone Magnesium absorption Paneth cells Proton pump inhibitor Regulation Small intestine

A cation-dipole-reinforced elastic polymer electrolyte enabling long-cycling quasi-solid-state lithium metal batteries

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Journal of Energy Chemistry 2022年第12期75卷 340-348,I0009页

作者： Zhuyi Wang Yiming Wang Pan Zhai Preeyaporn Poldorn siriporn Jungsuttiwong Shuai Yuan Research Centre of Nanoscience and Nanotechnology Shanghai UniversityShanghai 200444China Center for Organic Electronic and Alternative Energy Department of Chemistry and Center of Excellence for Innovation in ChemistryFaculty of ScienceUbon Ratchathani UniversityUbon Ratchathani 34190Thailand

The application of ionic liquids(IL)in polymer electrolytes represents a safer alternative to the currently used organic solvents in lithium batteries due to their nonflammability and thermal ***,as a plasticizer,it is generally agreed that the introduction of ionic liquid usually leads to a trade-off between ion transport and mechanical properties of polymer *** we report the synthesis of an IL-embedded polymer electrolyte with both high ionic conductivity(2.77×10^(-4)S cm^(-1)at room temperature)and excellent mechanical properties(high tensile strength up to 11.4 MPa and excellent stretchability of 387%elongation at break)achieved by strong ion–dipole interactions between polymer electrolyte components,which was unveiled by the DFT ***,this polymer electrolyte also exhibits nonflammability,good thermal stability and the ability to recover reversibly from applied stress,i.e.,excellent *** highly viscoelastic polymer electrolyte enables tight interfacial contact and good adaptability with electrodes for stable lithium stripping/plating for 2000 h under a current density of 0.1 mA cm^(-2).By coupling with this polymer electrolyte,the LiFePO_(4)/Li cells exhibit outstanding cycling stability at room temperature as well as the reliability under extreme environmental temperature or being abused.

关键词： Elastic polymer electrolyte Ion-dipole interactions High tensile strength Quasi-solid-state lithium battery Long cycling

Effect of prolonged omeprazole administration on segmental intestinal Mg2+ absorption in male Sprague-Dawley rats

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World Journal of Gastroenterology 2020年第11期26卷 1142-1155页

作者： Nasisorn Suksridechacin Punnisa Kulwong siriporn Chamniansawat Narongrit Thongon Division of Physiology Department of Biomedical SciencesFaculty of Allied Health SciencesBurapha UniversityChonburi 20131Thailand Division of Anatomy Department of Biomedical SciencesFaculty of Allied Health SciencesBurapha UniversityChonburi 20131Thailand

BACKGROUND The exact mechanism of proton pump inhibitors(PPIs)-induced hypomagnesemia(PPIH) is largely unknown. Previous studies proposed that PPIH is a consequence of intestinal Mg2+ malabsorption. However, the mechanism of PPIs-suppressed intestinal Mg2+ absorption is under *** To investigate the effect of 12-wk and 24-wk omeprazole injection on the total,transcellular, and paracellular Mg2+ absorption in the duodenum, jejunum, ileum,and colon of male Sprague-Dawley *** The rats received 20 mg/kg·d subcutaneous omeprazole injection for 12 or 24 *** and urinary Mg2+, Ca2+, and PO43-levels were measured. The plasma concentrations of 1α,25-dihydroxyvitamin D3(1α,25(OH)2D3), parathyroid hormone(PTH), fibroblast growth factor 23(FGF-23), epidermal growth factor(EGF), and insulin were also observed. The duodenum, jejunum, ileum, and colon of each rat were mounted onto individual modified Using chamber setups to study the rates of total, transcellular, and paracellular Mg2+ absorption simultaneously. The expression of transient receptor potential melastatin 6(TRPM6) and cyclin M4(CNNM4) in the entire intestinal tract was also *** Single-dose omeprazole injection significantly increased the intraluminal p H of the stomach, duodenum, and jejunum. Omeprazole injection for 12 and 24 wk induced hypomagnesemia with reduced urinary Mg2+ excretion. The plasma Ca2+ was normal but the urinary Ca2+ excretion was reduced in rats with PPIH. The plasma and urinary PO43-levels increased in PPIH rats. The levels of1α,25(OH)2D3 and FGF-23 increased, whereas that of plasma EGF decreased in the omeprazole-treated rats. The rates of the total, transcellular, and paracellular Mg2+ absorption was significantly lower in the duodenum, jejunum, ileum, and colon of the rats with PPIH than in those of the control rats. The percent suppression of Mg2+ absorption in the duodenum, jejunum, ileum, and colon of the rats with PPIH compared with the control rats was 81.

