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Fecal microbiome of growing pigs fed a cereal based diet including chicory(Cichorium intybus L.) or ribwort(Plantago lanceolata L.) forage

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Journal of Animal Science and Biotechnology 2016年第2期7卷 167-175页

作者： johan Dicksved Janet K.Jansson Jan Erik Lindberg Department of Animal Nutrition and Management Swedish University of Agricultural Sciences Department of Microbiology Swedish University of Agricultural Sciences Division of Biology Earth and Biological Sciences Pacific Northwest National Laboratories

Background： The purpose of this study was to investigate how inclusion of chicory forage or ribwort forage in a cereal-based diet influenced the fecal microbial community（microbiome） in newly weaned（35 days of age） *** piglets were fed a cereal-based diet without（B） and with inclusion（80 and 160 g/kg air-dry forage） of vegetative shoots of chicory（C） and leaves of ribwort（R） forage in a 35-day growth trial. Fecal samples were collected at the start（D0）, 17（D17） and 35（D35） days after weaning and profiles of the microbial consortia were generated using terminal restriction fragment length polymorphism（T-RFLP）. 454-FLX pyrosequencing of 16 S r RNA gene amplicons was used to analyze the microbial composition in a subset of the samples already analyzed with ***： The microbial clustering pattern was primarily dependent on age of the pigs, but diet effects could also be observed. Lactobacilli and enterobacteria were more abundant at D0, whereas the genera Streptococcus, Treponema,Clostridium, Clostridiaceae1 and Coprococcus were present in higher abundances at D35. Pigs fed ribwort had an increased abundance of sequences classified as Treponema and a reduction in lactobacilli. However, the abundance of Prevotellaceae increased with age in on both the chicory and the ribwort diet. Moreover, there were significant correlations between the abundance of Bacteroides and the digested amount of galactose, uronic acids and total non-starch polysaccharides, and between the abundance of Bacteroidales and the digested amount of ***： This study demonstrated that both chicory and ribwort inclusion in the diet of newly weaned pigs influenced the composition of the fecal microbiota and that digestion of specific dietary components was correlated with species composition of the microbiota. Moreover, this study showed that the gut will be exposed to a dramatic shift in the microbial community structure several weeks after weaning.

关键词： Amplicon sequencing Chicory Microbiome Ribwort Uronic acid Weaning 16S

Constant Angle Surfaces in the Heisenberg Group

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Acta Mathematica Sinica,English Series 2011年第4期27卷 747-756页

作者： johan FASTENAKELS Marian Ioan MUNTEANU Joeri VAN DER VEKEN Department of Mathematics Katholieke Universiteit Leuven Celestijnenlaan 200B-Box 2400 BE-3001 Leuven Belgium 'Al. I. Cuza' University of Iasi Bd. Carol I n. 11 700506-Iasi Romania

In this article we extend the notion of constant angle surfaces in S2 × R and H2 ×R to general Bianchi-Cartan-Vranceanu spaces. We show that these surfaces have constant Gaussian curvature and we give a complete loc... 详细信息

关键词： Heisenberg group Bianchi-Cartan Vranceanu space constant angle surface

Serum amyloid P component:a new biomarker for low sperm concentration?

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Asian Journal of Andrology 2021年第5期23卷 450-455页

作者： Annika Sonesson johan Malm Lars Rylander Aleksander Giwercman Andreas Hillarp Department of Translational Medicine Lund UniversityMalmo 20502Sweden University and Regional Laboratories Region Skane Department of Clinical Chemistry and PharmacologyMalmo 20502Sweden Department of Laboratory Medicine Division of Occupational and Environmental MedicineLund UniversityLund 22381Sweden

Serum amyloid P component(SAP)is present in seminal plasma,on spermatozoa,and in different tissues of the male reproductive tract,but its function is not *** aims of this study were to determine if the concentration of SAP in seminal plasma is associated with commonly assessed semen parameters and to investigate if SAP could be a new,indirect biomarker for these *** a cross-sectional study of 203 young volunteers,the concentration of SAP in seminal plasma was measured with a in-house developed enzyme-linked immunosorbent *** plots,Pearson’s correlation coefficients(r),and linear regression models were produced,and SAP showed a statistically significant correlation with sperm concentration(r=0.75),sperm number(r=0.68),semen volume(r=-0.19),progressive sperm motility(r=0.24),and sperm immotility(r=-0.20).When the study group was dichotomized,SAP could be used to discriminate samples with a sperm concentration

