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微藻生物系统去除抗生素和ARGs的研究进展

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净水技术 2024年第4期43卷 28-33,45页

作者：赵学宇任淑静郭宁张欢欢贾玉莹朱兆亮山东建筑大学市政与环境工程学院山东济南250101

抗生素与抗生素抗性基因(ARGs)污染严重危害人类健康,微藻生物技术在处理抗生素废水过程中表现出良好的效果。文章首先总结了微藻对于不同种类抗生素的去除机理,包括生物吸附、生物累积、生物降解、光生物降解和水解挥发5种。分析了微... 详细信息

抗生素与抗生素抗性基因(ARGs)污染严重危害人类健康,微藻生物技术在处理抗生素废水过程中表现出良好的效果。文章首先总结了微藻对于不同种类抗生素的去除机理,包括生物吸附、生物累积、生物降解、光生物降解和水解挥发5种。分析了微藻在去除抗生素过程中的重要影响因素,包括pH、水力停留时间、光照、抗生素的种类与浓度和微藻的种类。并总结了微藻对ARGs的去除机制,包括移动基因元件的去除及活性氧自由基的猝灭。最后,文章指出了微藻处理抗生素废水过程中仍然存在的问题,进一步明确了今后微藻生物技术处理抗生素废水的重点研究方向。

关键词：抗生素废水微藻抗生素抗性基因(ARGs) 去除机理影响因素

Better design leads to better results-Importance of virological outcome design in clinical trials for antiviral treatment of coronavirus disease 2019

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Pediatric Investigation 2023年第1期7卷 1-5页

作者： Getu Zhaori Lu Lu Chunyan Liu shujing Han Yongli guo Editorial Office Pediatric InvestigationBeijing Children’s HospitalCapitalMedical UniversityNational Center for Children’s HealthBeijingChina Medical Journal Center Beijing Pediatric Research InstituteBeijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijingChina Beijing Key Laboratory for Pediatric Diseases of Otolaryngology Head and Neck SurgeryMOE Key Laboratory of Major Disease in ChildrenBeijing Pediatric Research InstituteBeijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijingChina

Since the outbreak of the pandemic coronavirus disease 2019(COVID-19),various articles on different fields of the disease published in medical and related journals increased in a way of explosion.A recent literature s... 详细信息

关键词： clinical treatment explosion

Microstructural Characteristics and Gas-bearing of the Upper Cretaceous Qingshankou Formation Shale,Southern Songliao Basin

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Acta Geologica Sinica(English Edition) 2015年第A1期89卷 31-32页

作者： GE Mingna REN Shoumai BAO shujing ZHOU Zhi guo Tianxu Oil & Gas Survey of China Geological Survey

Southern Songliao basin consists of four A structural units from west to east： western slopes, southwest ridge, central depression and southeast uplift. Upper Cretaceous Qingshankou Formation shale sedimented in large-scale invasion of the lake, with a quick settlement, super fast filling compensation deposition characteristics and widely deposition of organic-rich, thick black shale interbedded oil shale, which is the most important source rocks on Songliao basin.

关键词： SHALE gas RESEARCH SHALE oils MICROPORES BASINS (Geology) SCANNING electron microscopes CHINA

Mapping a mammalian adult adrenal gland hierarchy across species by microwell-seq

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Cell Regeneration 2020年第1期9卷 110-121页

作者： shujing Lai Lifeng Ma Weigao E Fang Ye Haide Chen Xiaoping Han guoji guo Center for Stem Cell and Regenerative Medicine Zhejiang University School of MedicineHangzhou 310058China Bone Marrow Transplantation Center The First Affiliated HospitalZhejiang University School of MedicineHangzhou 310009China Institute of Hematology Zhejiang UniversityHangzhou 310058China

Recently,single-cell RNA-seq technologies have been rapidly updated,leading to a revolution in *** previously developed Microwell-seq,a cost-effective and high-throughput single cell RNA sequencing(scRNA-seq)method with a very simple *** cDNA libraries are sequenced using an expensive Illumina ***,we present the first report showing combined Microwell-seq and BGI MGISEQ2000,a less expensive sequencing platform,to profile the whole transcriptome of 11,883 individual mouse adult adrenal gland cells and identify 18 transcriptionally distinct ***,we performed a single-cell comparative analysis of human and mouse adult adrenal glands to reveal the conserved genetic networks in these mammalian *** results provide new insights into the sophisticated adrenal gland hierarchy and provide a benchmark,low-cost strategy for highthroughput single-cell RNA study.