关键词： Adverse effect Colon Mg2+absorption Proton pump inhibitors-induced hypomagnesemia Small intestine

Dose requirement and complications of diluted and undiluted propofol for deep sedation in endoscopic retrograde cholangiopancreatography

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Hepatobiliary & Pancreatic Diseases International 2011年第3期10卷 313-318页

作者： Somchai Amornyotin Wichit Srikureja Wiyada Chalayonnavin siriporn Kongphlay Department of Anesthesiology and Siriraj GI Endoscopy Center Faculty of MedicineSiriraj HospitalMahidol University Section of Gastroenterology Loma Linda University Medical Center

BACKGROUND:In general,the dose requirement and complications of propofol are lower when used in the diluted form than in the undiluted *** aim of this study was to determine the dose requirement and complications of diluted and undiluted propofol for deep sedation in endoscopic retrograde ***:Eighty-six patients were randomly assigned to either group D (diluted propofol) or U (undiluted propofol).All patients were sedated with 0.02-0.03 mg/kg midazolam (total dose ≤2 mg for age <70 years and 1 mg for age ≥70) and 0.5-1 μg/kg fentanyl (total dose ≤75 μg for age <70 and ≤50 μg for age ≥70).Patients in group U (42) were sedated with standard undiluted propofol (10 mg/mL).Patients in group D (44) were sedated with diluted propofol (5 mg/mL).All patients in both groups were monitored for the depth of sedation using the Narcotrend *** primary outcome variable was the total dose of propofol used during the *** secondary outcome variables were complications during and immediately after the procedure,and recovery ***:All endoscopies were completed *** propofol doses per body weight and per body weight per hour in groups D and U were 3.0 mg/kg,6.2 mg/kg per hour and 4.7 mg/kg,8.0 mg/kg per hour,*** mean dose of propofol,expressed as total dose,dose/kg or dose/kg per hour and the recovery time were not significantly different between the two ***-related adverse events during and immediately after the procedure were higher in group U (42.9%) than in group D (18.2%) (P=0.013).CONCLUSIONS:Propofol requirement and recovery time in the diluted and undiluted propofol groups were ***,the sedation-related hypotension was significantly lower in the diluted group than the undiluted group.

关键词： propofol dose requirement complication endoscopic retrograde cholangiopancreatography

Phosphodiesterase-3 inhibitor （cilostazol） attenuates oxidative stress-induced mitochondrial dysfunction in the heart

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Journal of Geriatric Cardiology 2014年第2期11卷 151-157页

作者： siriporn C. Chattipakom Savitree Thummasorn Jantira Sanit Nipon Chattipakorn Cardiac Electrophysiology Research and Training Center Department of Physiology Faculty of Medicine Chiang Mai University Chiang Mai 50200 Thailand Faculty of Dentistry Chiang Mai University Chiang Mai 50200 Thailand Biomedical Engineering Center Chiang Mai University Chiang Mai 50200 Thailand

Background Cilostazol is a type 3 phosphodiesterase inhibitor which has been previously demonstrated to prevent the occurrence of tachyarrhythmia and improve defibrillation efficacy. However, the mechanism for this beneficial effect is still unclear. Since cardiac mito-chondria have been shown to play a crucial role in fatal cardiac arrhythmias and that oxidative stress is one of the main contributors to arr-hythmia generation, we tested the effects of cilostazol on cardiac mitochondria under severe oxidative stress. Methods Mitochondria were isolated from rat hearts and treated with H2O2 to induce oxidative stress. Cilostazol, at various concentrations, was used to study its protective effects. Pharmacological interventions, including a mitochondrial permeability transition pore （mPTP） blocker, cyclosporine A （CsA）, and an inner membrane anion channel （IMAC） blocker, 4＇-chlorodiazepam （CDP）, were used to investigate the mechanistic role of cilostazol on cardiac mitochondria. Cardiac mitochondrial reactive oxygen species （ROS） production, mitochondrial membrane potential change and mi-tochondrial swelling were determined as indicators of cardiac mitochondrial function. Results Cilostazol preserved cardiac mitochondrial function when exposed to oxidative stress by preventing mitochondrial depolarization, mitochondrial swelling, and decreasing ROS produc-tion. Conclusions Our findings suggest that cardioprotective effects of cilostazol reported previously could be due to its prevention of car-diac mitochondrial dysfunction caused by severe oxidative stress.

关键词： Phosphodiesterase-3 inhibitor Cilostazol Mitochondria Heart Oxidative stress Membrane potential Ischemia