检索结果-南通市图书馆

Nano Research 2022年第4期15卷 2913-2918页

作者： Yuting Chen Yang Yang Peng Yuan Pengfei Jiang Yuan Wang Yannan Xu Shuxian Lv Yaxin Ding Zhiwei Dang Zhaomeng Gao Tiancheng Gong Yan Wang Qing Luo Key Laboratory of Microelectronic Devices and Integrated Technology Institute of MicroelectronicsChinese Academy of SciencesBeijing 100029China University of Chinese Academy of Sciences Beijing 100049China Department of Mathematics and Theories Peng Cheng LaboratoryNo.2Xingke 1st StreetNanshanShenzhen 518000China

Flexible memory devices are promising for information storage and data processing applications in portable,wearable,and smart electronics operating under curved conditions.In this work,we realized high-performance flexible ferroelectric capacitors based on Hf_(0.5)Zr_(0.5)O_(2)(HZO)thin film by depositing a buffer layer of Al_(2)O_(3)on polyimide(PI)substrates using atomic layer deposition(ALD).The flexible ferroelectric HZO films exhibit high remnant polarization(Pr)of 21μC/cm^(2).Furthermore,deterioration of polarization,retention,and endurance performance was not observed even at a bending radius of 2 mm after 5,000 bending cycles.This work marks a critical step in the development of high-performance flexible HfO_(2)-based ferroelectric memories for next-generation wearable electronic devices.

关键词： ferroelectric Hf_(0.5)Zr_(0.5)O_(2)(HZO) Al_(2)O_(3)buffer layer flexible

古籍病害描述术语规范与破损定级标准研究——关于《古籍特藏破损定级标准》的增订建议

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

大学图书馆学报 2021年第5期39卷 122-128页

作者：吕淑贤北京大学图书馆北京100871

古籍的病害描述术语规范与定级标准是图书馆开展古籍破损调查必要的参考依据。在大量馆藏古籍破损调查工作实践的基础上,通过对比分析古籍、纸质文物和档案三个行业的相关标准中的病害描述术语,进一步规范古籍中常见病害的名称与定义;... 详细信息

古籍的病害描述术语规范与定级标准是图书馆开展古籍破损调查必要的参考依据。在大量馆藏古籍破损调查工作实践的基础上,通过对比分析古籍、纸质文物和档案三个行业的相关标准中的病害描述术语,进一步规范古籍中常见病害的名称与定义;同时参考《古籍特藏破损定级标准》中已有明确量化指标的相关术语为新增术语制订可用于古籍破损定级的量化指标,使现有定级标准更具有实践参考意义。

关键词：古籍病害描述破损定级标准规范

Freely switching between ferroelectric and resistive switching in Hf0.5Zr0.5O2 films and its application on high accuracy on-chip deep neural networks

在线全文

学校读者我要写书评

暂无评论

Science China(Information Sciences) 2023年第2期66卷 267-276页

作者： Pengfei JIANG Kunran XU Jie YU Yannan XU Peng YUAN Yuan WANG Yuting CHEN Yaxin DING Shuxian Lv Zhiwei DANG Tiancheng GONG Yang YANG Yan WANG Qing LUO Key Laboratory of Microelectronics Devices and Integrated Technology Institute of MicroelectronicsChinese Academy of Sciences University of Chinese Academy of Sciences School of Microelectronics Xidian University Peng Cheng Laboratory

The Hf0.5Zr0.5O2(HZO)-based ferroelectric field-effect transistor(Fe FET) synapse is a promising candidate for at-scale deep neural network(DNN) applications, because of its high symmetry, great accuracy and fast operation speed. However, the degradation of the remanent polarization(Pr) over time caused by the depolarization field has not been effectively resolved, greatly affecting the accuracy of the trained DNN. In this study, we demonstrate a ferroelectric(FE)-resistive switching(RS) switchable synapse using the FE mode for high-speed weight training and the RS mode for stable weight storage to overcome accuracy degradation. The FE-RS hybrid characteristic is accomplished by an HZO-based metal-ferroelectricmetal(MFM) capacitor with asymmetric electrodes, and the best FE endurance, as well as the most reliable RS behavior, is demonstrated by testing several electrodes materials. High memory windows are achieved in both FE and RS modes. Through this design, excellent accuracy is maintained over time, as verified by network simulation.

关键词： Hf 0.5 Zr 0.5 O 2 films ferroelectric resistive switching accuracy on-chip DNN

OGG1 inhibition suppresses African swine fever virus replication

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Virologica Sinica 2023年第1期38卷 96-107页

作者： Jie Fan Xinqian lv Saixia Yang shuxian Geng Jifei Yang Yaru Zhao Zhonghui Zhang Zhijie Liu Guiquan Guan Jianxun Luo Qiaoying Zeng Hong Yin Qingli Niu College of Veterinary Medicine Gansu Agricultural UniversityLanzhou730070China African Swine Fever Regional Laboratory of China(Lanzhou) State Key Laboratory of Veterinary Etiological BiologyKey Laboratory of Veterinary Parasitology of Gansu ProvinceLanzhou Veterinary Research InstituteChinese Academy of Agricultural SciencesLanzhou730046China Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Disease and Zoonosis Yangzhou UniversityYangzhou225009China