关键词： adrenal Mapping seq

Enhancement and recovery of photoluminescence and stability by multifunctional etching ligands treatment for perovskite nanocrystals

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Journal of Energy Chemistry 2023年第1期76卷 495-502,I0013页

作者： Yang Zhao Haipeng Zeng Xueqing Cai Yingshan Zhou Yangming Jiang Xin Zheng Lin Li shujing Zhang Long Luo Weixi Li Xiaoru Zhang Ranran Liu Wenxi Liang Rui guo Xiong Li Michael Gratzel Center for Mesoscopic Solar Cells Wuhan National Laboratory for OptoelectronicsHuazhong University of Science and TechnologyWuhan 430074HubeiChina State Key Laboratory of New Textile Materials and Advanced Processing Technologies Wuhan Textile UniversityWuhan 430073HubeiChina State Key Laboratory of Functions and Applications of Medicinal Plants Guizhou Medical University Guiyang 550014GuizhouChina

Perovskite nanocrystals(PNCs)have recently become promising optoelectronic materials due to their excellent photophysical ***,the highly dynamic binding state between ligands and the surface of PNCs has severely restricted their luminescent properties and *** this work,1,3-bisbenzyl-2-oxoimidazolidine-4,5-dicarboxylic acid(cycle acid,CA)is introduced as both an etchant and a ligand upon post-synthetic surface treatment of *** removing the imperfect octahedrons[Pb X_(6)]^(4-)and passivating the surface defects synergistically,this treatment improves photoluminescence quantum yields from 76%to 95%and enhances the stability of PNCs against polar solvent,moisture,heat,and ***,CA can effectively and instantly recover the luminescence emission for aged *** a result,the CA-Cs Pb Br_(3)PNCs and CA-Cs Pb IxBr_(3-x)PNCs are applied as color-converting layers on a blue LED chip for warm white light-emitting diodes(WLEDs)with a color coordinate of(0.41,0.40).Importantly,the CA-based WLED device exhibits superior stability in operational conditions.

关键词： Perovskite nanocrystals Synergistic effect Emission recovery White light emitting diodes Stability

酮咯酸氨丁三醇复合舒芬太尼超前镇痛对腹腔镜子宫切除术后的镇痛作用

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中国计划生育学杂志 2022年第2期30卷 327-331页

作者：陈伟胡北郭淑静高楝南京鼓楼医院集团宿迁市人民医院 223800

目的:探讨酮咯酸氨丁三醇复合舒芬太尼用于子宫切除患者术后超前镇痛效果及安全性。方法:选取本院2018年1月-2020年1月择期行腹腔镜子宫切除术患者184例,随机分为观察组(n=92)和对照组(n=92)。两组患者均于手术切皮前30min超前镇痛给药... 详细信息

目的:探讨酮咯酸氨丁三醇复合舒芬太尼用于子宫切除患者术后超前镇痛效果及安全性。方法:选取本院2018年1月-2020年1月择期行腹腔镜子宫切除术患者184例,随机分为观察组(n=92)和对照组(n=92)。两组患者均于手术切皮前30min超前镇痛给药,对照组给予10μg舒芬太尼,观察组给予5μg舒芬太尼+15mg酮咯酸氨丁三醇。术毕均连接自动控制镇痛泵PCIA,对照组使用1μg/kg舒芬太尼,观察组使用3mg/kg酮咯酸氨丁三醇复合1μg/kg舒芬太尼。观察两组患者术毕清醒即刻(T1)、术后2h(T2)、6h(T3)、12h(T4)、24h(T5)及撤PCIA后2h(T6)的视觉模拟评分法(VAS)评分;检测患者手术麻醉前(T0)、T2、T5血清P物质和五羟色胺(5-HT)水平;记录术后镇痛不良反应。结果:VAS评分观察组术后T1(2.95±0.77分)、T2(3.41±0.75分)、T3(3.12±0.79分)时低于对照组(3.33±0.69分、3.86±0.84分、3.45±0.75分)(P0.05);观察组术后T2、T5、T6时血清P物质、5-HT水平均低于对照组,镇痛不良反应总发生率(5.4%)低于对照组(15.2%)(均P<0.05)。结论:酮咯酸氨丁三醇复合舒芬太尼用于子宫切除超前镇痛,可显著降低患者术后早期血清致痛物质水平,术后镇痛效果好且不良反应发生率低。

关键词：腹腔镜子宫切除手术超前镇痛酮咯酸氨丁三醇舒芬太尼镇痛效果

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中医药文化融入高中生物学教学的研究

赤峰学院学报（自然科学版） 2024年第7期40卷 103-108页

作者：田怡丰李晓兰赵晨霞田慧敏申玉华郭颖贾姝婧赤峰学院化学与生命科学学院内蒙古赤峰024000 伊犁师范大学资源与环境学院新疆伊犁835000 赤峰市红旗中学内蒙古赤峰024000