关键词： fertility reproduction seminal plasma serum amyloid P component sperm

Management of BPH then 2000 and now 2016-From BPH to BPO

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Asian Journal of Urology 2017年第3期4卷 138-147页

作者： johan Braeckman Louis Denis Department of Urology UZ BrusselBrusselsBelgium Oncology Center Antwerp(OCA) AntwerpBelgium

The diagnosis and treatment of benign prostatic obstruction(BPO)is based on a number of well-known lower urinary tract symptoms(LUTS)feared by all ageing males with functional *** ascent of modern urology turned this disease from lethal into an annoying but treatable health problem in the previous *** are able to relieve the great majority of patients from their bothersome symptoms to a respectable quality of life by medication or removal of the obstructive part of the enlarged *** can be proud of some progress made in the new millennium to reach a correct diagnosis and subsequent choice of treatment aiming for quality of life and cost-efficiency for public *** it remains symptomatic treatment and we expect the new generation of urologists to close some gaps in our knowledge on the regulation of prostatic growth to focus on prevention and elimination of the disease in the foreseeable future.

关键词： Benign prostate hyperplasia Benign prostatic obstruction Lower urinary tract symptoms Pharmacological treatment Transurethral resection of the prostate Laser prostatectomy Minimal invasive treatment

Does Corporate Social Responsibility Really Make a Difference? An Explorative Analysis for Chinese Companies

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China & World Economy 2014年第2期22卷 102-124页

作者： johan Graafland Hugo Smid CentER Tilburg Sustainability CenterEuropean Banking CenterDepartment of Economics/Department of PhilosophyTilburgthe Netherlands CentER Tilburg Sustainability CenterDepartment of EconomicsTilburgthe Netherlands

Many studies have been performed to assess the impacts of corporate social responsibility （CSR） on the financial performance of companies. There are, however, very few studies that analyze how CSR policies and instruments affect the realization of social and environmental CSR goals, such as the reduction of workplace accidents or CO2 emissions. Therefore, it remains uncertain to what extent CSR really contributes to sustainable development and whether it can serve as an alternative to government regulation to internalize external effects from market operation. The present study provides an explorative empirical analysis that aims to fill this gap. We employ regression analysis on a sample of 109 Chinese companies. The estimation results show that having a code of conduct stimtdates the implementation of other organizational CSR instruments, but CSR implementation only partly affects the realization of CSR goals. Having codes of conduct without implementing CSR does not have a significant impact on societal welfare.

关键词： China corporate social responsibility environmental impact management system social impact,

Early-onset gastric cancer:Learning lessons from the young

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World Journal of Gastrointestinal Oncology 2010年第2期2卷 59-64页

作者： Anya N Milne G johan A Offerhaus Department of Pathology University Medical Centre Utrecht Department of Pathology Academic Medical CentreUniversity of Amsterdam

There is by no means a clear-cut pattern of mutations contributing to gastric cancers,and gastric cancer research can be hampered by the diversity of factors that can induce gastric cancer,such as Helicobacter pylori infection,diet,ageing and other environmental *** are unquestionably riddled with genetic changes yet we are faced with an unsolvable puzzle with respect to a temporal *** is postulated that inherited genetic factors may be more important in early-onset gastric cancer (EOGC) than in gastric cancers found in older patients as they have less exposure to environmental ***,therefore,could provide a key to unravelling the genetic changes in gastric *** cancers occurring in young patients provide an ideal background on which to try and uncover the initiating stages of gastric *** review summarizes the literature regarding EOGC and also presents evidence that these cancers have a unique molecular-genetic phenotype,distinct from conventional gastric cancer.

关键词： Gastric cancer Early-onset gastric cancer Helicobacter pylori

Automatic Classification of Swedish Metadata Using Dewey Decimal Classification:A Comparison of Approaches

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Journal of Data and Information Science 2020年第1期5卷 18-38页

作者： Koraljka Golub johan Hagelback Anders Ardo Department of Cultural Sciences Faculty of Arts and HumanitiesLinnaeus UniversityVaxjoSweden Department of Computer Science and Media Technology Faculty of TechnologyLinnaeus UniversityKalmarSweden Department of Electrical and Information Technology Lund UniversityLundSweden