African swine fever virus(ASFV)is an important pathogen that causes a highly contagious and lethal disease in swine,for which neither a vaccine nor treatment is available.The DNA repair enzyme 8-oxoguanine DNA glycosylase 1(OGG1),which excises the oxidative base lesion 8-oxo-7,8-dihydroguanine(8-oxoG),has been linked to the pathogenesis of different diseases associated with viral infections.However,the role of OGG1-base excision repair(BER)in ASFV infection has been poorly investigated.Our study aimed to characterize the alteration of host reactive oxygen species(ROS)and OGG1 and to analyse the role of OGG1 in ASFV infection.We found that ASFV infection induced high levels and dynamic changes in ROS and 8-oxoG and consistently increased the expression of OGG1.Viral yield,transcription level,and protein synthesis were reduced in ASFV-infected primary alveolar macrophages(PAMs)treated by TH5487 or SU0268 inhibiting OGG1.The expression of BER pathway associated proteins of ASFV was also suppressed in OGG1-inhibited PAMs.Furthermore,OGG1 was found to negatively regulate interferonβ(IFN-β)production during ASFV infection and IFN-βcould be activated by OGG1 inhibition with TH5487 and SU0268,which blocked OGG1 binding to 8-oxoG.Additionally,the interaction of OGG1 with viral MGF360-14-L protein could disturb IFN-βproduction to further affect ASFV replication.These results suggest that OGG1 plays the crucial role in successful viral infection and OGG1 inhibitors SU0268 or TH5487 could be used as antiviral agents for ASFV infection.

关键词： African swine fever virus(ASFV) 8-oxoguanine DNA glycosylase 1(OGG1) 8-oxo-7,8-dihydroguanine(8-oxoG) Inhibitors Antiviral effect

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

北京大学图书馆古籍保护实验室的建设与思考

大学图书馆学报 2021年第4期39卷 105-110页

作者：吕淑贤张艳霞北京大学图书馆北京100871

建设古籍保护实验室对提高图书馆古籍保护业务的科学技术水平、培养古籍保护人才具有重要意义。北京大学图书馆古籍保护实验室于2019年初正式运行,下设物理性能实验室、模拟老化实验室、精密仪器实验室、化学实验室和预防性保护实验室... 详细信息

建设古籍保护实验室对提高图书馆古籍保护业务的科学技术水平、培养古籍保护人才具有重要意义。北京大学图书馆古籍保护实验室于2019年初正式运行,下设物理性能实验室、模拟老化实验室、精密仪器实验室、化学实验室和预防性保护实验室共五个实验室,配备了一流的硬件设施。文章调研了国内外古籍保护实验室现状,阐述了北京大学图书馆古籍保护实验室建设的目的、意义、定位以及设计思路,并通过回顾实验室的建设历程,总结实验室建设中的六点经验,在此基础上探讨实验室的建设特色与优势,展望未来发展前景。

关键词：图书馆古籍保护实验室建设

数据分析抢先机:图书馆大数据资料的活化与加值应用

在线全文

学校读者我要写书评

暂无评论

新世纪图书馆 2023年第11期 10-15页

作者：曾淑贤吕宝桂洪伟翔汉学研究中心中国台湾台北100201 汉学研究中心图书馆事业发展组中国台湾台北100201

鉴于图书馆运用数据分析之趋势,为了解台湾地区读者的阅读风貌,并协助各县市公共图书馆掌握读者阅读兴趣,汉学研究中心与各县市公共图书馆携手合作,建置台湾地区第一个图书馆大数据服务平台,以各县市公共图书馆读者去识别化阅读兴趣资... 详细信息

鉴于图书馆运用数据分析之趋势,为了解台湾地区读者的阅读风貌,并协助各县市公共图书馆掌握读者阅读兴趣,汉学研究中心与各县市公共图书馆携手合作,建置台湾地区第一个图书馆大数据服务平台,以各县市公共图书馆读者去识别化阅读兴趣资料为核心,透过数据资料清理整并、大数据分析技术之运用,以及视觉化工具之辅助,协助图书馆了解读者利用图书馆的情形,进而作为推动图书馆阅读与馆藏发展政策等之参考。

关键词：公共图书馆大数据数据可视化数据分析

泛在信息环境下我国大学图书馆人力资源管理对策研究——以北京大学图书馆为例

在线全文

学校读者我要写书评

暂无评论

大学图书馆学报 2016年第6期34卷 28-34页

作者：裴微微吕淑贤萧群北京大学图书馆北京100871

在调研泛在信息社会与泛在图书馆的理论及国内外研究概况的基础上,对泛在信息社会对我国大学图书馆人力资源管理的影响进行了探讨,进而以北京大学图书馆为例,提出泛在信息环境下我国大学图书馆人力资源管理的对策和发展思路。