中医药文化作为中华传统文化的重要组成部分,蕴含着丰富的科学知识、人文精神、生命价值和养生智慧,是中华民族宝贵的文化遗产。将中医药文化融入高中生物学教学不仅可以提高学生的健康意识,并且对学生树立正确的三观,提高学生民族自豪... 详细信息

中医药文化作为中华传统文化的重要组成部分,蕴含着丰富的科学知识、人文精神、生命价值和养生智慧,是中华民族宝贵的文化遗产。将中医药文化融入高中生物学教学不仅可以提高学生的健康意识,并且对学生树立正确的三观,提高学生民族自豪感和文化自信也有极大帮助。目前我国中医人才培养多集中于高校,能在高中阶段对学生进行中医药文化渗透,对中医药的发展和传承具有促进作用。本文结合当前生物学教学现状,以人教版高中生物教材中的生物学知识为依托,分析了将中医药文化融入高中生物教学中的必要性和教学策略,旨在提高学生学习生物学的兴趣和热情,激发学生对生命科学研究的兴趣。

关键词：中医药文化高中生物学教学策略

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酒石酸布托啡诺注射液对剖宫产产妇术后自控静脉镇痛的影响

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世界复合医学 2022年第9期8卷 165-168页

作者：李静郑向欣郭淑静李楠胡北南京鼓楼医院集团宿迁医院麻醉科江苏宿迁223800

目的探讨酒石酸布托啡诺注射液对剖宫产产妇术后自控静脉镇痛的影响。方法选取2020年6月—2021年12月南京鼓楼医院集团宿迁医院收治的剖宫产产妇92名,按照随机数表法分为对照组与观察组,各46名。对照组采用100μg舒芬太尼融入生理盐水至... 详细信息

目的探讨酒石酸布托啡诺注射液对剖宫产产妇术后自控静脉镇痛的影响。方法选取2020年6月—2021年12月南京鼓楼医院集团宿迁医院收治的剖宫产产妇92名,按照随机数表法分为对照组与观察组,各46名。对照组采用100μg舒芬太尼融入生理盐水至100 mL实施自控静脉镇痛,观察组采用12 mg酒石酸布托啡诺注射液融入生理盐水至100 mL实施自控静脉镇痛,比较两组视觉模拟评分法(VAS)评分、舒适量表(BCS)评分、Ramsay镇静评分及不良反应发生率。结果观察组术后8、24、48、72 h的VAS评分分别为(2.50±0.40)分、(2.17±0.32)分、(1.80±0.25)分、(1.41±0.22)分,BCS评分分别为(2.28±0.41)分、(2.42±0.31)分、(2.85±0.44)分、(3.04±0.28)分,与对照组比较,差异无统计学意义(P>0.05);观察组术后8、24、48 h的Ramsay镇静评分高于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率为6.52%,低于对照组的21.74%,差异有统计学意义(χ^(2)=4.390,P<0.05)。结论酒石酸布托啡诺注射液应用于剖宫产产妇术后自控静脉镇痛的效果确切,同时可取得比舒芬太尼更好的镇静效果,可减少不良反应的发生。

关键词：剖宫产自控静脉镇痛酒石酸布托啡诺注射液舒芬太尼镇静不良反应

Magnetic phase diagram of single-layer CrBr_(3)

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Chinese Physics B 2021年第12期30卷 577-582页

作者： Wei Jiang Yue-Fei Hou shujing Li Zhen-guo Fu Ping Zhang Institute of Applied Physics and Computational Mathematics Beijing 100088China Beijing University of Chemical Technology Beijing 100029China School of Physics and Physical Engineering Qufu Normal UniversityQufu 273165China

We theoretically provide a magnetic phase diagram for the single-layer(SL)CrBr_(3),which could be effectively tuned by both strain engineering and charge doping in SL-CrBr_(3).Through systematical first-principles calculations and Heisenberg model Hamiltonian simulations,three different magnetic phases in SL-CrBr_(3),which are off-plane ferromagnetic,in-plane ferromagnetic and in-plane Neél-antiferromagnetic phases,are found in the strain and charge doping regimes we ***,our results show that higher order Heisenberg exchange parameters and anisotropy exchange parameters should be taken into account for accurately illustrating the magnetic phase transition in SL-CrBr_(3).As a result,we find from the SpinW simulation that the Curie temperature is about T_(c)=38.4 K,which is well consistent with the experimental result 34 K[Nano Lett.193138(2019)].The findings here may be confirmed in future experiments,and may be useful for the potential applications of SL-CrBr_(3)in spintronics field.

关键词： magnetic anisotropy single-layer CrBr_(3) Néel-antiferromagnetic phase