Purpose:With more and more digital collections of various information resources becoming available,also increasing is the challenge of assigning subject index terms and classes from quality knowledge organization *** the ultimate purpose is to understand the value of automatically produced Dewey Decimal Classification(DDC)classes for Swedish digital collections,the paper aims to evaluate the performance of six machine learning algorithms as well as a string-matching algorithm based on characteristics of ***/methodology/approach:State-of-the-art machine learning algorithms require at least 1,000 training examples per *** complete data set at the time of research involved 143,838 records which had to be reduced to top three hierarchical levels of DDC in order to provide sufficient training data(totaling 802 classes in the training and testing sample,out of 14,413 classes at all levels).Findings:Evaluation shows that Support Vector Machine with linear kernel outperforms other machine learning algorithms as well as the string-matching algorithm on average;the string-matching algorithm outperforms machine learning for specific classes when characteristics of DDC are most suitable for the *** embeddings combined with different types of neural networks(simple linear network,standard neural network,1 D convolutional neural network,and recurrent neural network)produced worse results than Support Vector Machine,but reach close results,with the benefit of a smaller representation *** of features in machine learning shows that using keywords or combining titles and keywords gives better results than using only titles as *** only marginally improves the *** stop-words reduced accuracy in most cases,while removing less frequent words increased it *** greatest impact is produced by the number of training examples:81.90%accuracy on the training set is achieved when at least 1,000 records per class are available

关键词： LIBRIS Dewey Decimal Classification Automatic classification Machine learning Support Vector Machine Multinomial Naive Bayes Simple linear network Standard neural network 1D convolutional neural network Recurrent neural network Word embeddings String matching

Gastroenterostoma after Billroth antrectomy as a premalignant condition

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World Journal of Gastroenterology 2012年第25期18卷 3201-3206页

作者： Robert Sitarz Ryszard Maciejewski Wojciech P Polkowski G johan A Offerhaus Department of Pathology University Medical CentreUtrecht3584 CX UtrechtThe Netherlands Department of Human Anatomy Medical University of Lublin20-950 LublinPoland Department of Surgical Oncology Medical University of Lublin20-081 LublinPoland Department of Pathology Academic Medical Centre 1105 AZ Amsterdam The Netherlands

Gastric stump carcinoma （GSC） following remote gastric surgery is widely recognized as a separate entity within the group of various types of gastric cancer. Gastrecto- my is a well established risk factor for the development of GSC at a long time after the initial surgery. Both exo- as well as endogenous factors appear to be involved in the etiopathogenesis of GSC, such as achlorhydria, hypergastrinemia and biliary reflux, Epstein-Barr virus and Helicobacter pylori infection, atrophic gastritis, and also some polymorphisms in interleukin-l~ and maybe cyclo-oxygenase-2. This review summarizes the litera- ture of GSC, with special reference to reliable early di- agnostics. In particular, dysplasia can be considered as a dependable morphological marker. Therefore, close endoscopic surveillance with multiple biopsies of the gastroenterostomy is recommended. Screening start- ing at 15 years after the initial ulcer surgery can detect tumors at a curable stage. This approach can be ofspecial interest in Eastern European countries, where surgery for benign gastroduodenal ulcers has remained a practice for a much longer time than in Western Eu- rope, and therefore GSC is found with higher frequency.

关键词： Gastric stump cancer Gastrectomy Riskfactors Endoscopic surveillance

Wide Speed Range Permanent Magnet Synchronous Generator Design for a DC Power System

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Chinese Journal of Electrical Engineering 2017年第1期3卷 33-41页

作者： Dongmin Miao Yves Mollet johan Gyselinck Jianxin Shen Department of Bio Electro And Mechanical SystemsUniversitéLibre de BruxellesBrussels1050Belgium Department of Electrical Engineering Zhejiang UniversityHangzhou310027China

A wide speed range permanent magnet synchronous generator(PMSG)system is studied in this paper,including the PMSG design and comparative study on control strategies with a pulse width modulation(PWM)rectifier,the purpose of which is to regulate the DC-link *** is of great importance to study the foregoing DC power system based on the PMSG and PWM rectifier,where vector control(VC)can be implemented and the corresponding field-weakening strategy can be realized by injecting a field-weakening current component without any auxiliary *** machine inductance is desired in order to limit the short-circuit current and the loaded voltage *** control strategies including VC,direct torque control(DTC)and direct voltage control(DVC)are studied and compared with both simulations and experiments.

关键词： Wide speed range permanent magnet synchronous generator PWM rectifier vector control field-weakening control direct torque control direct voltage control