关键词：泛在信息社会泛在图书馆人力资源管理

在线全文

学校读者我要写书评

暂无评论

二氯喹啉酸农药中盐的鉴别方案研究

现代农药 2022年第1期21卷 35-38页

作者：徐成辰吕霞杨淑娴吴晗江苏省农产品质量检验测试中心南京210036

本研究建立一套鉴别二氯喹啉酸产品中二氯喹啉酸盐的实验室检测方案,并提出相应的监管建议。采用“外观鉴别法”“含量鉴别法”和“离子色谱法”对二氯喹啉酸产品中的二氯喹啉酸盐和反离子对进行鉴定,可以区分产品中是否含有二氯喹啉酸... 详细信息

本研究建立一套鉴别二氯喹啉酸产品中二氯喹啉酸盐的实验室检测方案,并提出相应的监管建议。采用“外观鉴别法”“含量鉴别法”和“离子色谱法”对二氯喹啉酸产品中的二氯喹啉酸盐和反离子对进行鉴定,可以区分产品中是否含有二氯喹啉酸盐以及盐的种类。该套鉴别方案成熟、可靠,应用场景多样,结合具体监管措施,可用于规范二氯喹啉酸农药的生产。

关键词：二氯喹啉酸二氯喹啉酸盐鉴别市场监管

高效液相色谱法测定高效氯氟氰菊酯微囊悬浮剂的优化研究

在线全文

学校读者我要写书评

暂无评论

现代农药 2024年第3期23卷 57-61页

作者：王坤吕霞刘贝妮吴晗杨淑娴江苏省农产品质量检验测试中心南京210000

在现有检测方法的基础上,研究了不同溶剂的破囊效果,建立了高效液相色谱法测定高效氯氟氰菊酯微囊悬浮剂中有效成分含量的方法。方法以乙醇为破囊溶剂,正己烷+乙醇为流动相,使用ZORBAX RX-SIL色谱柱和可变波长紫外检测器,在278 nm波长... 详细信息

在现有检测方法的基础上,研究了不同溶剂的破囊效果,建立了高效液相色谱法测定高效氯氟氰菊酯微囊悬浮剂中有效成分含量的方法。方法以乙醇为破囊溶剂,正己烷+乙醇为流动相,使用ZORBAX RX-SIL色谱柱和可变波长紫外检测器,在278 nm波长下对高效氯氟氰菊酯微囊悬浮剂进行分离和定量分析。结果表明,在质量浓度0.05~1.0 mg/mL时,方法线性关系良好,相关系数为0.9999;方法标准偏差为0.06,相对标准偏差为0.55%,平均回收率为100.81%。该分析方法操作简易、安全、准确,分离效果好,可用于高效氯氟氰菊酯微囊悬浮剂有效成分的分析检测。

关键词：高效氯氟氰菊酯微囊悬浮剂破囊高效液相色谱分析

Assessment of left ventricular segmental function after autologous bone marrow stem cells transplantation in patients with acute myocardial infarction by tissue tracking and strain imaging

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2005年第14期118卷 1175-1181页

作者： RUANWen PANCui-zhen HUANGGuo-qian LIYan-lin GEJun-bo shuxian-hong DepartmentofCardiology ZhongshanHospitalofFudanUniversityShanghai200032China

Background Emerging evidence suggests that stem cells can be used to improvecardiac function in patients after acute myocardial infarction. In this randomized trial, we aimedto use Doppler tissue tracking and strain imaging to assess left ventricular segmental functionafter intracoronary transfer of autologous bone-marrow stem cells ( BMCs) for 6 months' follow up.Methods Twenty patients with acute myocardial infarction and anterior descending coronary arteryocclusion proven by angiography were double-blindedly randomized into intracoronary injection ofbone-marrow cell (treated, n = 9 ) or diluted serum ( control, n = 11) groups. GE vivid 7 andQ-analyze software were used to perform echocardiogram in both groups 1 week, 3 months and 6 monthsafter treatment. Three apical views of tissue Doppler imaging were acquired to measure peak systolicdisplacement ( D_s) and peak systolic strain (ε_(peak)) from 12 segments of lv walls. Leftventricular ejection fraction (lvEF), end-diastolic volume (EDV) and end-systolic volume ( ESV) wereobtained by Simposon's biplane method. Results (1) 3 months later, D_a and ε_(peak) over theinfract-related region clearly increased in the BMCs group [D_8: (4.49 ±2.71) mm vs (7.56 ±2.95)mm, P 0.05; ε_(peak): ( - 13.84 ± 6.05) %vs ( - 15.04 ± 6.75) % , P > 0.05 ]. At the same time, D_s over the normal region also increased,but the D_8 enhancement was markedly higher in the BMCs group than that in the control group [ (3.21±3.17) mm vs (0.76 ± 1.94) mm, P 0.05). (2) lvEF in treated and control groups were almost the same at baseline (1st week after PCI) [ (53.37 ± 8.92) % vs (53.51 ± 5.84) % , P > 0.05 ]. But 6 months later, lvEFin the BMCs group were clearly higher than that in the control group [(59.33 ± 12.91)% vs (50.30 ±8.30)%, P < 0.05 ]. (3) There were no evident d

关键词： echocardiography tissue doppler imaging acute myocardial infarction bonemarrow stem cells cell transplantation